Recently, pediatric otolaryngologists have increasingly prescribed the nasal drug “Polydexa” (with phenylephrine) in a conservative therapeutic treatment plan. This applies to specific nasal inflamed adenoids in the nasopharynx in children , as well as to adenoid invasion affecting other tonsillar organs (ears - with otitis, pathogenesis of the salivary glands - sialadenitis, larynx - with laryngitis, tonsillitis). The feedback that the doctor supervising the child’s treatment receives from parents is the most encouraging.
The medication, “Polydex” for adenoids in children , according to reviews from both parents and clinicians, is indeed effective, fast and reliable.
But its use requires an extremely responsible attitude in terms of dosage, frequent use and restrictions to the age group of children suffering from adenoid intoxication. This requirement is based on the fact that this universal medicine is a potent hormonal antibiotic.
Differences between Nasonex and Polydex
The differences between the drugs are that Polydexa is a complex drug that has both anti-inflammatory and antibacterial properties, while Nasonex has anti-inflammatory and antiallergic effects.
Polydex contains the following active ingredients:
- polymyxin B sulfate;
- dexamethasone sodium metasulfobenzoate;
- phenylephrine hydrochloride;
- neomycin sulfate.
Polydexa is a complex remedy that has both anti-inflammatory and antibacterial properties.
Additional substances:
- Lithium chloride.
- Methyl parahydroxybenzoate.
- Lemon acid.
- Macrogol 400.
- Lithium hydroxide.
- Polysorbate
- Purified water.
The presence of phenylephrine in combination with dexamethasone provides the drug with anti-inflammatory properties. Phenylephrine has a vasoconstrictor effect on the vessels of the nasal mucosa.
The antibiotics niomycin and polymyxin B, present in the drug, have an antibacterial effect. The combination of several antibiotics makes it possible to expand the range of use of the drug. A nasal spray with an antibiotic can act on most gram-positive and gram-negative pathological microorganisms that can provoke inflammatory processes in the nasal cavity and paranasal sinuses.
The main active ingredient of Nasonex is mometasone furoate.
Excipients:
- dispersed cellulose (sodium carboxymethylcellulose and MCC);
- glycerol;
- lemon acid;
- polysorbate-80;
- sodium citrate dihydrate;
- benzalkonium chloride solution;
- purified water.
Mometasone furoate provides the drug with anti-inflammatory and antiallergic properties.
The active compound of the spray is a synthetic corticosteroid intended for topical use, so Nasonex is a hormonal medication.
Chemical and pharmacological composition of "Polidex"
In order to shoot intensively, literally before your eyes:
- Pathological congestion, swelling of the nasal mucous surfaces;
- Almost completely remove the symptoms of a runny nose;
- Stop all types of cough (dry, wet);
- Stop purulent discharge of infected mucus from adenoid focal locations;
- Absolutely destroy the main causative agents of adenoiditis (pseudomonas aeruginosa, meningo/staphylococcus/streptococcus aureus) - the drug is equipped with an extremely effective antibiotic, antioxidant, hormonal list.
100 ml of ready-made pharmacological modem contains:
"Neomycin" (antibiotic):
The amount of substance in the medicine is 1g (in one gram there are 650,000 units!)
Articles on the topic “Lymphomyosot”: instructions for use for children with adenoids
_________________________________________________________________
"Polymyxin" (antibiotic)
– in 1 g (1,000,000 units!)
_________________________________________________________________
"Dexamethasone" (synthetic corticosteroid hormonal ingredient) -
includes 25 mg!
_________________________________________________________________
"Phenylephrine", "Thimerosal", "Sodium Hydroxite",
These are the most effective antioxidants and adrenergic agonists! Each is presented at least 10 mg!
______________________________________________________________________
In addition to these dominants, the drug "Polydex" for adenoids in children contains an impressive list of auxiliary components.
- Lithium chloride and lithium hydroxide;
- Methyl parahydroxybenzoate;
- Macrogol;
- Polysorbate;
- Lemon acid.
Of course, they are all sufficiently diluted with distilled water, which significantly reduces their concentration, according to microbiologists . But, nevertheless, the drug belongs to the category of pharmacological agents, the use of which is carried out only under the supervision of a doctor!
Indications for simultaneous use
Allergic rhinitis with secondary infection, adenoiditis.
Viral or fungal infection of the nasal mucosa (ARVI, candidiasis), intolerance to components, closed-angle glaucoma, pregnancy, lactation, age up to 2.5 years, use of MAOIs.
When prescribing sprays for therapeutic measures, one should take into account the possible presence of contraindications for use in the patient.
Nasonex should not be used if active or latent forms of tuberculosis infection of the respiratory tract have been identified.
The main contraindications to the use of Nasonex are:
- individual intolerance to any of the components included in the drug;
- the patient has an untreated or undertreated local infection, provided that the nasal mucosa is involved in the pathological process;
- identified active or latent form of tuberculosis infection of the respiratory tract;
- untreated infection of a bacterial, viral or mycotic form, as well as an infectious process provoked by the herpes simplex virus that affects the eyes.
In case of recent injury to the nose or surgical intervention on the organ, the use of the drug is prohibited until the wounds have completely healed.
For Polydex there are the following contraindications for use:
- The presence of high sensitivity to its components.
- If there is a suspicion of angle-closure glaucoma.
- In case of using MAO inhibitors.
- When identifying kidney diseases in which albuminuria occurs.
It is recommended to prescribe the drug with caution if the patient has signs of the development of hyperthyroidism, hypertension, angina pectoris and ischemic heart disease.
Cost and analogues
The cost of the drug ranges from 250-280 rubles. Medicinal sprays with similar effects are the following:
- Bioparox - spray for the nose and throat. The active ingredient is the local antibiotic fusafungin. Price about 510-530 rubles;
- Polydex with phenylephrine. A nasal spray containing the local antibiotics Polymyxin B and Neomycin, as well as the hormone Dexamethasone and the vasoconstrictor component Phenylephrine. Cost 320-350 rubles.
Important! Before using Isofra or similar drugs in children with adenoiditis, you should first consult a specialist.
Is it possible to take Nasonex and Polydex at the same time?
Polydexa can be used in conjunction with Nasonex, but only in severe situations when the use of other means does not give the desired positive effect.
The doctor prescribes complex treatment with both drugs in the following cases:
- When severe forms of seasonal or year-round rhinitis occur with the addition of a bacterial infection.
- With the development of sinusitis, nasopharyngitis or sinusitis in acute or chronic form, but only if bacterial infection is associated with the underlying disease.
- In some cases with adenoids.
It is not recommended to use these drugs in combination when identifying a cold caused by a viral infection, which the active components of Polydex and Nasonex are not able to influence.
Medications are prescribed in short courses so as not to provoke addiction and side effects.
Rules of application
Isofra irrigation spray is used strictly according to the indications of an ENT doctor, who determines the duration and dosage of treatment for the patient.
For adults, daily irrigation of the nasal mucosa is prescribed five times (one injection into each nasal passage).
For children, the following dosage is prescribed: daily three injections into each nostril.
The standard course of treatment is ten days. If use for a week does not show positive dynamics in treatment, the doctor discontinues the drug.
Side effects
In the case of treatment with Polydex, side effects may occur such as a feeling of dryness in the nasal cavity and allergic reactions in the form of itching, skin rashes and urticaria.
Long-term use of the drug can provoke the appearance of systemic side effects in the form of headache, tremor, tachycardia, blanching of the skin, increased blood pressure and insomnia.
When treating allergic rhinitis, the following may occur:
- pharyngitis;
- nosebleeds;
- irritation of the mucous membrane in the nasal cavity;
- burning sensation in the nose.
When treating allergic rhinitis in children, the following may occur:
- Nosebleeds.
- Irritation of the nasal mucosa.
- Headache.
- Sneezing.
When treating sinusitis, the following may be recorded:
- pharyngitis;
- headache;
- irritation and burning sensation in the nasal cavity.
Very rarely, ocular hypertension or perforation of the nasal septum may occur.
Irritation of the mucous membrane, sneezing, increased intraocular pressure, allergies.
Tips and reviews that are useful in relation to “Polydex” for adenoids in children
Children's specialists in the field of general pediatrics and clinics for children's adenoid vegetations warn parents - be careful and responsible in treating children with Polydexa (at home). At the slightest suspicious manifestation of pathogenic symptoms after taking the drug:
- Sudden weakness in a child;
- Dizziness;
- Vomit;
- Blue discoloration around the lips and nose;
- Rapid breathing, palpitations - stop giving this medication to your child.
It is possible that the child’s individual tolerance does not perceive any component and reacts with symptoms of drug incompatibility. Although, before prescribing, the doctor usually conducts an allergen test for an antibiotic, hormone, and related chemical microelements. To prevent the situation from repeating itself, here's an example:
Review from mom: (Maria K., Kaliningrad). I am 30 years old. I, along with my 7-year-old son (I am raising him alone), found myself in a very unpleasant situation with Polydex. My Vadik was diagnosed with stage 2 adenoids in his nose. I treated him with everything! A “mom” I knew recommended “Polydex” for adenoids, saying that it completely cured her daughter’s entire illness, there was not even a trace of it. I, without the advice of a pediatrician or ENT doctor, bought the drug (how is it still sold so freely in pharmacies!), and began to treat Vadim myself. God, what happened to him! The temperature rose, vomiting began, the son turned pale and began to choke. I had to call an ambulance. Well, I got it from the doctor who came to the call! It turns out that I gave my son an increased dose of the drug and did not look at the labeling on the box. Without the consent of the attending physician! The drug is truly wonderful and effective, the ambulance doctor spoke about this. But you can’t use a child with the strongest hormonal antibiotic so thoughtlessly! Be careful, moms.
Related articles Newfangled drug “Nasonex”: pros and cons for adenoids in children
PS And I cured my son’s adenoids, namely, with Polydexa. But, already under the supervision of a doctor, with precise dosage and administration. Great medicine!
Reviews from doctors
Most doctors leave positive reviews about the use of drugs.
Sheremetyeva A.V. therapist, 14 years of experience, Volgodonsk
Polydexa and Nasonex are good, time-tested drugs. When used correctly, it quickly relieves the symptoms of pathology, including chronic sinusitis. Well tolerated by children.
Samoshina T. S. pediatrician, 10 years of experience, Ekaterinburg
Good drugs. When they are prescribed, positive dynamics are not long in coming. The nature of discharge from the nasal cavity changes already on the second day of treatment. The medications are well tolerated by both adults and children, but in some cases an allergic reaction has occurred when the medications were prescribed.
Goryaeva E.S., allergist
I prescribe a nasal spray for children for allergic rhinitis - hay fever. This reaction often causes an infection to develop, so an antibiotic spray is the best choice.
Stasova A.N., ENT
I prescribe the spray to people with adenoiditis, rhinitis caused by seasonal allergies. Helps quickly.
Active components of the drug and proper use
The main active ingredient of this drug is framycetin, which is an antibiotic. In its form, Isofra is a spray or nasal drops.
This remedy differs from others in that the antibiotic included in its composition is used against those microbes that are not sensitive to penicillin - Klebsiella, Proteus, staphylococci and others.
Isofra is dripped or sprayed into the child’s nose. This should be done only after the nasal passages have been cleared. Usually, parents wash the baby's nose before using Isofra. Children are recommended to spray the drug into the nose once a day, that is, the child receives a dose in each nostril in the amount that is formed with one press. The duration of treatment is 10 days.
As is known, in children and especially in infants, the use of oral antibiotics is often associated with a number of difficulties.
Here we can mention the imperfection of the digestive tract, a persistent violation of the microbiological balance, which occurs everywhere in children, and this is not to mention the numerous allergic reactions to drug components.
In such cases, local use of an antibiotic is the most appropriate solution. The manufacturer himself advises using Isofra starting from the child’s first year of life, however, the practice of using the drug shows the success of its use even in one-month-old infants. When using the product, an extremely small amount of antibiotic enters the baby’s blood, which is the optimal solution.
Of course, you should not use this drug at the first signs of a cold. It is usually prescribed in cases where the runny nose has become protracted and purulent discharge from the nose is observed. Very often, Isofra helps in cases of sinusitis, rhinitis, inflammation of the tonsils and adenoids.
With enlarged adenoids in children, parents are faced with the problem of their treatment. Most topical medications must be dissolved so that the active components reach the back of the mouth. It is very difficult to explain such subtleties of treatment to a child, especially a small one.
In such situations, Isofra is a real savior. Despite the fact that it is used nasally, the composition gradually flows down the pharynx, lingering there for some time. In addition, the treatment of adenoids must be comprehensive, and the drugs must effectively act on both microbes in the oral cavity and microorganisms contained in the upper respiratory tract.
Isofra shows excellent results here too, because the antibiotic framycetin is a broad-spectrum active substance. Clinical studies have proven that already on the 2-3rd day of using this drug, the babies’ condition improved and their breathing was restored. On the tenth day from the start of using Isofra, some patients were able to completely get rid of cold symptoms without a trace. In the remaining patients, the severity of the disease decreased.
When using this drug, it is especially important to follow all the recommendations described in the instructions for use. Without rinsing or cleansing the nose, treatment with Isofra may be almost useless.
Another point that parents should remember is the need to complete the course of using the drug, even if all the symptoms of the disease have passed.
Bacteria and microbes that are located in the pharyngeal tonsil are very difficult to remove. The disappearance of signs only indicates a decrease in the activity of microorganisms, but not their complete removal. Otherwise, parents risk getting inflammation in their baby, which will already be resistant to many drugs, and even Isofra will be useless.
It is worth remembering that Isofra can only be used on the recommendation of a doctor, and certainly not to start treating a runny nose that has just appeared. The use of antihistamines in conjunction with this drug often increases the effectiveness of therapy.
Source: o-bolezni.com
Features of use for children
The spray is approved for use by children from 2.5 years old.
p, blockquote 9,0,0,0,0 —>
How to drip Polydex into the nose of children:
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- before use, the nose must be cleared of mucus: drop drops based on sea water or a 2% soda solution and blow your nose thoroughly;
- in accordance with the instructions, up to 15 years of age, the spray is used one injection 3 times a day;
- course of treatment – up to 10 days.
How often can the spray be used? It is prescribed only by a doctor - an otolaryngologist or pediatrician - in courses and strictly according to indications. The spray is not used for the throat.
p, blockquote 11,0,0,0,0 —>
Scheme for using Isofra for adenoids
The antibiotic "Isofra" is prescribed to children for adenoids and other diseases of the ENT organs. To achieve a therapeutic effect, it is enough to make a single injection three times a day. This treatment regimen must be followed for 7-10 days.
If the child’s condition does not improve 3-4 days after starting the drug, it may need to be replaced. The option of additional inclusion of an agent that belongs to the group of systemic antibiotics is also being considered.
The spray does not cause any problems in application. Before starting the procedure, you need to pick up the bottle, shake it, and then make one injection into the nostril. At this time, it should be placed in an upright position.
It is necessary to start rinsing the nose after its cavities have been thoroughly cleaned. To do this, it is advisable to wash the organ. This is a mandatory procedure that will prepare the affected area for treatment. Otherwise, the therapy will not have a positive result, since the active substance of the drug will not reach the source of inflammation.
It is necessary to remember the following points regarding treatment with Isofra:
- For a sick child with adenoids, it is enough to inject only 1 dose of the drug three times a day.
- Adults need to inject the medicine in the amount of 1 dose about 4-6 times a day.
- Spray-based therapy lasts no more than 10 days. It is undesirable to exceed the permissible duration of treatment, as this may lead to negative reactions.
Compliance with the basic requirements allows you to achieve high effectiveness of treatment with the Isofra antibiotic. The child’s attending physician should warn the child’s parents about this. If the drug is used in the wrong dosage, this can lead to low effectiveness of therapy.
Polydexa or Nasonex which is better for adenoids. Polydexa and Nasonex together
Treatment was prescribed: Sinupret for 14 days, Polydex with phenylephrine for 10 days. There was no temperature, no antibiotics were prescribed. Cured. It's now 15.09.
10 again purulent discharge from the nose, loss of smell and taste, polydex dripped again. I rinse my nose with furatsilin. I don’t know what to do anymore, it’s just a cry from the heart.
I've heard about Nasonex spray, is it possible to use it simultaneously with Polydex? How often can you use Polydex? What can you recommend about Nasonex?
Thank you very much in advance.
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Polydexa or Nasonex: combined and separate use
It happens that a cold or allergic runny nose is complicated by a bacterial infection, develops into sinusitis or sinusitis, and curing it is not so easy. Some of the drugs that can help cope with such ENT diseases are Nasonex and Polydexa.
How do they work?
In severe forms of respiratory tract diseases, especially those complicated by an associated bacterial infection, antibiotics and drugs that relieve inflammation cannot be avoided. Therefore, ENT doctors quite often resort to local nasal sprays. The advantages of such medicines are:
- A quick effect that develops almost immediately as the drug enters the nasal mucosa.
- Almost complete absence of a general effect on the body, and therefore most of the side effects that drugs for oral administration, especially antibiotics, have.
- Pronounced and rapid local action, which allows the use of such drugs even in the youngest patients, starting from two to three years of age.
Despite the similarity of treatment effects and indications for use, Polydex and Nasonex differ in composition and mechanism of action.
Polydexa
It is a combination drug that contains several medicinal substances:
- Neomycin is an antibiotic from the group of aminoglycosides, has a bactericidal effect, that is, it causes cell death, disrupting important synthesis processes in it, in particular protein synthesis.
- Phenylephrine is a substance that causes constriction of blood vessels, including small ones, facilitating breathing and relieving swelling.
- Polymyxin is another antibiotic, only from the group of polypeptides. It differs in that, by attaching to the membranes of bacterial cells, it causes their destruction, that is, it also belongs to bactericidal agents.
- Dexamethasone is a synthetic glucocorticosteroid, that is, a substance similar in its structure and effect on hormones that are normally produced in the human body, in particular by the adrenal cortex. Relieves itching, irritation and inflammation.
Thanks to this composition, Polydex for the nose has the ability to relieve inflammation, facilitate breathing and kill bacteria that cause an infectious disease.
Polydexa comes in two dosage forms: nasal spray and ear drops. Unlike the first drug, the drops do not contain phenylephrine and have a lower concentration of dexamethasone. You cannot replace one medicine with another.
Nasonex
Nasonex contains only one substance - mometasone fuorate. Like dexamethasone in Polydex, it is a synthetic glucocorticosteroid. It has pronounced anti-inflammatory and antiallergic effects and, when applied topically, has virtually no general effect.
The main mechanism for the development of the therapeutic effect is the inhibition of various inflammatory mediators - substances that are produced in the body in response to the penetration of bacteria, viruses or allergens and cause the development of the disease.
In addition, Nasonex helps special cells of the immune system - neutrophils - accumulate at the site of infection and thereby also blocks its spread.
Despite the fact that Nasonex is considered one of the safest glucocorticoid drugs, it is available by prescription and should only be used as prescribed by a doctor.
Concomitant use
Can Polydexa and Nasonex be used simultaneously? Yes, for some diseases these medications are indeed prescribed together. However, they are used only in difficult situations when other means have not had the desired effect. So, your doctor may prescribe the following combination for you or your child:
- For severe seasonal or year-round rhinitis, especially with associated bacterial infection.
- For sinusitis, nasopharyngitis or sinusitis, both acute and chronic, but only in the presence of a bacterial infection.
- In some cases with adenoids.
You should not use these remedies for a common cold, since it is often caused by viruses, which neither Polydexa nor Nasonex have an effect on. Usually the drugs are prescribed in short courses and do not cause addiction or unpleasant side effects.
Polydexa and Nasonex together
BUT the fact is that we used it for 6 months + Erius.
The fact is that the child often caught a cold - he had a long runny nose for more than 2 months) - at that time we were 1.8 years old - but the snot did not flow, and did not breathe, he snored terribly at night, somewhere inside he was gurgling . The ENT specialist at the regional hospital (in Murmansk) said that we should wait until 3 years - and at 3 years old, check for adenoids. Until then, this is its purpose.
A month later he began to breathe normally, and was not sick for six months. Stopped - all over again.
Now we are 2.7. I caught a cold again (although we went to the garden). I don’t know what to do - probably go to ENT specialists again - but we don’t have any good ones (can you imagine, in our children’s school a former traumatologist-orthopedic surgeon now works as an ENT specialist - there was no traumatologist’s appointment for her, so she retrained in three months - and oops - ENT)
And we have already been checked for adenoids. They said that adenoids are grade 1 or 2 - in general, nothing to worry about. And the runny nose is constant, sometimes less and sometimes more. He is sick all the time in kindergarten.
Mom_Galya, you were addicted, right?
But I really don’t want to give hormones at 4.5 years old, and we don’t have a “scary” picture, it’s just that, due to the adenoids, for several months now the nose has been regularly stuffed up in the morning or at night, so he doesn’t sleep well. During the day everything is fine.
The doctor seems smart, he is praised.
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Adenoids, Nasonex and how tired I am of thinking about it
Daughter 4 years old. Not a garden one, but we have an active life and there is a children's group all the time. She rarely got sick, although she had snot quite often, but it was easily treated. About two weeks ago I started to have a nasal sound, then my nose started getting stuffy at night. I suspected adenoids and n.
Snotty everyday life
It's just snot, no big deal. Dan gurgled at night, oh no wonder he passed out in the car yesterday. God, how sick he is! He just cried half the night. I couldn’t give him breasts, he didn’t even ask. I didn’t drink anything I was given. He doesn't drink or eat at night. This is of course a plus.
Adenoids
This is the situation. We treated our daughter’s adenoids for a year and a half. Anything possible, courses, not courses, with different doctors, several ENT specialists, a pediatrician, etc. and so on. Irs-19, Sinupret, Tonsilgon, Lymphomyosot, Polydexa, Nasonex, Avamis, nasal rinsing - you name it.
She nasally, snored and all that. As a result, they were removed in October last year (the doctor said that they were huge, not even the third degree from which they are removed). The swelling after the operation subsided within a week, she was breathing normally for a week (maybe more, but I remembered the week).
Then it started.
adenoids and nasal rinsing
Good afternoon, girls! I would like to ask for advice. My son is 2.10, when we went to kindergarten, of course, he began to hurt and adenoids came out. They give rise to a runny nose, otitis media and persistent rhinitis. One doctor advises constantly rinsing, another categorically says not to rinse.
Last month we washed out Rhinostop with Aqua and as a result there was otitis and fluid in the ear, which all ended with Otipax and Nasonex. This month we got infected from a friend, now Polydex and thuja oil (edas) and the ENT says not to rinse, but only blow your nose (suck snot) and polydex, and then thuja oil.
Another, on the contrary, told me to rinse my nose more intensively.
ENT in the first nursery
Girls, who was treated? Reviews? In December, another one was there; her son was treated by her. Then I looked on the Internet, and she transferred from an adult clinic (what experience do I think she has of checking adenoids? They practically don’t happen in adults).
I decided not to go to her with my little one. And then otitis again ((We came to our clinic, and there was a new ENT specialist. And she was the first one who did not prescribe Otipax for us (before that we were treated either at the regional clinic or with Ponomarev).
They treated it like this: AB, Polydex in the nose, Polydex in.
Need reviews about the drug Polydexa
Please write down who was prescribed these nasal drops. I read the instructions and was shocked by the side effects and contraindications)) The little one has clear nozzles, not profuse, but for more than a week. The adenoids are slightly enlarged. The instructions for the drug say “for the treatment of rhinitis.” I'm not sure that my son has rhinitis. And for viral diseases, Polydex is contraindicated, as they say.
Doctors' opinion
Oleg, 54 years old, therapist, Izhevsk
Both medications are effective in combating inflammatory pathologies of the nasal sinuses. Polydexa is considered a safer medication because it is better tolerated. I also use Nasonex in my practice, but less often. I try not to prescribe this drug to children due to the increased risk of negative reactions. I do not recommend combining these drugs.
Victoria, 38 years old, therapist, Perm
These products do an excellent job with various types of rhinitis. Polydex is best used for inflammation of the maxillary sinuses and bacterial complications, since the medicine contains antibiotics. Nasonex is more effective in combating allergic reactions. Due to the fact that both drugs contain glucocorticosteroids, they should be used simultaneously only in cases of advanced pathological processes.
III. What are the indisputable advantages of Isofra over other nasal competitors?
As already mentioned, “Isofra” is one of the few antibiotics that exhibit minimal penicillin-induced pathogenic complications, disorders in the digestive organs (diarrhea, diarrhea, bloating). This medicine, unlike Nasonex, Polydex, silver-containing pharmacological drugs, hormonal drugs (Rinofluimucil), is prescribed under the supervision of a doctor, to the youngest patients (from 3 months).
Articles on the topic Treatment of adenoids with folk remedies: the most effective healing solutions, ointments, procedures
Isofra is widely used as an effective preventive medication. The medication “recognizes” just beginning adenoid pathogenesis in the nasopharyngeal locations of children. Slowly but methodically destroys the membrane cellular (gene) level of viral, pathogenic, and malicious bacterial strains.
Otolaryngologists, with primary suspicions of adenoid invasion, prefer to prescribe Isofra rather than another nasal medicine as a proactive technique. Especially when it comes to infants, weakened children (after prolonged somatic illnesses) - influenza, sore throat, chronic acute respiratory viral infections, acute respiratory infections.
"Isofra" must be administered in the post-surgical period, as a preventive measure to prevent postoperative bacterial infections. Moreover, children easily tolerate the use of Isofra without negative symptoms.
The drug is available only in the form of a spray, in vacuum packaging (can), with a built-in cap-nozzle (spray). The medicinal mixture is supplied under moderate pressure with a fine dispersion consistency. “Isofra” is used to treat the nasal passages (before the initial rinsing of the nasal canals with salt water). The medicine has the best effect if it is not stored for a long time (you should not buy it for future use). The course of treatment lasts 7-10 days, so the drug should be purchased at the pharmacy after a doctor’s prescription and used immediately. It is not recommended to leave the remaining mixture unused (for another time). Framycetin quickly decomposes and loses its clinical properties.
Composition and principle of action
The drug "Isofra" is produced by the manufacturer as a spray for spraying into the nasal passages - to achieve maximum local effect on tissue. The convenient shape of the bottle, with its correct vertical position, with a special nozzle, allows you to deliver the solution directly to the source of inflammation.
The main antibacterial substance of the spray is Framycetin, a representative of the aminoglycoside subgroup. It is characterized by a wide spectrum of activity not only against gram-positive, but also gram-negative pathogens. However, the drug does not have the required effect on anaerobic agents.
Isofra spray is also useless if the appearance of nasal discharge is allergic.
The mechanism of the bactericidal effect of Framycetin is based on its penetration through the cell membrane of pathogenic microorganisms, slowing down their protein synthesis, which is why they subsequently die.
Excipients of the medication are distilled water and preservatives. They help the main substance to show its best side. Isofra drops are not available. After all, the form of the spray for therapeutic measures in the oropharynx area is optimal and safer. Systemic absorption of the active substance does not occur, so adverse reactions occur extremely rarely.
