Antibiotics for green snot in children

Release form and composition

"Tsiprolet" is produced in India in three forms, which are eye drops, a solution for intravenous injections and coated tablets with a dosage of 250 mg and 500 mg.
The main ingredient in each of these drug options is called ciprofloxacin. Since the solid and injectable forms can negatively affect the formation of the skeleton, such “Tsiprolet” is not prescribed in childhood, and only because of its predominantly local effect is the medicine in the form of drops permissible for use in children. This form of the drug is prescribed to small patients over 1 year of age.

There is also a medicine called “Tsiprolet A”. This is a tablet medicine, which, in addition to ciprofloxacin, also contains another active compound - tinidazole. This drug is also contraindicated in people under 18 years of age.

One milliliter of Ciprolet eye drops contains 3 mg of ciprofloxacin, which is in the form of hydrochloride in this medicine. The solution itself is clear and usually colorless or slightly yellowish. It is placed in plastic bottles in a volume of 5 ml. The excipients in this medication are the standard ingredients for eye drops - benzalkonium chloride, water, hydrochloric acid, sodium chloride and disodium edetate.

Tsiprolet eye drops in the nose for children

Tsiprolet has a wide spectrum of action, due to which it is often prescribed to adult patients for the treatment of pneumonia, sore throat, pyelonephritis, sinusitis, adnexitis and other infectious diseases. Tsiprolet is prescribed to children only in the form of eye drops; other forms of release are contraindicated for patients under 18 years of age.

Description and composition of the drug

Tsiprolet is a drug with antibacterial properties. The active component of the drug is ciprofloxacin. This substance belongs to the fluoroquinolone family and helps to actively suppress the activity of pathogens such as Klebsiella, staphylococcus, streptococcus, enterobacteria, chlamydia, E. coli, citrobacter, diphtheria corynebacterium, etc.

The auxiliary components of the medicine include:

• Mannitol.
• Acetic acid.
• Sodium acetate.
• Water.
• Benzalkonium chloride.

The medication is available in the form of tablets, injection solution or eye drops.

On the shelves of pharmacies you can also find another form of the drug in question - Tsiprolet A. This drug is available in tablet form. Its difference from the usual Ciprolet lies in the presence of two active components in the tablets: ciprofloxacin and tinidazole.

Directions for use and dosage in children

The dose for children depends on how severe the disease is. For mild damage, administer 1 drop into the eye every 4 hours.

For moderate and severe cases, 2 drops per eye will be required, while the doctor can increase the frequency of instillations to 6–8 times a day. If necessary, your doctor may recommend eye drops every 15, 30, or 60 minutes.

As the inflammatory process subsides, the dosage and frequency of instillations decreases.

The duration of therapy usually does not exceed 5 days, although if necessary, treatment can last up to 10–14 days. During treatment, it is necessary to carefully monitor the condition of the child's eyes. If after 2-3 days of using the drops there is no improvement, then the doctor can choose another, more effective medicine.

Side effects

Tsiprolet is a potent drug and during treatment can provoke the development of undesirable reactions. So, after using the drops, a child may experience:

• Swelling of the conjunctiva.
• Photophobia.
• Feeling of sand in the eyes.
• Burning, itching.
• Blurred vision.
• Increased lacrimation.

In addition, patients with corneal ulcers may develop a white crystalline precipitate. It is also possible to develop keratitis, superinfection, and corneal infiltration.

Interaction with other drugs

• When using Tsiprolet drops with antimicrobial agents (antibiotics, aminoglycosides, metronidazole, clindamycin), as a rule, an increase in the therapeutic effect of each drug is observed.
• If the organs of vision are damaged by streptococcal infection, Tsiprolet can be combined with Ceftazidime, Azlocillin and other beta-lactam antibiotics.
• If affected by staphylococcus, drops can be combined with Vancomycin and isoxazolepenicillins. This combination helps to increase the therapeutic effect.
• To combat anaerobic infections, it is possible to combine the drug with Clindamycin or Metronidazole.

Tsiprolet cannot be used simultaneously with physically or chemically unstable drugs with a pH value of 3–4.

special instructions

If the doctor has prescribed two or more types of eye drops for the child, then an interval of 10–15 minutes must be observed between instillations.

Source: //sustavo.ru/info/glaznye-kapli-ciprolet-v-nos-dlja-detej/

Description of the drug

Tsiprolet eye drops are produced in India. The drug is produced in plastic bottles with a 5 ml pipette. The cost of one package varies about 50 rubles.

The drops contain an aqueous solution of ciprofloxacin hydrochloride (group of first generation fluoroquinolones). 1 ml of the drug contains at least 3 mg of the active ingredient and additional substances:

• benzalkonium chloride (solution) - 0.0002 ml;
• hydrochloric acid - 0.000034 ml;
• sodium chloride - 9 mg;
• ethylenediaminetetraacetate - 0.5 mg;
• distilled water - 1 ml.

It is important to take into account which group of antibiotics the main active component of Tsiprolet belongs to.

Substances in this group are similar to antibiotics in their action, but differ in chemical formula and have no analogues in nature.

Tsiprolet is effective against gram-negative bacteria (gonococci, Escherichia coli, Pseudomonas aeruginosa, chlamydia) and gram-positive (staphylococci, pneumococci). The drug is also used in the treatment of tuberculosis infection, due to its activity against mycobacteria. It is not recommended to use Tsiprolet against anaerobic infections.

Action of eye drops

The drug is not available in the form of ear drops. Release form: film-coated tablets, eye drops and solution for infusion. Analogs of Ciprolet are produced in the form of ear drops, for example, Ciprofloxacin eye and ear drops, Tsipromed ear drops. The course of treatment and dosage is determined by the doctor!

The following regimen for use in otitis media is most often prescribed: the solution should be at room temperature (or body temperature) when used to avoid vestibular stimulation. Ciprofloxacin eye and ear drops are instilled into the external auditory canal, 3-4 drops 2-4 times a day or more often, depending on need.

Tsiprolet solution is intended for the treatment of infectious eye diseases. It copes well with conjunctivitis in acute and chronic forms.

The local action of the drops has a weak antibacterial effect and does not bring any discomfort or side effects that accompany conventional medications for the common cold. Therefore, when asked whether it is possible to drip Tsiprolet into the nose, doctors answer in the affirmative.

The drug, prescribed by a doctor taking into account the diagnosis and physical characteristics of the patient, has virtually no side effects inherent in antibiotics in other forms. The drug does not enter the gastrointestinal tract and organs of the genitourinary system.

Tsiprolet eye drops in the nose of a child

“Tsiprolet” is a drug with a wide spectrum of action aimed at combating microbes. Treats infections of varying complexity that were caused by drug-sensitive microorganisms.

Indications for use

“Tsiprolet” tablets and solution are used to treat diseases caused by various microorganisms (Haemophilus influenzae, Enterobacter, Staphylococcus and Streptococcus, Salmonella, Eschicheria and Mycoplasma)

These are diseases:

1. Respiratory tract (obstructive bronchitis, pneumonia, bronchiolitis, pleurisy, lung tissue abscess)
2. Genitourinary system (for pyelonephritis, cystitis in women, prostatitis, STDs (acute gonorrhea, urethritis))
3. Affecting the nose, ear and pharynx (sinusitis, ethmoiditis, otitis media, tonsillitis).
4. Gynecological area (oophoritis, inflammation of the appendages, endometritis)
5. Peritoneal organs (peritonitis, peritoneal abscess, cholecystitis)
6. Skeletal system (osteomyelitis, purulent arthritis)
7. Gastrointestinal tract (diarrhea of ​​bacterial origin, dysentery, salmonellosis, typhoid fever)
8. Skin (infected burns, soft tissue injuries, suppuration).

Please note that if sinusitis can be without a runny nose. Surprised? Then read the article on his website: sinusitis without a runny nose - causes, treatment.

The antibiotic is used in therapy after surgery, incl. and preventive, in dentistry, during flux therapy and for the prevention of bacterial complications of tooth extraction operations.

“Tsiprolet” eye drops treats infections of the eyes and appendages:

• Keratoconjunctivitis
• Corneal ulcer
• Blepharium
• Meibomyitis.

The drug is effective against infection of the eyes and appendages after interventions in the field of ophthalmology.

Compound

“Tsiprolet-250” and “-500” include ciprofloxacin hydrochloride monohydrate (250 or 500 mg of ciprofloxacin).

Eye drops contain ciprofloxacin hydrochloride (3 mg of the substance in 1 ml of solution). Additionally - sodium chloride, benzalkonium, hydrochloric acid, distilled water.

In solution for infusion, 200 mg of ciprofloxacin hydrochloride per 100 ml of solution.

Medicinal properties

The antibacterial substance ciprofloxacin, having a fatal effect on the reproductive system of bacteria, because of which they do not have the ability to divide, exhibits bactericidal properties, destroying microbial membranes.

The drug reaches its greatest amount in the blood 1-1.5 hours after administration, penetrates into organs and tissues, and after 2 hours is concentrated in greater quantities than in the blood.

The medicine is eliminated from the body through the functioning of the excretory system with urine, feces and bile.

Average price from 50 to 190 rubles.

Tablets “Tsiprolet”

Round white (cream) convex coated tablets. In cross section - a solid mass of white (yellowish-cream) color, bitter in taste.

The antibiotic is available in blisters of 10 tablets (250 and Tsiprolet 500 mg). Additionally packed in a cardboard box with 1-2 blisters.

Mode of application

“Tsiprolet” tablets are used under the supervision of the attending physician at the same time of day. Unless otherwise specifically prescribed, the recommended dosage is:

1. Uncomplicated or moderate urinary tract infections - 2*125 mg
2. Respiratory tract infections, depending on severity and for complicated or severe urinary tract infections - 2 * 250-500 mg
3. Other infections, post-operative conditions (in dentistry in the treatment of flux, infections affecting the nose and ear) - 2 * 500 mg.

Severe infection of the body if the patient has concomitant diseases, the dosage can be increased to 1.5 g (2 * 750 mg) orally.

Against STDs and moderate cystitis in women, a daily dose of 250-500 mg is used.

For peritonitis, an antibiotic is prescribed in an amount of 0.5 g 4 times a day.

The duration of use depends on the severity of infection, the course of the disease, the presence of concomitant pathological conditions, and the patient’s test results.

The average price is from 50 to 70 rubles.

Solution for injections “Tsiprolet”

Liquid for injection is a clear liquid without any foreign particles. Available in glass bottles with a rubber stopper, 100 ml per bottle. Packed in a cardboard box. 1 box – 1 bottle.

Eye drops “Tsiprolet”

Eye drops are a clear or yellowish liquid. Available in polyethylene bottles with a pipette dispenser of 5 ml/bottle, additionally packaged in a cardboard box. 1 box – 1 bottle.

Contraindications

Before prescribing and taking the drug, you should find out whether the patient is at risk for taking the antibiotic. “Tsiprolet” cannot be used for:

1. Individual intolerance to the active substance (this also includes analogue drugs).
2. Pregnancy
3. Natural feeding
4. The patient is under 15 years of age.

During pregnancy and lactation

“Ciprolet” (tablets, injection solution and eye drops) is contraindicated for therapy in women with possible pregnancy. Ciprofloxacin overcomes the placental barrier, affecting the fetus. It passes into breast milk, so a mother’s child receiving antibiotic therapy should be switched to artificial feeding during treatment and for another 2-3 weeks after its completion.

Precautionary measures

“Tsiprolet” should be used with caution for therapy:

• Elderly people (after 65 years)
• Patients with epilepsy, organic brain damage, seizures, and other neurological pathologies
• Children from 15 to 18 years old
• Patients suffering from alcoholism
• Patients with multiple organ damage to the excretory system.

For this group of infected people, ciprofloxacin is prescribed in case of vital need.

Taking the medicine in combination with ethyl alcohol can cause severe damage to the central nervous system, therefore Ciprolet and alcohol are incompatible.

The antibiotic must be combined with drugs to rehydrate the body.

Cross-drug interactions

When administered together with NPS, the risk of seizures in patients with neuropathology may increase.

Preparations containing zinc and iron ions reduce the absorption of the drug in the stomach, so they should be taken 4 hours after taking the antibiotic.

The medicine showed good compatibility with antimicrobial drugs of different groups.

The infusion form is incompatible with solutions with a pH greater than 7.

Side effects

The antibiotic is usually well tolerated. In rare cases, nausea, vomiting, convulsions, even loss of consciousness, tachycardia, and arterial hypotension may occur.

Overdose

When using eye drops, overdose is extremely rare. In case of an overdose of tablets, symptomatic treatment is prescribed. There is no special antidote.

Storage conditions and periods

Tablets are stored at temperatures up to 25 degrees. In a place protected from light.

Eye drops are kept at room temperature in a dark place. Freezing eye drops is prohibited. The solution for infusion is stored in the same way as drops; it cannot be frozen either.

Analogs

Tablets and infusion solution can be replaced with antibiotics:

“Amoxiclav”

Sandoz, Switzerland Price from 223 to 946 rubles.

Antibiotic of the penicillin group. The active ingredient is amoxycycline, has a bactericidal effect on Staphylococcus aureus, Listeria, Enterococci, Haemophilus influenzae and Escherichia coli, Klebsiella, Proteus, Clostridia.

pros

• “Amoxiclav” can be used to treat children over 6 years old; a liquid dosage form (suspension) has been developed for them.
• The antibiotic Amoxiclav has little ability to cause side effects
• If necessary, Amoxiclav can be prescribed to pregnant and nursing mothers, if the use of antibiotics cannot be avoided

Minuses

• Penicillin intolerance is quite high, so Amoxiclav is prescribed with caution to patients for the first time
• The drug is excreted from the body mainly through urine, therefore it is contraindicated in patients with kidney pathology.

“Cifran”

Ranbaxy Laboratories Limited, India Price from 20 to 360 rubles.

A broad-spectrum antibiotic that contains the same active ingredient as Tsiprolet. Active against most gram+ and gram- bacteria (including staphylococcus, streptococcus). Available in the form of white (yellowish) oval tablets of 500 or 1000 mg of the substance.

pros

• The possibility of effectively starting treatment for patients with a bacteriologically unknown diagnosis, due to the wide spectrum of action of the drug

Minuses

• Affects the intestinal and vaginal microflora in women, and therefore must be combined with prebiotics and antifungal agents
• May cause toxic kidney damage, especially in patients with renal failure.

Eye drops can be replaced with the following drugs:

“Oftaquix”

Santen Oy, Finland Price from 200 to 230 rub.

An antibiotic used to treat purulent conjunctivitis. The active ingredient is levofloxacin. Can be used after ophthalmological operations and removal of foreign bodies from the appendages of the eyes. Available in the form of greenish-yellow eye drops in polyethylene bottles with a dropper nozzle.

pros

• Allowed for use in the treatment of conjunctivitis in children over 1 year of age
• Good compatibility with other eye drops and antibiotics

Minuses

• Inability to use in infants, women during pregnancy and breastfeeding
• High probability of side effects - burning, pain and itching in the eyes, irritation of the mucous membranes
• Oftaquix can only be dripped into the conjunctival sac, avoiding contact of the drug with the cornea of ​​the eye.

“Ciloxane”

Alcon-Couvreur, Belgium Price from 487 to RUB.

A broad-spectrum antibiotic, produced in the form of drops, which effectively treats infections of the eyes and appendages. Available in the form of eye and ear drops, eye ointments. Dispensed with a doctor's prescription.

pros

• The release of the drug in various forms makes it possible to effectively use the same medicine for inflammation of the eyes, appendages and ears.
• In special cases, drops may be prescribed to pregnant and nursing mothers

Minuses

• When used, discomfort in the eyes and blurred vision may occur.
• When using Ciloxan, you should not wear soft contact lenses, since the drug destroys their shell.

Download instructions for use

Source: //detki.shukshin-net.ru/ciprolet-kapli-glaznye-v-nos-rebenku/

Contraindications

Treatment with Ciprolet is in demand for various infections of the eyes and lacrimal apparatus, which are caused by microorganisms sensitive to ciprofloxacin. Drops are prescribed for children suffering from:

• conjunctivitis;
• blepharoconjunctivitis;
• blepharitis;
• keratoconjunctivitis;
• keratitis;
• corneal ulcers;
• dacryocystitis;
• meibomite.

The drug is also used as a means of prevention if a child has undergone surgery on the organs of vision, as well as after removing a foreign body from the eye or eye injury.

"Tsiprolet" is not prescribed to patients who have previously been found to have hypersensitivity to ciprofloxacin, another drug from the fluoroquinolone group, or any of the auxiliary ingredients of the solution. Drops are also not used for viral eye infections. In case of convulsive syndrome or impaired blood circulation in the brain tissue, treatment with this remedy should be supervised by a doctor.

Among the contraindications to the use of the product are:

1. Tsiprolet in tablets and solution for injection is contraindicated for pregnant and lactating women. But in the form of eye drops, it can be used to a limited extent under the supervision of a physician.
2. It is not recommended to use the drug if there are disorders of the cerebral vessels.
3. If you are particularly sensitive to fluoroquinolone antibiotics, you should avoid using Tsiprolet.
4. It is prohibited to combine the use of the drug with alcohol consumption.

Instructions for use

Most often, Tsiprolet drops are prescribed as a local antibacterial agent, 1 drop in each nasal passage. The treatment regimen is selected individually. In the case of an acute course of the disease, on the first day, four times the drug can be used with an interval of 6 hours.

The course of treatment should not exceed 5 days, as when using other forms of the drug with an identical composition.

Tsiprolet drops can be instilled into the nose of children starting from the age of three. But you cannot make a decision about using drops to treat children without consulting a pediatrician.

Application in otorhinolaryngology

Ciprofloxacin is used as ear drops. The ear canal is first carefully cleaned. The product, always at room temperature, is instilled into the ears, 4 drops, but not more than 4 times a day.

After using the drug, the patient takes a lying position for 15 minutes on the side opposite the affected ear.

In individual cases, a cotton swab with a medicinal composition is placed in the ear canal and left there until the next procedure. The course of treatment lasts up to 10 days, but can be extended as prescribed by a doctor.

The doctor may prescribe Ciprofloxacin-Acos for otitis media.

Ciprofloxacin-Akos is also effective for sinusitis, as confirmed by consumer reviews. The action of the drug is aimed at destroying bacterial microflora and relieves the disease in 5 - 10 days.

Side effects

Tsiprolet drops are not characterized by the usual side effects associated with the use of dosage forms based on ciprofloxacin. In rare cases, headaches may occur.

Some children may experience negative symptoms such as redness, slight soreness, itching or burning sensation after contact with Tsiprolet on the conjunctiva. In rare cases, the medication provokes discomfort in the eye, photophobia, decreased visual acuity, inflammation of the cornea, swelling of the eyelids and other symptoms.

Features of purchase and storage

Tsiprolet drops can be used no later than the expiration date indicated on the package. Residues in an opened bottle are not recommended for use after 30 days of storage.

The drug should be stored at room temperature (up to 22°C) and the medicinal liquid should not be allowed to freeze, so the bottle should not be placed in the refrigerator.

Tsiprolet eye drops are sold by prescription, so before purchasing such a medicine, an examination by an ophthalmologist is required. The average price of one bottle is 50-70 rubles.

The solution should not be heated above 25 degrees or frozen. The shelf life of the drops is 2 years, but after opening the bottle it is reduced to one month.

Reviews

The use of Tsiprolet eye drops in children receives mostly positive feedback. The medicine is said to be effective for various bacterial eye diseases, as well as inexpensive and easy to use. Its disadvantages include only a short shelf life of an opened bottle, and adverse reactions are detected very rarely.

According to reviews from specialists and patients who have used eye drops to treat ENT diseases, the effectiveness of Tsiprolet is many times higher than conventional remedies for the common cold.

Marina, 29 years old, Syzran: “When my baby (5 years old) and I once again went to the doctor instead of kindergarten, we were prescribed Tsiprolet drops. I was surprised that eye drops were prescribed as a treatment for the nose. But we decided to try anyway. It turned out to be quite an effective remedy. True, it does not work immediately. But somehow it passed unnoticed. But the doctor warned that it should not be used as regular drops for any runny nose. Still an antibiotic."

Valentina, 33 years old, Achinsk: “The drops are good. The doctor prescribed them for us for green snot. My daughter (7 years old) was diagnosed with otitis media. But the bottle is terrible. It also needs to be cut to be used. I made a slight mistake and it’s difficult to dose.”

Unlike vasoconstrictor drugs, Tsiprolet drops do not cause dryness in the nose. The reason for this effect is that the active antibacterial drug acts on the causative agent of the disease.

By destroying bacterial cells, ciprofloxacin does not reduce mucus secretion in the nose. Treatment occurs, and not the removal of symptoms of the disease, as happens when using ordinary drops for the common cold.

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Nasal diseases are often accompanied by green snot, especially in childhood. This symptom is a signal of a bacterial infection. The discharge turns green when neutrophils destroy bacterial cells. To determine the causative agent of the disease, it is necessary to do a bacterial culture. Based on the data obtained, and also depending on the severity of the disease, the otolaryngologist may prescribe antibiotics for green snot. But in some cases, treatment with other drugs is possible.