Bronchodilator drugs list for bronchitis

From the article you will learn what bronchodilators are, when they are used in medical practice, for whom they are contraindicated, what side effects can be expected after taking the drugs.

Bronchodilators are symptomatic medications that relieve bronchospasm by affecting smooth muscles and the structures that regulate their function.

Manufacturers of bronchitis products

To treat bronchial pathologies, you should take a comprehensive approach to the choice of drugs. Moreover, many analogue drugs are produced by several companies at once. It is difficult for the average buyer to choose, so experts suggest starting to get acquainted with trusted manufacturers. The best remedies for bronchitis were suggested by the following:

• OJSC Pharmstandard-Leksredstva (Bromhexine) is one of the largest pharmaceutical companies in Russia, one of the top 5. It is an active participant in the import substitution program, creating worthy analogues to imported drugs. About 500 million packages are produced annually.
• "PRO.MED.CS Praha as" (Ambrosan) is a leading independent pharmaceutical company in the Czech Republic with its own research base. Thanks to this, she manages to create high-quality generics and her own patented medicines. The company produces 1.5 million tablets daily only. Most of them are intended for the musculoskeletal, digestive, and cardiovascular systems.
• Pharma Wernigerode Gmbh (Eucabal) is a pharmaceutical company from Germany, founded in 1903. Most of the drugs produced are presented in liquid forms - extracts, ointments, creams, gels, etc. Among them, a large share is based exclusively on natural ingredients.
• Vertex (Carbocisteine) is a well-known Russian pharmaceutical company specializing in dietary supplements and preventive medicines. The main ingredient for their creation is a medicinal herb. It takes pride of place among the fast-growing drug manufacturers in Russia.
• Europlant Fitofarm (Breast collection No. 4) is a trademark that is part of the group. She is recognized as an expert in the production and sales of herbal medicines. The herbal products produced cover most areas of medicine, offering alternative treatment.
• Krka, dd (Theotard) is an international pharmaceutical company that began its activities in 1954 in Slovenia. Engaged in the production of high-quality generics. Since 2007, it has been actively expanding its market share in Western Europe. Each product unit meets international quality standards.
• CJSC Altaivitamins (Salbutamol) is a team of professionals with many years of experience in the pharmaceutical field. It originates from the city of Biysk, where the company was founded in 1949. Then it was a vitamin and confectionery factory, and today it is a large pharmaceutical complex.
• Boehringer Ingelheim (Berodual) is a family-owned pharmaceutical company founded in Italy in 1885. Today it is one of the top 20 global drug manufacturers. There are 142 representative offices in different countries. The brand has become famous for its wide range of drugs, including those for treating animals.
• Nativa LLC (Fenoterol-Nativa) is a full-cycle pharmaceutical company with a European level of management. The manufactured products comply with GOST requirements. Specializes in the production of drugs for the treatment of socially significant diseases. Founded in 2010.
• FP "Obolenskoe" (Azithromycin) is a pharmaceutical production focused on the production of socially significant drugs. Great emphasis is placed on antiviral, antibacterial, and antiallergic agents. All products comply with international requirements and GMP and ISO standards.
• Pharmstandard (Azitrox) is one of the largest pharmaceutical companies in terms of production and sales in Russia. Founded in 2003. Every year, over 1.7 billion packages of medicines for all areas of medicine are produced under this brand. There are 9 large factories scattered across the country. Participant in the import substitution program.
• Biochemie GmbH, Sandoz (Ospamox) - the Austrian company Sandoz is the owner of many large pharmaceutical enterprises, and since 1963, Biochemie GmbH. It itself is part of the Novartis group, being a leading developer of high-quality generics and biosimilars.
• OJSC "Tathimfarmpreparaty" (Erythromycin) is a Russian enterprise that produces medicines at a leading speed and volume. In this regard, it is among the top 20 countries in terms of scale of activity. Founded in 1931. Today there are two plants - a chemical and pharmaceutical plant, as well as a plant for the production of suture and surgical materials.
• CJSC "FIRN M" (Grippferon) is a biotechnology company that was founded during the Soviet Union in 1989. Today it demonstrates stable development dynamics and occupies a leading position in the production of ophthalmic drugs. Thanks to the creation of a research center, new medicines are being developed.
• APF-Trading LLC (Kipferon) is a trading company in the domestic pharmaceutical market, operating for more than 15 years. Performs wholesale sales of medicines to national distributors independently or through transport companies. It is directly related to most exclusive medicines.

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Rating of remedies for bronchitis

The doctor must select an effective remedy for bronchitis based on the examination. Such medications are presented in pharmacies in a huge variety, which makes it difficult for the buyer to choose. The VyborExpert project team compiled a list of defining criteria by which the selection of nominees for the rating was carried out. It included:

• Active component – ​​natural, synthetic, combined composition;
• Release form – tablet form, liquid solutions, local agents;
• Application – initial, acute, chronic bronchitis;
• Age group – the possibility of using the medicine at different ages;
• Principle of action – expectorant, antiviral, antibacterial effect;
• Application regimen - course, dosage, frequency of administration, other nuances;
• Limitations – contraindications, risks of developing unwanted reactions of the body;
• Tolerance – degree of bioavailability, sensitivity of the body to the composition;
• Compatibility – interaction with other medications, restrictions;
• Special instructions - is it allowed to take during pregnancy, lactation, etc.

Experts conducted research, collecting the opinions of various pediatricians and therapists, their experience in treating such a disease, in order to select the most purchased medications. Next, we assessed them for the ratio of price to quality. Feedback from patients suggested the advantages and disadvantages of each nominee in the review.

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What are bronchodilators?

The respiratory system ensures human life. When it is affected by viruses and infections, the quality of life deteriorates, and other organs and systems also suffer.

In order to normalize the functioning of the bronchi and eliminate the infection, the doctor prescribes bronchodilators, which are selected taking into account the causative agent of the disease and the severity of the lesion.

The clinical pharmacology of bronchodilators allows them to be used for:

• Bronchial asthma.
• Bronchitis.
• Pulmonary edema.
• Ciliary dyskinesia.
• COPD

Bronchodilators help relieve spasms, prevent narrowing of the bronchi and relax their muscles. Their use is relevant for the accumulation of mucus and swelling.

Some bronchodilators are used to treat persistent cough.

The best antiviral drugs for bronchitis

Since the most common cause of this disease is the penetration of a virus, doctors actively use antiviral medications for the comprehensive treatment of patients. They demonstrate the best results against acute bronchitis, since it is advisable to take them in the first days of the onset of alarming symptoms. The highest percentage of favorable reviews was shown by 2 drugs included in the expert rating.

Grippferon

An effective and safe antiviral drug in the form of spray and drops. They are intended for the treatment of acute respiratory infections, acute respiratory viral infections, and seasonal influenza. The main difference from its analogues is its acceptability from the first days of life, during pregnancy and lactation. The main substance in the composition is highly active recombinant interferon alpha-2b, it does not allow the reproduction of any viruses. Feeling better is observed already on day 2. In this case, the effect of addiction to the action is completely eliminated. Grippferon is also used as a prophylaxis for seasonal colds. Treatment is allowed in conjunction with vaccination.

Advantages

• Blocks all human respiratory viruses;
• Non-toxic, safe;
• Inability to develop viral resistance to the composition;
• No addiction;
• Pronounced anti-epidemic effect;
• Allowed for pregnant women and children.

Flaws

• Short shelf life;
• Price.

As soon as alarming symptoms occur, the spray or drops should be instilled into the nose for 5 days several times a day. After this, it is advisable to massage your nose to evenly distribute the solution. There are no contraindications, except intolerance due to tactlessness.

Kipferon

Immunomodulator in the form of suppositories for rectal administration. It contains interferon, which is combined with human immunoglobulin (G, A, M), and therefore has an anti-inflammatory, antitumor, antibacterial, and antiprotozoal effect. The list of indications includes ARVI, tracheitis, laryngotracheitis, diseases of the oropharynx, intestinal dysbiosis, genitourinary infections, etc. The age limit is from 1 year. Kipferon is common in medical practice as a prophylactic agent. It is allowed for pregnant women only in the 3rd trimester.

Advantages

• Human recombinant interferon;
• Wide range of applications;
• Persistent antibacterial properties;
• Increased immune strength;
• Non-toxic, safe;
• Children allowed.

Flaws

• Price;
• Risks of overdose.

Suppositories can be administered rectally or vaginally; one package is enough. There are no strict contraindications to Kipferon; the main condition for safe and effective treatment is compliance with the dosage, regimen, and course duration. Negative reactions are possible, reviews of the remedy for bronchitis specify that these are allergies, cold symptoms, burning and itching, exacerbation of chronic viruses.

Pharmacological groups of drugs that dilate the bronchi

In modern pharmaceuticals, there are three main groups of drugs that have been introduced into clinical practice since the 70s of the last century.

Anticholinergic bronchodilators

This group of drugs appeared first among the drugs affecting the condition of the bronchi. Their main effect is blocking cholinergic receptors, biochemical, active cell structures that convert energy into a nerve impulse or muscle contraction .
According to their mechanism of influence, they are divided into 3 subgroups.

M-anticholinergic blockers are drugs that stop the activity of special receptors that are located in cell membranes and soft tissues of internal organs along the cholinergic fibers. The drugs reduce or eliminate the influence of the parasympathetic nervous system on body systems. Under their influence, the secretion of bronchial exudate decreases.

List of bronchodilators:

• Atropine is used orally in tablet form and parenterally. There are no age restrictions.
• Platiphylline is prescribed orally and subcutaneously. The medicine has a wide list of contraindications, so it is prescribed to patients over 15 years of age.
• Scopolamine - used orally or subcutaneously. It has a pronounced sedative effect and causes drowsiness. Side effects: delirium, hallucinations. Prescribed to adult patients over 18 years of age.
• Metacin is available in tablets for oral administration and solution for intravenous administration. In children, the drug can thicken mucus and form plugs in the bronchi, so it is prescribed mainly to adults.
• Ipratropium bromide is a product that is used only for inhalation and is produced in the form of an aerosol, solution and powder. The drug is used in pediatric practice.

Ganglioblockers are active substances that block H-cholinergic receptors in ganglia, the nerve nodes of the autonomic system.
They limit the influence of the central nervous system on the activity of internal organs, suspend reflexes at the local level, the center of which is concentrated in the ganglia. List of ganglion blockers with bronchodilator effect:

• Hexamethonium - the drug is administered subcutaneously, intramuscularly, intravenously. In pediatrics, it is used in case of urgent care for severe bronchospasm.
• Dimecoline iodite – coated tablets for use in adults. A side effect is orthostatic collapse.
• Pempidine is a powder for oral administration, intended for adults.
• Pachycarpine - tablets and solution for subcutaneous and intramuscular administration. The product is highly toxic and can cause severe poisoning of the body.

Muscle relaxants - block H-cholinergic receptors of striated muscle groups, which leads to their relaxation . The transmission of nerve impulses is blocked, the conduction of impulses from nerves to muscle tissue is disrupted.

List of medicines:

• Mellictin – tablets for oral administration.
• Vecuronium bromide is intended for intravenous administration in severe cases of the disease.
• Dioxonium is a solution for injection into a vein. The drug is used only in intensive care conditions simultaneously with artificial ventilation of the lungs.
• Tubocurarine is administered intravenously. If administered carelessly, it may cause respiratory arrest. It is a long-acting bronchodilator.

Methylxanthines

These are neurostimulants. Such bronchodilators are prescribed for bronchial asthma and in the last stages of obstructive pulmonary disease .
Depending on the duration of exposure, they are short-acting and long-acting. They relax the muscular layer of bronchi of various calibers and relieve spasms. Drugs in this group are prescribed to infants from birth to prevent respiratory arrest. Names of medicines:

• Aminophylline;
• Teopek;
• Diaphylline;
• Theophylline;
• Theotard;

β2-agonist drugs

Chemicals stimulate receptors that are located in the cells of the bronchial mucosa and produce sputum. Participate in the mechanism of smooth muscle relaxation. Bronchodilators of this group are used to eliminate attacks of spasm and suffocation .
Medicines from the β2-agonist group:

• Salbutamol;
• Fenoterol;
• Formoterol;
• Terbutaline;
• Ephedrine.

Combined bronchodilators

Combined bronchodilators have been developed for the treatment of chronic processes in the lower respiratory tract. They are prescribed in the form of inhalations and have a long-lasting effect .
The use of drugs from different groups increases the effectiveness of treatment. Combination drugs:

• Berodual (ipratropium + fenoterol);
• Seretide (fluticasone + salmeterol);
• Tevacomb (fluticasone + salmeterol);
• Symbicort (formoterol + budesonide);
• Foster (formoterol + beclomethasone);
• Zenhale (formoterol + mometasone).

What is the best remedy for bronchitis?

Any colds, viral or infectious diseases of the respiratory system require examination and complex therapy through different groups of medications. What to choose at the pharmacy, what to buy, what to treat, the doctor and the recommendations of experts from the magazine VyborExpert will tell you. A comparative analysis of the presented medications for bronchitis showed:

• Ambrosan is a highly effective inexpensive expectorant;
• Eucabal is a safe herbal formula that can be combined with various medications;
• Chest collection No. 4 - a folk collection of herbs with a general tonic systemic effect;
• Salbutamol - first aid for suffocation, coughing attacks and obstruction;
• Erythromycin is a universal, gentle antibiotic for all age groups;
• Kipferon is a human recombinant interferon for stimulating the immune system.

As soon as alarming symptoms arise, it is important to take measures to ease breathing, speed up the removal of mucus, and destroy the pathogen. Before selecting home control methods, consult a medical specialist and read the instructions from the manufacturer in detail. You need to know in advance whether there is an allergy to the ingredients, so as not to provoke unwanted reactions in the body.