How to use Derinat nasal drops

Pharmacological action of the drug

Immunomodulators have a positive effect on cellular and humoral protective immune functions.
In particular, they stimulate the activity of B-lymphocytes and T-helpers, which recognize antigens and produce antibodies to infectious agents that have entered the human body. The medicine activates the nonspecific resistance of the patient’s body. After its administration, the immune response is enhanced, inflammatory processes caused by viruses or bacteria are optimized.

Since the active ingredient, sodium derinate, is characterized by pronounced lymphotropism, the process of detoxification by the lymphatic system is accelerated in patients.

This positive effect allows the drug to be given to those patients whose immunity is significantly reduced due to chemotherapy or after treatment with radiation therapy.

Also, the active components regulate hematopoiesis, that is, they normalize the number of blood cells, affecting not only lymphocytes, but also platelets and phagocytes.

What is Derinat: description. Indications for use

An important task of the drug is to stimulate the regeneration of damaged tissues. In addition, it enhances reparative functions, correcting the functioning of the immune system and increasing the body's resistance.

The composition includes sodium deoxyribonucleate, which, when applied topically, is very quickly absorbed by small capillaries. The lymphatic system then distributes the active substance throughout the body, transporting it to the patient’s organs.

Excretion is carried out mainly by the genitourinary system and kidneys. Partially excreted along with feces.

An immunostimulant solution is prescribed for various diseases. If you take an intranasal form of release for the nose, then monotherapy is aimed at eliminating:

• ARVI (including preventive measures during epidemics);
• Chronic infections of secretory membranes caused by fungi, bacteria, viruses;
• Acute rhinitis, sinusitis, etc.

At the same time, you can take Sinupret, Rinofluimucil or other tablets/liquid substances that relieve inflammation, reduce swelling and remove pathological exudate.

The immunomodulatory mixture is also recommended for pathologies of the eyes and oral cavity. Comprehensive medical care is prescribed for the following pathologies:

• Chronic infections in gynecology;
• Trophic ulcers, gangrene, non-healing wounds;
• Burns, frostbite, necrosis after irradiation;
• Hemorrhoids, gastrointestinal ulcers;
• Oncology, hematopoiesis disorder;
• Pulmonary obstruction, tuberculosis, ischemic heart disease, rheumatoid arthritis, etc.

At what age can an immunomodulator be prescribed? The instructions indicate that it is suitable for treating even newborn babies.

Derinat for children

As doctors' reviews show, the use of Derinat in pediatrics has a positive effect on children's health. But a child is not prescribed the drug without serious reasons. It is used in the treatment of acute respiratory viral infections and for the prevention of influenza.

Derinat for children is often used in the treatment of respiratory diseases caused by infection. These include acute respiratory diseases, pneumonia, bronchitis. In addition, the drug helps well in the treatment of pathologies of the genitourinary system, heart, gastrointestinal tract, central nervous system disorders, arthritis, etc.

To treat inflammation of the respiratory organs, Derinat can be used in the form of inhalations. This method of therapy is used for hay fever, adenoiditis, tonsillitis, and bronchial asthma. The product is diluted with saline solution, take 1 ml of liquid. Inhalations are done twice a day. The course of therapy lasts 5-10 procedures.

Since Derinat can have negative effects on a young child’s body, you should consult a pediatrician before purchasing the drug. Basically, the drug is prescribed with caution and after it has been accurately determined that the child does not have individual intolerance. In addition, allergic reactions in children to the active substance may be more severe than in adults. In such cases, Derinat will not be safe.

Any medicine can cause allergies. Most often it manifests itself in the form of a skin rash and biological wetting of the epithelium. The allergic reaction sometimes spreads to large areas of the skin. It is quite difficult to cure the consequences in a child, which is why before prescribing Derinat, the pediatrician must accurately determine whether he has any contraindications to the use of an immunomodulatory drug.

Release form of the drug

The drug has a transparent composition, without any shades or foreign inclusions. It is produced in several forms:

• In bottles for intramuscular injections of 2 and 5 ml;
• In bottles for local or external use. Packaged in containers of 10 and 20 ml. The jars are equipped with a dropper or sprayer. There are also glass vials without additional devices for administration into the nose/mouth or eyes.

Derinat photo
Excipients are sodium chloride and water for injection.

General description of the medication

What does the instructions for use say about the drug "Derinat" (spray)? The abstract says that the active ingredient of the drug is sodium deoxyribonucleate. There are 10 milligrams in 1 milliliter. In addition, there are additional components such as sodium chloride. They provide the drug with the required consistency and concentration.

The medicine is available in the form of a solution for intramuscular administration, a product for nasal administration and a composition with a nebulizer. The consumer can choose the form of medication that suits him best.

Directions for use and dosage for adults

Your doctor will tell you how to administer an immunomodulating solution. The instructions indicate that when applied externally or locally, the number of drops and method of use depend on the location of the focus of pathological changes.

The dosage is almost the same for both children and adults. The duration of the course is selected depending on the severity of the pathology. Prevention of ARVI It is recommended to use antiviral nasal drops up to four times a day. Inject 2 drops into each nasal passage. During epidemics, it is enough to carry out preventive measures for 7-14 days. If during the process of therapeutic manipulations the patient still exhibits symptoms of ARVI, then the number of drops is increased to 3, and the frequency of physiatric manipulations is reduced to one hour, but only for the first day. Then they move on to the standard dosage regimen - up to 4 times a day. Course duration is 5-30 days. Diseases of the paranasal sinuses To relieve the pathological process in the paranasal cavities and on the mucous membranes of the nose, 3-5 drops of liquid are instilled into each nostril. The administration can be repeated 4-6 times per day. The therapeutic course is continued for one to two weeks. Inflammation of the oral cavity Immunocorrector is used as a mouth rinse. One bottle is divided into 2-3 uses. You can rinse your mouth up to six times a day. The duration of the course of treatment is 5-10 days. Ophthalmology If the patient's eyes become inflamed or dystrophic changes appear, the substance is instilled up to three times a day. 1-2 drops are dropped into each eye. Medical care is continued from two weeks to one and a half months.

For adults, immunocorrector therapy is also recommended for more serious pathological changes. It helps regenerate tissue in case of hemorrhoids, necrosis, and infectious lesions in the gynecological area. In each case, the drug is used differently. If a woman has a fungal or bacterial infection or foreign microorganisms of another type in her reproductive system, the solution is recommended for intravaginal irrigation or tamponade.

One procedure requires a bottle with a capacity of 5 ml. Treatment is continued for up to two weeks 1-2 times a day.

Microenemas help with hemorrhoids. To do this, 15-40 ml of medication is poured into the rectum for up to 10 days.

Necrosis of the skin or secretory membranes, non-healing wounds, trophic ulcers can also be cured if systemic care includes an immunostimulant. It is applied with application bandages to the affected areas. Can also be sprayed onto wound surfaces. Physiatry is carried out 4-5 times a day, up to 40 ml of the substance. The course lasts 1-3 months.

The shelf life after opening the ampoule is no more than 14 days. After this time, the solution may lose its properties.

Derinat drops during pregnancy

To prevent the fertilized egg from being rejected, women's immunity is specifically reduced after conception. That is why during pregnancy chronic diseases often worsen, infection with pathogenic microorganisms, etc. occurs more often. Can Derinat be used in the nose by women preparing to become a mother?

The instructions say that this is contraindicated. Why? As already mentioned, the fetus remains in the reproductive system only because immune cells reduce activity and do not perceive it as a foreign body. The task of the immunomodulator is to increase immunity, that is, to reduce the risk of miscarriage in the early stages.

In the 1st trimester of pregnancy, it is especially dangerous to take immunomodulatory drugs, since the fetus has not yet attached to the walls of the uterus and becomes vulnerable to the protective function of the lymphatic system. But in the 2nd and 3rd trimester, this threat decreases, and they can be taken, but only after consulting a doctor.

Test samples are recommended for pregnant women. Start with one drop of intranasal manipulation. If no negative reactions are observed and no complications appear, then you can safely use the immunomodulator to eliminate infectious foci.

When breastfeeding (breastfeeding), it is also necessary to consult a pediatrician. During lactation, sodium desixoribonucleate is absorbed into all organs of a woman, including milk. When breastfeeding, your doctor will be able to select an individual therapeutic regimen.

Use during pregnancy and breastfeeding

The manufacturer does not indicate any restrictions on the use of the drug either while carrying a baby or while breastfeeding. This is explained by the fact that its composition is safe, and local use does not allow it to achieve a general effect on the body and its immune system as a whole. There have been no reports of side effects or negative effects during pregnancy (especially in the 1st trimester) or on the baby during feeding. Despite this, you should still use the product only after permission and advice from a doctor.

It is believed that the use of a spray as a preventive product for women who are susceptible to inflammatory diseases of the upper respiratory tract is preferable to suffering from infection and undergoing intensive therapy with antibiotic drugs. The use of Derinat in the early stages of disease development helps in the future to significantly reduce the list of drugs necessary for therapy.

Derinat nasal drops for children

The instructions say that the drug can be prescribed for newborns from the first year of life. The action is aimed at increasing immunity, so pediatricians most often recommend an immunomodulator for children under one year of age or older who are prone to frequent colds.

Studies have shown that any dosage form is well tolerated by young patients. Derinat for children has virtually no contraindications and is indicated in alleviating many diseases associated with inflammatory reactions in the secretory epithelium. Undesirable side effects occur very rarely.

Drops for children that contain sodium deoxyribonucleate are prescribed for the following diseases:

1

Respiratory tract infections (rhinitis, sinusitis). For preventive purposes, 1-3 drops are instilled into each nostril for the child. In case of infection with viruses or bacterial damage to tissues, the amount of product is increased to 5 drops. On the first day of symptoms, the active ingredient is instilled every hour and a half.

2

For adenoids and complex sinusitis. The best method of physiatry is tamponade. Cotton swabs moistened with the composition are suitable for this. The procedure is repeated 6 times per day.

3

Ophthalmological pathologies. Instill 1-2 drops of the product three times a day. It is recommended to pull back the eyelid so that the active component enters the conjunctival sac.

4

Problems in the oral cavity. Carry out rinsing. If the child is still small and cannot carry out such a procedure on his own, then his mucous membranes are treated with gauze moistened with medicinal liquid. Repeat several times a day.

Dr. Komarovsky does not recommend taking immunocorrectors on your own, much less giving them to a child without consulting a doctor. It is imperative to establish the exact dosage, frequency of administration and course duration.

It is important to remember that even the most harmless medications can have side effects in children. For example, it happens that an allergy to Derinat occurs. That is why you should be very careful about the pediatrician’s instructions.

What is Derinat spray used for?

An immunomodulatory spray can be used to treat inflammatory processes and to prevent them, which is especially important for children who attend institutions with a large number of other people (kindergartens, schools, etc.). It is worth noting that in addition to being used for the nasal cavities and throat, the product can be used in gynecology, for trophic ulcers, and for skin lesions caused by high or low temperatures.

Indications for use in the nose

Typically, the spray is used as an element of complex therapy, since it has only a local effect, which is simply not enough for many diseases. Spraying into the nasal cavity is important for diseases of the upper respiratory tract in acute and chronic form to eliminate rhinitis, as well as all forms of sinusitis. The product can be used for both treatment and preventive purposes.

For sinusitis and other inflammatory processes in the nasal cavities, this product helps solve several important problems at once:

• helps restore local immunity for a long time;
• fights pathogenic microorganisms;
• helps relieve swelling and inflammation of the mucous lining;
• promotes the removal of purulent exudate.

Use to treat throat

The spray can also be sprayed into the throat area, and here most often it acts as a means of monotherapy. Here its use is advisable for the treatment and prevention of acute respiratory viral infections, as well as the elimination of various inflammatory processes localized in the mouth and throat (nasopharyngitis, sore throat, etc.).

In addition, the remedy can also be successfully used for adenoids in children. It is worth noting that the drug can be used as an independent drug only if early therapy is started before the development of severe symptoms - this way it will be possible to completely avoid reaching the peak of poor health. If there are developed manifestations or even complications, then it is necessary to use additional means based on the source of the problem, for example, antibacterial drugs.

Derinat for infants and newborns

The immunomodulatory agent is indicated for children from the first day of life. The frequency of administration does not differ from adult prescriptions. The single dose varies depending on age. So, for intramuscular injections, the following scheme is recommended:

• For infants under two years old - no more than 0.5 ml;
• For children 2-10 years of age, increase the dose to 4 ml;
• Children over ten years old – 5 ml.

External and local use of natural proteins does not differ from the instructions for adult patients.
For infants, the medicinal composition is also instilled into the nasal passages, 2 drops up to 4 times per week for a runny nose and ARVI. If there are pathological changes in the oral cavity, then rinses are performed. Skin lesions and non-healing wounds are treated by spraying the product or applying prepared applications.

Inhalations

The drug can be sprayed by pouring the specified dosage into the nebulizer. This method helps especially well with frequent penetration of pathogenic microorganisms into the respiratory system.

Inhalations are generally recommended for people with the following ailments:

• Tonsillitis;
• Adenoids;
• Bronchial asthma;
• Allergic reactions, hay fever.

Not pure liquid from the ampoule is poured into the nebulizer, but mixed with saline solution in a ratio of 1:4. During one procedure, you should inhale the healing aerosol for 5 minutes. Repeat twice a day. The course of therapy should consist of 10 inhalations, that is, five days.

Derinat eye drops

The immunocorrective protein has a beneficial effect on the mucous membranes of the eyeballs. It is prescribed for various diseases:

• Herpetic keratitis;
• Computer myopia;
• Asthenopia;
• Primary glaucoma;
• Chronic uveitis.

The substance is delivered to the conjunctival sac three times a day. 1-2 drops of solution are injected into one eye. Duration of treatment is 2-6 weeks. It is not recommended to use simultaneously with ophthalmic substances containing metal salts.

What is better Derinat or Grippferon?

Often people who want to protect themselves from viral agents are looking for the most effective way to combat ARVI and its prevention. If we compare Derinat with Grippferon, then it is impossible to answer unequivocally which is better. Why?

Both drugs have an immunomodulatory effect, have an antiviral effect, and also relieve inflammatory changes. Biologically active immunocorrector proteins are responsible for such functions.

But unlike Grippferon, the first version of the immunostimulant is produced not only for topical use, but also in the form of injections for intramuscular injections. In fact, this suggests that it belongs to medications with a wider spectrum of action.

What are the indications?

In what situations should you use the drug "Derinat" (spray)? The instructions for use indicate that there are certain indications. They are listed in the annotation. Please study them carefully before starting the correction course. Such situations include:

• respiratory viral diseases, including influenza;
• prevention of colds;
• dystrophic eye diseases;
• damage by microbes and viruses to the oral mucosa;
• in gynecology it is used to treat bacterial and fungal infections (in combination with other drugs);
• to eliminate infection and inflammation of the respiratory tract;
• gangrene and ulcers of the lower and upper extremities;
• hemorrhoids, frostbite and some skin problems.

The medication for internal administration is also used for other indications. However, this article tells you about Derinat spray. Instructions for use for children and adults provide for use only in the situations described above.

How much does Derinat cost in a pharmacy? Price

The cost of the drug is:

Reviews

These drops are good because they can be used not only for treatment, but also for the prevention of ARVI. To do this, they are dripped according to the scheme of 2 drops 3 times a day for one to two weeks.

But if you have already felt the symptoms of a cold, then you need to instill 2-3 drops every 2 hours on the first day you get sick. And then two or three drops 3 times a day. Available in pharmacies without a prescription, they are suitable even for infants. A very good product to support your immune system. Galina

, 32 years

My son had been sick with a runny nose for a month, and the pharmacist at the pharmacy suggested trying these drops. They recovered relatively quickly, it turns out that they only treat the symptoms, but also activate the immune system.

Of course, they can be used as a prophylactic against acute respiratory infections and acute respiratory viral infections. It is better to take those with a dropper bottle (like Pinosol), otherwise you may need a pipette for instillation. Also pay attention to the fact that there is a hologram on the packaging. Svetlana

, 40 years

We use it as an immunomodulator for a child during the cold season from October to March, when there is a high probability of catching a cold. We prefer a bottle with a dropper; it is more convenient to use, but a little more expensive. Before that, I used it myself, when my son was six months old - he got the flu. The doctor recommended Derinat as an addition to treatment. She recovered quite quickly, maintaining lactation. Alla

, 28 years

No matter how much I use Derinat for a runny nose, for some reason it doesn’t help me. Doctors praise it, there are a lot of positive reviews about it, but for me it is completely useless. I took several courses of treatment for colds, but did not feel any effect.

It is possible that my body simply does not perceive its healing properties. A placebo of sorts. For colds, I prefer IRS-19; it is a similar analogue of Derinat, as the pharmacy explained to me. Anna

, 38 years

Side effects and overdose

Derinat spray is considered a safe drug, so there have been no cases of overdose or side effects when used correctly. In a situation with a spray, it is very difficult to overdose on the product, since the bottle dispenses a clearly dosed amount of the drug.

It is worth noting that combining this product with other drugs in the treatment of colds and flu only increases the therapeutic effect and significantly reduces the duration of recovery. In addition, the spray also makes it possible to reduce the dosage of antibiotics and antiviral drugs used. Considering all this, it is obvious that the product is available in pharmacies without a prescription.