Tizin for the expectant mother: to breathe freely

Composition and release form

The main active ingredient in Tizin is tetrahydrozoline hydrochloride. It has a vasoconstrictor effect and relieves swelling of the nasopharynx. The drug is available in the form of nasal drops, which may differ in the concentration of the active substance:

1. In the medicine for adults, its share is 0.1%
2. In medicine for children, its share is 0.05%

Excipients are sorbitol solution, hypromellose, 17% benzalkonium chloride solution, benzyl alcohol, sodium citrate, 37% hydrochloric acid, perfume oil, disodium editate, purified water and macrogol glyceryl hydroxystearate.

The drug has a non-proprietary international name "Tetrizolin". The drops are transparent, colorless. There are several varieties: Xylo, Allergy, Xylo Bio, Expert.

The cardboard packaging includes a dark glass bottle with 10 ml drops and instructions for use. The jar is equipped with a special pipette.

Composition and description of the drug

Tizin is produced in two types.

Nasal drops (0.1% and 0.05%) with the active substance tetrizoline. The drops cause a vasoconstrictor effect, which is noticeable within minutes after application and continues for several hours.

Even during pregnancy, Tizin Xylo and Xylo Bio (0.1% and 0.05%) are prescribed - these are sprays with the active component xylometazoline hydrochloride. The active substance of the spray has a constricting effect on the vascular network of the nasal mucosa, which helps relieve swelling.

In what cases is the drug used?

Tizin is used during pregnancy:

• to reduce swelling of the nose and throat;
• to reduce the amount of discharge in case of allergic rhinitis, including pollen;
• with a runny nose accompanying acute colds and viral diseases;
• with symptoms of inflammation of the paranasal sinuses;
• during inflammatory processes in the middle ear;
• when preparing the patient for diagnostic and therapeutic measures.

It is worth noting that almost all internal organs suffer from blocked nasal passages, which do not fully perform their functions. Lack of oxygen also negatively affects the baby, causing a state of hypoxia. Therefore, you should not ignore a runny nose of any etiology during the period of bearing a child.

Advice: Pharmacologists have developed a large number of drugs for the treatment of rhinitis that are approved while expecting a child. These are homeopathic preparations, drops and sprays consisting of sea water. Therefore, Tizin is used during pregnancy only if approved drugs are ineffective.

Indications for use

Tizin is prescribed for rhinitis, sinusitis, pharyngitis and hay fever to reduce swelling of the mucous membrane. It is also used for therapeutic purposes when making a diagnosis.

Possible contraindications

Like many medications, vasoconstrictor nasal drops have a number of contraindications. Tizin should not be used during pregnancy. It should also be avoided if:

1. Angle-closure glaucoma
2. Dry rhinitis
3. Sensitivity to component composition

Drops intended for adults should not be instilled into children under 6 years of age. The children's form of the medicine begins to be given no earlier than 2 years of age.

Caution should be exercised in cases of hypertension, aneurysm, arrhythmia, pheochromocytoma, diabetes, hyperthyroidism and certain diseases of the cardiovascular system. You will have to give up nasal drops if metabolic processes are disrupted.

Contraindications and side effects

The use of drops should be limited if a patient is diagnosed with glaucoma, severe problems in the cardiovascular system, or diabetes mellitus.

The use of drops may be accompanied by a burning sensation, swelling of the nasopharynx, tremors, weakness, a sharp increase in pressure, and migraines.

Uncontrolled use of Tizin can provoke the development of drug-induced or dry rhinitis.

The spray is prohibited while taking medications that increase blood pressure, an increase in the frequency of contractions of the heart muscle, atherosclerosis, diabetes mellitus and a number of other diseases.

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Adverse reactions include a feeling of dryness and burning, sneezing, excessive mucus secretion, less often - migraines, problems with sleep and vision.

It is also necessary to limit the use of Tizin during breastfeeding, since it is not known whether its components are excreted in milk.

Important: dry rhinitis is a disorder of the nasal mucosa, leading to the formation of crusts. This irreversible process occurs with excessive uncontrolled use of Tizin and other similar drugs.

In case of an overdose of drugs, nausea, vomiting, cardiac dysfunction, swelling, convulsions, drowsiness, heaviness of breathing, and coma are observed. If such a situation arises, call an ambulance, wash the stomach and take absorbent drugs.

If we analyze the reviews about taking Tizin during pregnancy, the occurrence of side effects and problems with bearing a child are infrequent, provided that all the doctor’s instructions are followed.

The principle of action of the drug

The pharmacological effect of nasal drops is due to its chemical structure. The main active substance in the group of alpha-adrenergic stimulants, providing a persistent and rapid vasoconstrictor effect.

Instillation of the drug quickly clears the nasal cavities to facilitate breathing.

When applied topically, the active substance of the drops is practically not absorbed. Tizin has an anti-edematous and vasoconstrictor effect.

Drops entering the nose cause constriction of the arterioles and reduce the secretion of nasal secretions.

Composition of Tizin

Tizin is not just vasoconstrictor drops and sprays, united by a common composition and mechanism of action. Depending on what goals are pursued in the treatment of a particular runny nose, the drug is selected according to the active and auxiliary components.

Tizin drops

The release form in the form of drops includes a 0.1% solution of tetrizoline hydrochloride and a set of additional substances. The children's version consists of the same components, but in a lower dosage of the main substance - 0.05%. Bottle volume – 10 ml.

Spray Tizin Xylo

The effect of this spray is due to the content of xylometazoline hydrochloride. The percentage is identical to drops: 0.1% solution for adults and 0.05% for children.

It is believed that the use of drops in pediatric dosage is one of the safest ways to use Tizin. But you shouldn't believe this. The introduction of any volume of the drug with some probability can lead to undesirable consequences.

The composition and quantitative content of the main active ingredient is similar to the previous representative. A distinctive feature is that hyaluronic acid is added to Tizin Xylo Bio. It’s not for nothing that the manufacturers decided to include it in the drug: this component protects the mucous membrane from drying out, softens it and, therefore, promotes speedy healing.

Spray Tizin Alergy

Effectively used for runny nose caused by allergies. This is explained by its composition: Tizin Alergy contains levocabastine hydrochloride (540 mcg per 1 ml).

How to use Tizin drops?

Drops are used intranasally. If your doctor has not prescribed an individual dosage for you, then follow the manufacturer’s dosage:

• 0.1% drops are dripped 2-4 into each nostril. Indicated for adults and children over 6 years of age.
• 0.05% drops are dripped 2-3 into each nasal passage. Used in children aged 2 to 6 years.

It is not recommended to use Tizin more than once every 4 hours. The recommended course duration is no more than 5 days. Like many vasoconstrictor drugs, Tizin is addictive. If its use does not provide improvement, then the drops should be replaced with another medicine.

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Spray or drops?

The drug Tizin belongs to the group of vasoconstrictors that effectively relieve swelling of the nasal mucosa by narrowing blood vessels. It is believed that the use of such drugs during pregnancy is prohibited or allowed in some cases with extreme caution under strict medical supervision. They can be prescribed to a pregnant woman only if there are no contraindications and the expected benefit to the mother outweighs the risk to the fetus.

Tizin is effective for relieving swelling of the nasal mucosa of any origin - infectious diseases, allergic rhinitis. Doctors are of the opinion that it is better to avoid taking the medicine in the 1st and 3rd trimesters, since during these periods the risk of complications increases. In the 2nd trimester, Tizin is used with caution strictly according to indications.

The Tizin line of drugs is available in different forms and has different characteristics. Contact a specialist you trust, he will determine which drug from this line to choose and what dosage (for adults - 0.1% or for children - 0.05%) is best to use.

The Tizin trademark combines a whole line of drugs for the treatment of rhinitis, differing in composition, dosage and release form. To determine which medicine is more effective, you should consider each representative in detail.

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It is believed that using a spray is the safest. When using Tizin in the form of drops, problems may arise with dosing, flow of the drug into the nasopharynx and its subsequent ingestion (which is extremely undesirable). Currently, the release of Tizin in this form has been discontinued.

Using the spray is convenient and safe: the required amount of the drug corresponds to the number of presses on the dispenser.

Side effects

Tizin may have side effects with long-term use (more than 5 days). it can manifest itself in:

1. Tingling
2. Burning
3. Dry nasal cavity
4. Recurrent rhinitis

Headaches, tremors in the limbs, weakness in the body, increased sweating, increased blood pressure and increased heart rate are much less common. If you are intolerant to the components of the composition, an allergic reaction may occur.

Indications

Drugs with a vasoconstrictor effect can seriously disrupt the functioning of a pregnant woman’s body. They have a number of restrictions when used, in particular, they cannot:

• use if you are intolerant to any of its components;
• combine with taking antidepressants (MAO inhibitors);
• take if there are contraindications.

Tizin Xylo spray is used not only for therapeutic purposes, but also as part of preparatory therapy before diagnostic procedures.

The main list of indications includes:

1. Rhinitis and pharyngitis in acute respiratory diseases. Tizin helps reduce mucus secretion, restoring normal nasal breathing.
2. Otitis media Thanks to the action of the active substance, swelling of the mucous membrane is reduced, the patency of the Eustachian tube is restored and, consequently, the pressure on the eardrum is reduced.
3. Sinusitis (frontal sinusitis, sinusitis) in combination with the main therapy.
4. Preparation for diagnostic and therapeutic procedures. Inflamed, edematous mucosa can interfere with rhinoscopic examination and the introduction of the necessary instruments during puncture of the maxillary sinus. Tizin Xylo causes constriction of the arterioles, thereby restoring air flow in the nose.
5. Hay fever (a disease of an allergic nature associated with seasonal flowering of plants, manifested by severe rhinitis with copious mucous discharge).

Tizin Xylo Alergy has a different mechanism of action from xylometazoline and is used exclusively for rhinitis of an allergic nature.

Despite the fact that the sprays of the Tizin line (Xylo and Xylo Bio) are topical preparations that do not have strong toxicity or other negative effects, they must be treated with caution. Can Tizin be used by all patients? No.

Absolute contraindications:

• Hypersensitivity to active components (for Tizin Alergy this is the only existing obstacle to use).
• Dry rhinitis (inflammation may increase due to additional drying of the nasal mucosa).
• Age under 2 years (any dosage starting from 0.05% is prohibited).
• Age less than 6 years (0.1% sprays are not allowed, but 0.05% are allowed).

The list of relative contraindications to the use of Tizin is much wider. The use of a spray in this case is not prohibited, but requires special attention and consultation with your doctor. A comparison of possible risks and benefits will be needed for many chronic diseases.

Relative contraindications:

1. Various types of cardiovascular pathology (coronary heart disease, including severe arrhythmia, arterial hypertension, vascular and cardiac aneurysm).
2. Benign tumor of the adrenal gland (pheochromocytoma).
3. Metabolic diseases in the stage of sub- and decompensation (diabetes mellitus, hyperthyroidism).
4. Taking medications that increase blood pressure (citramon, some antidepressants and other drugs);

A special FDA system has been developed to assess the degree of risk to the pregnant woman and fetus when using medications. According to this scale, the drugs in the Tizin line belong to category C. This means that proper clinical studies have not been conducted for ethical reasons, and there is no reliable data on a pronounced negative effect on the health of mother and child.

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Therefore, the use of the drug Tizin Xylo during pregnancy is permissible, but only if the benefits of its use significantly outweigh the risk of negative effects.

Breastfeeding is also not an absolute contraindication to the use of Tizin Xylo, Xylo Bio and Allergy. However, strict adherence to the instructions is required.

Before starting to use the medicine, you must carefully study the attached instructions and exclude possible contraindications. It is important to note that for each drug from the Tizin line they are different.

If Tizin is used irrationally or inattentively, a pregnant woman may develop a number of side effects. You should carefully monitor your well-being during treatment and if you notice any unpleasant symptoms, stop using the product and consult a doctor.

Overdose

An overdose may be accompanied by dilated pupils, arrhythmia, tachycardia, and the presence of seizures. Pulmonary edema, respiratory distress, hypertension and mental disturbances may occur.

Cardiac arrest may even occur. To prevent the onset of such consequences, you should rinse your stomach, drink activated charcoal and, if necessary, take an antipyretic or anticonvulsant medication.

Analogs

Analogues in terms of the therapeutic effect they provide are:

• Naphthyzin
• Nazivin
• Xylene
• Tizin Xylo
• Tizin Xylo Bio
• Tizin Allergy
• Pinosol
• Snoop
• Nazol
• Koldak
• Bioparox
• Arthromax

You can purchase any of the most suitable decongestant and vasoconstrictor drops. The cheapest analogue is “Xylene” drops - from 25 rubles.

Tizin's analogs

About the effect of the drug "Tizin" during pregnancy

Following the instructions for using Tizin during pregnancy, the use of the drug is not prohibited. The medication does not have components that can penetrate the blood and cause fetal development disorders. But keep in mind that there are no proven facts about the absence of harm to the embryo. Therefore, do not use Tizin for children during pregnancy without a doctor’s prescription.

In case of an incorrect diagnosis, it is possible that a systemic reaction will develop, which will lead to pathological changes that can harm the baby.

A systemic effect can also occur if the dosage is incorrectly selected.

In this case, the baby’s oxygen supply may be reduced, which can lead to death.

It is for this reason that it is important to seek help from a trusted doctor and undergo a full examination.

Therefore, treatment of inflammation during pregnancy must begin at the very initial stages. When answering the question whether Tizin can be taken during pregnancy, it is necessary to clarify all the side effects of the drug, but there are no direct contraindications.

It is important to note that treatment with Tizin during pregnancy in the 1st trimester is undesirable, since the vasoconstrictor drug can cause a pathological structure of the placenta, which will negatively affect the child.

You can use Tizin spray without fear in the 2nd trimester, since at this time the placenta is fully formed. There is no need to be afraid that the drug may disrupt the development of the child, since he is under good protection.

Treatment in the 3rd trimester should be under the full supervision of a doctor, since any vasoconstrictor drug can be dangerous for the expectant mother. In case of a side effect in the form of increased blood pressure, there is a risk of premature birth.

In every case of pregnancy, you should consult your doctor. There are cases when during one pregnancy the drug does not cause any side effects, when in another situation it can provoke the worst effects.

When can Tizin be prescribed?

"Tizin" is intended to restore the functions of the respiratory tract, which makes it easier to breathe through the nose, as well as reduce nasal congestion.

After diagnosing the pregnant woman’s condition, patients may be prescribed a spray
for the following ailments:

• allergic rhinitis;
• acute inflammation of the respiratory tract;
• nasal congestion caused by an allergen;
• acute respiratory illnesses;
• copious mucous discharge due to frostbite;
• sinusitis;
• sinusitis;
• hay fever;
• inflammation of the middle part of the ear.

Do not forget that the treatment of acute inflammation requires an integrated approach. Therefore, Tizin is most often prescribed only as an additional remedy in the treatment of ailments. Immediately after using the medicine, the patient’s respiratory tract functions normalize.

This effect of the drug is due to its composition. The active component of the drug is xylometazoline . It is included in Tizin Xylo, Tizin Xylo Bio and Tizin Alergy. The effect of the substance lasts for eight hours. During this period of time, there is a narrowing of blood vessels, as well as an active effect on the receptors of the mucous membrane of the sinuses, reducing swelling and improving blood circulation.

Pregnant women should not be afraid of negative effects on the body, since xylometazoline is not prohibited in the case of fetal development.

It has only a local effect and is not absorbed into the blood vessels.

Thus, penetration into the plasma does not occur . This indicates that there is no risk to the development of the embryo.

Note that the effect of “Tizin” is not the highest. In the case of the patient’s normal position, this fact will not be a plus. But during pregnancy, the short action of the medication allows you to use the medication for up to ten days without fear. During the course of treatment you should not expect the development of side effects and systemic reactions.

Side effects

In case of pregnancy, only the attending physician can prescribe the drug .
Keep this in mind when choosing your own medication. You may make a mistake or unknowingly choose another type of Tizin, which is contraindicated during pregnancy. So, in case of fetal development, it is prohibited to use such types of spray as “Tizin Xylo” and “Tizin Xylo Bio”.

These medications contain active ingredients that increase blood pressure. In the case of pregnancy, such a side factor can lead to miscarriage in the early stages of pregnancy. And when treated with such drugs in the third trimester, early birth is possible.

Therefore, when expecting a baby, it is best to be treated with a pediatric type of drug. Children's "Tizin" does not cause unwanted reactions and has virtually no contraindications.

Remember that each release of the drug "Tizin" has its own characteristics.

The most common side effects that may occur during pregnancy are:

• severe nausea;
• headache;
• fatigue;
• drowsiness;
• severe dizziness;
• dysfunction of the vestibular apparatus;
• painful sensations in the nasopharynx;
• pain when eating or drinking;
• feeling of dryness;
• formation of burning and itching;
• serious discomfort;
• deterioration of health.

In rare cases, nosebleeds and severe swelling in the nasal mucosa may occur, as well as coughing and shortness of breath.

In extremely rare cases, changes in heartbeat, increased blood pressure, various allergic reactions, and impaired visual acuity occur.

Contraindications

As your baby develops, you need to be sure there are no contraindications.
Therefore, before using any medicine, pay attention to the instructions.

The instructions for Tizin indicate that treatment with this medication is prohibited in the following cases::

• do not use the drug if you are particularly sensitive to the components of the drug;
• It is prohibited to use Tizin while taking MAO inhibitors;
• persistent increase in blood pressure;
• glaucoma;
• atrophic runny nose;
• hyperfunction of the thyroid gland;
• serious inflammation of the heart;
• change in heartbeat;
• arterial hypertension;
• acute atherosclerosis;
• surgical operations on the brain area;
• diabetes;
• metabolic disease;
• kidney or liver dysfunction.

Do not use the medicine for the listed ailments.