Pharmacodynamics and pharmacokinetics
The medicine has analgesic, antitussive, sedative, vasoconstrictor, antipyretic, bronchodilator, antihistamine effects, and can reduce the severity of symptoms of colds and acute respiratory diseases
.
Under the influence of phenylephrine hydrochloride, hyperemia of the mucous membranes of the nasopharynx, nasal cavity, paranasal sinuses, local exudative manifestations decreases, swelling decreases, and the lumen of blood vessels narrows.
Pheniramine maleate has antihistamine, antiserotonin, sedative, weakly anticholinergic effects, and is a blocker of H1-histamine receptors. Under the influence of the substance, swelling and hyperemia of the mucous membranes
, the lumen of blood vessels narrows, the severity decreases, rhinorrhea, itching of the nose and eyes are suppressed.
Paracetamol is a non-narcotic analgesic, has anti-inflammatory (weakly expressed), antipyretic, analgesic effects.
Theraflu begins to act 20 minutes after taking the solution, the duration of exposure is up to 4.5 hours.
Theraflu powder: description and compatibility with antibiotics
The symptoms of colds cause discomfort to a person.
Moreover, it forces a person to change his usual way and rhythm of life.
A constant runny nose, malaise, muscle pain, painful cough, sore throat, fever - a person has to struggle with all these manifestations.
There are plenty of methods and medications, both for local use and oral administration, that can eliminate unpleasant symptoms. One of the most effective medications in the fight against flu and colds is Teraflu powder.
On the modern pharmacological market, anti-cold medications are presented in a huge range. One of the most effective and inexpensive medicines is Theraflu. This product is a combination product.
From the instructions it is clear that the medication has powerful analgesic, antipyretic and vasoconstrictor properties. The medicine helps to alleviate and minimize the symptoms of not only colds and flu, but also sore throats.
The drug has many analogues, first of all, these are drugs with the same name: Teraflu Extra, Teraflu Bro, Teraflu Lar.
The actions of these funds are somewhat different. For example, Theraflu Bro is indicated for the treatment of bronchitis, and Theraflu Lar is indicated for the treatment of sore throat and laryngitis. Cheaper analogues of the drug include Rinza, Coldrex, Fervex.
Any of the listed medications can be purchased both at a pharmacy and in an online store. Products are dispensed without a doctor's prescription. The average price of Teraflu powder No. 4 is 170 rubles.
The drug is available in powder form in sachets for preparing a solution for internal use. The powder has a pinkish, gray-violet or white color, and the taste of lemon or wild berries.
The medicine contains the following active ingredients: paracetamol, phenylephrine hydrochloride, pheniramine maleate. In addition, the product is equipped with additional substances: calcium phosphate, sodium citrate dihydrate, magnesium stearate, sucrose, acesulfame potassium, silicon dioxide, citric acid, flavorings and dyes.
The product is very effective, but it can only be used with a doctor’s prescription. You should not ask friends for advice or rely on reviews on the Internet. The medicine can only be prescribed by a qualified specialist. When selecting a medication, he takes into account the individual characteristics of the body, the course of the disease and the general condition.
A drug is prescribed for the treatment of sinusitis, rhinorrhea, flu, colds, allergic rhinitis, nasopharyngitis, hay fever, and vasomotor rhinitis.
Theraflu in powder form is effective for:
- high temperature;
- swelling;
- painful sensations in the throat;
- joint pain;
- runny nose;
- nasal congestion;
- headaches.
From the annotation to the product, the following properties of the medication are known:
- antitussives;
- sedatives;
- antipyretics;
- vasoconstrictors;
- antihistamines;
- decongestants;
- bronchodilators;
- anti-inflammatory;
- analgesic.
Regular use of the drug (a course of no more than a week) helps to minimize the severity of symptoms of colds and acute respiratory viral infections.
Due to the presence of phenylephrine hydrochloride in the product, the medicine promotes:
- narrowing of the vascular lumen;
- reducing hyperemia of the nasopharyngeal mucosa;
- minimizing exudative manifestations;
- reducing swelling.
Pheniramine maleate helps in narrowing the lumen of blood vessels, reducing the severity of allergic manifestations, suppressing sneezing, itching of the nose and eyes, as well as rhinorrhea. As for paracetamol, this substance is a non-narcotic analgesic.
The therapeutic effect after taking the drug occurs after approximately twenty minutes. The duration of exposure to the drug is 4.5 hours.
Theraflu powder is a product for internal use. First, the contents of one sachet must be diluted in 200 ml of boiled, slightly cooled water. To improve the taste, the drink can be sweetened.
Adults are prescribed to take the contents of one sachet three times a day. The maximum daily dosage is three sachets. The interval between use of the solution is 4 hours.
You can take the medicine at any time of the day. The maximum therapeutic effect of the drug is observed in the evening. The duration of treatment with Theraflu is a week. Taking the medicine for more than the specified period, in excess dosage, is fraught with overdose and side effects. If after three days after the start of therapy the condition does not improve, you should consult a specialist.
The product is not recommended for use during pregnancy. Theraflu in this form is not prescribed to children under twelve years of age.
This antiviral medication can be used to treat colds in children, but only in those over 12 years of age.
The contents of one sachet are prescribed to be consumed three times a day.
Maximum course duration is a week.
You should not consume more than three sachets per day. You should not take this medication if you are pregnant or breastfeeding.
Many people are interested in the combination of Theraflu and antibiotics, whether compatibility of such drugs is possible or not. It should be understood that antibacterial agents are medications whose action is aimed at inhibiting the growth of bacteria and eliminating them.
As for Theraflu, it is an antiviral drug that helps eliminate the manifestations of diseases of a viral nature, in particular ARVI and influenza. Only a doctor can combine the use of Theraflu and antibiotics, and only if the pathology is bacterial in nature.
If the pathology is viral or inflammatory in nature, the body is able to independently overcome the viral infection. In principle, most antibacterial agents can be used together with Theraflu. But for this there must be evidence.
As for contraindications to the treatment of acute respiratory viral infections, colds or flu with Theraflu, the drug is not recommended for people with:
- individual intolerance;
- diseases of the cardiovascular system;
- diabetes mellitus;
- chronic bronchitis;
- emphysema;
- pathologies of the thyroid gland;
- blood diseases;
- glaucoma (angle-closure form);
- hyperbilirubinemia;
- prostate adenoma;
- asthma;
- pheochromocytoma;
- hypertension;
- atherosclerosis;
- renal and liver failure.
In addition, the drug is contraindicated for use not only by children under 12 years of age, pregnant and breastfeeding women, but also by the elderly.
The drug should not be combined with Furazolidone and MAO inhibitors (provoke the appearance of hypertensive crisis and agitation), glucocorticosteroids (fraught with the development of glaucoma), antidepressants (provoke the appearance of stool disorders, xerostomia).
You should not take any medications without your doctor’s knowledge or combine Theraflu with antibiotics or the above medications.
Exceeding the indicated dosages, as well as abuse of Theraflu, is fraught with:
- allergic reactions: rash, itching, angioedema;
- increased excitability;
- drowsiness;
- dizziness;
- pain in the epigastrium;
- xerostomia;
- nausea;
- vomiting;
- increased heart rate;
- increase in blood pressure;
- urinary retention.
During the therapeutic course, it is necessary to avoid alcohol consumption.
Theraflu and antibiotics - compatibility of medications is possible only if indicated, and only with a doctor’s prescription.
There are many analogues of Theraflu. You can replace this medication: Teraflu Lar, Teraflu Extra, Teraflu Extratab, cheaper drugs - Fervex, Coldact, Coldrex, Rinza.
The average price of Theraflu powder for one sachet is 40 rubles. The cost of package No. 10 is 400 rubles.
Cost of analogues:
- Teraflu Lar - 150 rubles;
- Theraflu Extratab - 170 rubles;
- Theraflu lozenges - 200 rubles;
- Koldakta - 200 rubles;
- Fervexa - 300 rubles;
- Rinses - 320 rubles.
Source: https://gajmorit.com/gripp/teraflju-poroshok/
Theraflu price, where to buy
The price for 1 sachet of Theraflu ranges from 30 to 50 rubles.
A package of 10 sachets costs about 370 rubles.
- Online pharmacies in Russia Russia
- Online pharmacies in Ukraine Ukraine
- Online pharmacies in Kazakhstan Kazakhstan
ZdravCity
- TheraFlu Theraflu LAR spray against viruses and sore throat, spray, 30ml Novartis Consumer Health
TheraFlu Theraflu for colds and flu, powder, lemon flavor, 4 sachets Famar France
TheraFlu Theraflu LAR menthol against viruses and sore throat, tablets, 20 pcs. Novartis Urunleri
TheraFlu Theraflu Extratab for colds and flu, tablets, 10 pcs. Novartis Urunleri
TheraFlu Theraflu for colds and flu, powder, wild berry flavor, 10 sachets GSK Consumer Health Inc.
Pharmacy Dialogue
- Theraflu sachets No. 4 (Lemon) Famar L»Aigle
Theraflu Lar tablets d/diss. No. 20 (Menthol) Novartis
Theraflu Lar tablets No. 16 Novartis
A cold is usually a disease in which the following symptoms are observed: runny nose, cough, sore throat. It is believed that a cold can go away on its own, even without treatment. But it is not always the case. If you don't take medicine, some types of “colds” are not so easy to get rid of.
What diseases are classified as colds? By cold, people usually mean acute respiratory viral and bacterial infections, influenza and, sometimes, herpes rashes on the lips.
Causes of the common cold
What makes you sick? Why do we get colds? There are several reasons:
- Colds are generally very contagious (highly contagious);
- Weak immunity. If the immune system is not able to quickly suppress the infection, then the disease progresses quickly;
- Hypothermia and stress often contribute to the onset of a cold.
Main symptoms of a cold
- Fever;
- Cough;
- Runny nose;
- A sore throat;
- Headache;
- Hoarse voice;
- Muscle and joint pain;
- Weakness, loss of strength;
- Redness of the eyes.
A combination of several of these symptoms most likely means you have a cold. It happens that the onset of the disease is similar to a common cold, and then additional symptoms appear:
- A rash or petechiae appears (small dark red spots, 1-2 millimeters in diameter);
- The lymph nodes in the neck become inflamed;
- On examination, white plaques are noticeable on the tonsils.
These symptoms indicate that the disease may be quite serious, and without delay, it is necessary to consult a specialist for a diagnosis and recommendations for treatment.
Cold medicines
Photo: Boiarkina Marina/Shutterstock.com
Since the course of a cold can vary, there is no universal cure for a cold. Basically, medications are divided into two groups:
- Antiviral agents;
- Symptomatic remedies.
When ARVI is complicated by a bacterial infection, antibiotics are prescribed.
Antiviral medications for colds
A cold never comes on time, but there are times when you can’t get sick at all and you need to get better as quickly as possible. How, in this case, can you quickly cure a cold? Firstly, antiviral drugs will help you cope with a cold faster. There is no need to wait for the disease to gain full strength; take antiviral medications at the first sign of a cold. The drug “Ocillococcinum” gives good results not only in adults, but also in children. The sooner you start treatment, the faster you will see the result: the cold will go away much faster. How do antivirals work for colds? On the one hand, these drugs help your own immunity fight infection, and on the other hand, they themselves have an effect on the virus that has entered the body.
There are a number of drugs that have a targeted effect and are effective only against a specific type of virus. For example, this can be said about anti-influenza drugs,
which include:
- Tamiflu;
- Relenza;
- Remantadine and others
These drugs are prescribed mainly for the treatment of influenza types A and B, and are ineffective for the common cold.
Interferon for colds
Sometimes, if there are signs of a cold, medications containing interferon are prescribed. Interferon is a protein that a cell produces in response to an invading virus to prevent it from replicating. Thus, the effect of drugs containing interferon is based on its ability to prevent the proliferation of viruses and stimulate the immune system to fight viruses. Preparations containing interferon are used to treat various viral diseases, not just colds.
Pharmacies offer a wide range of interferon-containing over-the-counter drugs: drops, ointments, gels, suppositories for colds, for use in ARVI and influenza. The effect of these drugs has not been proven, therefore in Western Europe and North America such drugs are not used as medicines for colds.
Fever and antipyretics for colds
Photo: sirtravelalot/Shutterstock.com
Normal body temperature when measured in the armpit is considered to be 36.6 degrees Celsius. It is known that during the day the temperature can fluctuate between 0.5 and 1 degree. With a cold, the temperature usually rises, and this is due to the fact that microbes, when they enter the body, release toxins (poisons), which cause a reaction that triggers the production of specific substances, which, in turn, act on the temperature center of the brain.
In medicine, there is a special term for high temperature - fever. Fever always develops according to a certain scenario and has 3 stages: an increase in temperature, maintaining an elevated level for some time, and a decrease to the original level. Moreover, the second stage can last several hours or days, or a week.
Fever is a constant symptom of almost all colds.
Depending on the degree of temperature increase, fever is usually divided into:
- Subfebrile - 37.2 - 38.0;
- Low febrile - 38.1 - 39.0;
- High febrile - 39.1 - 40.1;
- Very high febrile (hyperpyrexia) - above 40 degrees Celsius.
Should you lower your temperature if you have a cold?
?
Do not rush to immediately bring down the elevated temperature, give the body the opportunity to turn on its own immunity to protect against infection. If, however, the thermometer shows a mark above 38.5 degrees Celsius, and the patient does not tolerate this temperature well, then you can take an antipyretic drug. Especially high temperatures are dangerous for children, as they can cause convulsions. Therefore, you should always have an antipyretic in your first aid kit:
- Analgesics (paracetamol, phenazone, etc.);
- Non-steroidal anti-inflammatory drugs (acetylsalicylic acid, ibuprofen, etc.)
A brief overview of antipyretic drugs for colds:
- Paracetamol.
- Used to reduce fever in all ages.
- Generally considered safe for children as it is not associated with the risk of Raynaud's syndrome.
- Does not cause stomach irritation.
- Unlike aspirin and ibuprofen, paracetamol does not help reduce inflammation.
- Ibuprofen.
- Has an analgesic and antipyretic effect.
- In children under one year of age, it must be used with a doctor's prescription.
- It should not be used in asthmatic children, chronically ill children, as well as in patients with gastritis and gastrointestinal ulcers.
- Acetylsalicylic acid.
- Widely known under the brand name Aspirin.
- Antipyretic and anti-inflammatory agent.
- Not used in children due to the risk of developing Reye's syndrome.
- Not compatible with alcohol
Sore throat with a cold
When you have a cold, a sore throat is most often associated with the following diseases:
- Pharyngitis (inflammation of the pharyngeal mucosa);
- Sore throat (inflammation of the tonsils and pharyngeal mucosa);
- Laryngitis (inflammation of the larynx).
Treatment for sore throat depends on the cause of the disease. For example, with a sore throat
, treatment with antibiotics is indicated, since this disease is most often caused by bacteria: streptococci and staphylococci.
For pharyngitis
prescribe:
- Gargling (Miramistin, Rotokan, sage, chamomile, eucalyptus, etc.)
- Direct irrigation for sore throat (Hexoral, Tantum Verde, etc.);
- Resorption of throat softening tablets (Gramicidin, Strepsis, Faringosept, etc.).
Cough with a cold
Coughing is a protective reaction of the body aimed at removing exudate, dust, and foreign particles from the respiratory tract. A reflex cough occurs when the pleura is irritated. An important role in the diagnosis of cough is played by accompanying symptoms: the presence of sputum, its color and character, shortness of breath, wheezing.
A cough with a cold can be dry or wet. A wet cough is accompanied by the formation of sputum, which occurs as a result of inflammation of the bronchial mucosa. To treat a wet cough during a cold you need:
- Reduce swelling and inflammation of the mucous membrane;
- Reduce the viscosity of sputum;
- Prevent congestion;
- Restore natural cleansing mechanisms.
Dry cough (without sputum) requires a different approach to treatment, it is necessary:
- Soothe throat irritation;
- Reduce inflammation;
- Reduce the frequency of coughing attacks;
- Convert the cough into a wet form.
The cough may persist for some time, even after all other symptoms of the disease have disappeared.
Runny nose with a cold
A runny nose, or scientifically called rhinitis, is a common and very unpleasant symptom of a cold. Rhinitis is an inflammation of the nasal mucosa. A runny nose during a cold can be of a viral or bacterial nature. Nasal mucus (snot) is released from the nasal passages. Snot is not always a harmless symptom of a cold. Rhinitis can lead to cold complications such as sinusitis, frontal sinusitis, otitis media and some others. Therefore, the treatment of a runny nose, especially in children, should be treated carefully.
To treat a runny nose use:
- Vasoconstrictor drops and sprays (to ease breathing);
- Antibiotic drops and sprays (for bacterial infections);
- Moisturizing sprays and drops (for rinsing and moisturizing the nasal passages);
- Nasal rinsing devices.
Combination drugs for the treatment of colds
There are a number of medicines that are aimed at treating several cold symptoms at the same time. Most often, the manufacturer produces such products in the form of cold powder. The effect of the drug is due to the components included in its composition. Typically this is:
- Ascorbic acid;
- Paracetamol;
- Phenylephrine et al.
Therefore, combination drugs simultaneously eliminate cold symptoms such as:
- Fever;
- Headache;
- Chills;
- Pain in joints and muscles;
- Pain in the sinuses;
- Nasal congestion;
- A sore throat.
It should be remembered that for colds and flu it is undesirable to combine antiviral agents and combination drugs. First, take antiviral drugs, then start treatment with combination drugs.
During a cold, try to rest more. Drink as much warm liquid as possible: tea, compote, fruit juice. Eat easily digestible foods. Take medications strictly as prescribed by your doctor, do not self-medicate. When you have a cold, the most important thing is not to get complications from the disease, remember this and take care of yourself!
03.09.2016 11014
People of all ages suffer from ENT diseases. Doctors note an increase in the number of such ailments in spring and autumn, which sometimes even creates an epidemic situation. This course of events is associated with seasonal temperature changes, violation of personal hygiene rules and weakened immunity. Among the variety of colds and inflammation of the mucous membranes of the upper respiratory tract in general, Theraflu for children and adults takes its rightful place as a symptomatic remedy. And although the treatment of ARVI is not complete without antimicrobial medications, it is Theraflu that provides a decrease in temperature and an improvement in the patient’s condition.
What to take for a cold without fever. List of drugs
When choosing a medicine, it is important to understand the process of treating a cold, in which your body temperature is not raised to unacceptable levels. That is, you can immediately exclude the main drugs that focus on bringing down the temperature, since the active substance present in their composition will still perform its function and, of course, although it will not reduce your temperature to 34, 33 degrees and below, but may have a negative impact on the healing process itself or even slow it down, which is undesirable.
Most of the inexpensive and most effective medicines against colds (TeraFlu, Coldrex, Fervex) contain paracetamol, which primarily fights the patient’s fever; therefore, in our case there is no need to use it, but it is better to choose drugs that contain it minimal. The list of inexpensive medications that are recommended for treatment of colds without fever includes:
- Imunoflazid, - Amiksin, - Lavomak, - Arbidol (capsules), - Tamiflu, - Rinofluimucil (rinsing the nose is the first need for a cold without fever) - Anvi Max, - Ambrobene (removal of sputum for dry cough), - Lazolvan (removal of sputum for dry cough), - Stoptussin (removal of sputum for dry cough), - Kagocel (tablets),
Composition and effect of the drug
A rare medicine replaces several drugs at once. Laboratory research in the 20th century made it possible to combine synthetic substances into one medicine for a combined effect on the body. A similar effect was achieved thanks to the inclusion of three active components in the Teraflu powder:
- Paracetamol.
- Pheniramine maleate.
- Phenylephrine hydrochloride.
Paracetamol for fever is prescribed in case of severe fever. The compound affects the nerve centers responsible for pain and thermoregulation, and in the peripheral parts of cells, peroxidase neutralizes the drug and neutralizes the anti-inflammatory effect. Therefore, pharmacists include additional components for widespread use.
Pheniramine maleate, an H1 receptor blocker, stops the allergic reaction in the form of itching and burning and facilitates the removal of mucous discharge from the nose. Although 20% of the substance entering the body is neutralized by the liver, 80% reaches the source of irritation without metabolic transformations.
Phenylephrine hydrochloride, an α-adrenergic receptor blocker, relieves swelling and increased blood flow to the site of infection due to the narrowing of capillaries at the site of inflammation. The compound is poorly absorbed in the digestive tract and is subject to changes under the influence of monoamine oxidase, which is why the medication is not used in conjunction with MAO inhibitors.
Depending on the release form. In addition to the traditional powder, there are cough tablets intended for resorption in the pharmacy. The active substances in them are benzoxonium chloride and lidocaine hydrochloride, which, through a complex action, relieve pain and neutralize pathogenic microorganisms. Theraflu spray contains the same compounds, but it is used by spraying.
Dosage
The dosage of paracetamol depends on the age of the patient. Separately from the powder, the compound is used from the age of four, but as part of Theraflu - only from the age of 12. Pharmacists attribute this to additional components that negatively affect the child’s body.
Paracetamol at fever is taken 3 times a day with an interval of 4 hours between doses. This time is enough to partially remove the medication and relieve the burden on the liver and kidneys. Take Theraflu for up to 1 week, but if the symptoms do not subside after three days, then self-treatment should be stopped. Seeing a doctor will be the right decision in this situation, because such signs often indicate a serious infection.
Paracetamol for colds will have an effect on the body 15-20 minutes after administration, and the drug will work at full strength after 1 hour. Sometimes the patient becomes sleepy, sometimes the body becomes agitated, but the fever subsides, the eyes become clearer and the person feels an improvement in his condition.
Side effects
Flu medicine is selected individually for each patient. Theraflu and antiviral drugs will relieve respiratory disease. If the symptoms of the disease are acute, then doctors prescribe Theraflu Extra, which contains a double dose of paracetamol. However, the side effects in this case are more pronounced:
- allergies (itching and rash);
- indigestion (stomach pain, nausea);
- nervous disorders (excessive excitement, drowsiness);
- cardiovascular disorders (increased heart rate, increased blood pressure);
- urinary retention;
- increased pressure inside the eyes.
When is a drug prohibited?
The human body reacts to medications differently. One will learn, the other will reject, but medications also affect cells and tissues that were already in a state of pathological disorder at the time of the disease. And doctors take this point into account, naming the following contraindications for Theraflu:
- hypersensitivity to the composition;
- cardiovascular diseases (hypertension, atherosclerosis);
- dysfunction of the thyroid gland (hyperthyroidism);
- acute renal and liver failure;
- glaucoma (angle-closure type);
- taking MAO inhibitors and antidepressants;
- diabetes;
- age up to 12 years;
- alcoholism;
- pregnancy and lactation.
Contraindications for paracetamol include prohibitions for Theraflu, but if this chemical compound is taken separately, doctors allow use by both pregnant women (except the third trimester) and newborns (after 1 month of life). The medicine is available without a prescription, and each patient can independently carry out the course of treatment. However, a medical consultation will not harm, because before prescribing the drug, the otolaryngologist analyzes the clinical picture of the disease and makes a decision depending on many indicators that are not always clear to the patient.
Contraindications
Hypersensitivity to individual components of the drug, simultaneous use of tricyclic antidepressants, monoamine oxidase inhibitors, beta-blockers, portal hypertension, alcoholism, sucrase/isomaltase deficiency, fructose intolerance, glucose-galactose maladsorption, pregnancy, breastfeeding, children under 12 years of age.
With caution:
With arterial hypertension, diabetes mellitus, angle-closure glaucoma, severe diseases of the liver or kidneys, lungs (including bronchial asthma), difficulty urinating with prostate adenoma, blood diseases, congenital hyperbilirubinemia (Gilbert, Dubin-Johnson and Rotor syndromes) ), hyperthyroidism, pheochromocytoma. If you have one of the listed diseases, be sure to consult your doctor before taking the drug.
Pregnancy and breastfeeding
Directions for use and dosage
Inside. The contents of one sachet are dissolved in 1 glass of boiled hot water. Consumed hot. You can add sugar to taste. A repeat dose can be taken every 4 hours (no more than 3 doses in 24 hours). TheraFlu® for colds and flu can be used at any time of the day, but the best effect comes from taking the drug before bed, at night. If there is no relief of symptoms within 3 days after starting to take the drug, you should consult a doctor.
Drug interactions
Theraflu is not allowed to be taken with every drug. The negative effect on the liver increases when interacting with MAO inhibitors and inducers of microsomal enzymes.
Doctors also note a conflict between the drug and ethanol, so chronic alcoholics are recommended to use Theraflu in a smaller dosage.
The use of tetracyclic antidepressants together with this medication increases the risk of digestive and excretory disorders such as constipation and difficulty urinating. The patient should definitely inform the otolaryngologist about taking additional medications, because drawing up the correct course of treatment is the key to speedy healing.
In this article you can read the instructions for use of the drug Theraflu
. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Theraflu in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogues of Theraflu in the presence of existing structural analogues. Use for the treatment of flu and colds in adults, children, as well as during pregnancy and lactation. Composition and interaction of the drug with alcohol.
Teraflu
- a combined drug that has antipyretic, anti-inflammatory, decongestant, analgesic and antiallergic effects, eliminates the symptoms of “colds”.
The effect of the drug is due to the components included in its composition.
Paracetamol has an antipyretic effect by blocking COX mainly in the central nervous system, affecting the centers of pain and thermoregulation. It has virtually no anti-inflammatory effect. Paracetamol does not affect the synthesis of prostaglandins in peripheral tissues, thus not having a negative effect on water-salt metabolism (sodium and water retention) and the gastrointestinal mucosa.
Pheniramine is a histamine H1 receptor blocker. Has an antiallergic effect, reduces exudation.
Phenylephrine is an alpha-adrenergic agonist, constricts blood vessels, eliminates swelling and hyperemia of the mucous membrane of the nasal cavity, nasopharynx and paranasal sinuses, reduces exudative manifestations (runny nose).
Chlorphenamine is an H1-histamine receptor blocker that suppresses the symptoms of allergic rhinitis: sneezing, runny nose, itchy eyes, nose, and throat.
Ascorbic acid increases the body's resistance to infection.
Lidocaine is a local anesthetic that, during inflammatory processes, reduces pain in the throat when swallowing.
Compound
Paracetamol + Pheniramine maleate + Phenylephrine hydrochloride + excipients (Teraflu and Teraflu Extra).
Paracetamol + Chlorphenamine maleate + Phenylephrine hydrochloride + excipients (Theraflu Extratab).
Paracetamol + Pheniramine maleate + Phenylephrine hydrochloride + Ascorbic acid + excipients (Theraflu for flu and colds).
Benzoxonium chloride + Lidocaine hydrochloride + excipients (Theraflu Lar).
Rosemary essential oil + Eucalyptus essential oil + Peruvian balsam + Racemic camphor + excipients (Terfalu Bro).
Guaifenesin + excipients (Theraflu CV).
Vitamin C (ascorbic acid) + Echinacea purpurea extract powder + Hydroxycinnamic acids + Zinc gluconate + excipients (Terfalu Immuno).
Indications
- infectious and inflammatory diseases - influenza, ARVI (“cold”), accompanied by high temperature, chills and fever, headache, runny nose, nasal congestion, sneezing and muscle pain;
- diseases of the respiratory tract with difficult discharge of viscous sputum: pharyngitis, sinusitis, influenza, acute tracheitis, bronchitis of various etiologies, bronchiectasis, bronchial asthma, pulmonary tuberculosis, pneumonia, cystic fibrosis;
- rehabilitation of the bronchial tree in the pre- and postoperative periods;
- tracheobronchitis;
- tracheitis;
- laryngitis;
- catarrhal tonsillitis;
- stomatitis;
- ulcerative gingivitis;
- chronic tonsillitis (as an adjuvant).
Release forms
Powder for preparing a solution for oral administration (wild berry flavor) (Theraflu).
Film-coated tablets (Theraflu Extratab).
Powder for solution for oral administration (lemon flavored) (Theraflu Extra).
Granules for the preparation of a solution for oral administration (Theraflu Immuno).
Powder for preparing a solution for oral administration (lemon and apple cinnamon flavor) (Theraflu For colds and flu).
Lozenges and Spray for topical use (Theraflu Lar).
Ointment for external use (Theraflu Bro).
Drops and syrup (Theraflu KV).
Instructions for use and method of use
Powder
Inside. The contents of the sachet are dissolved in 1 glass of boiled hot water. Consumed hot. You can add sugar to taste. A repeat dose can be taken every 4 hours (no more than 3 doses within 24 hours). TheraFlu can be used at any time of the day, but the best effect comes from taking the drug before bed, at night. If there is no relief of symptoms within 3 days after starting to take the drug, you should consult a doctor.
Extratab tablets
Adults: 1-2 tablets every 4-6 hours, but not more than 6 tablets per day. Children over 12 years old - 1 tablet every 4-6 hours, but not more than 4 tablets per day. It is recommended to swallow the tablet whole, without chewing, with water.
The course of treatment should not exceed 7 days.
If there is no relief of symptoms within 3 days after starting to take the drug, you should consult a doctor.
Lahr tablets and spray
Adults are prescribed 1 lozenge every 2-3 hours or as a spray, 4 sprays (approximately 0.5 ml) 3-6 times a day. For severe symptoms of the disease, it is possible to use 1 tablet every 1-2 hours. The daily dose should not exceed 10 tablets.
Children aged 4 years and older are prescribed 1 lozenge every 2-3 hours or as a spray 2-3 sprays 3-6 times a day. The daily dose should not exceed 6 tablets.
The duration of treatment is no more than 5 days. If there is no relief of symptoms within 5 days of therapy, the patient should consult a doctor.
The tablet should be slowly dissolved in the mouth until completely dissolved. The solution in the form of a spray is sprayed into the oral cavity, holding the can vertically.
Ointment Bro
For adults and children over 3 years old, a small amount of ointment is applied 2-3 times a day to the upper and middle part of the chest and back. Rub lightly until completely absorbed and cover with a dry, warm cloth.
KV drops or syrup
The syrup is prescribed to adults 5-10 ml 4 times a day.
Before use, drops are diluted in water or herbal decoction or dripped onto a piece of sugar.
Children aged 2-3 years are prescribed 8-10 drops 2 times a day; 3-6 years - 12-15 drops 2 times a day; 6-12 years - 15-20 drops 3-4 times a day.
Adults and children over 12 years old - 20-30 drops 3-4 times a day.
Immuno granules
Adults and children over 14 years old: 1-2 sachets per day (the contents of the sachet are poured directly onto the tongue; no need to wash it down with water).
Duration of treatment: 3 weeks.
Side effect
- allergic reactions (skin rash, itching, urticaria, angioedema);
- increased excitability;
- sleep disturbance;
- decreased speed of psychomotor reactions;
- drowsiness;
- dizziness;
- nausea, vomiting;
- stomach pain;
- heartbeat;
- increased blood pressure;
- dry mouth;
- accommodation paresis;
- increased intraocular pressure;
- urinary retention;
- blood picture disorders (anemia, thrombocytopenia, agranulocytosis);
- nephrotoxicity.
Contraindications
- simultaneous use of tricyclic antidepressants, monoamine oxidase inhibitors (MAO), beta-blockers;
- portal hypertension;
- alcoholism;
- diabetes;
- pregnancy and breastfeeding;
- children up to 12 years of age (up to 4 years - tablets and spray Lar) (up to 3 years - Bro ointment) (up to 2 years - KV drops);
- hypersensitivity to individual components of the drug.
Use during pregnancy and breastfeeding
Contraindicated during pregnancy and lactation.
Use in children
Contraindicated in children under 12 years of age (up to 4 years of age - tablets and spray Lar) (up to 3 years of age - Bro ointment) (up to 2 years of age - KV drops).
special instructions
To avoid toxic liver damage, the drug should not be combined with the use of alcoholic beverages.
Impact on the ability to drive vehicles and operate machinery
Drug interactions
Enhances the effects of MAO inhibitors, sedatives, ethanol (alcohol). The risk of hepatotoxicity from paracetamol increases with concomitant use of barbiturates, phenytoin, carbamazepine, rifampicin, zidovudine and other inducers of microsomal liver enzymes.
Antidepressants, antiparkinsonian drugs, antipsychotic drugs, phenothiazine derivatives - increase the risk of developing urinary retention, dry mouth, and constipation. Glucocorticosteroids increase the risk of developing increased intraocular pressure.
Paracetamol reduces the effectiveness of uricosuric drugs and increases the effectiveness of indirect anticoagulants.
Tricyclic antidepressants enhance their sympathomimetic effect; simultaneous administration of halothane increases the risk of developing ventricular arrhythmia. WITH
Reduces the hypotensive effect of guanethidine, which, in turn, enhances the alpha-adrenergic stimulating activity of phenylephrine.
Analogues of the drug Teraflu
Structural analogues of the active substance:
- TheraFlu for flu and colds Extra;
- TheraFlu Extra;
- Flucomp.
If there are no analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps, and look at the available analogues for the therapeutic effect.
For colds and flu in particular, the patient is advised to take bed rest, as well as moisturize the nose so that dry mucous membranes do not allow the virus to sink lower and lead to the development of complications. ARVI can be quite mild, but lead to serious complications. In addition to these measures, symptomatic remedies can also be used at this stage. They usually include
- antipyretics;
- cough suppressants;
- nasal drops.
What are the differences between different antipyretics?
All antipyretics contain one of 4 components: paracetamol, ibuprofen, acetylsalicylic acid or metamizole sodium.
Paracetamol has a pronounced antipyretic and analgesic effect. It gradually and for a sufficiently long time reduces elevated body temperature, and also relieves the patient of headache and muscle pain. At the same time, paracetamol quite rarely causes complications from the digestive, nervous and hematopoietic systems. It should be taken no more than 4 times a day: adults and children over 12 years old - 500 mg or 1 g, children from 3 months to 12 years - in the age dosage specified in the instructions for the drug.
It is important! To reduce fever in children under 12 years of age, only antipyretics based on paracetamol or ibuprofen are used and only in age-appropriate dosage forms.
Ibuprofen begins to act quite quickly and provides a long-lasting antipyretic effect. In addition, it has an analgesic and anti-inflammatory effect, and recently there has been evidence that taking ibuprofen has a positive effect on the functioning of the immune system. Take it no more than once a day: for adults - for children - in an age-specific dosage.
Composition of the drug
The most effective, safe antipyretic drug is paracetamol. This is the remedy recommended by WHO for influenza in children and adults.
Based on it, there are various analogues and combination drugs. One such remedy is Theraflu. It includes
- Paracetamol;
- Phenylephrine hydrochloride;
- Pheniramine maleate;
- Ascorbic acid.
Paracetamol, which is a non-steroidal anti-inflammatory drug, in this combination drug has antipyretic, analgesic, and to a lesser extent, anti-inflammatory effects. Phenylephrine hydrochloride belongs to the group of vasoconstrictors that have a local effect on the nasal mucosa, which helps reduce swelling and reduce nasal discharge. Pheniramine maleate is an antihistamine, the effect of which is also manifested by a decrease in swelling of the mucous membrane, reduction of congestion, itching in the nose, and lacrimation.
The presence of ascorbic acid in the composition of the drug is due to the active participation of the vitamin in the regulation of redox processes, and therefore, the enhancement of immunity.
Since symptoms such as runny nose, nasal congestion, and lacrimation during the flu are mild, and an increase in body temperature is a protective mechanism that ensures more active production of interferons, Theraflu is not often used for the flu.
The drug has become much more widespread in other acute respiratory viral infections, where catarrhal symptoms are more pronounced.
Is it possible to drink Theraflu if there is no fever?
The article is relevant for any time of the year, since you can catch a cold not only in winter and autumn, but also in summer and spring.
Inflammation of the upper respiratory tract (such symptoms are the first signs of a cold) can begin due to extreme weakening of the body and the time of year has nothing to do with it, it’s just usually due to hypothermia or a draft, which is felt much more strongly in cold seasons, but can cause significant hassle both in winter and at the height of summer. A cold is not always accompanied by a fever, and the temperature primarily indicates that the body is strenuously fighting the internal effects on its immune system. Sometimes, even without exceeding normal body temperature, a cold (ARVI) can cause not just serious, but very serious harm to the body.