"Suprax" in the treatment of sore throat: an antibiotic for the treatment of sore throat in children and adults

The causes of inflammation of the ENT organs can be various factors. Only a doctor can make an accurate diagnosis. Incorrect treatment entails serious complications and consequences.

For a long time, specialists prescribed antibacterial drugs of the penicillin group to patients with acute tonsillitis. Today, Suprax is increasingly used for sore throat in children and adults. It is important to carefully study the instructions and adhere to the doctor's orders.

In what cases is it prescribed?

Does taking Suprax help with sore throat and in what situations is it justified? The drug is a third-generation antibiotic belonging to the class of cephalosporins (the active substance is cefixime). It is highly effective against streptococci, pneumococci, Klebsiella, Shigella, and other bacteria.

If the disease was caused by microorganisms sensitive to the drug, it will speed up recovery. It is in these cases that Suprax should be prescribed. Among diseases of the ENT organs, indications for antibiotic therapy include purulent tonsillitis, acute tonsillitis, sinusitis, sinusitis, pharyngitis, tracheitis, and otitis media.

Suprax and its properties

Suprax is produced by Jazeera Pharmaceutical Industries (JSC) in several dosage forms:

Contraindications

The drug has age restrictions. The use of Suprax for angina in children under 6 months is prohibited.

It is also contraindicated in case of intolerance to penicellins and cephalosporins. The drug should not be used if there are abnormalities in the functioning of the kidneys and/or liver, severe anemia, diabetes, or colitis.

Women often have a question: is it possible for pregnant and lactating women to take Suprax for a sore throat? During the period of bearing a child, the drug is used with caution, in the dosage specified by the doctor. Nursing mothers need to switch their baby to formula during treatment.

Antibiotic Suprax: description of the drug

Indications
Contraindications

Antibacterial therapy is necessary to treat diseases caused by bacteria.

Given the resistance of pathogenic microorganisms to chemicals, more advanced antibiotics are being developed that can cope with such bacteria.

One of the modern drugs of the third generation cephalosporin group is the antibiotic Suprax.

Its effectiveness is confirmed by both doctors and patients.

Composition and release form

The active substance of the antibiotic is cefixime trihydrate. The composition of additional components depends on the dosage form. Granules intended for the treatment of children contain strawberry flavoring and sucrose, which make the medicine palatable.

Suprax is available in capsules with a soluble shell and granules for the preparation of a medicinal suspension. One capsule contains 200 mg or 400 mg of cefixime. The dosage form is packaged in six pieces in contour cells and a cardboard box.

The granules are in a dark glass bottle (60 ml). The bottle and measuring spoon are packed in a cardboard box. 5 ml of the finished suspension contains 100 mg of cefixin.

The antibiotic Suprax solutab contains 400 mg of active substance. Available in the form of tablets, packaged in blisters of 1, 5 or 7 pieces and cardboard boxes.

Effect of the drug

The main area of application of the drug is otolaryngology. It is considered one of the most effective remedies for treating sore throat. Infectious and inflammatory diseases of the pharynx and pharynx are often accompanied by swelling and hyperemia of the mucous membranes, high fever, chills and pain.

Such symptoms occur when tissues are damaged by gram-positive bacteria, especially streptococci, staphylococci, pneumococci, and in some cases gram-negative bacteria - Klebsiella, Haemophilus influenzae and others. The antibiotic Suprax is equally effective against all these types of bacteria.

In order to determine the pathogen and its sensitivity to antibiotic substances, bacterial culture of the throat contents is done. The results of the analysis take some time to prepare, and the patient needs to be prescribed treatment immediately, so doctors prescribe broad-spectrum drugs, including Suprax.

For the treatment of ENT diseases, antibiotics from the penicillin group are often prescribed. They act relatively gently on the body, without causing severe dysbacteriosis. Penicillins are the drugs of choice for pregnant women and babies.

However, these antibacterial agents have their drawbacks - they cause allergies and do not act on bacteria that synthesize beta-lactamase. The modern drug Suprax does not have such disadvantages, which means that this antibiotic is an excellent alternative to penicillin drugs.

Cefixime inhibits the synthesis of peptidoglycan, which is part of the bacterial membrane. Thus, the membrane membrane is perforated and the microorganism dies. Some types of staphylococcus are resistant to the action of the antibiotic Suprax, which cause sore throat in no more than 10% of cases. The medicine is non-toxic and can be used to treat infants from the age of six months.

Pharmacokinetics

The drug is absorbed by the body regardless of food intake. The bioavailability of the active substance is about fifty percent. Cefaxin binds to plasma proteins, mainly albumin.

The substance has its maximum effect four hours after administration. Cefixin is excreted primarily in urine and partially in bile during the day.

Suprax is prescribed for various infectious diseases caused by bacteria that are sensitive to it.

It is successfully used to treat the respiratory tract, soft tissues, skin, and genitourinary tract.

For what diseases is Suprax prescribed for children:

laryngitis, pharyngitis, sore throat, tonsillitis;
sinusitis (sinusitis, ethmoiditis, frontal sinusitis);
acute or chronic tracheitis;
otitis media, mastoiditis;
bronchitis in acute or chronic forms;
cystitis, pyelonephritis;
scarlet fever.

Suprax is also effective in treating purulent infections of bones, skin and subcutaneous tissue. For adults, the drug can be prescribed to treat gonorrhea.

Before treatment with Suparks, it is advisable to do an antibiotic sensitivity test. Depending on the age, form and severity of the disease, the doctor determines the dosage regimen and course of treatment. Suprax for young children is recommended to be divided into two doses, although, according to the instructions, this remedy is taken once a day.

Dosage by age

Treatment of sore throat with Suprax lasts from five to seven days. Typically, acute symptoms disappear within two or three days. However, antibacterial therapy should not be interrupted or extended; the pediatrician’s recommendations should be strictly followed.

The dosage of Suprax for children under twelve years of age can be calculated at 8 mg of suspension per 1 kg of body weight or follow the recommendations by age:

infants from six months of age should be given 2.5 - 4 ml;
from one year of age the dose is increased to 5 ml;
after five years, the dosage is 6 - 10 ml;
From the age of twelve, children are prescribed 1 capsule per day, that is, 400 mg.

If a twelve-year-old teenager has a body weight below fifty kilograms, then the dose of the medicine should be calculated based on the actual weight.

Example of dose calculation:

The dosage of cefixin in 5 milliliters is 100 mg. If the child weighs 15 kg, then you need to multiply this figure by 8 mg, you get 120 mg, which approximately corresponds to 5 ml. If the medicine is divided into two doses, then it should be given to the child in the morning and evening, with an interval of 12 hours.

It should be remembered that Suprax is not prescribed for children under 6 months of age.

How to prepare a suspension from granules

The suspension is prepared immediately before treatment. The granules are diluted with cool boiled water in a volume of 40 ml. Dilution of dry matter is carried out in two steps. First, pour half the water and shake the bottle, then add the remaining water and shake again. The bottle is left for a while so that the granules dissolve well.

Before each use, the bottle must be shaken well. The required dose is measured with a special measuring spoon. It is advisable to give the medicine to the child at the same time, regardless of meals. Children are happy to take this treatment, as the drug tastes and smells pleasant.

The finished suspension should be stored in the refrigerator. It can only be used for one course of treatment. If there is any medicine left after therapy, it should be thrown away.

How to take capsules

Teens and adults take one 400 mg capsule daily. The time for taking the medicine should be the same. If you start taking capsules in the morning, you should take the next one at the same time. Capsules containing 200 mg of active substance are taken every 12 hours. The course of treatment should not exceed ten days. Streptococcal infections are always treated with the maximum course.

Suprax for sore throat in children: who is contraindicated and what to replace it with

Cephalosporins cope well with lacunar and purulent forms of tonsillitis. They quickly relieve young patients from sore throat, fever and other unpleasant symptoms.

The famous TV presenter Dr. Komarovsky believes that antibiotics are necessary in the treatment of children, but only for diseases caused by bacteria.

In addition to bacterial etiology, sore throat can be of a viral nature, for example, herpetic. Mononucleosis, characterized by a viral infection of the pharynx, can also be mistaken for a sore throat. In this case, Suprax for sore throat in children will not only be useless, but will also cause serious harm to health.

By killing the immune cells that fight the virus, it will become an obstacle for the body on the path to recovery. Therefore, you cannot decide on your own whether to treat your child with antibiotics, but should consult a doctor and undergo appropriate diagnostics.

Contraindications

The following are considered absolute contraindications:

individual intolerance to cephalosporins;
serious renal dysfunction;
age up to six months;
age up to twelve years (in relation to capsules).

The following should be prescribed with caution:

during pregnancy and lactation;
for diabetes mellitus;
persons with renal failure;
To old people;
for colitis (inflammation of the large intestine).

Suprax is not usually prescribed during pregnancy. An exception may be cases when other drugs do not bring the desired therapeutic effect. Such treatment can only be prescribed by a doctor who can assess all the risks to the fetus.

With long-term use of cephalosporins, the balance of intestinal microflora is seriously disturbed, clostridia multiply, severe diarrhea occurs, and abdominal pain appears.

Side effects

Suprax for angina in children is prescribed as a course of treatment for no more than 7 days. Even though it can be used from 6 months, the antibiotic still has serious side effects. Therefore, the drug should be taken strictly under the supervision of a doctor.

Possible side effects that occur most often include dyspepsia, characterized by nausea, vomiting and loose stools. Dysbacteriosis develops no less rarely, and allergic skin reactions occur: rash, redness and itching.

Side effects from the use of cephalosporin antibiotics can be more pronounced: anaphylactic shock, immune disorder, impaired liver and kidney function, dizziness, pathological changes in blood composition, jaundice, stomatitis, dysbacteriosis, convulsions and a number of others.

You should not refuse to take the drug solely on the basis of an impressive list of side effects. The doctor takes all of them into account when prescribing antibacterial therapy for the baby. Any antibiotic can lead to a deterioration in health, but serious problems usually occur against the background of pre-existing pathologies.

Prices and analogues of the drug

The cost of Suprax in granules is 570 rubles, in capsules - 720 rubles. The price of Surpax Slutab tablets is 840 rubles.

Direct analogues of Suprax, prescribed for angina in children, are the following drugs:

Pancef - granules cost 450 rubles, tablets - 540 rubles;
Ixim Lupine - the price of the powder is 450 rubles;
Cefix - tablets can be bought for 600 rubles.

Analogs of the drug for therapeutic effect can be found in other groups of antibacterial agents:

From the group of macrolides we can distinguish an antibiotic such as Klacid. The main active ingredient is clarithromycin. The tablets have a quick and powerful effect, but they also have a very long list of side effects.
From the penicillin group, Amoxiclav is popular. The antibiotic is weaker than the previous ones, but has less negative effects on the body.
Azalids are represented by Sumamed. This broad-spectrum antibiotic is often prescribed to children for sore throat and other diseases of the ENT organs.
From the group of cephalosporins, in addition to Suprax, Ceftriaxone may be prescribed.

Reviews

Elena Semikova:

“My son is 4 years old. In kindergarten, the temperature suddenly rose, it turned out that she had a sore throat. They called a doctor to the house, he prescribed Amoxiclav. But after four days of taking the medicine, there was no relief. The attending physician changed the treatment in favor of Suprax. The temperature dropped the very next day, and my son began to feel much better.”

Ekaterina Novikova:

“I have two children, 5 and 8 years old. Suprax has helped many times in the treatment of otitis media and tonsillitis. No complications were observed in children. Making the suspension is very quick and easy, and children drink it without hostility, unlike tablets.”

gajmorit.com

Instructions and dosage

The use of the drug is permissible only after a diagnosis has been established. The dosage of Suprax depends on the severity of the disease, the age and body weight of the patient, if we are talking about a child.

For children

Suprax for purulent sore throat in children aged 6 months to 12 years is used in the form of a suspension. To prepare it, add boiled and cooled water (40 ml) to the bottle with granules. Then the drug must be shaken until a homogeneous composition is obtained.

The suspension can be stored for no more than 2 weeks at temperatures up to 25 °C. It should be shaken well before use.

The dosage of the drug for a child is 8 mg/kg body weight. This amount can be taken by children one or two times (every 12 hours). The recommended daily dose depends on the age of the child: 2.5-4 ml - from 6 to 12 months, 5 ml at 2-4 years, 6-10 ml at 5-11 years, etc. The duration of the course is determined by the attending physician and is individual in every case.

For adults

Taking Suprax for angina in adults usually occurs once a day (dosage - 400 mg). Children over 12 years old, provided that their weight is at least 50 kg, take the drug in the same way.

Duration of treatment is 5-10 days. It is important to complete the course completely, otherwise the bacteria will not die and will become immune to this drug. Due to the negative effect of Suprax on the intestinal microflora, taking probiotics is recommended after its use.

Features of Suprax as an antibiotic for the treatment of sore throat in children

Photo. Suprax suspension, granules and tablets for the treatment of sore throat

The properties of Suprax are due to Cefixime trihydrate, which determines the antibacterial effect of the antibiotic. The instructions describe how it works.

For ease of use, Suprax is available in the following dosage forms:

granules for the preparation of children's suspension include strawberry flavoring, sucrose to give a pleasant taste to the medicine when it is prescribed to children;
gelatin capsules containing granules for oral administration, designed to protect the active substance from the action of gastric juice;
glass bottles with a capacity of 60 ml containing granules for preparing a suspension, packaged in a cardboard box with a measuring spoon;
Suprax Solutab tablets in the form of tablets, packaged in blisters containing 400 mg of Cefixime trihydrate.

Suprax is mainly used to treat diseases of the nasopharynx, which are accompanied by fever, pain, swelling, and hyperemia of the throat mucosa. The drug has proven to be especially effective for the treatment of purulent tonsillitis, lacunar and follicular. The characteristic symptoms of tonsillitis are caused by pneumococci, staphylococci, streptococci, as well as Klebsiella and other pyogenic microorganisms.

To determine the causative agent of a sore throat, a smear is made from the mucous membrane of the throat and cultured, but this takes time. In this case, for treatment it is necessary to use an antibiotic that acts on many groups of microorganisms, which is Suprax. Penicillins are best suited for the treatment of colds, since they do not cause dysbiosis in the intestines, but many modified varieties of bacteria have now appeared that are resistant to them.

The active substance Supraxa Cefixime does not have the disadvantages of penicillin, therefore it is successfully used to replace it. The advantage of Suprax is its safety.

Use of Suprax in children

Suprax is used for children not only to treat sore throat, but also the following diseases:

Sore throat, acute and chronic.
Bronchitis.
Laryngitis.
Mastoiditis.
Otitis.
Pyelonephritis.
Sinusitis.
Tracheitis.
Pharyngitis.
Cystitis.

After checking for sensitivity, Suprax is given to children twice a day, although according to the instructions a single dose is prescribed. After starting to take it, the symptoms of sore throat disappear within two days, and the entire course is recommended to be continued for up to 7 days in children and up to 10 in adults.

Recommended for children:

Infants from 6 months of age are given the drug in the form of a suspension twice a day as prescribed by a doctor;
at the age of one to 5 years, increase the amount of suspension to 5 ml per day;
from 5 to 12 years old, children are given from 6 to 10 ml of suspension per day;
from the age of 12, children can be given capsules, 1 per day, containing 400 mg of the drug;
1 ml of suspension contains 20 mg of Cefixime.

Preparation of the suspension:

It is necessary to boil and cool water.
Shake the bottle containing the granules with the drug vigorously.
First pour 20 ml of water, shake, add another 20 ml and repeat shaking until a homogeneous suspension is obtained.
It is necessary to allow the suspension to settle for 5-10 minutes.
Each time before use, the bottle with the suspension is shaken to ensure uniformity of the composition.
You can dilute the granules in juice or breast milk.
The prepared suspension should be stored in the refrigerator.

After 12 years of age, children are given Suprax 1 capsule per day, with the same dosage as in adults. It is permissible to take the drug both before and after meals. If the doctor has prescribed capsules in a dosage of 200 mg, then they are used strictly at the same time of day to maintain a uniform concentration of the antibiotic in the blood.

It is necessary to monitor the manifestation of side effects, the main one being intestinal dysbiosis. Only the doctor can make adjustments to treatment.

Analogs of Suprax for the treatment of childhood sore throat

Instead of Suprax, the doctor may prescribe its analogues if severe side effects occur:

Amoxiclav (penicillins).
Glacid (macrolides).

Other classes of antibiotics:

Iximi Pancef (tablets and granules).
Lupine (powder).
Sumamed (azalides).
Cefix (tablets).
Ceftriaxone (cephalosporins).

The choice of antibiotic for the treatment of sore throat belongs to the doctor. Currently, penicillins, cephalosporins, macrolides belonging to various classes of antibiotics complement each other, their combination makes it possible to cope with almost any infectious disease, which includes sore throat.

Side effects

The drug may have undesirable effects on the body. Its side effects include:

candidiasis;
allergic reactions (rash, skin itching, swelling, etc.);
pseudomembranous colitis;
constipation and diarrhea;
nausea, vomiting, abdominal pain;
stomatitis;
cholestasis;
anemia;
convulsions;
dizziness, headache.

Also, when taking Suprax, the functions of the kidneys and liver may be impaired. In case of overdose, the risk of developing these phenomena increases. If the drug was accidentally taken in large doses, the patient should rinse the stomach and go to the hospital.

Suprax or Sumamed?

What is better for angina - Sumamed or Suprax? Both drugs are antibiotics and can be prescribed for this disease, but the active substance in them is different.

The active component of Sumamed is azithromycin, which belongs to the group of macrolides. It successfully fights staphylococcus, streptococcus, clostridia and a number of other aerobic and anaerobic bacteria.

Both Sumamed and Suprax are fairly modern drugs with similar indications and contraindications. The decision about which one is better should be made after determining the sensitivity of pathogens to various groups of antibiotics. Also, the decisive factor may be the patient’s intolerance to the components of one of the products.

In what form is the medicine available?

The antibiotic Suprax has various forms of release, but only for oral use. Let's look at all forms of release and find out what the instructions for using each of them say.

The medicine in the form of a suspension is intended for the treatment of young children. This antibiotic is approved for children from six months of age. The dosage of the suspension is calculated based on the child’s body weight. For 1 kg of child weight, 8 mg of suspension is required. Instructions for use describe basic recommendations for the correct use of the drug:

for babies up to one year of age, the drug should be given in an amount of 3-4 ml
for children from one to 4 years old it is recommended to give 5 ml of medicine
from 4 to 12 years, the suspension is given in an amount of 7-9 ml per day

Before using the medicine, it must be prepared. To do this, add 20 ml of boiled water to a bottle containing granules of the active antibiotic, then mix thoroughly. After the suspension has a uniform consistency, you need to add another 20 ml of water to the level on the bottle.

Other analogues

The antibiotic for angina Suprax can be replaced with another drug with a similar composition. Its analogues, also belonging to the group of cephalosporins:

Pantsef. Contains cefixime, release form - tablets (6 and 10 pieces per package) with a dosage of 400 mg and granules for preparing a suspension (100 ml). The price for a pack of 6 tablets is about 340 rubles, for 10 tablets it’s about 420 rubles. Granules cost about 415 rubles.
Ixim Lupin. The active ingredient is also cefixime. The drug is taken in the form of a suspension. The average price per bottle (50 ml) is 370 rubles.
Claforan. The active ingredient is cefotaxime, dosage – 1000 mg. The drug is used in the form of injections (IV, IM). The cost of one bottle is about 120 rubles.
Ceftriaxone. Contains ceftriaxone, method of administration - IM and IV injections. Price for 1 bottle (dosage – 1000 mg) – about 20 rubles.
Sulperazon. It is administered in the form of injections, the active components are cefoperazone and sulbactam, dosage is 2 g (1g+1g). Price for 1 bottle – from 350 rubles.

Diseases of the ENT organs can have serious consequences, so it is not always possible to do without the use of antibiotics. Suprax and other drugs of the cephalosporin group show good results in the treatment of acute inflammatory processes.

But their independent appointment is unacceptable. Uncontrolled use of antibiotics leads to the development of resistance of pathogenic microorganisms to them, dysbacteriosis and other complications.

Author: Yana Semich, especially for lechim-gorlo.ru

How to take the drug

The antibacterial agent has a wide range of active effects on pathogenic bacteria.

Despite its versatility, before use, it is better to take an antibiotic sensitivity test.

Absorption of the drug occurs in the small intestine and is excreted from the body through the kidneys.

The maximum concentration in the body is reached 4 hours after consumption and is valid for 24 hours.

The dosage can be divided into 2 parts and taken twice a day. This method is used for complex forms of sore throat in order to alleviate the condition in a shorter time.

The course of treatment lasts 5-7 days, depending on the degree of the inflammatory process. The drug is available in a form for internal use.

For adults, tablets are more suitable; for small children, granules are used, from which a suspension is made.

Here's another interesting addition in video format:

This form of release allows you to determine the optimal treatment option for a child. The dosage for children is calculated based on body weight and is 8 mg per kg.

Depending on age, the daily volume of suspension will be in the following ranges:

For babies under one year old, about 3-4 ml;
Children under 4 years old - 5 ml;
From the age of 12 years - 7.5-10 ml.

The drug granules are diluted with water according to the instructions.

The finished suspension should be stored in the refrigerator, so it must be taken out 20-30 minutes before administration so that the baby can take the medicine at room temperature.