Complex drops for nasal swelling

Mezaton is a vasoconstrictor with a wide spectrum of action. The medicine in the form of drops is used to lower the pressure inside the eyeball and enlarge the pupil. Mezaton eye drops should be used only after consultation with a doctor and under his direct supervision.

Used in the form of ampoules, the drug increases heart contractions and increases blood pressure, slows down peristalsis and dilates the bronchi. Instructions for using Mezaton in ampoules suggest various ways of introducing the drug into the patient’s body.

Release form, composition and packaging

Eye drops are colorless, transparent.

Excipients: benzalkonium chloride (preservative), potassium hydrogen phosphate, potassium dihydrogen phosphate, sodium chloride, water for injection.

5 ml - polymer dropper bottle (1) - cardboard packs.

The eye ointment is translucent, white with a yellowish tint.

Excipients: white petroleum jelly, liquid paraffin, lanolin.

2.5 g - aluminum tubes (1) - cardboard packs.

pharmachologic effect

Combined preparation for local use in ophthalmology. The drug ensures a sufficient dose and compatibility of both active components, and also reduces the likelihood of errors in dose selection in the case of separate administration of the components included in the drug.

Gentamicin is a water-soluble antibiotic of the aminoglycoside group. It has a bactericidal effect against a wide range of gram-positive and gram-negative bacteria. Gentamicin does not penetrate the intact cornea. Damage and inflammation of the cornea lead to the penetration of gentamicin through the cornea into the anterior chamber of the eye 15 minutes after instillation of eye drops or application of eye ointment.

Dexamethasone is a synthetic corticosteroid, the anti-inflammatory and antiallergic effect of which is 25 times greater than the effect of cortisol, which is a natural endogenous corticosteroid. Dexamethasone may penetrate through the cornea with intact epithelium into the aqueous humor of the anterior chamber of the eye; however, in the case of an inflammatory process or damage to the epithelium, the rate of penetration of dexamethasone through the cornea significantly increases.

Complex nasal drops for a child and features of their use

If a child has a runny nose that lasts for more than 10 days, purulent discharge, or symptoms of sinusitis or sinusitis appear, the ENT doctor may prescribe complex nasal drops. Complex drops are a more effective method of treatment than using all the products separately - the composition of the drops is selected individually, and all the necessary substances enter the body at the same time.

Advantages

Complex nasal drops are selected by the doctor individually for each child, taking into account his age, health condition and complaints. The advantage of manufactured drops is that they:

• are much cheaper;
• freshly prepared;
• are made strictly according to a doctor’s prescription, which means they are optimally selected for your child, taking into account the severity of the disease, the shape and type of the runny nose, and sensitivity to antibiotics.
• provide the opportunity to select the best combination of components for allergies to certain medications.
• are a worthy remedy for the treatment of sinusitis.

Not every pharmacy prepares drops, but only the so-called production ones, the number of which is small in the city. You can find such pharmacies at children's hospitals and clinics.

You can buy ready-made complex combination drugs on sale, for example, Polydexa, Vibrocil and Nasonex.

Indications

Complex nasal drops are prescribed:

• For a runny nose that cannot be treated with other medications within 10 days;
• For allergies;
• Nasopharyngitis;
• For the treatment of sinusitis, including allergic sinusitis;
• Bordizone is intended for the treatment of adenoids. Bordizone is also prepared in a pharmacy with a doctor's prescription.

What do they include

The complex drops contain only pharmacological preparations; they do not have additives, fragrances or dyes.

The composition of the drops depends on several factors, including the form of the runny nose - allergic, viral or bacterial, and the course of the disease - acute, appearing for the first time, or an exacerbation of a chronic disease.

List of main pharmacological groups of drugs that are included in complex drops prescribed for the treatment of children:

1. Decogestants or vasoconstrictors: Metazon, Naphthyzin, Xylometazoline (Pharmazolin, Galazolin), Oxymetazoline (Nazivin).
   They quickly and for several hours relieve swelling of the nasal mucosa, eliminate congestion, and make breathing easier. Treatment with drops containing a vasoconstrictor should not exceed 3–7 days due to the risk of developing atrophy of the nasal mucosa.
2. Antihistamines: Diphenhydramine or Suprastin is usually used.
   Intended for the treatment of sinusitis of allergic origin, runny nose due to allergies and bronchial asthma.
3. Bactericidal agents, including antibiotics.
   For example, Lincomycin, Gentamicin, Cefazolin, Furacilin, Dioxidin, Miramistin. They are prescribed to disinfect the nose, destroy bacteria, and stop their reproduction. Also to prevent the development of a bacterial infection during a prolonged cold, especially if there is a predisposition to the development of sinusitis - a deviated nasal septum, immunodeficiency, polyps or adenoids.
4. Hormonal agent. Most often these are glucocorticosteroids - Hydrocortisone or Dexamethasone.
   Both Hydrocortisone and Dexamethasone have a rapid and persistent anti-inflammatory effect, relieve swelling and allergic reactions. Hormonal drugs should not be used for a long time, not only in children, but also in adults. In childhood, the danger comes from dysfunction of the adrenal glands that produce growth hormone.

   Therefore, some drugs are approved only for children over 6 years of age. Bordizone contains Hydrocortisone.

   Read also:  Hyoxyzone ointment instructions for use in the nose
5. Saline solution or injection water. Included in all drops.

A detailed description of contraindications, side effects and the age at which they can be used is contained in the official instructions for use.

Approximate content

approximate composition of complex drops. We do not indicate concentrations and doses, as this should be done by the attending physician. Making and using these drops yourself may pose a risk to your child's health.

• Recipe No. 1: Farmazolin-Dioxidine-Hydrocortisone.
• Recipe No. 2: Metazon-Dioxidine-Hydrocortisone.
• Recipe No. 3: Naphthyzin-Dexamethasone-Miramistin.
• Recipe No. 4: Galazolin-Dexamethasone-Dioxidine.
• Recipe No. 5: Nazivin-Dexamethasone-Dioxidine.
• Recipe No. 6: Farmazolin-Diphenhydramine-Cefazolin-Hydrocortisone.
• Recipe No. 7: Nazivin-Lincomycin-Dexamethasone.

Sometimes, to treat sinusitis or a runny nose in children, the doctor additionally includes aloe juice, eucalyptus, menthol or pine oil in the composition. This is done provided that the added substances do not cause allergies in the child.

How to use

Before instillation, for better penetration of the medicine into the mucous membrane, the nose should be rinsed well with saline solution and cleared of secretions.

To cleanse the nose of crusts 10–15 minutes before the procedure, it can be treated with any vegetable oil. Then place 2-3 drops of medicine into each nostril.

If the child refuses instillation, you can soak a cotton swab in the medicine and insert it into the nose for a few minutes.

The frequency and duration of use is determined by the doctor individually in each case.

Flaws

• Contraindicated for children under 5 years of age.
• It is difficult to find a commercial pharmacy even in large cities, not to mention small towns and rural areas, where such drops are simply not available to residents.
• This combination medicine has not undergone clinical trials, so its effect on the body of children and the consequences of its use are unknown.
• Not all substances included in the composition are intended for instillation into the nose.
• The more drugs there are, the more contraindications and side effects, and the higher the risk of developing allergies.

If there is no pharmacy that prepares prescription medications, then the drops can be made independently according to the prescription and instructions from the doctor.

However, this option is suitable for older children, since the dosage may be inaccurate and the preparation conditions may be far from sterile.

Storage conditions

The prepared product can be used within 7 days. It should be stored in the refrigerator; before use, take the solution into a pipette and warm it in a warm palm.

If, after using complex drops, children develop undesirable symptoms such as jumps in blood pressure, nosebleeds, arrhythmia, discomfort and dry nose, the drops should be discontinued.

Perhaps the doctor chose the wrong dosage, or your child has an intolerance to one of the components included in the composition.

Source: https://antigaimorit.ru/lekarstva/slozhnye-kapli-rebenku.html

DEXA-GENTAMICIN: DOSAGE

Dex-Gentamicin eye drops are instilled into the conjunctival sac, 1-2 drops 4-6 times a day.

A strip of ointment 1 cm long is placed in the conjunctival sac 2-3 times a day. When applying the ophthalmic ointment, avoid contact of the tube with the surface of the skin or conjunctiva.

The duration of treatment with Dex-Gentamicin usually does not exceed 2-3 weeks. The duration of therapy is determined by the effectiveness of the drug, the severity of symptoms and the likelihood of side effects.

When using several ophthalmic drugs simultaneously, it is recommended to add Dex-Gentamicin in the form of an eye ointment no earlier than 15 minutes after using eye drops.

Indications for use

Used for collapse, arterial hypotension, various intoxications, during preparation and conduct of operations.

Mezaton nasal drops help ease nasal breathing during flu, colds, hay fever and other allergic reactions that are accompanied by acute rhinitis or sinusitis.

Mezaton eye drops are used to dilate pupils during various ophthalmological procedures, as well as for the prevention and treatment of iritis and iridocyclitis.

Contraindications

• keratitis,
• caused by Herpes simplex or Varicella zoster viruses (dendritic keratitis);
• viral diseases of the cornea and conjunctiva (incl.
• with chicken pox);
• mycobacterial eye infections;
• fungal eye diseases;
• acute purulent eye diseases with damage to the corneal epithelium;
• corneal epitheliopathy;
• increased intraocular pressure;
• hypersensitivity to the components of the drug.

It is not recommended to use contact lenses while using the drug.

special instructions

When using the drug for more than 2 weeks, as well as in patients with a history of open- and closed-angle glaucoma, it is recommended to regularly monitor intraocular pressure.

If the use of contact lenses is necessary, they should be removed before using Dexa-Gentamicin in the form of eye drops and reinserted no earlier than 20 minutes later.

The patient should be informed that if side effects occur, treatment should be stopped immediately and contact an ophthalmologist.

Use in pediatrics

To date, there are no data from clinical studies of the safety and effectiveness of the drug Dexa-Gentamicin in children. The use of the drug in pediatrics is possible if the expected therapeutic effect exceeds the potential risk of side effects.

Impact on the ability to drive vehicles and operate machinery

Immediately after using the drug Dex-Gentamicin, a short-term disturbance in visual acuity may occur, leading to a slowdown in psychomotor reactions. Therefore, it is not recommended to use the drug immediately before working with machinery or driving vehicles.

Instructions for use

Each pack of medicine contains an insert with instructions. It contains information about indications, method of administration, drug combinations, side effects, overdose, contraindications, composition. In addition, the instructions also contain reviews.

Indications

The drug is prescribed for the treatment of conditions such as:

• Keratitis, stye, blepharitis, conjunctivitis;
• prevention of inflammatory diseases in the postoperative period.

Method of administration

Attention! Before starting to use Dex-Gentamicin drops, you should consult your doctor.

Treatment should proceed according to the following scheme:

• It is necessary to drop 1-2 drops into each eye once;
• The interval between instillations depends on the patient’s condition, as well as the severity of the inflammatory process. If the condition is severe, drops should be instilled every 4 hours. If the condition is not critical, then instillation should be done every 6 hours;
• Treatment should in no case exceed 20 days, because otherwise, any complications begin to develop. It is also extremely important to follow all doctor’s recommendations during treatment.

• Mycoses of the eyes;
• Viral eye infections;
• Erosion of the corneal epithelium (as a result of taking the drug, these lesions may become deeper);
• Increased intraocular pressure;
• Tuberculosis of the eyes;
• Allergy to certain components of the drug.

In addition, contact lenses should not be worn during treatment.

Pregnancy

This remedy can be used during pregnancy, however, the girl should be regularly monitored by a doctor.

During breastfeeding, you should stop taking the drug. If for some reason it is impossible to refuse, then the use of the drug is allowed, however, natural feeding should be excluded.

Overdose

When using the drug Dex-Gentamicin, an overdose is unlikely. However, if it occurs, then symptomatic treatment is necessary.

Side effects

As a result of taking the medication, the patient may experience side effects, the occurrence of which must be reported to your doctor so that he can decide whether you can continue to use this drug or not.

Perhaps he will choose a safer analogue.

Side effects include conditions such as:

• The appearance of a burning sensation and itching. These conditions may occur immediately after instillation;
• Any allergic effects;
• A sharp increase in intraocular pressure;
• Clouding of the lens or blurred vision.

Compound

Dex-Gentamicin drops are colorless.

They contain active substances such as gentamicin sulfate, as well as dexamethasone sodium phosphate. The auxiliary elements are potassium hydrogen phosphate and benzalkonium chloride.

Pharmacology

Dex-Gentamicin is a topical glucocorticosteroid.

When used topically, dexamethasone quickly penetrates the tissue of the cornea and conjunctiva, producing the desired effect.

When used topically, gentamicin sulfate is detected in the eye structure after 6 hours.

Other

Dispensed by prescription.

The medicine should be stored out of the reach of children, at a temperature not exceeding 25 degrees.

You should also find out about the drug combination of Dexa-Gentamicin with other medications.

When taken simultaneously with atropine, cholinergic drugs, as well as drugs that cause mydriasis, a sharp increase in intraocular pressure can be observed.

When used topically, gentamicin is incompatible with amphotericin B, sulfadiazine, cloxacillin, heparin, and cephalothin. Ignoring this point may lead to the deposition of precipitates in the conjunctival sac.

Available in other dosage forms: eye drops.