Fluimucil for dry cough in children


Compound

1 tablet contains acetylcysteine ​​600 mg and additional substances: sodium bicarbonate, citric acid, lemon flavor, aspartame .
1 bag of granules contains acetylcysteine ​​200 mg, excipients: beta-carotene , aspartame, sorbitol, orange flavor.

1 ml of solution for inhalation and injection contains 100 mg of acetylcysteine , 1 ampoule contains 300 mg of acetylcysteine , additional substances: sodium hydroxide, disodium edetate, water.

Comparison of ACC and Fluimucil

The distinctive features of these drugs are:

  1. Various manufacturers . Some prefer to purchase products from Switzerland and Italy (Fluimucil), while others prefer to purchase products from Slovenia and Germany (ACC).
  2. Release form and dosage of the medicine . This variation allows the drug to be used in different age categories. It’s worth noting right away that ACC wins in this regard, because it is made in the form of syrup, which is very convenient to use for the treatment of respiratory diseases in children. However, pulminologists claim that Fluimucil is produced in the form of a solution for inhalation and injection, which, in principle, is not inferior to ACC, but allows the medicine to instantly reach the right place in the body. It has a particularly important effect in the acute stages of the disease.
  3. Pricing policy in pharmacies . Comparing these two products, it turned out that Fluimucil in the form of effervescent tablets is significantly cheaper than ACC, where the number of tablets for the same dose is 3 times more expensive. Having analyzed the remaining forms, the situation has not changed much. As a result, it turned out that Fluimucil is 10% cheaper in price.
  4. ACC fizzy drinks contain soda ash, but Fluimucil contains baking soda.
  5. Various additives began to be added to ACC more often . This allows you to improve the taste sensation while using the drug. And for patients suffering from diabetes, this medicine is already prohibited for use.
  6. In case of an overdose of ACC, nausea and abdominal pain occur, and even diarrhea is possible, which cannot be said about Fluimucil, where there are simply no side effects.

pharmachologic effect

Has a mucolytic effect. Acetylcysteine ​​breaks disulfide bonds in mucopolysaccharides of sputum, thereby ensuring its dilution and facilitating excretion. Even in the case of purulent sputum, it remains effective.

The drug prevents the adhesion of bacteria to the epithelium of the bronchial mucosa, stimulates cells that synthesize substances that break down fibrin threads. Acetylcysteine the same effect on the secretion of the mucous membranes of the upper respiratory tract.

The drug provides an antioxidant effect, has a cytoprotective effect and neutralizes toxins.

Acetylcysteine ​​has an anti-inflammatory effect due to its ability to suppress the formation of free radicals that cause inflammation in the lung tissue.

Features of ACC

ACC is a medicine aimed at eliminating cough, thinning mucus and promoting its elimination. Available in the form of soluble effervescent tablets, granules, solution for internal administration, syrup.

The main active ingredient is acetylcysteine

. This substance is effectively used to treat diseases that are accompanied by the production of viscous sputum. It is derived from the amino acid natural to the body - cysteine. It can penetrate into the structure of mucus and destroy the bonds between mucopolysaccharides, and this helps to liquefy the mucus.

It is effective not only with ordinary mucus, but also when it contains purulent contents. Acetylcysteine ​​also has an antioxidant effect and helps the body not only get rid of mucus, but also neutralize free radicals that poison the cells of the respiratory tract. The ACC drug is quickly absorbed and excreted by the liver, does not bind to plasma proteins and does not accumulate in the body.

Contraindications:

  1. Intolerance to the main component.
  2. Stomach ulcer.
  3. Gastrointestinal diseases.
  4. Kidney failure.
  5. Liver failure.
  6. Pregnancy.
  7. Lactation period.
  8. Age less than 2 years.

Not compatible with:

  • Other antitussives.
  • Vasodilator drugs: No-spa, Gliofen, Pentamin, Vasobral, Curantil.
  • Antibiotics, since it suppresses their effect, but these drugs can be combined only 4 hours after taking ACC.

Indications for use

  • difficult sputum discharge due to respiratory pathology ( laryngotracheitis , tracheitis, bronchitis , pneumonia , bronchiolitis , lung abscess , fibrosis , bronchiectasis, atelectasis, caused by obstruction of the bronchi with a mucus plug);
  • otitis , sinusitis (catarrhal and purulent);
  • facilitating the release of viscous secretions from the respiratory system (post-traumatic and postoperative conditions);
  • washing of the nasal passages, middle ear, maxillary sinuses, abscesses, fistulas, treatment of the intervention zone during operations on the mastoid process or nasal cavity;
  • preparation for aspiration drainage, bronchography, bronchoscopy.

Fluimucil - instructions for use for the treatment of cough in children, reviews

  • October 14, 2018
  • Pulmonology
  • Savelyeva Victoria

In the process of treating the lungs of adults and children, you can use Fluimucil for cough.
It is an effective drug with the active ingredient acetylcysteine.

Mucolytic medicine thins sputum, makes it easier to separate, prevents serious diseases (pneumonia, inflammation, abscess), and treats bronchi.

Composition of Fluimucil

The medication is presented in the format of effervescent tablets, granules for making a suspension and solution for inhalation or injection. Their composition:

Effervescent tabletsGranulesSolution
DescriptionWhite round tablets with a lemon-sulfur odor, the finished liquid is slightly cloudy, with a lemon flavorWhite-yellow granules with orange speckles, with an orange-sulphurous odorTransparent liquid, upon prolonged contact with air oxidizes to a pink-violet hue
Acetylcysteine ​​concentration, mg600 per 1 piece.100 or 200 per 1 sachet100 per 1 ml (300 per ampoule)
Additional componentsLemon flavor, citric acid, aspartame, sodium bicarbonateSorbitol, orange flavor, aspartame, beta-caroteneWater, disodium edetate, sodium hydroxide
PackageBlisters of 2 or 10 pcs., packs of 1, 2, 5 or 10 blistersPacks of 20 or 30 bags with instructions for useAmpoules of 3 ml, packs of 5 ampoules with a plastic holder

Conditions, shelf life

The drug should be stored at a temperature not exceeding 25°C in a dry place inaccessible to children.

When properly stored, the shelf life of effervescent tablets is 3 years, solution for injection, inhalation - 5 years, solution for oral administration in a closed package - 3 years (after opening - 15 days), granules for preparing a solution - 3 years.

Opened ampoules of fluimucil are stored in the refrigerator for no more than a day.

Fluumucil in tablets and granules is available without a prescription. The solution is according to the recipe.

pharmachologic effect

The mechanism of operation of the product is based on diluting sputum, increasing its volume and facilitating separation.

The sulfhydryl groups of acetylcysteine ​​disrupt the disulfide intermolecular bonds of sputum mucopolysaccharides, depolarize mucoproteins, and reduce the viscosity of bronchial secretions.

The medication is effective against purulent sputum, reduces its secretion, improves drainage and relieves obstruction. The use of the drug leads to a decrease in the adhesion of bacteria on the bronchial mucosa.

Acetylcysteine ​​stimulates mucosal cells that are lysed by fibrin. A similar effect of the substance manifests itself in relation to sputum released during inflammation.

The active substance of the composition penetrates into cells, forms the metabolite L-cysteine, from which glutathione is formed.

This highly reactive intracellular tripeptide has powerful antioxidant and cytoprotective effects, neutralizes endo- and exogenous free radicals.

The use of Fluimucil prevents exhaustion and increases the synthesis of glutathione, which detoxifies harmful substances.

The active component protects the enzyme alpha-antitrypsin (elastase inhibitor) from inactivation of oxidizing agents that produce active phagocytes using the enzyme myeloperoxidase.

Acetylcysteine ​​has an anti-inflammatory effect; it suppresses the production of toxins and oxygen-based active substances that cause inflammation in the epithelium of lung tissue.

Oral forms of the drug are well absorbed in the stomach, reach maximum concentrations after two hours, and have 10% bioavailability.

Acetylcysteine ​​is found in the liver, lungs, kidneys, bronchi, placenta, and binds to plasma proteins by 50%. Metabolism of the substance occurs in the liver, it forms the metabolites cysteine, diacetylcysteine ​​and cystine.

The half-life of the dose is one hour, and in case of liver cirrhosis it increases to eight hours. Residues are excreted in the urine and through the intestines.

Fluimucil - is it an antibiotic or not?

The active substance acetylcysteine ​​is not an antibiotic , so the drug cannot be classified as antibacterial.

There is another form of the drug - Fluimucil antibiotic AT, which contains thiamphenicol glycinate acetylcysteinate and is available in the form of a lyophilisate for the preparation of a parenteral solution.

This drug has a bactericidal effect and should be used with caution.

Pharmacokinetics

When taken orally, it is well absorbed. After administration, the maximum concentration in the blood (15 mmol/l) occurs within 1-3 hours. Bioavailability is 10%.

Penetrates between cells, predominantly distributed in bronchial secretions, kidneys, lungs, and liver. Penetrates through the placenta. Plasma protein binding is 50%. In the liver it is quickly deacetylated to cysteine. In the plasma there is an equilibrium of plasma acetylcysteine ​​and its metabolites (cystine, cysteine, diacetylcystine).

It is excreted in the urine in the form of inactive metabolites, a small part is excreted unchanged through the intestines. The half-life is 1 hour, with liver cirrhosis it increases to 8 hours.

Indications for use

The medicine is used in the treatment of respiratory diseases. The instructions highlight the indications:

  • tracheitis, bronchitis, pneumonia, bronchiolitis;
  • rhinitis, rhinorrhea, sinus congestion;
  • preparation for mastoid surgery;
  • bronchiectasis, abscess or emphysema;
  • cystic fibrosis;
  • laryngotracheitis, pulmonary atelectasis;
  • interstitial lung diseases;
  • sinusitis, sinusitis;
  • purulent, catarrhal otitis;
  • removal of viscous secretions in post-traumatic or postoperative conditions, in preparation for bronchography;
  • rinsing the nasal passages, treating fistulas.
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Source: https://gb4miass74.ru/bolezni/fluimucil-instrukciya.html

» Miscellaneous » For dry cough fluimucil

For the treatment of respiratory diseases or allergic manifestations, Fluimucil for cough has proven itself well.

A person who has a dry cough definitely needs treatment, since the lack of therapy leads to stagnation of mucus in the respiratory tract and leads to the development of an inflammatory process in them.

A dry cough differs from a wet cough in that it is not productive. Thick mucus cannot easily leave the bronchi, lungs, and trachea, which leads to the development of pneumonia or other diseases of the respiratory system.

Fluimucil for cough

What composition and dosage form does Fluimucil have?

The drug is produced in three types:

  1. soluble granules;
  2. effervescent tablets;
  3. solution for injection.

Each dosage form differs in its composition, but each of them contains the unchanged main component acetylcysteine. A packet of granules contains one hundred or two hundred mg, one tablet contains six hundred mg, an ampoule of solution contains three hundred mg.

In addition to acetylcysteine, melicameron contains additional components, such as sodium hydroxide, lemon flavor, sorbitol, water, etc., depending on the type of medicine.

The doctor selects which form to prescribe individually in each specific case.

Pharmacological features

Fluimucil is a mucolytic agent that thins mucus, increasing its volume and promoting separation. This medicine does not lose its effectiveness even when treating cough with purulent sputum. The active substance has an antioxidant and anti-inflammatory effect. Acetylcysteine ​​quickly penetrates cells, catches toxins and neutralizes them.

If you take Fluimucil in tablets and granules, it has accelerated absorption in the human body. The maximum active substance is concentrated in the blood for a maximum of three hours.

The main component of the drug is half eliminated after an hour, but in people with impaired liver function, this can take up to eight hours.

The main component passes through the placenta and accumulates in the amniotic fluid.

Indications for use of Fluimucil

Fluimucil is prescribed during the treatment of diseases of the respiratory system, when mucus is difficult to clear due to its thickness and viscosity. The doctor may prescribe the drug if the patient is diagnosed with one of the following diseases:

bronchial asthma;

In addition, the medicine is prescribed to facilitate the removal of thick sputum after operations.

Rules for treatment with Fluimucil

The method of using Fluimucil to thin sputum directly depends on the form of release of the medication. The granulated medicine is dissolved in two hundred ml of clean water.

  • For newly born children, this form of medication is prescribed 10 mg per kilogram of body weight, only in emergency situations and under the close supervision of a doctor. Formula-fed children take the solution from a bottle. Breastfed babies should take Fluimucil with a teaspoon to prevent breastfeeding.
  • For children aged one to two years, one hundred mg of the drug is given twice a day.
  • Children from two to six years of age are prescribed two hundred ml twice a day or three times one hundred ml.
  • Children over the age of six and adults are recommended to take two or three times two hundred ml.

For an acute illness, Fluimucil for cough is prescribed for an average of one week. Therapy for a chronic disease can take up to two months; the duration of taking Fluimucil is determined by the doctor.

The tablet is dissolved in one third of a glass of clean water and drunk once. As a rule, tablets are prescribed only during the treatment of adult patients. The drug is injected into the deep layers of the gluteal muscle or into a vein.

During the treatment of an adult, three hundred mg of solution is used, the injection is given no more than twice a day. For six to fourteen year old patients, 150 mg of solution is prescribed. Until the age of six, ten mg per kilogram of total weight. The duration of treatment is chosen by the doctor based on the patient’s condition.

With 300 mg of solution, inhalations can be performed for patients of any age group once or twice a day. Endobronchial administration of the drug is also carried out using a bronchoscope or permanent tube. Depending on medical prescriptions, from 300 to 600 ml of Fluimucil per day is injected into the bronchi.

Possible side effect

During therapy with an oral drug, the following may rarely occur:

nasal bleeding

Taking the drug against the background of stomatitis, bronchospasm, and increased blood clotting is dangerous and increases the risk of side effects.

During Fluimucil injections, a rash, hives and a slight burning sensation in the injection area may appear.

Inhalations with this medicine can cause reflex cough, oral stomatitis, inflammation of the nasal sinuses, local irritation of the trachea, and occasionally bronchospasm requiring the administration of bronchodilators.

Who is contraindicated to take Fluimucil?

Cough therapy with this medicine is contraindicated in patients with duodenal ulcers and acute gastric ulcers. Fluimucil should not be used by people who have an individual intolerance to acetylcysteine ​​or any other component of the drug. The drug in tablet form is not used in pediatrics.

Treatment of cough with Fluimucil during pregnancy

If a cough occurs in a pregnant woman, then treatment with Fluimucil should be done as a last resort, when the benefit for the expectant mother is significantly greater than the possible risk for the child. If a woman finds out about her pregnancy while already on treatment, she needs to discuss this with her doctor and, if necessary, change the medication.

If a nursing woman is prescribed Fluimucil, she should stop breastfeeding for the period of treatment, transferring the child to an adapted formula. To maintain lactation, pumping every 3-4 hours is recommended. It is prohibited to give expressed milk to your baby.

Drug compatibility

Fluimucil helps to liquefy and remove mucus, so it cannot be taken in conjunction with medications that suppress cough at the central nervous system level. This can contribute to mucus stagnation in the respiratory system.

The combined use of the drug and nitroglycerin enhances the vasodilatory effect of the latter. Taking ampicillin, tetracycline and amphotericin with antibiotics reduces the effectiveness of both drugs.

The main component of Fluimucil eliminates the toxic effects of paracetamol.

Taking a large dose

In medical practice, no overdose symptoms have been identified when using 500 mg of the main component per kilogram of weight per day. However, you should not deviate from the dose prescribed by your doctor, as this increases the risk of side effects of Fluimucil for cough.

Treatment of cough with Fluimucil

To treat coughs and runny noses with thick, difficult-to-clear sputum, a group of medications called mucolytics are used.

Drugs of this class help to liquefy the viscous secretion and thereby facilitate its removal from the patient’s body.

A well-known representative of this class is Fluimucil, which is used in a complex therapy regimen for rhinitis, tracheitis, bronchitis and other inflammatory diseases of the respiratory tract.

Source: https://ludmilatumanova.ru/raznoe/pri-suhom-kashle-fluimucil.html

Contraindications

  • exacerbation of stomach and duodenal ulcers;
  • individual intolerance to acetylcysteine ;
  • breastfeeding period;
  • for granules - children under two years of age;
  • for effervescent tablets – children and adolescents under 18 years of age.

Children under 2 years of age are allowed to take a solution prepared from granules under the supervision of a doctor for health reasons.

For stomach ulcers, hemoptysis, bronchial asthma , arterial hypertension, pulmonary hemorrhage, phenylketonuria , renal and liver failure, varicose veins of the esophagus, use with caution.

Intravenous administration of the drug to children under 1 year of age is carried out for health reasons, under the supervision of a doctor.

Examples of drugs

Ambroxol

One of the most basic drugs in this series is ambroxol hydrochloride (it is known under such trade names as Ambroxol - produced by the Borshchagovsky plant, Darnitsa, Abrol - a product of the Kusum company, Ambrobene - the German company Teva, Lazolvan - the original Swiss drug and many others). They differ in price and very significantly - for 1 unit of Lazolvan you can buy 3-4 packages of Ukrainian Ambroxol. What a paradox - the quality is quite comparable.

This medicine is available in the form of syrup (for children) and in tablet form (for adults).

The mechanism of action of the drug has different directions. The active substance mainly affects the formation of a large amount of low-viscosity sputum (which can significantly simplify the work of the ciliated cilia of epithelial tissue). This effect is achieved by destroying the disulfide bridges of those substances that make up the secretion of sputum. This mechanism leads to an increase in the effectiveness (productivity) of cough.

An important property of Ambroxol is its ability to enhance the synthesis of surfactant, a substance that helps support the mechanical basis of lung tissue and the alveolar network.

Moreover, due to the medicinal properties of ambroxol hydrochloride, the secretion of surfactant is potentiated in specially designed cells that transit fluids through the alveolar-capillary drainage.

The advantage of this medicine is that under its influence there is no significant increase in the volume of sputum produced.

Treatment regimen: young children are given at the rate of 0.5 teaspoon twice or thrice a day (correlating with the severity of the child’s condition), older children - one teaspoon three times a day, adults and adolescents - one tablet three times a day. In children under 1 year of age, it is better to use ambrobene solution.

Recently, nebulizer therapy has been widely used - the method of inhaling a solution of Lazolvan or Ambrobene, for 5 minutes 3 times a day. A very effective treatment for both children and adults.

An earlier analogue of Ambroxol, Bromhexine, is also an effective drug, but is now produced and sold only in tablet form.

ACC

The next expectorant that has received worthy recognition among doctors and patients is ACC - acetylcysteine. Its treatment mechanism is in many ways similar to Ambroxol, however, this drug has the advantage that it exists not only in the form of tablets and syrup, but also in the form of a sachet. It is easier to dose this medicine than Ambroxol - children should be given a 100 mg packet twice a day, adolescents 200 mg twice a day, adults 600 mg once a day. In addition, there is a tablet form of ACC-long - an effervescent tablet, taken at the rate of 1 per 24 hours (very convenient for a busy person).


The drug should not be given to children under 2 years of age.

You should also take into account that ACC is more expensive than Ambroxol.

A more effective drug - Carbocisteine ​​(Langes) has a more pronounced therapeutic effect and has fewer side effects.

Herbal medicines and dietary supplements

Regarding all other drugs to improve the removal of sputum (meaning herbal origin). Vivid examples are Alteyka, Prospan, Gedelix, Doctor Tais, Mukaltin, Antitussin, Pertussin and others. Despite people's confidence in their safety and effectiveness, the advisability of their use is very much in question.

, and according to many criteria. Even based on the position of currently advertised evidence-based medicine, there is no (scientific) evidence of the effectiveness of these drugs. Not to mention the empirical approach - the difference is at the placebo level, nothing more.

But the worst thing is how large the number of complications that arise after taking this kind of drugs (especially in children). As a rule, these are all kinds of allergic and pseudo-allergic reactions - ranging from angioedema, urticaria and ending with all types of anaphylaxis, Lyell's syndrome).

Side effects

Digestive system: nausea, vomiting, heartburn, heaviness in the stomach, diarrhea .

Allergic reactions: cases of bronchospasm , urticaria , skin itching are possible.

Other symptoms may very rarely include: tinnitus, nosebleeds, collapse.

When used in the form of an aerosol: irritating effect on the respiratory tract, reflex cough, rhinorrhea, rarely - bronchospasm.

Intramuscular administration can lead to urticaria, burning at the injection site, and in case of long-term use, impaired renal and liver function.

Comparison of the safety of Fluimucil and ACC

The safety of a drug includes many factors.

At the same time, in Fluimucil it is quite similar to ACC. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing the metabolism of Fluimucil, as well as ACC, we look at which organ is the metabolizing organ and how critical the effect on it is.

The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Fluimucil does not have any risks when used, just like ACC.

Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Fluimucil and ACC.

Instructions for use of Fluimucil (Method and dosage)

For adults, effervescent tablets are used orally - 1 tablet (600 mg) per day once, pre-dissolved in a third of a glass of water.

The granules are used by both adults and children, dissolved in water (a third of a glass).

Dosage:

  • children over 6 years of age and adults – 600 mg per day in 3 divided doses;
  • for children 2 - 6 years old, 200 mg is prescribed twice a day;
  • 1 - 2 years - 100 mg twice a day.

For newborns, the drug is used under the supervision of a specialist in vital indications, observing a dose of 10 mg/kg of the child’s weight. Children in the first year of life are given syrup to drink from a spoon or bottle.

The average course of treatment is 5-10 days for acute cases, and several months for chronic cases.

For inhalation in physiotherapy, a 10% solution is used in an amount of 3-9 ml. Duration of inhalations is up to 20 minutes, 2 to 4 times a day.

If the drug is used during bronchoscopy for medicinal purposes, use 1-2 ampoules to wash the bronchi.

A dose of up to 300 mg is instilled into the external auditory canal at a time.

For use in rhinitis, there is a special form - nasal drops.

When administered intravenously (drip or slow stream) or intramuscularly, doses are determined as follows:

  • adults - 300 mg up to 2 times a day;
  • children 6-14 years old, 150 mg 2 times a day;
  • children under 6 years old - at the rate of 10 mg/kg.

Acetylcysteine to children under 1 year of age in hospital settings for health reasons.

The duration of treatment depends on the patient's condition.

When used for cough in children under 6 years of age, preference should be given to oral administration.

For intravenous administration, the drug is diluted with 0.9% sodium chloride solution in equal quantities. The duration of treatment in case of intravenous administration should not exceed 10 days.

In elderly patients, the instructions for Fluimucil indicate the need to use the minimum effective doses.

Fluimucil and ACC - what is the difference?

Acetylcysteine

is the main active ingredient in both drugs, so we can rightly say that ACC is an analogue of Fluimucil in composition. The high effectiveness of acetylcysteine ​​has been confirmed by numerous studies. Its action is aimed first at improving the productivity of cough (this occurs already on the 1-2 day of use), and then getting rid of it. For this reason, you should not take medications that suppress the cough reflex at the same time. In addition to a pronounced mucolytic effect, the substance has antitoxic and antioxidant properties.

Both drugs are imported: Fluimucil is produced in Italy or Switzerland, and ACC in Germany or Slovenia.

Release forms and their diversity are where Fluimucil clearly differs from ACC.
Both drugs are presented in various variations, allowing their use depending on age and method of delivery to the body. To make it easier to navigate, let’s imagine the difference between their rulers in the form of a table. The difference is in the release forms of Fluimucil and ACC. The amount of acetylcysteine ​​is indicated in milligrams.

FluimucilACC
Effervescent tablets:
600 mg each - 10 or 20 pcs.100 mg - 20 pieces (for children), 200 mg - 20 pieces, 600 mg (ACC Long) - 10 or 20 pieces
Granules for preparing the solution:
200 mg each - 20 sachets100 mg each - 20 sachets (orange flavor for children), 200 mg each - 20 sachets (orange flavor), 200 mg each - 20 sachets (for preparing a hot drink, orange flavor), 200 mg each - 20 sachets (for preparing . hot drink, taste of honey and lemon)
Syrup for children:
100 ml bottles (20 mg per 1 ml)
Oral solution:
200 ml bottles (40 mg per 1 ml)
Solution for inhalation and injection:
5 ampoules of 3 ml (100 mg in 1 ml)

The table shows that ACC has a larger range of release forms and flavors than Fluimucil. All forms of ACC except syrup are available in different doses of acetylcysteine, tastes and even temperatures of the finished drink. This allows you to calculate the dosage more flexibly, which is especially important in childhood (you can give not only syrup, but also effervescent tablets or granules of 100 mg). It is more convenient for adults to manage the number of doses per day, for example, you can take 200 mg tablets 3 times a day, or you can take ACC Long, which contains the daily norm of acetylcysteine, just once a day. On the contrary, Fluimucil effervescent tablets are available only in a high dose, designed for one dose.

However, Fluimucil has a very important advantage - it is produced in ampoules, the solution from which is also used for inhalation. Naturally, the shorter and more natural method of delivery to the respiratory tract has a positive effect on its speed of action and effectiveness compared to oral forms. This is especially true in acute conditions.

Interaction

Combined use with cough suppressants that suppress the cough reflex contributes to stagnation of sputum.

The use of tetracyclines (except doxycycline ), amphotericin and ampicillin leads to a decrease in the effect of both antibiotics and acetylcysteine , so the break between taking these groups of drugs should be at least 2 hours.

The antiplatelet and vasodilating effect of nitroglycerin is enhanced when taken simultaneously with Fluimucil.

Acetylcysteine ​​can reduce the toxic effect of paracetamol on the liver.

Pharmaceutically incompatible with other medicinal solutions.

Brief comparison of drugs

ACC is a synthetic cough medicine based on acetylcysteine. The drug stimulates the removal of sputum by thinning the mucus.

Ambroxol is a medicine with a pronounced expectorant effect. The drug also thins mucus and stimulates the elimination of mucus from the bronchi.

The difference between cough remedies lies in the mechanism of action. ACC destroys mucus molecules by destroying disulfide “bridges” that bind mucopolysaccharides in the structure of sputum. Due to this chemical reaction, the viscosity of mucus decreases and its elimination from the bronchi is accelerated.

special instructions

Fluimucil is prescribed to patients with bronchial asthma and obstructive bronchitis with caution and under constant monitoring of bronchial patency.

It is not recommended for use in patients with phenylketonuria , since the drug contains aspartame .

For dissolution, use only glass containers and avoid contact with rubber and metal surfaces.

The smell of sulfur that appears when opening a bag of granules is a normal odor characteristic of the active substance.

Analogs

Level 4 ATX code matches:
Mukolik

Abrol

Ambrosan

Bronchorus

ACC 100

ACC 200

ACC Long

ACC

Mukolwan

Lazolvan

Bromhexine 8

Bromhexine 8 Berlin-Chemie

Bromhexine

Bronchobos

Carbocisteine

Erdomed

Pulmozyme

Pectolvan C

Halixol

Ambrobene

ACC , Vicks-active Expectomed

Fluimucil or ACC - which is better?

Both drugs contain the same active ingredient. They differ only in manufacturer and price, and even then only slightly. For example, 6 sachets of ACC with a dose of 600 mg cost 127 rubles, and Fluimucil costs 10 tablets. 174 rub. Therefore, the buyer must decide for himself which drug to choose.

What is better for children - ACC and Fluimucil?

Both drugs are contraindicated in children under two years of age. The correct selection of the amount in each specific case should be carried out by a pediatrician; the recommended dosages of acetylcysteine, which should not be exceeded regardless of the release form of Fluimucil or ACC, are as follows:

  • from 2 to 6 years - 2-3 times a day, 100 mg (total 200-300 mg per day);
  • from 6 to 14 years - 3 times a day, 100 mg or 2 times 200 mg (total 300-400 mg per day);
  • over 14 years old - 2-3 times a day, 200 mg (total 400-600 mg per day).

In general, although ACC and Fluimucil are the same thing, the former offers a greater variety of medicine types and flavors for young children, including cherry syrup, which comes with a measuring device (syringe or measuring cap) in the package, allowing dose the medicine correctly.

Drinking plenty of fluids is one of the keys to the success of treatment with acetylcysteine-based mucolytics. Alkaline mineral waters help them best with this. Also, to increase the effectiveness of therapy, it is desirable to maintain optimal air humidity in the room.

What is the difference in contraindications and price between Fluimucil and ACC?

Both mucolytics are contraindicated in case of hypersensitivity to acetylcysteine ​​or auxiliary components; up to two years of age (up to 14 years in 600 mg tablets), pregnant and lactating women (in special cases, strictly under the supervision of a doctor); for certain forms of ACC: fructose intolerance, glucose-galactose deficiency.

As for the question of choosing Fluimucil or ACC - which is better to buy, the situation here is ambiguous. In almost all similar forms of release, Fluimucil will be only slightly cheaper than its opponent. But for a package of 10 effervescent tablets of 600 mg - Fluimucil or ACC Long, the former will cost almost half as much. Most likely, such a significant difference is associated with the country of production, because in the same dosage (600 mg), but in packages of 20 tablets, these drugs cost almost the same. Thus, if you need long-acting effervescent tablets for adults, it is more profitable to take Fluimucil in 10 pieces; in other cases, the price difference is insignificant.

Reviews of Fluimucil

Fluimucil is quite popular for use against coughs. Numerous reviews are usually positive. There are good results from use against cough - Fluimucil is quite effective in both adults and children. On forums for young mothers, when asked to recommend a good cough syrup, many people remember Fluimucil. Perhaps the only drawback of using the drug is the formation of a large amount of sputum.

Nasal drops are also popular - there are many positive reviews when used in case of rhinitis.

Fluimucil price, where to buy

In Russia, the average price of Fluimucil tablets is 200 rubles. In Moscow, a package of 10 tablets with a dose of 600 mg costs 174 rubles, and granules can be bought for 186 rubles. for 20 packages.

  • Online pharmacies in RussiaRussia
  • Online pharmacies in KazakhstanKazakhstan

ZdravCity

  • Fluimucil granules for intravenous solution.
    approx. orange 200 mg 20 pcs. Zambon Switzerland Ltd. 105 rub. order
  • Fluimucil tablets spike. 600 mg 10 pcs. Zambon Switzerland Ltd.

    RUB 144 order

  • Fluimucil tablets spike. 600 mg 20 pcs. Zambon Switzerland Ltd.

    RUR 469 order

  • Fluimucil solution for internal use. approx. 20mg/ml 100mlZambon S.P.A.

    RUB 176 order

  • Fluimucil solution d/in. and ingal. 100mg/ml 3ml n5Zambon

    220 rub. order

Pharmacy Dialogue

  • Fluimucil ampoules 300mg/3ml No. 5Zambon

    RUB 219 order

  • Fluimucil-antibiotic IT (vial 500 mg No. 3 + solution) Zambon

    RUR 725 order

  • Rinofluimucil (spray 10ml)Zambon

    RUB 287 order

  • Fluimucil (tab.spike.600mg No.20)Zambon

    472 RUR order

  • Fluimucil (tab. spike 600 mg No. 10)Zambon

    147 RUR order

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Antibiotic Fluimucil IT for inhalation

The drug has no analogues in the complex treatment of respiratory diseases, because it simultaneously has an antimicrobial and expectorant effect. Carrying out inhalations using a nebulizer helps deliver the drug in finely dispersed form to the problem area. Antibiotic Fluimucil IT:

  • acts locally;
  • penetrates deeply;
  • moisturizes the mucous membrane;
  • thins mucus;
  • simplifies its removal;
  • improves sputum secretion;
  • promotes expectoration;
  • cleanses the bronchi;
  • acts anti-inflammatory.

Often, to solve problems of the nasal cavity, Rinofluimucil spray is used, which has an anti-inflammatory effect. If the cause of the disease is viruses, and the respiratory tract disease is accompanied by a cough, the antibiotic Fluimucil IT is prescribed for inhalation. Thanks to its local effect, it does not harm the entire body. With the help of medicine, drainage in tuberculosis is improved. It is used to prevent complications after operations. Diseases treated with antibiotics:

  • bronchitis;
  • pneumonia;
  • tracheitis;
  • cystic fibrosis;
  • broncholitis;
  • sinusitis;
  • sinusitis;
  • otitis.

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Composition of the medicine

Fluimucil-antibiotic IT for inhalation is a complex combination product that has an active ingredient - thiamphenicol glycinate acetylcysteinate. It is produced in the form of a lyophilisate - a powder of a special preparation technology. The kit consists of an ampoule with an active substance that has a sulfurous odor, dosage of 250 ml, 500 ml. To dilute the antibiotic, the package contains special bottles of water.

Pharmacology of the active components of the drug

Each of the main active components of Fluimucil-antibiotic IT for inhalation is aimed at solving its own problems. The substance thiamphenicol is not used independently, in its pure form. It prevents the proliferation of harmful microorganisms by blocking protein synthesis in cell walls. Acts on different types of bacteria:

  • E. coli;
  • staphylococci;
  • hemophilus influenzae;
  • pneumoniae streptococcus;
  • corynebacteria.

Another component that is included in Fluimucil-antibiotic IT for inhalation is acetylcysteine, a strong expectorant that helps thiamphenicol penetrate into tissues. With his help:

  • the ability of bacteria to attach to the mucous membrane decreases;
  • the proliferation of microorganisms is inhibited;
  • sputum thins;
  • its separation and removal is facilitated.

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