Compound
Klacid tablets consist of the active component clarithromycin and excipients: sodium alginate, sodium calcium alginate, anhydrous citric acid hydrogen phosphate, lactose, magnesium stearin.
The drug belongs to the group of macrolides - semi-synthetic antimicrobial drugs, effective in the fight against Staphylococcus aureus, pneumococci, streptococci type A. The drug also shows quite good results in the treatment of diseases caused by hemophilia, gonococci, chlamydia and other representatives of pathogenic microflora.
When should you not take the drug?
It is strictly prohibited to take Klacid tablets in patients suffering from:
- ventricular arrhythmia (or if there is a history of it);
- hypokalemia;
- severe liver failure;
- renal failure (especially if it is accompanied by liver problems).
Before using the drug, it is extremely important to undergo a sensitivity test to its components. Intolerance to at least one of them should be a compelling reason to discontinue the drug and replace it with another medication.
Features of use and dosage
Use of the drug Klacid for the following otolaryngological diseases:
- pharyngitis:
- tonsillitis;
- otitis media;
- purulent sinusitis.
The antibiotic is available in different forms with different dosages of the active substance:
- tablets 250 mg;
- granules for the preparation of oral suspension, 60 and 100 ml;
- tablets from the “SR” prefixes of 500 mg, which have a longer antimicrobial effect;
- powder for preparing a solution intended for jet application using drip systems (but in no case should it be administered using a syringe).
For the treatment of otolaryngological diseases in adults and children, Klacid tablets are often used, although, of course, the dosage and form of the drug are selected exclusively by the attending physician.
Use for sore throat
Klacid for angina gives quite good results within a few days after the start of treatment. With lacunar tonsillitis, the purulent contents of the tonsils resolve in approximately 48-74 hours. Although the effectiveness of therapy depends on the patient’s age and the form of the drug. In addition, the severity of the pathology and the presence of its complications play an important role.
The drug should be taken as follows:
- When treating sore throat in adults, doctors often prescribe Klacid tablets with a dosage of 250 mg. Take 1 tablet twice a day. In this case, it should be washed down with plenty of water, and taken only after meals (after 1 hour). The course of treatment is 5-7 days (depending on the severity of the disease).
- Klacid SR is prescribed in a dosage of 500 mg (1 tablet) once. In case of severe disease or a high risk of complications, the dose of the drug can be doubled and divided into 2 doses - morning and evening. For people with renal failure, the dose of Klacid SR for the treatment of sore throat is halved.
Taking Klacid tablets should be done at intervals of 12 hours (that is, at 7 a.m. and 7 p.m., 8 a.m. – 8 p.m., etc.).
Intravenous infusion of the drug is carried out exclusively in a hospital setting. However, treating a sore throat with a Klacid drip solution is an extreme measure, which is resorted to in extremely severe cases.
Treatment of sinusitis
Klacid for sinusitis is the most commonly prescribed drug, especially if there is purulent contents of the sinuses. To treat this disease in adults, Klacid SR is mainly used - 1 tablet once for 5-10 days. The course of therapy can only be prolonged by an otolaryngologist, but this is often not necessary.
In case of severe purulent sinusitis, the dosage of Klacid SR can be doubled. Moreover, 1000 mg of the drug must be taken at a time. The course of therapy lasts from 6 to 14 days. The Klacida tablet should be taken with meals, avoiding chewing it. After the first dose of the drug, the patient needs to carefully listen to his feelings: if any discomfort occurs, he should contact an otolaryngologist for further recommendations.
To prevent the development of intestinal dysbiosis, probiotics in the form of drops, capsules or dry powder for the preparation of an oral solution should be prescribed along with the antibiotic.
Treatment of otitis media
Klacid is used, as a rule, for otitis media in adults. They use a “pure” drug, without the “CP” prefix, 250-500 mg per day, but in case of severe pathology, the doctor can increase it to 1 g. The dosage is prescribed purely individually, as is the duration of therapy.
Unlike Klacid SR, classic tablets cannot be taken with food. For this reason, you need to wait 1-2 hours after eating before using the drug.
Antibiotics
Now it’s time to take a closer look at the features, functions and effectiveness of those drugs that are prescribed to treat inflammation of the maxillary sinuses. Let's start with the most common group of medications - antibiotics.
Such agents are capable of eliminating infectious agents: staphylococci, streptococci, moraxella, etc. Antibiotics have a wide spectrum of action, since they not only destroy bacteria, but also prevent their reappearance. In addition, the medicine has an antiseptic, antifungal effect, and prevents complications from various infectious diseases.
Doxycycline is a powerful antibiotic that helps with sinusitis.
Here are some antibiotics that deserve special attention:
- Doxycycline for sinusitis. The medicine stops the growth and development of most dangerous microorganisms that occur with sinusitis. Doxycycline is taken for 5-7 days, on the first day you need to take 2 tablets, on all subsequent days 1 tablet is enough.
- Klacid for sinusitis. It is used for bacterial sinusitis; it is also prescribed for bronchitis, pneumonia, tonsillitis, furunculosis, etc. The drug is available in the form of tablets, as well as in the form of granules for the preparation of a suspension. The dosage is prescribed only by a doctor; there are quite a few contraindications. Reviews of Klacida for sinusitis indicate that the product is truly effective, as it helps to get rid of the symptoms of the disease in the shortest possible time. At the same time, do not forget about possible side effects: muscle weakness, skin rashes, nausea, etc.
- Flemoxin Solutab. The medicine relieves inflammation of the sinuses, reduces the duration of the disease, and promotes rapid restoration of the immune system. At the same time, we must not forget that Flemoxin is an antibiotic, and therefore it should be taken only as prescribed by a doctor.
- Macropen for sinusitis. The product perfectly fights intracellular bacteria and is used by both adults and children. Available in the form of tablets and in the form of granules for making a suspension. The course of therapy lasts 7-10 days, you need to take 3 tablets a day: one tablet in the morning, at lunch and in the evening. Judging by real reviews, Macropen for sinusitis affects most pathogens of the disease, thereby promoting a speedy recovery. But if after the prescribed treatment you do not see any improvement, you should contact your specialist again; you may need another medication.
None of the above remedies should be taken independently, without the permission of an otolaryngologist. Antibiotics can stop the inflammatory process and destroy bacteria, but at the same time they can harm the gastrointestinal tract and weaken the functions of the human immune system.
Macropen is a broad-spectrum antibiotic that affects most bacteria
Features of the drug in children
Treatment of otolaryngological pathologies with the antibiotic Klacid should be carried out exclusively under the supervision of a physician. Therapy can be carried out at home, but parents must strictly follow all of its instructions.
Treatment of sore throat
When using Klacid tablets for the treatment of sore throat in children over 12 years of age, adult dosages are used, namely:
- 250 mg of the drug twice a day after meals.
- When using Klacid SR - half a tablet 2 times a day or 1 tablet once a day with meals.
For children under 12 years of age, Klacid is used in the form of an oral suspension. There is no single dosage for all patients, since it is calculated using the formula mg/kg body weight. For this reason, the medication should be prescribed exclusively by an otolaryngologist.
Parents must strictly follow the rules for preparing oral suspension for children.
Treatment of sinusitis
According to the official instructions for use of the drug Klacid, the daily dose for children under 6 years of age is no more than 15 mg of the drug. In this case, the suspension is divided into 2 doses, the interval between which should be at least 12 hours.
For children over 6 years of age, adult doses are used: 250 mg of classic Klacid twice a day or 500 mg of Klacid SR once. In case of severe purulent sinusitis, the dosage of the latter can be increased to 1 g (2 tablets) per dose.
Treatment of otitis media
For otitis media in children, Klacid tablets or suspension are used. The dosage is calculated taking into account body weight, but, as a rule, the generally accepted dose is used - 15 mg per day. The duration of therapy ranges from 6 to 14 days. If even after completing the treatment the desired result cannot be achieved, only the attending physician should take further measures.
Klacid for angina: method of application and dosage
The drug is prescribed when a bacterial infection cannot be treated with penicillin antibiotics, cephalosporins or fluoroquinolones.
Antibiotics should not be taken until a diagnosis is made by a doctor, since their improper use causes microorganisms to become resistant to the drugs.
Antibiotics do not treat viral infections.
It has been established that antibiotic therapy to prevent the development of a bacterial infection during treatment for viruses increases the risk of developing a secondary infection.
Each type of antibiotic is taken at a certain frequency. Violation of the instructions for use will result in a decrease in the effectiveness of the drug.
After three days of taking the medicine, the attending physician determines how effectively the antibiotic copes with the infection. If the effectiveness is low, the drug is replaced.
If side effects occur, it is not always necessary to completely stop taking the medication; sometimes it is enough to adjust its dose.
An underdose of a drug is no less dangerous than an overdose, since there is a high probability of bacteria becoming “accustomed” to the antibiotic.
The frequency of taking the antibiotic should not be violated so that the concentration of the active substance in the body does not decrease.
It is necessary to strictly follow the conditions for taking the medication indicated by the doctor: before, during or after meals.
The peculiarity of macrolides, including Klacida, for angina is that they act somewhat more slowly, since they do not kill microorganisms, but only prevent their reproduction and growth. However, Klacid has an advantage - it is less likely to cause allergies.
Attention
Bacteria can quickly develop resistance to macrolides and Klacid, so the course of treatment with these drugs cannot be repeated earlier than after 3 months.
The course of treatment with Klacid as prescribed by a doctor can be up to 14 days, but depends on the type of disease and the severity of the patient’s health condition. Taking Klacid for a sore throat should last 10 days, and for other infections - from 5 days.
Usually, the drug is prescribed at a dosage of 250 mg every 12 hours or 500 mg once a day. In severe cases, a double dose is recommended: 500 mg twice a day.
Children are prescribed Klacid based on weight: 15-30 mg/kg. For a child weighing less than 8 kg - 7.5 mg/kg.
However, only the doctor prescribes the dosage!
Klacid can be taken with water, juice or milk.
To prepare the suspension, a powder and a bottle are used, in which, after diluting with water, 60 ml of the drug is obtained. 20 ml of suspension is used per dose. Doctors usually prescribe medications in mg, so it is useful to know that 5 ml of Klacida suspension = 125 mg of the drug. Children under 2 years of age are given ½ tsp. twice a day.
The ready-to-use suspension can be stored at room temperature for up to 14 days. Before use, the solution must be shaken to ensure uniform distribution of the antibiotic.
Klacid is taken for sore throat and other bacterial infections, regardless of food intake, but it is important to observe the frequency of administration: 12 hours between doses of the antibiotic.
If the patient cannot swallow tablets or suspension due to health conditions, drip administration of Klacid is prescribed.
Attention
Klacid cannot be used intravenously or intramuscularly, so it is administered within an hour by dropper and only in a hospital under the supervision of medical personnel.
Jet injection leads to inflammation of the vein. After the condition improves, the doctor prescribes the drug in tablet form.
The use of Klacid for a sore throat or for the treatment of other bacterial infections is not always justified, since it should be used only when the disease cannot be treated, for example, Penicillin, Azithromycin, Amoxicillin.
Klacid is a strong drug, so the decision about the advisability of its use should be made by a doctor.
It should be prescribed especially carefully to children, since their immunity is not yet strong enough for the body to accept such a powerful drug. Pediatricians usually prescribe Klacid to children for sore throat with complications, scarlet fever and whooping cough.
An overdose of Klacid can lead to disturbances in the functioning of the central nervous system: mental disorders, which manifest themselves as tearfulness in children, excessive agitation, insomnia, and paranoid syndrome.
Klacid should absolutely not be prescribed during pregnancy, since its effect on the fetus has not been tested in humans, so the drug is prescribed only when the mother’s life is at risk. It is known that the active substance clarithromycin penetrates the walls of the placenta and can cause pathologies in fetal development.
Adverse reactions
If the drug Klacid is used incorrectly or if there is intolerance to its components, the following adverse reactions may occur:
- stomach ache;
- bowel disorders;
- nausea and vomiting;
- taste distortions;
- candidiasis;
- loss of appetite;
- irritability, anxiety, nervousness;
- orientation disorders;
- dizziness;
- skin rash;
- increased sweating, etc.
Even one, the mildest and most insignificant side effect should be grounds for discontinuing Klacid and prescribing another antibiotic.
Prices
Prices for Klacid depend on the dosage of the active ingredient and the form of the drug.
- tablets 250 mg – from 680 rubles;
- tablets 500 mg – within 820 rubles;
- lyophilization for the preparation of solution for intravenous administration (500 mg in 1 bottle) 1 pc. – within 550 rubles;
- Klacid SR (500 mg) – from 1000 rubles;
- powder for the preparation of oral suspension (250 mg/5 ml) in 100 ml bottles (after dilution with water) – within 420 rubles.
Of course, prices may vary depending on the pharmacy network and the region of residence of the patient. Therefore, it is better to ask your doctor about the cost of the drug, so that if necessary, ask to replace Klacid with another medicine.
Despite the fact that Klacid can be used to treat even young children, it is by no means a safe drug. In addition, a large number of side effects should be a good reason for refusing self-medication, and encourage you to seek advice from a qualified doctor.
Author: Elizaveta Krizhanovskaya, doctor, especially for Moylor.ru
What is better for diseases of the lower respiratory tract?
In a study involving 510 patients with acute bronchitis and pneumonia, the following results were obtained: 10 days of clarithromycin (250 mg - 2 times a day) and 3 days of azithromycin (500 mg - 1 time a day) gave a similar therapeutic effect. In laboratory tests for complete bacteriological elimination, Klacid is slightly stronger. In practice, resolution or improvement occurs in 95-100% and both treatment strategies are found to be equally effective.
conclusions
Antibiotics do not belong to medications for self-selection; first of all, a full-time doctor should determine whether Klacid or Sumamed will be better in each specific case. World experience shows that with almost similar effectiveness, Sumamed outperforms its competitor in terms of convenience of regimen and course duration and can be the drug of choice in childhood. Klacid SR, although it allows you to take it once a day, but, like a regular one, requires up to two weeks of therapy.
In terms of the cost of treatment, the Croatian drug is also more profitable and will cost one and a half to two times less.
