Mucolytic drug “Lazolvan” – tablets, syrup, solution

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Shutofedova Ksenia Yurievna

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Doctors often began to prescribe inhalations with lazolvan and saline solution for respiratory infections. Why? The fact is that the main drug, lazolvan, contains ambroxol, which in turn helps to quickly restore breathing. Doctors prescribe similar inhalations to both adults and children. The main mechanism of action is the removal of inflammation and swelling of the mucous membrane, thereby the active components of the drugs are concentrated in the lungs and create a therapeutic effect.

Brief information about the drug

Lazolvan for inhalation helps with coughs, as it belongs to the group of mucolic expectorants. The main component helps to quickly rid the patient of accumulated mucus, thereby significantly facilitating the functioning of the respiratory system. In addition, the drug stimulates and tones breathing.

Despite the fact that the drug is available without a prescription, you should consult a doctor before performing the inhalation procedure, because the medicine has contraindications.

Recommended reading: Inhalations with soda.

Description of the drug

Ambroxol hydrochloride, the active component of Lazolvan, is a universal substance.

When it enters the body, it acts simultaneously in several directions:

  • Helps thin out sticky mucus. Thick sputum is difficult to remove from the bronchi. Liquefied mucus leaves the lungs much faster and easier;
  • The production of pulmonary surfactant is stimulated. This substance facilitates the removal of sputum, along with which bacteria and microbes come out. Thanks to this property, the healing process is accelerated, the cough becomes less painful;
  • The work of the microscopic cilia that line the bronchial surface is activated. With the help of cilia, phlegm comes up and is removed from the lungs;
  • For dry cough, Lazolvan inhalation is not a remedy against the cough reflex. If sputum accumulates, the cough should not be suppressed. It is thanks to coughing that mucus is removed from the respiratory organs;
  • Lazolvan tablets contain lactose. This is important information for people who suffer from lactose intolerance. Lazolvan syrup contains benzoic acid, berry flavors, tartaric acid, glycerin. The inhalation solution contains water, citric acid, sodium salt;
  • The drug can accumulate in plasma and blood and enters the lung tissue. The excretion process is carried out through the kidneys along with urine.

Lazolvan is produced in several forms: tablets, nasal drops, inhalation and injection solutions, syrups. There is also Lazolvan syrup, intended exclusively for children. Children tolerate the drug well. The instructions indicate the minimum age at which it is allowed to give the medicine to a child. But pediatricians, if necessary, prescribe Lazolvan to children in the first months of life.

Composition of Lazolvan and saline solution for inhalation

One ml of the drug contains about 7.5 mg of ambroxol hydrochloride - this is the main component. In addition, the medicine also contains additional substances, namely citric acid, about 2 mg, sodium chloride, 6.22 mg, purified water, approximately 98.9 g.

Lazolvan also contains sodium hydrogen phosphate dihydrate and benzalkonium.

Fact : At the time of the study, the drug was noted to help increase secretions in the respiratory tract. In addition, Lazolvan is able to enhance the production of pulmonary surfactant in a short period of time, thereby stimulating ciliary activity.


During complex therapeutic treatment of patients with chronic obstructive pulmonary disease, it was noted that a positive result was observed after 1.5 months. After completing the course, the severity of exacerbation in patients decreased.

Saline solution – 0.9% aqueous solution of sodium chloride (NaCl). The solution is used not only for inhalation, but also as a solvent for intravenous and intramuscular manipulation. Saline solution does not contain potassium salts, so if you use pure saline solution in treatment, it does not bring a positive effect.

Inhalation with saline solution

Saline solution is a 0.9% solution of salt in water. Such inhalations have no contraindications and can be used by patients who are allergic to medications. They are indicated for any type of cough. Inhalations with saline solution soften cough, thin mucus, and moisturize mucous membranes. In addition, salt is a natural antiseptic; its effect on pathogenic bacteria is destructive. This is the most delicate remedy for treating cough in babies.

A saline solution is poured into the inhaler and its vapor is inhaled. A nebulizer delivers an aerosol of saline solution to the lower respiratory tract. Thus, the paroxysmal cough is relieved and the sputum is liquefied.

Indications and contraindications

Lazolvan with saline solution for inhalation is prescribed in complex therapy:

  1. For acute and chronic respiratory diseases.
  2. COPD (chronic obstructive pulmonary disease).
  3. Bronchial asthma.
  4. Acute bronchitis.
  5. Chronical bronchitis.

In addition to these diseases, doctors may prescribe inhalations for an adult with bronchiectasis.

Good to know - How to properly inhale Pulmicort with Berodual?


Due to the fact that the active component penetrates the placental barrier, it cannot be used in the first trimester of pregnancy. However, extensive clinical experiments have shown that if the drug is used after 23 weeks, it does not have a negative effect on the fetus.

In rare cases, doctors may prescribe inhalations with Lazolvan and saline solution in the second and third trimester of pregnancy, but only if the potential benefit to the mother outweighs the potential risk to the fetus.

You might be interested in: Saline solution for inhalation during pregnancy.

Among the contraindications according to the drug instructions, individual intolerance to the composition is also noted. In addition, you should not use this method of treatment during breastfeeding.

Indications

For what diseases is lazolvan prescribed? Pulmonologists write a prescription for the following ailments:

  • bronchitis;
  • bronchial asthma;
  • pneumonia;
  • bronchiectasis;
  • damage to lung tissue.

For example, bronchiectasis is characterized by the accumulation of exudate in the dilations of the bronchial tissues, and only lazolvan is able to remove the accumulation of secretions from there.

If a child has a severe runny nose, take Lazolvan drops. They quickly relieve nasal swelling and do not dry out the mucous membrane. The drops help cleanse the nasal sinuses when exudate accumulates and remove mucus from hard-to-reach places in the nasal cavity. The use of drops must be approved by a doctor.

Contraindications

Inhalations with Lazolvan should not be carried out during any cough if the body temperature has risen above 38 degrees. This is a general prohibition when conducting inhalation sessions. Contraindications also apply to:

  • nosebleeds;
  • respiratory disorders;
  • heart ailments and pathologies.

When treating obstructive diseases, a preliminary procedure is necessary using drugs that dilate the bronchial lumens - Berodual and others.

Inhalations

Side effects

It is necessary to dilute Lazolvan in a nebulizer in strict proportions as prescribed by the attending doctor. Otherwise, side effects may occur. For example:

  • Heartburn;
  • Nausea, even vomiting;
  • Allergic reaction on the skin;
  • Dermatitis.

Often after inhalation, patients experience dryness in the throat or mouth, as well as abdominal pain. In addition, approximately 10% of patients who used this treatment method experienced dysgeusia, which means a disturbance in the sense of taste. In rare cases, anaphylactic shock is observed.

If any side effects occur, you should immediately consult a doctor.

Inhalations with Miramistin - recommended reading.

Composition and release forms

Manufacturer of the drug - Boehringer Ingelheim LLC

The active ingredient of the drug is ambroxol hydrochloride . In the nasal spray, the active substance is tramazoline hydrochloride . The content of ambroxol hydrochloride in different release forms differs significantly, namely:

  • Adult syrup contains 30 milligrams of the active substance per 5 milliliters of the drug; children’s syrup contains 15 milligrams with a dosage of the drug of 5 milliliters.
  • The solution for inhalation and oral administration contains 7.5 milligrams per 1 milliliter of the drug.
  • One Lazolvan tablet contains 30 milligrams of the active substance, and one lozenge contains 15 milligrams.

Thanks to the wide range of forms of the drug, you can choose a remedy for any patient, be it an adult or a child, taking into account the factors of the disease and their degree of complexity.

A nasal spray is a drug with the ability to constrict blood vessels. The drug appears transparent, liquid, has a yellowish tint with a characteristic eucalyptus aroma. Prescribed as therapy for respiratory diseases.

The solution for inhalation and oral administration is a clear, slightly brown liquid. For inhalation of this solution with saline, the dosage is determined solely on an individual basis, depending on the complexity and nature of the disease. Inhalations with Lazolvan solution and saline solution are carried out in a course.

Lazolvan syrup is a clear, colorless liquid with a strawberry odor. This form of the drug is intended for internal use.

Lazolvan tablets are taken orally, and lozenges are dissolved.

How to do inhalations with saline solution and Lazolvan correctly


Nebulizer
In order to achieve the maximum therapeutic effect, it is necessary to use any modern equipment. Recently, a nebulizer has been actively used.

The nebulizer itself is a device that sprays the drug into small particles.

Before starting the procedure, you need to properly assemble the nebulizer, study the operating instructions, and also know how to care for the device and store it.

You might be interested in: Inhalation with a nebulizer with saline solution.

Rules for inhalation with lazolvan and saline:

  1. The patient must be in a sitting position at the time of inhalation. As for children, the procedure can be performed in a lying position, but you need to buy a mesh nebulizer.
  2. The procedure should be done 1.5 hours after the main meal and physical activity.
  3. Sprayed into tiny particles, the main components of the medicine are inhaled through the mouth using a special nozzle, and exhaled through the nose.
  4. After the procedure, the patient needs to take a deep breath in order to provoke a coughing attack.
  5. Dilute Lazolvan and nat. solution in the required dosage, and the temperature of the finished solution should not exceed 37°.

In addition to these recommendations, doctors strongly do not recommend performing the procedure before bedtime. After all, the drug stimulates secretion and removes mucus, and this can cause a severe cough.

We recommend reading: How to properly inhale with a nebulizer.

Bottom line

We found out for which cough inhalations with Lazolvan are prescribed. This drug is completely safe and can be used for inhalation and treatment of infants. Lazolvan can also be used by pregnant and lactating women, because it does not have a harmful effect on the fetus. However, you cannot prescribe yourself treatment with the drug - there are many contraindications for use. Only a doctor can prescribe treatment for bronchopulmonary diseases.

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Preparation of solution and dosage


Before you begin the procedure, you need to know how to dilute Lazolvan and saline solution.

Note that pure saline solution is unsuitable and does not give a positive result. The two drugs must be diluted in a 1:1 ratio.

For a child under 2.5 years of age, dilute in the ratio: 1 ml of the main medicine and 1 ml of NaCl (saline solution).

At the age of 6 years , it is necessary to prepare the following ratio: 2 ml of Lazolvan and 2 ml of saline solution. Inhalations in children should be done 2 times a day, the duration of each procedure should not exceed 3 minutes. The course of treatment depends on the severity of the disease. For mild cases of the disease, the course ranges from 3–4 days, for severe cases up to 6 days.


For inhalation with lazolvan and saline, the dosage for adults is 3 ml of each drug. How long does it take to inhale? In childhood, as indicated above, 3 minutes is enough, but for an adult, doctors can prescribe a duration of 5 minutes. If during this time the patient experiences discomfort, then it is necessary to stop the procedure and repeat after a while.

It is important to understand that the dose of medication should not be increased, otherwise side effects may occur that complicate the course of the underlying disease.

Patients often ask the question, how long does the therapeutic effect last? Only a doctor can answer this question, since everything depends not only on the severity of the disease, but also on the individual susceptibility of the patient.

We recommend reading the article “How effective are inhalations with Pulmicort?”

Medicines for the treatment of colds and flu Lazolvan Solution for oral administration and inhalation

Good afternoon Let me start with the fact that I consider Lazolvan itself to be a good cough remedy, but not for babies under one year old. I will share with you my sad experience.

It all started when we returned home from our grandparents, where my grandfather was sick. Despite all the measures taken, after a couple of days, the baby began to cough a little and sniffles appeared. At that time, we were 4 months old.

It was on Saturday, we immediately got ready in the morning and went to the pediatrician on duty. She listened to us and said that everything was fine, her lungs were clean. To treat sniffles, everything was standard - rinsing with Aqualor/Aquamarine, and, if necessary, vasoconstrictor drops at night. And for the cough she prescribed us to drink Lazolvan or Ambrobene. Since we had a lazolvan at home, we settled on it. By the way, when asked when we should come for an examination, the doctor said that once again it was better not to go to the clinic and not get sores.

We drank Lazolvan for 4 days, and the cough only worsened; on the 5th day I intended to go to the pediatrician again with the baby. But at night our temperature rose to 38, and I decided to call an ambulance. The doctor arrived, listened to us and diagnosed “obstructive bronchitis.” Immediately asked what and how they treated it. I told about Lazolvan, she said that such little ones should not be given Lazolvan to drink, but only do inhalations! The doctor was surprised that, having a nebulizer at home, they did not prescribe us inhalations. Together with her, we immediately inhaled with Berodual. Since we were in the Moscow region, we refused hospitalization. The doctor herself said, if possible, it’s better to go to the Morozov hospital in the morning. That's what we did. I won’t describe how my night went, and how I reproached myself and still reproach myself.

We were lucky, they didn’t leave us in the hospital, they prescribed treatment and sent us home. We then completed our treatment in a private clinic.

Of course, after all this, I began to study information on Lazolvan on the Internet. Everything turns out to be very simple, lazolvan liquefies mucus, and at this age the baby cannot cough it up on his own, all this accumulates inside and leads to such serious consequences.

Now, after a doctor’s appointment, I double-check all the information by reading reviews on the Internet! I hope mine is useful too.

By the way, the well-known doctor Komarovsky is very categorical on this issue. He just says that such drugs should absolutely not be given to children under 2 years of age!

Now, whenever there is any cough or sniffles, every other day I take my child for an examination to the pediatrician. It's better to be safe than sorry!

Take care of your kids!

Why is Lazolvan used in the treatment of sinusitis?

For successful treatment, it is necessary to free the sinuses from frozen mucus and relieve swelling. The use of Lazolvan for sinusitis helps achieve this.

The active substance enhances the separation of mucous contents of the nasopharynx. At the same time, the drug causes the membrane to secrete an additional amount of secretion. It becomes liquid, easily separates, and breathing through the nose is restored.

The peculiarity of Lazolvan is its fast action. The effect occurs 15 minutes after application. The mucous membrane is moisturized. Breathing becomes comfortable.

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