Lazolvan or Bromhexine, which is better?

Brief comparison of drugs

ACC is a synthetic cough medicine based on acetylcysteine. The drug stimulates the removal of sputum by thinning the mucus.

Ambroxol is a medicine with a pronounced expectorant effect. The drug also thins mucus and stimulates the elimination of mucus from the bronchi.

The difference between cough remedies lies in the mechanism of action. ACC destroys mucus molecules by destroying disulfide “bridges” that bind mucopolysaccharides in the structure of sputum. Due to this chemical reaction, the viscosity of mucus decreases and its elimination from the bronchi is accelerated.

Ambroxol affects the glands located in the mucous membrane of the respiratory tract. The result is stimulation of the activity of goblet cells with an increase in the liquid component of sputum, which makes the process of its discharge easier. The medication additionally enhances the motor function of the ciliated epithelium of the bronchi. The transport of mucus outward improves with the normalization of microcirculation.

Fact! ACC additionally increases the synthesis of glutathione, a substance with pronounced antitoxic and antioxidant activity. The negative impact of free radicals and secondary drug metabolism products is minimized.

ACC, pros and cons

Cough treatment using ACC alone is less common. The reason is the effect of the product on viscous mucus. If for certain reasons the sputum has not had time to form, the effectiveness of the medicine decreases.

Pros of ACC:

• rapid onset of action – up to 1 hour;
• good liquefaction of sputum, ensuring rapid clearance of mucus from the bronchi;
• interesting dosage form. ACC is available in the form of effervescent tablets that dissolve in water, which accelerates the absorption of the drug into the blood.

The good effectiveness of the drug against the background of a small number of adverse reactions and contraindications makes ACC in demand in the pharmaceutical market.

Negative sides:

• narrow range of indications;
• the need to prescribe additional means for effective cleaning of the respiratory tract. Due to the lack of effect on the cilia of the epithelium, the drug actually has only a mucolytic effect. The rate of elimination of liquefied mucus depends on the individual characteristics of the human respiratory system.

Despite these disadvantages, ACC occupies a place of honor in the treatment of cough accompanied by the formation of thick sputum. Before using the medication, you should consult your doctor.

Ambroxol, pros and cons

Which is better: ACC or Ambroxol? Patients often ask doctors this question. Many people make Ambroxol a competition favorite.

Causes:

1. Large evidence base of the effectiveness of the product. Dozens of clinical studies have proven the feasibility of prescribing Ambroxol for the treatment of coughs of various etiologies;
2. Variability of dosage forms. The drug is sold in tablets, syrups of various concentrations, solutions for inhalation;
3. Safety;
4. "People's" love. Ambroxol is the most commonly prescribed cough medicine.

An important advantage of this cough remedy remains its effect on the alveoli of newborn children. The drug stimulates the synthesis of surfactant, which prevents the respiratory sacs of the lungs from sticking together. This therapy is carried out for premature babies suffering from a lack of the corresponding bioactive substance in the body.

Minuses:

1. The inability to use the medicine in patients suffering from gastric ulcers;
2. The need to select a dose for each age group. Treatment of children under 12 years of age requires the purchase of syrup with a concentration of Ambroxol 15 mg/5 ml, which is not always available in pharmacies;
3. The need to drink large amounts of fluid during treatment to stimulate the function of the bronchial mucous glands.

How are they similar and what is the difference between them

ACC and Ambroxol reach their maximum concentration in the blood simultaneously, within 1-3 hours. The half-life of the drugs is almost the same.

General properties of cough medicines:

• thinning of sputum;
• elimination of predominantly wet cough;
• availability. The price for both medications ranges from 100-120 rubles;
• safety;
• similar contraindications. Medicines should not be taken for gastric or duodenal ulcers due to the risk of worsening the patient's condition.

Differences:

• dosage form;
• mechanism of action.

Which drug is best for children?

Childhood is characterized by frequent respiratory infections, and in some cases, the manifestation of chronic pathologies of the pulmonary system (for example, cystic fibrosis or fibrosing alveolitis). Prospan or Lazolvan is prescribed to a child only if there is thick and difficult to separate sputum. For dry cough, it is not advisable to prescribe these drugs.

The choice between these drugs should be based on the expected effect, the nature of the disease and its very nature. In the treatment of bronchial asthma or severe chronic diseases of the bronchopulmonary system, it is still recommended to use Lazolvan, since it not only thins sputum, but also restores the structure of damaged cells and glands. In addition, the drug is delivered directly to the lungs via the inhalation route.

Prospan has shown its high effectiveness against acute respiratory infections, chronic and acute bronchitis (including obstructive ones). In this case, the effectiveness of the drug is due to its anti-inflammatory and bronchodilator effect. Thus, it is advisable to prescribe an extract from ivy leaves in the case of obstructive bronchitis or ARVI in children suffering from bronchial asthma.

Is it possible to use Ambroxol and ACC at the same time?

Considering the above features, the logical question becomes whether ACC and Ambroxol can be taken together. In 95% of cases the answer is positive. Standards for the treatment of cough accompanied by the formation of thick sputum provide for the simultaneous administration of both drugs.

Good compatibility of the agents and the interaction of bioactive substances, which accelerate the destruction and elimination of mucus, ensure the patient’s recovery with normalization of the function of the bronchial epithelium.

If it is necessary to use antibacterial agents, Ambroxol additionally increases the concentration of antimicrobial agents that penetrate the alveoli, increasing the rate of destruction of pathogenic microorganisms.

The compatibility of Ambroxol and ACC has been proven by clinical studies. The dosage and frequency of administration are selected individually in each case to effectively eliminate cough. The average duration of complex therapy is 1 week.

Important! Independent combination of the described drugs is not recommended due to the risk of adverse reactions. Both drugs negatively affect the function of the gastrointestinal tract.

Which is better: Lazolvan or Gerbion?

Which medicine is better: Lazolvan or Gerbion?
We present the results of the online voting. Answer the question which is better and take part in the battle of two drugs! Don't know which of these drugs is better? Read what people think about it and what reviews they leave about Lazolvan and reviews about Herbion.

Vote! When choosing an answer, we recommend comparing your personal experience of using both Gerbion and Lazolvan: their effectiveness under the same conditions, the presence or absence of side effects of both drugs, and the general impression of their use. Please compare not the cost, but the effect of each medicine. Have your say!

ACC or Ambroxol, which is better for coughs for children and adults

ACC and Ambroxol are not always used together. The choice of the appropriate drug depends on the characteristics of the clinical case, the age of the patient, and the individual characteristics of the body.

Adult patients suffering from a dry, unproductive cough without fever are traditionally prescribed ACC. The reason is the convenient dosage form (effervescent tablets) and the body’s good responsiveness to therapy.

Premature babies are prescribed only Ambroxol. Patients over 2 years of age can take any of the drugs described. If you use Ambroxol, you need to buy syrup at a dose of 15 mg/5 ml.

These situations remain conditional. In each case, the doctor comprehensively assesses the patient’s condition and prescribes the most appropriate drug. Often it is necessary to replace medications due to the nature of the interaction of chemicals with the human body.

Top 10 most popular syrups

The expediency of such ratings is very controversial, because in any case one should not chase fashion and take a medicine depending on the degree of its popularity. On the other hand, such lists indicate a large number of recoveries, which were facilitated by these drugs.

• Prospan
  is a favorite of pediatricians and parents, because it can be used from infancy. It has virtually no contraindications and is equally suitable for children, as well as pregnant and nursing mothers. Good children's cough syrup.
• Gedelix
  is ​​also distinguished by its high content of natural ingredients. In fact, it is a more affordable analogue of Prospan, with minor changes in composition. It is recommended to take Gedelix from the age of six months. It is considered one of the best syrups.

• Lazolvan -
  despite its synthetic composition, this syrup will quickly and most effectively help get rid of a cough. The active ingredient is ambroxol, often used in mucaltic preparations. It has a combined effect and is used to treat children from the age of two (earlier after being prescribed by a pediatrician).
• Bronchipret
  has proven itself to be effective for treating all types of coughs, including wet ones. In some cases, there may be allergic reactions to the active natural components of the drug. Suitable for children from three months of age. An equally effective drug is syrup. The drug successfully fights both dry and wet coughs.
• Eucabal
  is another representative of natural preparations that can be used by children who are already six months old. It has a good expectorant effect and quickly relieves dry and wet cough.
• Alte I syrup
  and its derivatives also enjoy deserved popularity due to their affordable cost and the absence of harmful chemical additives.
• Herbion ivy syrup
  , and both of its other types: with plantain and primrose. It is well suited for a comprehensive effect on all types of cough and has a good herbal composition.
• 
  Judging by the reviews, Sinekod Strong active substances can effectively treat serious conditions and diseases. It has an affordable price and excellent pharmacological characteristics. One of the best and most effective remedies.
• It is also confidently winning the market and the gratitude of parents, because its effectiveness has shown itself well in the treatment of a wide variety of pulmonary diseases.
• rounding out the top ten, which means this syrup has stood the real test of time. Many still remember its characteristic taste, and most importantly, its effectiveness.

The video tells which children's cough syrup is better:

The above list cannot serve as instructions for purchase, because even the same disease occurs purely individually. Of course, each specialist has his own “favorites”, which doctors most often recommend to their patients. If the pediatrician is confident in its effectiveness and has already been convinced of the excellent effect of the drug on the treatment of this disease, his recommendations should be heeded. A qualified doctor will always tell you what syrup is needed. In any case, the thoughtless purchase of any syrup you like cannot be justified, because we are talking about the health and safety of your children. Also read about.

During breathing, the air passing through the respiratory tract is cleaned, moistened and warmed. Foreign particles entering the bronchi settle on their wall. Purification of inhaled air from dust, microorganisms, and harmful substances occurs thanks to special mucus in the bronchi and trachea. Every day, a protective secretion is synthesized in the tracheobronchial tree, which, with the help of ciliated epithelium, removes foreign agents from the body. This process is called mucociliary clearance, and in a healthy person it is the main way of clearing the respiratory tract, and cough is used as an auxiliary mechanism.

In respiratory diseases, viruses or bacteria damage the mucous wall and lead to the development of an inflammatory process. It is during the inflammatory reaction that the synthesis of thick, viscous sputum increases, which is difficult to remove from the bronchi, and the process of physiological cleansing of the respiratory system is disrupted, so coughing becomes the main way to combat this condition. However, such a cough quickly becomes pathological, which requires medication correction.

Features of Lazolvan

Lazolvan is a medicine that is used to treat coughs, colds, and bronchial asthma. Available in the form of a solution for inhalation, tablets, syrup, and alcohol solution. The main component is ambroxol . This substance helps to liquefy thick sputum and simplifies the process of its removal, regulates the functioning of serous and mucosal glands, which affect the thickness of sputum, increases the activity of bronchial cilia, facilitating easy discharge of sputum.

Another undoubted advantage of Lazolvan is that it not only improves the processes of excretion and production of sputum and mucus, but also helps the cells of the bronchi and alveoli to recover . It is often prescribed not only to adults, but also to premature babies who have not developed the required amount of surfactant - a complex of substances that line the surface of the respiratory tract and play a critical role in their functioning.

Contraindications:

1. Allergy to ambroxol.
2. Pregnancy.
3. Lactation period.
4. Lactose intolerance.
5. Kidney failure.
6. Liver failure.

Combination with other drugs:

• Cannot be used with other antitussive medications.
• A number of antibiotics increase the rate of penetration into the respiratory tract.
• Do not combine with drugs that contain cromoglycic acid.
• Other studies have shown that the drug is compatible with most other medications.