Erespal
Active ingredient : Fenspiridum Hydrochloride . This substance has the following effects:
- Anti-inflammatory.
- Blocking the production of mucus in the bronchi.
- Antispasmodic – relieves bronchospasm.
- Antihistamine (anti-allergic).
Erespal acts in such a way that it not only eliminates the cough, but acts precisely on the cause that caused it. Release forms: 80 mg tablets and 2 mg/ml syrup, 150 ml in a bottle. The drug can be used by both adults and children. Children are prescribed mainly syrup. Manufacturer Erespal - French. This is an imported and very high-quality manufacturer, but, unfortunately, not very cheap.
The drug is quickly absorbed in the body and begins to act after 1.5 – 2 hours, the syrup – after an hour. The dosage is calculated based on the age and weight of the patient. Erespal can be taken from 2 years of age. If the patient has diabetes mellitus, then syrup should not be given as it contains sucrose.
The medicine has a sedative effect, so it is not advisable to drink it together with sedatives and alcohol, as the sedative effect will be increased. You need to drive very carefully, as drowsiness may occur. During pregnancy and lactation you should refrain from taking it.
Individual reactions may develop, such as allergic reactions, various rashes, and swelling.
Composition and action
The syrup is produced by a French pharmaceutical company; in Russia, its production is carried out by the Pharmstandard-Leksredstva corporation. In pharmacies it is presented in plastic bottles with a volume of 150 or 250 ml. The required doses are measured using a measuring cup.
The medicine is a clear liquid with a yellow or brown tint. During storage, a sediment may appear in it, which disappears when shaken. A plus is the fact that the drug is sweet, it has a honey-vanilla aroma and children like it.
The main component of Erespla is fenspiride; in syrups it has the form of hydrochloride. There are 200 mg of active substance per 100 ml of medicine. This means that from one milliliter of the drug the patient receives fenspiride in the amount of 2 mg. The list of auxiliary components of Erespal syrup includes licorice root (extract).
To prevent the drug from deteriorating and losing its liquid consistency, potassium sorbate, artesian water and several other ingredients are added to it. The syrup is sweetened by sucrose, and flavors of natural origin give it a pleasant aroma. But their quantity is insignificant (approximately 0.29 mg per 100 ml).
The drug Erespal relieves the inflammatory process, it acts directly on the cause of inflammation, and this is its main advantage in comparison with analogues. Similar drugs exclusively eliminate cough and promote sputum discharge.
Erespal syrup blocks H-1 histamine receptors. By binding to inflammatory activators, these receptors lead to the appearance of edema, which is how the body defends itself. When H-1 histamine receptors are blocked, no matter how much histamine is synthesized, the body stops responding to provocations with edema. Due to the action of Erespal, the release of biologically active components (arachidonic acid products, free radicals) that support inflammation is reduced. These substances, in addition to maintaining the inflammatory reaction, also cause a narrowing of the bronchi.
As a result of bronchial stenosis, little air enters the body, it begins to suffer from a lack of oxygen, and shortness of breath occurs. Thanks to Erespal, which blocks the release of substances that support inflammation, narrowing of the bronchi is prevented. Alpha adrenergic receptors take part in the synthesis of difficult to separate sputum. If Erespal acts on these substances, young patients do not have to suffer from phlegm.
The effect of the syrup is comparable to non-steroidal anti-inflammatory drugs and glucocorticosteroids. But Erespal advantageously differs from them in the absence of side effects.
Attention! Erespal is not an antibacterial drug. They are not allowed to treat diseases that have developed due to pathogenic bacteria entering the body. But this does not mean that it cannot be used in complex therapy as an anti-inflammatory drug that relieves swelling and allergic reactions.
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Erispirus
The active ingredient is the same as in Erespal. It is used for the same respiratory diseases. There is a form of tablets of 80 mg and syrup of 2 mg/ml (150 ml bottle). Children under 18 years of age are recommended to take it in syrup. . Use with caution with sedatives, during pregnancy, diabetes, gastrointestinal diseases, sensitivity to fenspiride and additional components.
Take 1 tablet orally before meals 2-3 times a day, for children – 4 mg/kg per day . Absorbed quickly and excreted through the kidneys. The drug is prescribed only by a doctor, there is no need to self-medicate, and does not replace antibacterial therapy, therefore, if necessary, it is taken in combination.
Side effects:
- Gastrointestinal tract: abdominal pain, nausea, vomiting, loose stools.
- Cardiovascular system: tachycardia, sharp decrease in pressure (hypotension).
- General condition: severe fatigue, weakness, lethargy.
- Skin: various rashes, erythema.
Erespal drug. Analogs
The drug "Erespal" has been sold in Russia for more than 10 years. It is very effective in the treatment of bronchopulmonary diseases. Swelling of the bronchi, resulting from exudative phenomena, makes it difficult for sputum to pass away, and it becomes viscous. This causes difficulties in the evacuation of bronchial secretions. The drug "Erespal" effectively copes with bronchial obstruction. It normalizes sputum discharge, restores gas exchange in the lungs, and increases their vital capacity.
The drug "Erespal" has antibronchoconstrictor and anti-inflammatory activity. Fenspiride, the active substance of the drug, increases the secretion of pro-inflammatory factors and bronchial obstruction. It has an antispasmodic effect.
The auxiliary substances contained in the drug "Erespal" are:
- licorice root extract;
- honey aroma;
- vanilla extract.
The medicine is available in tablet form and syrup form.
The drug "Erespal" is well absorbed from the gastrointestinal tract. This pharmaceutical drug is excreted 90% in the urine and 10% through the intestines.
Side effect
The use of the drug may cause nausea, moderate tachycardia, epigastric pain, urticaria, erythema, gastrointestinal disorders, angioedema, drowsiness, rash.
special instructions
Erespal syrup contains a yellow dye that can cause allergic reactions. People who are hypersensitive to aspirin may also be allergic to fenspiride.
The drug "Erespal". Analogs
When treating bronchitis, many people wonder what can replace Erespal? Does it have analogues?
An excellent remedy that can replace this medicine is Bronchicum syrup. This drug has an antimicrobial, anti-inflammatory, expectorant effect. The pharmaceutical product "Bronchicum" helps to dilute sputum and speed up its evacuation. However, caution should be exercised when using it, as the patient may experience allergic reactions, such as urticaria, skin rash, and Quincke's edema.
Does the medicine “Erespal” have any analogues? This question worries many people suffering from constant bronchitis. The described drug has structural analogues of the active substance - fenspiride hydrochloride. That is, any medicine containing this component is an analogue of Erespal.
How to replace Erespal? Other bronchitis medications can be used instead. For example, pharmaceuticals such as “Fluditek”, “Pulmex-baby”, “Sinekod” drops, “Bronchipret”, “Bronchicum”, “Lazolvan” syrups and some other drugs. The named medications are all analogues of the drug “Erespal”.
A wonderful remedy used for bronchitis is the drug Fluditec. It has an expectorant and mucolytic effect and increases the viscosity of sputum. However, you should pay attention to the side effects of this medication: diarrhea, nausea, flatulence, vomiting, gastrointestinal bleeding, epigastric pain.
Lazolvan syrup is another remedy that can replace Erespal. Analogues like this medicine help to liquefy sputum, establish a balance between its mucous and serous components, and release lysosomes from Clara cells. When using the medication, heartburn, nausea, gastralgia and vomiting may occur.
Any potent drugs that are effective in treating bronchitis are suitable as analogues of the drug Erespal.
So, the drug “Erespal” has analogues. You should look for them in pharmacies, learn about them in the press and on the Internet on specialized websites and forums.
What common?
Erespal and Erispirus are considered analogues. They have the same active ingredient and mechanism of action. Available in the same dosage forms and dosages - 80 mg tablets. syrup 2 mg/ml (bottle 150 ml).
They are used to treat the cause of cough in combination with antibacterial or anti-inflammatory therapy. Contraindications and side effects are no different from each other. Fenspiride can provoke adverse reactions from the nervous system: fatigue, mental confusion, depression, confusion, panic attacks.
Erespal contraindications and side effects
In general, there are several general contraindications for the use of tablets or the syrup dosage form of the drug.
- detected high sensitivity to the components of the drug;
- fructose intolerance due to the content of sucrose;
- in the presence of diabetes mellitus – diseases of any type;
- children up to two years of age.
If you have any doubts about the use of the drug for children or adults, it is recommended to consult with your treating specialist. Children are contraindicated to use drugs in tablet form.
Use during pregnancy
Pregnant women are not strictly prohibited from taking the drug, but it is recommended to consult a pharmacist who will advise on the best way to start using the drug. If during a treatment course a woman discovers that she is pregnant, she must immediately interrupt treatment and consult her doctor. During lactation, the use of this drug is also not recommended.
Alcohol compatibility
for use if alcohol . It is better to consult a doctor and ask everything about the features of using this drug.
Side effects
They are present and are classified according to their prevalence: some are more common than others, and some occur extremely rarely. Among the first are:
- gastrointestinal disorders;
- nausea and vomiting.
More rare:
- moderate tachycardia;
- drowsiness and apathy;
- rash on the skin;
- asthenia.
If side effects are serious or unwanted problems occur, you should notify your healthcare professional.
Main differences
Despite the fact that the drugs have the same components, there are several significant differences. The main difference is different - a French pharmaceutical company created in 1954. This is a proven company that makes quality products. Sandoz is an international company created in the 19th century. This company produces a wide variety of medicines.
Due to the fact that different companies produce medicines, their prices also differ. Servier is an imported company, its drugs are more expensive than their analogues from other manufacturers. Erespal in tablets costs 350-400 rubles , syrup costs from 270 to 310 rubles . Erispirus is 2 times cheaper in price. That is, to undergo a course of treatment with Erespal, you will need to spend approximately 800-1000 rubles , a course of Erispirus will be 2 times cheaper.
In terms of effectiveness, an imported drug may be better than a non-imported one.
Another difference is that Erespal contains Glycyrrhiza glabra (licorice) as an auxiliary component. It is mucolytic, meaning it makes sputum less sticky and easier to cough up. Erispirus does not have such a component.
Erispirus and Erespal - what is the difference?
Updated As of February 14, 2019, Roszdravnadzor decided to withdraw Erespal and analogues (including Erespirus) from sale due to the risk of heart rhythm disturbances.
The slight difference between the drugs is who makes them. Erespal is a product of the French company Les Laboratoires Servier, which, among other things, is produced at the Russian enterprise Pharmstandard-Leksredstva. Erispirus is produced by Sandoz (Slovenia). Depending on this, the composition of the formative substances differs slightly (see the packaging for more details).
By the way, this is how Erespal differs from Erispirus: among its auxiliary components, it contains licorice extract, which is used in folk medicine as a mucolytic.
From consumer reviews it follows that the therapeutic effects of the drugs are very similar. Many patients note improvement (decreased episodes of coughing and shortness of breath) within a short period of time. However, side effects such as tachycardia, nausea or allergic reactions are sometimes reported.
It should be borne in mind that the drugs in question contain a histamine receptor blocker, so they cannot be used based solely on approval on Internet sites. Remember to get medical advice about the proper treatment for your condition. An overdose can be dangerous, so the duration of use and the daily amount of medication should be prescribed by a doctor.
