Taking antibiotics is an integral part of the treatment of bacterial forms of sinusitis of the maxillary sinus. Many drugs with antimicrobial action have been developed, differing in composition and duration of effect. Vilprafen Solutab is suitable for the treatment of sinusitis in adults and children; it also affects chlamydia, which can be a causative agent. The advantage of the medicine is its variability of use, low risk of adverse reactions from the body. Recommended for acute and chronic forms of the disease, as well as for the prevention of complications.
How does Vilprafen Solutab work and does it help with sinusitis?
Vilprafen is a modern macrolide antibiotic based on josamycin. It is active against gram-positive and gram-negative pathogenic bacteria and intracellular microorganisms. Inhibits DNA protein synthesis of pathogens, which leads to a decrease in their ability to reproduce and divide cells. It is recommended for the treatment of sinusitis of any severity; the active substance of the composition has virtually no effect on the gastrointestinal tract, unlike other antibacterial drugs.
The advantage of josamycin is its ability to affect pathogens resistant to the antibiotic erythromycin.
You can find out about the use of Oxolinic ointment for a runny nose here.
Composition and active substance
Wab is produced by a Dutch company in the form of tablets with a dosage of 500 mg and 1 g. The main substance is josamycin. It has a wide spectrum of action and is included in the WHO list of essential medicines.
- cellulose;
- silica;
- polysorbate 80;
- talc;
- magnesium stearate;
- aluminum hydroxide.
It is well absorbed by the body and does not accumulate in the kidneys and liver. It has low toxicity, making it suitable for the treatment of sinusitis in children.
For what forms of disease is it used?
Does the drug help? Prescribed for the treatment of acute, chronic sinusitis of a bacterial nature. The product is effective against other pathogens, for example, chlamydia, mycoplasma. Recommended during the recovery period after surgery to prevent complications. It is combined with other drugs, which is useful for unspecified etiology of sinusitis of any severity.
Josamycin has virtually no effect on enterobacteria, so even with prolonged therapy it does not inhibit the functioning of the gastrointestinal tract.
The instructions for using Nazoferon can be found by clicking on the link.
Vilprafen
Antimicrobial drug from the macrolide group. The main active ingredient is josamycin. Available in the form of tablets with a dosage of 500 mg .
The drug is active against Chlamydia, Mycoplasma, Ureaplasma, Staphylococcus, Corynebacterium, Neisseria, Peptostreptococcus, Clostridium, Treponema. In therapeutic doses it acts bacteriostatically. As the concentration increases in the affected tissues, the bactericidal effect of josamycin appears.
Vilprafen is quickly absorbed by the gastrointestinal mucosa. Penetrates well into all organs, tissues and body fluids (except the brain). It creates high concentrations of the drug there, which retain their activity for a long time. The highest concentrations are observed in lung tissue.
The drug is metabolized in the liver to form weakly active metabolites. It is excreted from the body mainly with bile.
Indications for use
Various infectious and inflammatory diseases caused by microorganisms sensitive to this type of antibiotic, including eye and dental diseases.
Contraindications
- Macrolide intolerance.
- Liver dysfunction.
- Children weighing less than 10 kg.
- Pregnancy and lactation period.
For people taking xanthines and cardiac glycosides, Vilprafen is prescribed only after consultation with a cardiologist.
Side effects
In rare cases, the use of josamycin leads to the development of the following conditions:
- Disturbances in the gastrointestinal tract (nausea, vomiting, diarrhea).
- Allergy.
- Stagnation of bile.
- Dose-dependent, temporary hearing impairment.
Dosage for adults and how to take antibiotics correctly - detailed instructions
The product is used for oral administration before meals; the tablets should not be chewed. Recommended dosages:
- for the treatment of any form of the disease for adults and children over 14 years of age - take 500 mg twice a day, 500 mg once a day after a week of therapy;
- for newborns and children under 14 years of age - 30-50 mg/kg per day, the volume of medication is divided into three doses.
You can prepare a suspension from Vilprafen tablets at home, which is often used to treat sinusitis in childhood. The average duration of therapy is 10 days.
Instructions for use
Vilprafen is taken in the recommended daily dose for adults and adolescents over 14 years of age, which is 1-2 g, in 2-3 doses. If necessary, the dose can be increased to 3 g per day. Children aged 1 year have an average body weight of 10 kg.
The daily dose for children weighing at least 10 kg is prescribed based on the calculation of 40-50 mg/kg body weight daily, divided into 2-3 doses:
- children weighing 10-20 kg are prescribed 250-500 mg (1/4-1/2 tablet dissolved in water) 2 times a day;
- children weighing 20-40 kg are prescribed 500-1000 mg (1/2-1 tablet dissolved in water) 2 times a day;
- children weighing more than 40 kg - 1000 mg (1 tablet) 2 times a day.
Typically, the duration of treatment is determined by the doctor and ranges from 5 to 21 days, depending on the nature and severity of the infection. In accordance with WHO recommendations, the duration of treatment for streptococcal tonsillitis should be at least 10 days.
In anti-Helicobacter therapy regimens, Vilprafen is prescribed in a dose of 1 g 2 times a day for 7-14 days in combination with other drugs in their standard doses:
- famotidine 40 mg per day or ranitidine 150 mg 2 times a day josamycin 1 g 2 times a day metronidazole 500 mg 2 times a day;
- omeprazole 20 mg (or lansoprazole 30 mg, or pantoprazole 40 mg, or esomeprazole 20 mg, or rabeprazole 20 mg) 2 times a day amoxicillin 1 g 2 times a day josamycin 1 g 2 times a day;
- omeprazole 20 mg (or lansoprazole 30 mg, or pantoprazole 40 mg, or esomeprazole 20 mg, or rabeprazole 20 mg) 2 times a day amoxicillin 1 g 2 times a day josamycin 1 g 2 times a day tripotassium bismuth dicitrate 240 mg 2 times a day day;
- famotidine 40 mg per day furazolidone 100 mg 2 times a day josamycin 1 g 2 times a day bismuth tripotassium dicitrate 240 mg 2 times a day).
In the presence of atrophy of the gastric mucosa with achlorhydria, confirmed by pH-metry: amoxicillin 1 g 2 times a day josamycin 1 g 2 times a day bismuth tripotassium dicitrate 240 mg 2 times a day.
For common and globular acne, it is recommended to prescribe Vilprafen at a dose of 500 mg 2 times a day for the first 2-4 weeks, then 500 mg of josamycin 1 time a day as maintenance treatment for 8 weeks.
The instructions for Vilprafen Solutab stipulate that the drug can be taken in different ways: you can take the tablet with water, or before dissolving it in 20 ml of water. The suspension that forms after dissolving the tablet must be mixed very thoroughly.
Vilprafen tablets must be swallowed whole. Often patients are interested in how to take it, before or after meals. The instructions indicate that the tablets must be swallowed between main meals.
When treating, it should be taken into account that if one dose is missed, you must immediately take a dose of the drug. However, if it is time for your next dose, do not take the missed dose and return to your normal treatment regimen. Do not take double dose. A break in treatment or premature discontinuation of the drug reduces the likelihood of success of therapy.
Advantages of treatment with Vilprafen, price and analogues
Josamycin is one of the best for the treatment of chronic and complicated forms of sinusitis. It has a wide spectrum of action and practically does not cause side effects. Suitable for replacing another antimicrobial drug during long-term therapy. The average cost is 570 or 740 rubles, depending on the dosage.
There are no similar drugs on the market based on this antibiotic. Some doctors prescribe azithromycin-based products (for example, Sumamed) as an alternative. However, they have other pharmacological properties, restrictions on use and pronounced drug interactions (with antacids, macrolides, heparin).
Medicines and analogues should be prescribed by the attending physician based on diagnostic results, age and clinical manifestations.
conclusions
- Vilprafen Solutab is a modern antimicrobial drug based on josamycin.
- The product is produced in the form of tablets with a dosage of 500 and 1000 mg. They can be used to prepare a suspension for children.
- Active against most bacteria and pathogens - chlamydia, mycoplasma. Does not affect enterobacteria.
- Has a wide range of applications. Suitable for the treatment of infectious sinusitis, for the prevention of complications after surgery.
- The product is well tolerated by the body. Rarely causes adverse reactions and does not inhibit intestinal microflora.
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general information
Urogenital infections cause serious harm to the life of the baby and mother. Therefore, pregnancy is not an obstacle to prescribing antibiotics.
As the baby passes through the birth canal, he becomes infected with infections from the mother. Which leads to various pathologies in newborns.
Before taking any medication during pregnancy, you must not only consult with your doctor, but also read the instructions for use of the medication yourself (carefully study the indications, dosage, side effects and contraindications).
It is not recommended to take the antibiotic Vilprafen for pregnant women who have kidney pathologies or are hypersensitive to the active substances of the drug.
Vilprafen should not be taken by pregnant women with kidney pathologies.
Possible side effects after taking Vilprafen:
- Vomit,
- Nausea,
- Impaired functioning of the liver and kidneys,
- Severe abdominal pain (general stomach upset),
- Allergic rash on the body,
- Visual and hearing impairment
- Weakness,
- Malaise,
- Increase in body temperature to 40 degrees.
General information about the drug
Vilprafen has been prescribed by doctors for a long time for inflammatory processes in the maxillary sinuses. Characteristics and general data:
- Refers to antibiotics.
- The active substance is josamycin.
- The content of the active substance in one tablet is 1000 milligrams.
- Available in several forms.
- Has minimal impact on the microflora of the body.
- Effective in eliminating gram-negative and gram-positive microorganisms.
- Reduces inflammation in the maxillary sinuses.
- Not addictive.
- There are restrictions when taken together with a number of drugs.
- There is no drug withdrawal syndrome.
- Restores the functioning of the respiratory system after the negative influence of microbes.
IMPORTANT! The use of antibiotics is more effective in the treatment of bacterial sinusitis.
Vilprafen or Vilprafen Solutab - which is better?
Many people wonder which is better: Vilprafen or Vilprafen Solutab. To answer this, you should take a closer look at the differences.
Both drugs have a common active ingredient - josamycin and almost the same name. However, this does not mean that they are completely identical. There are two main differences:
- Amount of active substance . Regular tablets contain 500 grams of josamycin, and in Solutab this number is doubled and is 1000 grams. Therefore, this fact must be taken into account when calculating the dosage and duration of therapy.
- Solutab tablets are available in the form of tablets that are easily dissolved in liquid . Thus, they can be easily diluted in a glass of water and drunk, which greatly simplifies use. They are better absorbed and provide high acid resistance.
Both medications are available in tablet form and are manufactured in Holland. The price of these tablets reaches 550-600 rubles, when regular Vilprafen costs about 500 rubles. Therefore, purchasing a product with a double dose of josamycin is almost 30% more profitable.
Prescription of Vilprafen for sinusitis
The remedy is not the primary use for sinusitis. Doctors recommend switching to this drug if the body has a negative reaction or if drugs from the group of penicillins and cephalosporins are ineffective.
At the first signs of allergic reactions to antibiotics of this group, a specialist may prescribe Vilprafen. If sinusitis is of bacterial origin, the action of the medication will be most effective. The ability of the drug to accumulate at the site of infection and a high permeability rate ensures a speedy recovery of the patient.
You should refuse to take it under the following conditions:
- Individual intolerance to the active substance.
- Presence of problems in the functioning of the liver and biliary tract.
- Age restrictions. Tablets are prohibited for children under five years of age, and suspensions for children under three months of age.
In rare cases, the drug is prescribed to pregnant women. The main condition is that the risk is justified when it is impossible to do without taking an antibiotic.
The product is not recommended for consumption during breastfeeding. If necessary, breastfeeding is suspended during the period of administration.
Recommendations for taking the drug
There are a general number of rules when taking antibiotics:
- You should strictly adhere to the doctor’s prescriptions and use the drug in the recommended dosage;
- classic antibiotics are taken two to three times a day, with equal intervals between doses;
- medications are taken between meals;
- Do not chew the drug, swallow it whole with water;
- the suspension is suitable for use within four weeks from the moment the package is opened;
- if you have diabetes mellitus, you should pay attention to the sugar content in the suspension;
- You need to take the drug before the end of the course, even if the symptoms of the disease are eliminated before the official end of taking the antibiotic.
Features of the use of Vilprafen
Vilprafen, like other antibiotics, should only be prescribed by a doctor in the presence of a bacterial infection. For effective treatment with the drug, you should follow the general recommendations:
- Before you start taking the drug, you must read the instructions for it, and if you have any questions, you should contact your doctor for clarification;
- you must strictly adhere to the prescribed doses, dosage regimen and duration of treatment;
- Usually the antibiotic is taken 2-3 times a day, and equal time intervals between doses should be maintained to achieve a constant content of the drug in the body;
- the drug is given between meals;
- The coated tablets are swallowed whole and washed down with water;
- dispersible tablets can be swallowed whole and washed down with liquid, or can be diluted in water before use (at least 20 ml);
- shake the suspension before use and measure out the required amount using the measuring cup provided in the package;
- after opening the bottle, the suspension can be used for no more than 4 weeks;
- if severe diarrhea occurs, you should consult a doctor, as this may be a manifestation of pseudomembranous colitis, which cannot be treated at home;
- patients with diabetes should take into account the sucrose content in the suspension;
- Vilprafen Solutab contains aspartame, which should be taken into account in patients with phenylketonuria;
- Treatment with the drug must be continued until the entire course is completed, even in the absence of symptoms of the disease.
Dosage of the drug for sinusitis
Patients with inflammation of the maxillary sinuses should take the medicine up to three times a day, at a dosage of 500 milligrams of the active substance per tablet. The regimen is recommended for patients with sinusitis in the initial stage of the disease.
In case of acute form, the dosage is increased to 1000 milligrams of josamycin in one tablet.
For patients in the younger age group, the dosage is calculated individually, based on body weight.
The classic course of taking Vilprafen is from seven to ten days.
