What is included in the triad of temperature?

Indications for use

In fact, this remedy can always be used if an adult or child has a fever due to an inflammatory process, seasonal cold or flu. In addition, the triad for temperature is truly indispensable for other infectious diseases.

Today, there are many opinions about the effectiveness of this drug. Some people consider it indispensable, while others, on the contrary, think that it is more harmful than useful. In any case, if your body temperature rises to 38 degrees, do not rush to bring it down. The fact is that thanks to it, a hot environment is created in the body, which pathogens do not like. Harmful bacteria stop multiplying and die immediately if the patient’s body temperature rises to 38.5 degrees. In addition, some medications work more effectively only in this condition of the body.

It is necessary to bring down a high temperature: for congenital and acquired heart defects, if you have frequent fainting or convulsions, arrhythmia, for neurotic or mental disorders (epilepsy).

Homeopathic remedies for colds, runny nose, cough, flu

Every year we receive invitations to get a flu shot. But alas! The benefit of this vaccine is questionable at best, and it is potentially dangerous, especially for the most susceptible groups of the population - children and the elderly. The vaccines are made from strains that circulated in the past year. Accordingly, they cannot protect against the new strain that appeared this year. The best evidence of this is the admission by health authorities this year that the flu vaccine "didn't arrive." Can you guess what they recommended? Re-vaccination! Or maybe there is something better?

After many years of homeopathic practice, I believe that there is nothing easier than curing the colds and flus that plague us every year. There is no need for vaccination as a well-chosen homeopathic medicine will cure the flu within a few days if taken at the onset of the disease. Readers wary of remaining unvaccinated against influenza may be reminded of the success of homeopathy in treating the virulent Spanish flu pandemic in 1918. Studies conducted in British hospitals showed that those treated homeopathically had only 5 deaths. %, compared with 45% mortality among those treated with other drugs.

Let's say that this was before the discovery of antibiotics, but do medical authorities recommend antibiotics for the treatment of viral diseases like influenza? No. In patients with influenza stuffed with antibiotics, to all the troubles there are also problems of overgrowth of candidal fungi and increased resistance of microorganisms.

So how does a homeopathic doctor go about preventing and treating the annual flu? By examining 10 to 20 patients, we can identify the leading drug in the current epidemic. We record all the symptoms of these patients, and among them are immediately visible those that we call the main symptoms indicating a cure for this epidemic. The Asian flu, which began its invasion in December 1996, typically began with a sore throat, quickly progressing to extreme fatigue and muscle weakness (“like a truck had driven over me”), putting the patient to bed in a state of extreme weakness with a temperature of 39° C. The patient was in a state of stupor, he had neither thirst nor appetite, but had a severe headache. All these symptoms indicate Gelsemium

.
A patient taking GELSEMIUM
every two hours usually recovers from such flu on the same day, or at most within two days.
Place one grain of Gelsemium
200C in 100 ml of water, dissolve and take one tablespoon every two hours. People who are hypersensitive to medications, vitamins, etc., and those who are not familiar with homeopathy, are better off starting with a milder dose, 30C.

Patients who did not receive Gelsemium

, will move on to the second stage of this flu: an accumulation of viscous, stringy yellow mucus collecting in the sinuses and ears, and flowing down the back of the throat.
The remedy for this stage is KALI-BICH
, as is
Gelsemium
. Use the same dose, but dissolve the two medications separately in cups and give at least ten minutes apart.

“Wandering pneumonia,” as it is called in Western medicine, is the third stage of this particular flu. At this stage, a severe dry cough develops, aggravated at night and when lying down, so severe that I have had patients whose ribs were broken from such a cough. BRYONIA will bring immediate relief

, and you won’t need to take antibiotics.
For Bryonia
and
Kali-bich
, use dilutions of 30C or 200C, as for
Gelsemium
: dissolve one grain in 100 ml of water and take one tablespoon every two hours.

The cost of this procedure is one cent per day! Think about the schools that were forced to close because of this flu. What if during this epidemic each student received one teaspoon a day of Gelsemium

as a preventive measure, most students would never have caught the flu back then!
And this without any side effects. The world is not yet ready for such simple measures, but you, parents, can protect your children at home with a teaspoon of Gelsemium
200C per day.

So, Gelsemium

was most definitely the remedy for this epidemic. But this does not mean that the same drug will be effective for the next flu. What can you do to protect yourself from further flu illnesses now and in the future? With a well-chosen medicine, even long-term coughs and colds will disappear the first time. This is the magic of a minimal dose (a highly diluted homeopathic remedy).

I will present below common and frequently used remedies. All should be used in a potency of 30C (for sensitive patients) or 200C, one grain dissolved in 100 ml of water and given by teaspoon or tablespoon (for details see Well Kept Homeopathic Secrets in my previous newsletter, Vol. 2, No. 1) .

The most popular remedy for colds is ARSENICUM

. Any cold that begins with a runny nose with clear discharge can be stopped with several doses. It stops at an early stage colds in the form of sneezing due to changes in weather, and colds that begin in the nose and then tend to spread to the throat. The patient is restless, anxious, asks for cold drinks, usually in small sips. There is also often a burning sensation in the throat, which can be relieved by drinking warm drinks.

ACONITUM

has no equal for the sudden onset of a cold with high fever, usually starting at midnight. This often happens when a child frolics in the dry cold wind during the day. He then goes to bed without any symptoms, but suddenly wakes up around midnight screaming, restless, has a high fever that makes his whole body hot, and asks to drink cold water. It’s just a miracle how a couple of teaspoons of aconite lowers the temperature, and meanwhile the child falls asleep peacefully. The next morning the child wakes up as if nothing had happened. The storm of illness is calmed by the magic of aconite.

It happens that a child suddenly develops a high temperature (40°C) at about 15:00, the face becomes bright red, the limbs and body are icy. It felt like blood from all over my body had collected on my face. Huge pupils and a very strong headache. The child may have a wild expression on his face. If there is a cough, it will be a dry, tearing “machine gun” cough, sharp, intense, and repeated. BELLADONNA

relieves fever, headache and cough.

Let's talk about a completely different type of cold. Sometimes a patient will tell you that the constant flow of mucus down the back of the throat is causing a cough from the throat. He has difficulty removing sputum due to its stringiness and viscosity. When you do manage to spit it out, it is yellowish-green. “When it feels bad, take KALI-BICH!

" - this is our motto.
This sticky phlegm can also be the cause of sinus headaches or earaches that mimic acute ear infections in children, and for these conditions Kali-bich
also works well.

I recall the case of a woman whose illness always began with sudden chills and cough. One time she was unable to recover. This severe incessant cold got the better of her until I found out that her condition always worsened around 23 hours, she had a strong tickling in the throat, tenderness of the trachea from the inside and pain on any pressure from outside, and with a debilitating cough There was barely a little sputum coming out. Taken together, these symptoms pointed to RUMEX

, and this medicine magically brought life back to this woman.
After taking Rumex
, this suffocating cough and cold, which lasted two months, completely disappeared. Coincidence? This has happened too many times to be considered just a fluke. A well-chosen homeopathic remedy cures any common cold, chill or cough time after time.

Everyone knows how your eyes water when you cut an onion. Thus, you are dealing with natural homeopathy! ALLIUM CEPA

, red onion, indicated for colds with lacrimation; tears don't sting. Copious nasal discharge - flows like a tap; the skin under the nose is torn, red, with burning pain. The throat feels raw, and this sensitivity quickly spreads into the chest; the cough is worsened by inhaling cold air. Colds usually appear after exposure to cold, damp wind and are worse in the evening and in a warm room. If you have these symptoms, you will love red onions in homeopathic doses!

For hard, muffled coughs in addition to the already mentioned Belladonna

Every mother should have
SPONGIA TOSTA
. This miracle of nature, obtained from a sea sponge, is the number one remedy for croup and that painful, barking, dull cough that torments the patient day and night. The cough sounds like sawing wood, and the fear of suffocation due to a feeling of a plug in the throat is strong.

We have many more medicines used for cough, cold and flu, the choice depends on the features mentioned above. Observing your symptoms will help your homeopath find the right remedy, or you can find one for yourself in one of the many wonderful homeopathic books available in health food stores. When you have symptoms of illness, get better in one day, while others will be sick for weeks, and you will experience the power of homeopathy!

source

Pharmacodynamics

The classic version of the triad includes three main components: Analgin, No-shpa and Diphenhydramine. Therefore, we will consider the pharmacodynamics of each of them.

  1. Analgin. It contains metamizole sodium, which is a derivative of pyrazolone. The drug has a weak antipyretic, analgesic, and anti-inflammatory effect. Its mechanism is associated with inhibition of PG (prostaglandin) synthesis. 20-40 minutes after taking the drug, its pharmacological effect develops. Maximum effectiveness is achieved after two hours.
  2. No-shpa. The active ingredient is drotaverine, which is a derivative of isoquinoline. It has a powerful antispasmodic effect on smooth muscles due to inhibition of the phosphodiesterase enzyme. The latter is necessary for the hydrolysis of AMP and cAMP.
  3. Diazolin. The drug is an H1-histamine receptor blocker. It has an antiallergic effect and helps reduce swelling of the mucous membranes. Using this remedy, you can weaken the effect of histamine on smooth muscles, uterus, bronchi and intestines, reduce the severity of hypotension, and increase vascular permeability. Penetrates slightly into the central nervous system, but does not have a hypnotic or sedative effect. Anesthetic and M-cholinergic properties are weakly expressed. The effect is achieved 15-30 minutes after administration. Its duration can last up to 2 days.

Composition and release form

Troychatka consists of Analgin, Drotaverine and Diphenhydramine, which are available in the form of tablets and injections for injections. In some situations, the composition of the triad can be changed by replacing the components with analogues.

  • Drotaverine can be replaced by another antispasmodic agent, for example No-shpa or Papaverine. These drugs relieve pain in joints and muscles that appears at high temperatures.
  • Diphenhydramine , which is not available in pharmacies without a prescription, is an antihistamine - its action is aimed at blocking histamine H1 receptors. This drug can be replaced with other drugs that have a similar pharmacological effect - Tavegil, Dexamethasone or Diazolin. Diphenhydramine and its analogs relieve vasospasm, suppress inflammation and swelling of the mucous membranes.
  • Analgin , as the main component of the triad, also has analogues that help reduce temperature. The drug belongs to the group of antipyretic, anti-inflammatory and analgesic drugs. Analgin acts as a powerful analgesic that helps eliminate the discomfort that occurs at high temperatures. Often the drug is replaced with Toralgin, Metamizole sodium or Nobol.

Pharmacokinetics

Let's consider the pharmacokinetics of each drug that is part of the classic triplet recipe.

  1. Analgin. Completely and quickly absorbed immediately after oral administration. There is no unchanged metamizole in the blood. The drug is excreted by the kidneys. In this case, metabolites can be excreted in breast milk. Completely excreted in urine.
  2. No-shpa. Completely absorbed from the gastrointestinal tract after oral administration. But after metabolism during the first passage through the liver, 65% of the drug can enter the systemic circulation. After 45-60 minutes it reaches plasma.
  3. Diazolin. Due to the fact that the drug is absorbed quite quickly through the gastrointestinal tract, diazolin immediately penetrates the body tissues. Its bioavailability can range from 40% to 60%. The plasma half-life is 4 hours. It practically does not penetrate the blood-brain barrier. Metabolism takes place in the liver. The drug is excreted by the kidneys.

Triad composition depending on temperature

As mentioned above, troika for temperature is a combination drug. The classic composition of this remedy includes: No-shpa (in particular, the component drovaterin), diphenhydramine and analgin. But today, most manufacturers are trying to replace diphenhydramine (which can only be bought with a doctor’s prescription) with other antihistamines (Suprastin, Tavegil, Diazolin). In some cases, other components of the triad are also replaced. For example, No-shpa is often replaced by Papaverine, which has a similar effect.

An interesting fact is that all the drugs that are part of the triad, in fact, do not have an antipyretic effect, but together they help reduce body temperature to normal levels. Why is this happening? These products help your immune system fight bacteria. As a rule, at high temperatures, joints ache, pulse quickens, and headaches. Troychatka, with the help of its components, copes with these symptoms (analgin will relieve pain, papaverine or no-spa will relieve spasm of blood vessels and dilate them, diazolin will relieve tissue swelling).

Composition of the triad

The product has a combined composition, because it contains three medications. However, none are classified as antipyretic drugs. If you put them together, you can achieve a quick and lasting decrease in temperature.

So, today it is customary to include the following components in the triad:

  • Analgin - has pronounced anti-inflammatory and analgesic properties. The product also has a slight antipyretic effect.
  • No-spa – its active ingredient is drotaverine. Thanks to the presence of such a component in the composition, it is possible to achieve a noticeable antispasmodic effect, which mainly affects smooth muscles.
  • Diazolin - is responsible for blocking H1-histamine receptors. The presence of this component in the triad makes it possible to optimize the level of vascular permeability. This substance also helps cope with swelling of the mucous membranes.

The original composition of the triad includes diphenhydramine. This is a fairly serious substance that cannot be purchased without a prescription. Therefore, this medicine is often replaced with other drugs that have a similar principle of action. In addition to diazolin, these include suprastin and tavegil.

An antipyretic injection can also be performed in the absence of no-shpa. This substance can be replaced with other antispasmodics - for example, papaverine.

Thus, the triad simultaneously provides several actions - it reduces pain, promotes the dilation and relaxation of blood vessels, eliminates swelling of tissues and mucous membranes.

Troychatka from temperature for children

Diseases that cause fever are common in both adults and children. Children tolerate fevers worse. And, although many doctors do not recommend lowering the temperature to 38 degrees, parents often do this.

In such cases, a temperature three for children is very often used. In its composition, it is no different from the classic one (analgin, papaverine or no-spa and any antihistamine). In what cases can such a drug be prescribed to a child and how safe is it?

Doctors often prescribe intramuscular administration of triad to reduce high body temperature, regardless of what caused it (viral or bacterial infections). If you choose the right proportions, the combination of three separate drugs will help to quickly stabilize the temperature, relieve pain in the joints, and overcome headaches. But, if you give a triad injection to a child, you should remember that during inflammatory processes it helps to relieve the temperature only for three to four hours, after which the fever appears again. Due to the heavy load on the child’s body, triad can be administered no more than three times a day.

Remember, only a doctor can prescribe a fever test, especially if fever appears in young children. The danger lies in the fact that parents may choose the wrong dosage of drugs. If your child has a fever, you should call a doctor immediately and not self-medicate.

However, there are times when the baby has a high body temperature, and it is not possible to call a specialist. To prevent the occurrence of seizures, which can cause death, you must always keep a prepared triad or at least the drugs that are part of it (in any form) in your home medicine cabinet.

If your child is afraid of injections, you can make a microenema from the components of the triad, which will take effect within 5-10 minutes. But you should not abuse this remedy.

Composition, dosages and indications for use of the “troika” for temperature in adults and children

At first glance, it seems that the word “troika” hides a mysterious medicinal herb that saves you from high fever.

In fact, this is the “popular” name for an injection containing three active components at once.

For a pronounced effect, the following types of drugs are used: antipyretic, antispasmodic and antihistamine. The injection also has a more common name - lytic mixture.

Options for lytic mixture compositions for adults

The multicomponent drug can only be used by specialists in the provision of emergency medical care. Making the mixture yourself, and even more so replacing its components without the accompanying knowledge, is fraught with negative consequences.

Table 1. Composition of triad depending on temperature, recommended for adults

Compositions and dosages for children

To relieve fever in young patients, a lytic mixture with a similar composition is used. The fundamental difference lies only in the dosage of the multicomponent product.

Table 2. Triad dosage depending on temperature for children and adults

The troika for fever includes Papaverine, which is prohibited for use in treating children under 6 months.

The mixture can be prescribed to a baby with a fever only after reaching six months of age.

What tablets are included in the kit for home use?

Lytic mixture in tablet form is recommended for patients over 6 years of age. It should be noted that in this case, the medications will begin to act in about half an hour. In emergency cases, you should opt for an injection. What is included in the triad of temperature:

· 1/4-1/2 tablets of Analgin;

· 1/2-1 tablet No-shpa;

· 1/2 tablet of Diphenhydramine.

The composition of the triad based on temperature in tablets is similar for adults and children. The indicated amount is intended for therapy in adult patients.

It is not easy to choose the dosage of tablets for children in the triad for temperature. Usually, a quarter of each drug is mixed, crushed into fine crumbs and diluted with water. The resulting composition is given to the child to drink.

Indications for use of the lytic mixture

It is advisable to use the lytic mixture for severe fever.

The main indication for the use of triad is the thermometer value exceeding 39 degrees C.

In addition, the product is recommended for:

· ineffectiveness of tablet treatment (for example, high fever after taking Paracetamol);

· conditions that preclude oral administration (fainting, vomiting, child’s refusal to take the medicine).

Contraindications

Despite its obvious effectiveness, in some cases triad is contraindicated. In particular, the mixture is prohibited when:

· intense abdominal pain;

· if you have recently taken medications included in the lytic mixture;

· in case of individual intolerance.

Before injecting a fever test into an adult or child, the doctor will make sure that the fever is not associated with acute appendicitis. The injection will have a pronounced analgesic effect, which will significantly reduce the chances of seeking help in a timely manner.

If during the last 4 hours the patient has already taken Analgin, Diphenhydramine or Papaverine, then using the lytic mixture to relieve fever is prohibited. This can cause an overdose and worsen the condition.

Quite often, the main obstacle to using triad is individual intolerance to the components of the mixture. Allergies can take relatively harmless forms: itching, redness of the skin, sneezing. However, in some cases, the injection can provoke Quincke's edema, anaphylactic shock, and bronchospasm.

Possible side effects

Using triad at high temperatures sometimes leads to unpleasant phenomena.

Table 3. Possible side effects of the lytic mixture

Rubbing with vodka

Rubbing with vodka is considered a very popular way to reduce fever. The procedure is indicated only for values ​​above 39 degrees C. The method actually helps to temporarily improve the condition. However, rubbing with vodka is fraught with:

· vasospasm;

slow blood circulation;

· reduction of sweating.

As a result of applying vodka to the skin, the temperature of the latter decreases. The temperature of the internal organs increases due to vasoconstriction upon contact with cold liquid. Also, ethanol partially enters the body through the pores, which is especially undesirable for children and adolescents. Vodka vapor can cause coughing and sneezing.

Rubbing with vinegar

Vinegar is an acid, the penetration of which into the patient’s body is extremely undesirable. Do not rub dry skin with this aggressive liquid. It is better to wait until the patient sweats and the temperature drops on its own.

Often, vigorous rubbing with vinegar not only does not help to recover, but also forces doctors to prescribe medications to relieve vasospasm.

For your own good, you should forget about any rubbing during illness.

Antipyretics for children

Before using a temperature troika to relieve a child’s fever, it’s worth looking at what tablets and syrups are in your medicine cabinet. In most cases, the condition can be normalized by using softer and more gentle means.

Table 4. Antipyretic drugs for young patients

Do raspberries help with fever?

At the first sign of illness, grandmothers and mothers immediately run for homemade raspberry jam or fresh berries. It is believed that consuming the product along with tea will lower the temperature like a triad and increase immunity. Indeed, raspberries increase sweating, that is, the loss of heat by the body, but the hypothermic effect will not be pronounced.

Conclusion

1. Troikatka helps out at high temperatures even in critical cases. However, the complexity of drug dosing, the abundance of side effects and the presence of contraindications make the drug a real weapon against fever only in the hands of specialists.

2. Independent use of such treatment is fraught with worsening of the condition or the development of allergies.

3. As for therapy in children, triadic acid can often be replaced with safer syrups. The administration of three drugs turns out to be toxic and has side effects.

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Recipes

Only a competent specialist can make the correct three-piece, which will help bring down the high temperature in your particular case. The thing is that triad is made from three main components, which can be replaced with other drugs with a similar effect. For example, if Papaverine is not at hand, it can be replaced with Paracetamol, and Diphenhydramine with Suprastin or Diazolin. Analgin can be easily replaced with any painkiller. Sometimes only a doctor can choose effective remedies, especially when it comes to treating a child.

Russian recipe

But there is also our domestic recipe for triad, which was developed by Doctor of Medical Sciences V.A. Ivanchenko. Instead of walnuts, it contains tansy.

For oral administration, the herbs must be dried, crushed and mixed in a ratio of 4:1:2 in the sequence tansy - wormwood - cloves. For one dose, you need to clearly measure 1.75 g of the product.

On the first day you need to take one serving, and then gradually increase the amount over 2 weeks. It is best to take the “medicine” on an empty stomach.

These components not only have an antiparasitic effect, but will also help against high fever, colds, and also have an antimicrobial effect. After a course of taking such a simple and inexpensive remedy, even the condition of the skin improves, and rashes and pimples gradually disappear.

Triad dosage depending on temperature

First of all, you need to remember that the triad can only be used if the temperature has risen above 38 degrees. The injection will help you feel relief within 20 minutes; when taking tablets, you will need to wait up to 40 minutes.

The dosage of troika according to temperature always depends on the patient’s weight. If it is 55-60 kg, you can make the drug with 1 ml of Analgin, 1 ml of Diazolin and 1 ml of Papaverine (No-Shpy). If you decide to take pills, you must carefully study the instructions for them.

Remember that after three to four hours the temperature will begin to increase again, but the triad should not be used more than three times a day.

To normalize thermoregulation processes, an integrated approach is required. Conventional antipyretics do not always work effectively. The troika for fever, also called the lytic mixture, contains 3 components, which allows you to quickly reduce the temperature and eliminate the symptoms associated with it.

Operating principle

Not all components of the triad have an antipyretic effect.

  1. The main ingredient of the drug is analgin. This component successfully reduces temperature. In addition, it helps to cope with pain and body aches.
  2. Diphenhydramine enhances the antipyretic properties of analgin. In addition, the substance has pronounced antiallergic properties and helps cope with swelling of the mucous membranes.
  3. Drotaverine has a pronounced antispasmodic effect and helps dilate blood vessels. No-spa has a similar effect. It helps reduce blood pressure, cope with spasms and dilate blood vessels.

These substances help increase heat transfer. This helps enhance the effect of analgin on the body. The use of triad significantly improves the patient’s condition even in the presence of high fever.

The undoubted advantage of the mixture is the possibility of use if the patient is not able to take a pill. This need appears when there is a strong urge to vomit. It may also be associated with fainting or the patient's refusal to take medications.

Injection administration of triad is used exclusively at high temperatures - more than 38 degrees. Using the composition more than 2 times a day is strictly prohibited. It is important to consider that triad is considered a fairly strong substance. Therefore, it should be used extremely carefully.

The use of medications that are present in the triad helps to quickly reduce the temperature. If inflammation is just beginning to develop, the composition will reduce the temperature readings for several hours, after which they will increase again. That is why the triad can be used exclusively as part of complex therapy.

Indications for use

When the temperature rises, various symptoms occur, depending on the degree of hyperthermia. Without timely assistance, a person’s condition may deteriorate significantly, and serious complications may subsequently arise. Troychatka relieves symptoms, regardless of the cause of their occurrence - flu, colds, inflammatory processes. Pink hyperthermia is characterized by weakness, drowsiness, the skin turns red, becomes hot, and sometimes tachycardia develops. To relieve symptoms and reduce temperature, it is enough to take an antipyretic drug.

With white hyperthermia, vascular spasm occurs, so the limbs become cold and the skin becomes pale. Shortness of breath appears, the heart rate increases, the person becomes delirious, very excited, and convulsions are often observed. The problem often appears in underweight infants. To eliminate it, a triad is used.

When you need to urgently reduce your temperature:

  • fainting, clouding of consciousness, convulsions;
  • increased heart rate, heart rhythm disturbances;
  • heart defects of various origins.

Important! In the absence of seizures, doctors recommend lowering the temperature when the readings reach 38.5 degrees or more. They should be knocked down with the help of a triad when values ​​rapidly increase and pathological processes develop. This will help avoid overload of the heart, blood vessels, and exhaustion of the body.

Components

Troychatka has a triple effect on the body, since it contains antipyretic, antihistamine components, and antispasmodics. All drugs have a low price and can be purchased at any pharmacy without a prescription.

Important! Troikatka effectively helps with high temperatures; it is an indispensable tool for helping a sick person in emergency situations. But the drug is not an absolutely safe medicine; it is necessary to carefully calculate the dosage of each ingredient during preparation in order to avoid dangerous consequences.

The main antipyretic ingredient is selected taking into account the patient’s age and history of chronic diseases. For a child, the ideal option is Paracetamol - the medicine is safe even for newborns, side effects occur only with long-term use of the medicine. Ibuprofen acts faster, but causes negative reactions in children more often. Adults can use acetylsalicylic acid, as well as drugs such as Nimesulide, Analgin, as drugs to reduce fever.

Important! Nonsteroidal anti-inflammatory drugs should not be used for ulcers, erosions of the digestive tract, decreased blood clotting, or a tendency to bleed. Derivatives of acetylsalicylic acid are strictly contraindicated for the treatment of children.

Antispasmodics

Antispasmodics are introduced into the triad to improve the functioning of central and peripheral vessels. No-spa has a mild antipyretic effect, helps relax smooth muscles and the walls of internal organs, and is more effective on deep vessels than on peripheral ones.

Important! Antispasmodics can sharply reduce blood counts and provoke disturbances in the functioning of the heart.

Antihistamine

Drugs with an antihistamine effect eliminate swelling of the mucous membranes and reduce the risk of allergies to waste products of pathogenic microorganisms. List of effective drugs for blocking histamine synthesis - Suprastin, Tavegil, Diazolin.

The medications that are included in the troika prescription act together quickly, a decrease in temperature is observed within 35–50 minutes after administration - white hyperthermia turns into pink, which is safer for the body. You just need to regularly measure your temperature, drink more fluids, and ventilate the room.

Proportions of the drugs that make up the triad:

Name of medicineFrom what age can it be used?Maximum allowable dosage
Ibuprofen tabletsFrom 6 years old0.2 g for children under 12 years of age, 0.4 g for adults.
Ibuprofen suspensionFrom six months2.5 ml for children up to 12 months;
5 ml – up to 3 years;

7.5 ml – 3–6 years.

Paracetamol (tablets/oral solution)From 1 month0.01g/kg – children 1–3 months;
0.06–0.12 g/2–5 ml – up to a year;

0.1–0.25 g/5–10 ml – up to 5 years;

0.2–0.5 g/10–20 ml – 5–12 years;

500–1000 mg – children over 12 years old, adults.

No-shpaFrom one year0.01 g – up to 3 years;
0.02 g – 3–5 years;

0.04 g – 6–12 years;

0.08 mg – over 12 years old, adults.

PapaverineFrom 6 months5 mg – up to 2 years;
5–10 mg – 2–4 years;

10–15 mg – 5–10 years;

20 mg – 11–15 years;

3–4 tablets – teenagers and adults.

SuprastinFrom 1 month0.25 tablets – up to 3 years;
12.5 mg – 3–14 years;

1–2 tablets – over 14 years old, adults.

Instructions for use: first take an antipyretic, then an antispasmodic and an antihistamine. Take all tablets separately, with a small amount of purified still water.

Important! If the condition does not improve within 60–80 minutes after using the triad, you must call an ambulance. Experts use the classic recipe of the triad - Analgin (2 ml), No-shpa (2 ml), Diazolin or Diphenhydramine (1 ml) in the form of solutions for intramuscular injections. With intramuscular administration of the mixture, the condition will quickly improve.

Troychatka is an effective multi-component remedy, which significantly increases the risk of allergies and negative reactions. You should not drink the triad or give an injection if you are hypersensitive to the components of the medicine.

The drug is contraindicated for severe abdominal pain of a cutting or wandering nature, tension in the abdominal wall - such symptoms often occur during an attack of appendicitis. Any medications only blur the clinical picture, which makes diagnosis much more difficult.

Troychatka with Analgin cannot be taken during pregnancy, the optimal prescription for expectant mothers is Suprastin, No-shpa, Baralgin, but it is better to first consult with a gynecologist or therapist. The combination drug is also contraindicated during lactation.

Troychatka is an effective drug against high fever, which has a complex effect on the body. When using medicine in the form of tablets or injection solutions, the proportions must be strictly observed to avoid overdose. The combination of drugs is suitable only for emergency care; it cannot be used for a long time.

To normalize thermoregulation processes, it is sometimes necessary to use complex treatment. Traditional antipyretic drugs are not always able to quickly provide the required effect; in these cases, you should use a recipe developed on the basis of a mixture of drugs with different effects - a triad for temperature.

Content:

Troikatka from temperature: composition in tablets, injection proportions and dosage for adults and children

Troychatka (also called “lytic mixture”) is an emergency remedy to eliminate the manifestations of influenza, ARVI and other diseases of inflammatory origin, accompanied by a significant increase in body temperature.

Such a multicomponent drug is not intended for self-medication, but it is important to have information about the indications, possible contraindications and adverse reactions, as well as methods of using the antipyretic.

Medicines included in Troychatka

The constituent components of the triad belong to three pharmacological groups and have the following properties:

  • Antipyretic. Analgin is a drug based on sodium metamizole, which also demonstrates analgesic, anti-inflammatory, and analgesic effects. It is a derivative of pyrazolone, which inhibits the production of substances that cause inflammatory reactions in the body. Under the influence of the active component, there is a slight effect on water-salt metabolism (retains sodium and water in tissues), an increase in heat transfer, and prevention of pain impulses.
  • Antispasmodic. Drotaverine (the active component of No-Shpa) is a myotropic antispasmodic, similar to papaverine, but is more effective and lasting. There is a decrease in the tone of the smooth muscles of internal organs and their motor activity, providing a vasodilating effect (relaxation of smooth muscles in the walls of blood vessels).
  • Antihistamine. Diazolin is a substance with antiallergic properties that reduces swelling of the mucous membrane and weakens the effect of histamine.

The composition for children and adults is the same, but only the doctor makes the decision to replace individual components of the mixture.

How to replace this or that drug

As a replacement for No-Spe (Drotaverine), Papaverine can be considered, and Diphenhydramine - Suprastin or Tavegil.

Analgin can be replaced with Paracetamol or another NSAID drug with antipyretic and anti-inflammatory properties.

Injection dosages for adults and children

When preparing Troychatka in the form of an injection solution, the use of active ingredients in the following proportions is required:

  • 2 ml of metamizole sodium (Analgin).
  • 2 ml No-Shpa.
  • 1 ml Diphenhydramine.

The indicated dosages are suitable for preparing Troychatka from fever for an adult weighing 55-60 kg.

It is more difficult to choose the dosage of triad for children; for example, Analgin is calculated exactly according to body weight, and Diphenhydramine according to age. In tablet form, the proportions will be easier to maintain (more on this below), however, taking Demidrol in tablets is possible only from 7 years of age, and in injections from 7 months.

When replacing medications, the proportions and volume of medications must be discussed with your doctor in advance.

Dosage adjustment depending on age

"Analgin."

If the injection solution is used for a long time (more than 1 week), it is necessary to monitor the peripheral blood picture and liver function.

For adults:
  • 1-2 ml (50% solution).
  • The frequency of administration is no more than 3 times a day.
  • The maximum daily dose is 2 g.

Dosage for children:

  • Under 1 year: exclusively for intramuscular administration.
  • The duration of treatment is no more than 72 hours.
  • Over 12 months: the dose is calculated as follows: 0.1-0.2 ml/10 kg body weight. Frequency of administration – up to 3 times a day.
"Drotaverine".

Particular care is required in the treatment of patients with atherosclerosis of the coronary arteries, as well as arterial hypotension.

For adults:
  • Single dose: 40-80 mg.
  • Frequency of administration – up to 3 times a day.

For children:

  • Under 6 years old. Single dose 10-20 mg.
  • 6-12 years: 20 mg.
  • Frequency of administration – up to 2 times a day.
"Diphenhydramine."

During the entire period of using the medicine, you should refrain from exposure to direct sunlight, as well as drinking alcohol.

Children:
  • 7-12 months: 3-5 mg.
  • 1-3 years: 5-10 mg.
  • 4-6 years: 10-15 mg.
  • 7-14 years: 15-30 mg.

Frequency of administration: up to 3 times a day.

Adults:

  • 10-50 mg up to 3 times a day.
  • The maximum daily dose of 200 mg should not be exceeded.

Only a doctor can select the appropriate dosage, taking into account the patient’s age, the characteristics of his body, and the possibility of using one or another component.

How to give an injection correctly?

The doctor must be informed about what medications the patient has taken over the last 24-48 hours (including those with antipyretic, antispasmodic, and antiallergic properties).

To prepare an injection solution, all active components of the mixture are injected into the gluteal muscle.

  • It is necessary to first warm the ampoule in your palms.
  • Use a disposable syringe for administration.
  • Take the medicines with a syringe one by one: first Analgin, then Drotaverine and lastly Diphenhydramine.
  • Disinfect the injection site (the upper quadrate of the gluteal muscle is best) with alcohol.
  • The needle is held at an angle of 90 degrees to the surface of the buttock and inserted to 2/3 of its length.
  • Squeeze out the contents of the syringe slowly, the injection of the triad is painful.

After administration of the drug, the patient will feel relief within 15-20 minutes. The pharmacological effect lasts for 3-4 hours, after which the temperature will begin to rise again. The lytic mixture should not be used more than three times a day.

Dosages in tablets for adults and children

The injection solution can be replaced with an oral form. The triad contains 1 tablet of Analgin, No-Shpa, and Diphenhydramine. After taking the tablets, improvement occurs within 30-40 minutes.

The drugs are washed down with a sufficient amount of water, following the instructions regarding the dosage regimen.

"Drotaverine"Children:
  • Under 6 years old. Single dose 10-20 mg.
  • 6-12 years: 20 mg.
  • Frequency of administration – up to 2 times a day.

Adults:

  • Single dose: 40-80 mg.
  • Frequency of use – up to 3 times a day.
"Diphenhydramine" Children:
  • 7-14 years: ¼ – ½ tablet up to 3 times a day.

Adults:

  • From 14 years: ½ - 1 tablet up to 3 times a day.
  • The maximum daily dose is 250 mg.
"Analgin" Children, up to 3 times a day:
  • 2-3 years: 50-100 mg.
  • 4-5 years: 100-200 mg.
  • 6-7 years: 200 mg.
  • 8-14 years: 250-300 mg.

Adults:

  • 250-500 mg three times a day.
  • The maximum daily dose is 3 g.

Important:

The dosage for children and adults is selected taking into account the age and individual characteristics of the patient’s body. A preliminary consultation with a pediatrician or therapist is required.

Drug interactions

It must be taken into account that Diphenhydramine interacts with the following substances:

  • Enhances the effect of ethanol and medications that depress the central nervous system.
  • Combination with drugs from the group of psychostimulants is undesirable.
  • Reduced effectiveness of drugs that contain apomorphine (if the substance is used to stimulate the gag reflex in case of poisoning).

Drotaverine can also enter into drug interactions:

  • When combined with drugs from the group of tricyclic antidepressants, as well as medications based on quinidine and procainamide, a decrease in blood pressure is observed.
  • Helps reduce the spasmogenic activity of morphine.
  • Reduces the antiparkinsonian effect of levodopa.
  • Enhances the effect of medications that are part of the group of antispasmodics (for example, Papaverine).

If you combine the use of Drotaverine with drugs that contain phenobarbital, an increase in antispasmodic properties is observed.

The combination of Analgin with other substances from the NSAID group can provoke a mutual increase in the toxic effect on the patient's body.

If a person takes tricyclic antidepressants and oral contraceptives, there is a disturbance in the metabolism of Analgin and an increase in its toxic effect.

Simultaneous use with sedatives and tranquilizers increases the analgesic properties.

Using Troychatka during pregnancy

All components of Troychatka during pregnancy are used with extreme caution:

  • Analgin: especially during the 1st trimester and the last 6 weeks.
  • Diphenhydramine and Drotaverine: only in case of objective indications for use, taking into account the possible benefits and potential risks for the child.

When treating during pregnancy, safer single-component drugs in a suitable dosage form are considered.

Pregnant women should not self-administer the lytic mixture in any of its dosage forms.

Indications for use of triad

An increase in body temperature can develop in two ways. Pink hyperthermia involves the appearance of general lethargy and drowsiness, loss of strength, redness and heating of the skin, and the development of tachycardia, proportional to the increase in temperature and severity of the condition.

White hyperthermia is characterized by coldness of the palms and feet, the appearance of a pale, bluish or marbled skin tone and shortness of breath, the development of high-grade tachycardia (regardless of the temperature increase), delirium and agitation. The condition is also dangerous because it can lead to seizures.

White hyperthermia occurs in premature babies, as well as in the presence of a hereditary predisposition. Spasm of peripheral vessels is of great importance in its development. It is this that makes taking conventional antipyretics ineffective.

To relieve vasospasm and reduce temperature during white hyperthermia, a complex of medications, the so-called triad, is used. It consists of three important components: antipyretic, antispasmodic, antihistamine.

In most cases, antipyretic medications are not recommended for use until the temperature rises to 38.5°C. It should be knocked down with the help of a triad in the case of the development of pathological processes and a progressive increase in indicators, since in such a situation there is a risk of overloading the cardiovascular system and exhaustion of the body.

Pathological processes requiring urgent measures to reduce the temperature to 38.5°C:

  • fainting, seizures or a tendency to develop such conditions;
  • cardiac dysfunction;
  • congenital and acquired heart defects, arrhythmia;
  • low stability of the nervous system (schizophrenia, epilepsy, risk of developing cerebral edema).

Troikatka for fever is not a safe remedy and requires a high level of responsibility when calculating the dosages of its constituent drugs and applying them in practice. At the same time, the high efficiency of the mixture makes it extremely relevant for emergency assistance in the development of severe hyperthermia. It can not only quickly normalize the temperature curve, but also provide a significant analgesic effect.

Indications for use

The use of the medicine is advisable for any condition that is accompanied by an increase in body temperature. However, it is important to follow the rule - it is not recommended to lower the temperature if it has not risen above 38-38.5 degrees, since such an increase in itself is critical for many microorganisms.

Taking the combined drug is allowed in the following conditions that occur with an increase in thermometer readings:

  • acute infectious diseases and inflammatory processes;
  • attacks of heart rhythm disturbances;
  • fainting or convulsions caused by fever;
  • in the postoperative period;
  • as part of the treatment of muscle and stomach pain, migraines, as well as pain arising from urolithiasis and ailments affecting the genitourinary system;
  • for neurotic disorders;
  • epileptic seizures;
  • to relieve symptoms and prevent the development of a hypertensive crisis (the method is used by doctors at ambulance stations and in medical hospitals);
  • critically elevated blood pressure (in this case, an intramuscular injection is necessary);
  • diseases of the cardiovascular system;
  • for acute allergic reactions with asthmatic complex. The action of the active components of the medicinal mixture is aimed at reducing the activity of the allergic reaction and suppressing symptoms: fever, headache, itching, breathing problems, etc.

Antipyretic component of the triad

Ibuprofen or paracetamol are most often used as an antipyretic drug for children. They are well tolerated and produce virtually no side effects. To reduce fever in adults, analgin, nimesulide, aspirin or derivatives of these drugs are also suitable.

Paracetamol is approved for use from the first months of life; its adverse effect on the condition of the kidneys and liver can manifest itself in most cases only with long courses or consumption of significant doses of the drug. Ibuprofen is a more effective antipyretic, but it has all the negative qualities of non-steroidal anti-inflammatory drugs.

Warning:

The development of erosions, ulcerative lesions of the digestive system, as well as pathologies of the blood coagulation system and the appearance of bleeding are contraindications to the use of paracetamol, ibuprofen and other drugs in this group.

Video: Dr. E.O. Komarovsky on the use of paracetamol and aspirin to relieve fever in children

Method of using triad

Instructions for use indicate that the drug should be used approximately 15-20 minutes before meals. The body must be gradually accustomed to this procedure. The toxic components of the substance usually affect helminths very quickly. As a rule, only 1-2 applications of the triad are sufficient, but even if the patient has achieved the desired effect, it is better not to stop therapy. The course must be completed in full. There will be no harm to the body after such treatment if, of course, the person has studied all possible contraindications.

On day 1 of use, drink 1 serving of triad. On day 2, the portion should be increased exactly 2 times. On day 3 - 3 servings. On all subsequent days it is necessary to use 3 servings.

Compared to traditional anthelmintic drugs, treatment with triad requires a longer course. At the same time, the collection does not have as many side effects as are present in tablets. Wormwood and tansy are not used to treat pregnant women, nursing mothers and infants. The active substances contained in the decoctions increase the tone of the uterus and can negatively affect the baby’s body.

Antispasmodics in the triad

Antispasmodics are necessary to normalize the condition of peripheral vessels. Among them, the most popular is papaverine or nikoshpan, which contains, in addition to the specified active ingredient, nicotinic acid, which complements the positive effect of the main component.

No-spa, recommended in some recipes for troika for temperature, contains drotaverine as the main active compound. It is useful for relieving spasms of smooth muscles of deep vessels and internal organs, but its effect on peripheral bloodstreams is minimal.

The dosage of drugs is calculated based on the amount of active substance in the tablet or capsule. Usually it is 0.04 g. In the triad complex, it is enough for an adult to take 1-2 tablets.

For children, no-shpa is divided using 0.25-0.5 tablets, depending on age. The children's dosage of papaverine is 0.01 g of the active substance, is available separately and allows you to accurately measure the required amount of the drug.

Medicines in this group can have a hypotensive effect on the body and provoke cardiac conduction disorders. Patients with atrioventricular block should be careful when using them as part of the triad.

Warning:

Nicospan is not used to reduce body temperature in children, as it can cause a hypersensitivity reaction and increase the sensation of heat.

Dosage of lytic mixture for children with fever

dosage of lytic mixture

Troychatka for fever should be given carefully, because the drugs, in addition to their benefits, can cause harm.

In ampoules

A troika injection for fever works much faster than pills, because the medicines immediately enter the bloodstream and begin to act. In addition, at high temperatures, vasospasm is possible, in which a tablet from the stomach (or a rectal suppository from the rectum) may not be immediately absorbed.

The dosage of triad is determined individually depending on the age and weight of the child. For patients up to 12 months, the dose is calculated by weight, and after - by age:

  1. Analgin or other means to reduce fever should be dosed at the rate of 0.2 ml for every 10 kg of the patient’s weight.
  2. Antihistamine (Suprastin or Diphenhydramine) - 0.1 ml for each year of the child’s life.
  3. Antispasmodic - 0.1 ml for each year of life.

For example, if a child is 4 years old and weighs 20 kg, then 0.4 ml of Analgin, 0.4 ml of Suprastin and 0.4 ml of No-shpa will be required.

In tablets

In the form of tablets, a lytic mixture for children is prescribed if there is no vasospasm, otherwise there is a risk that the drugs may not be absorbed. For young children, 3 tablets are crushed into powder and given with plenty of water. The tablets begin to act after 30-50 minutes. The child will feel a little better and will fall asleep.

The dosage in tablets is calculated depending on the age of the patient. Children under 5 years of age are prescribed ¼ tablet, regardless of the composition of the lytic mixture. It is best to use Paracetamol, Analgin and No-shpu, because this combination is considered classic and harmless. If these drugs are not available or cannot be taken for some reason, then the composition of the triad may include Baralgin, Suprastin, Papaverine.

Antihistamine component of the triad

Agents with antihistamine action can reduce the severity of swelling of the mucous membrane and the body's sensitivity to pathogens and their metabolic products, reducing the risk of developing an allergic reaction. The most popular first-generation drugs for this purpose are:

  • suprastin;
  • diphenhydramine;
  • tavegil;
  • pipolfen.

The dosage of the medicine depends on the age of the patient. It is not required to increase it due to the development of certain symptoms of white hyperthermia.

Features of the use of triad for hyperthermia

The drugs included in the triad in the form of tablets manifest their effect after 30-40 minutes. In this case, white hyperthermia turns into pink, which is a less dangerous condition and requires only monitoring body temperature indicators and adequate care for the patient.

Further actions to normalize the patient's condition and reduce body temperature usually include non-drug measures aimed at increasing sweating. Drinking plenty of fluids and maintaining adequate temperature in the room are also important.

If the onset of a beneficial effect is delayed, it is necessary to call an ambulance. As a rule, doctors administer a lytic mixture consisting of drugs from the same groups intramuscularly as an injection.

The dosage of each component of the triad based on temperature for a single dose is calculated separately according to the age and body weight of the patient. Their proportions relative to each other are not used.

What is a triad

The combination of three effective components in the correct proportion leads to normalization of body temperature and the disappearance of associated symptoms.

The triad contains the following active substances:

  • Analgin - performs an antipyretic function and relieves aches in muscles and joints;
  • Drotaverine – relieves spasms and pain;
  • Diphenhydramine - has antihistamine properties, relieves swelling of the mucous membrane, and also enhances the effect of Analgin.

If necessary, the doctor can replace some components of the drug. For example, in case of individual intolerance to Drotaverine, it is replaced with No-shpu or Papaverine. No-spa, among other things, promotes the expansion of peripheral blood vessels in the skin and reduces blood pressure, as a result of which the body’s heat transfer increases and overall well-being improves.

Diphenhydramine cannot be purchased at a pharmacy without a doctor's prescription, so it is often replaced with other antihistamines - Tavegil or Diazolin.

Dosage of drugs in the triad (table)

A drug Age Maximum single dose
Antipyretic component
Ibuprofen (tablets) 6 (over 20 kg)-12 years
Over 12 years old, adults
Ibuprofen (suspension) 6-12 months (7-9 kg)
1-3 years (10-15 kg)
3-6 years (16-20 kg)
6-9 years (21-29 kg)
9-12 years (30-40 kg)
Paracetamol (tablets) 10 mg/kg body weight
Adolescents and adults weighing >60 kg 0.5 g (maximum single dose can be increased to 1 g)
Paracetamol (suspension) no more than 10-15 mg/kg body weight
Antispasmodics (given for cold extremities)
No-shpa (tablets) 10 mg (¼ tablet)
20 mg (½ tablet)
40 mg (1 tablet)
over 12 years old, adults 80 mg (2 tablets)
Papaverine (tablets) 6 months - 2 years 5 mg (½ tablet)
5–10 mg (½–1 tablet)
10 mg (1 tablet)
10-15 mg (1.5 tablets)
15-20 mg (1.5-2 tablets)
from 15 years and adults 40 (4 tablets)
Antihistamine component
Loratadine (tablets) 3-12 years (up to 30 kg) 5 mg (½ tablet)
from 12 years (weight more than 30 kg) and adults 10 mg (1 tablet)
Suprastin (tablets) ¼ tablet
½ tablet
7-14 years and older, adults 1 tablet

Contraindications

The use of triad can be dangerous in the following cases:

  • presence of allergies to the components of the lytic mixture;
  • taking diphenhydramine or analgin the day before;
  • pain in the peritoneum, which may indicate the development of acute abdominal syndrome.

The composition of the drug to reduce body temperature during pregnancy and breastfeeding should be agreed with a specialist. Thus, analgin is prohibited for use during this period; there may be other contraindications and restrictions.

The triad for relieving hyperthermia can only be used in severe cases when the patient needs emergency medical care. Its use to reduce high body temperature in children should be done only with the permission and under the supervision of a pediatrician in the dosages indicated by him.

Video: “School of Life”: tips for reducing fever using folk remedies

Diphenhydramine and papaverine remain the most commonly used drugs, which is associated with the low cost of drugs and the rapid onset of effects. Moreover, along with them, analgin is used, which is part of the “triad” injection. This mixture is used in a medical hospital and in the emergency department. The “triad” is administered intramuscularly, which allows the onset of the desired effect to be accelerated.

The “triad” is used in surgical, trauma, and therapeutic patients. The injection composition, due to analgin, has a mild analgesic effect and is also effective against fever. Diphenhydramine is a blocker of histamine receptors in the periphery and is used as a central sedative. Papaverine is a strong antispasmodic with a predominant effect on vascular smooth muscle.

The combination of drugs in the “triad” is considered universal for providing first aid in the case of many pathologies. For surgical diseases, papaverine with diphenhydramine and analgin helps relieve pain by relaxing the muscles of the ducts, areas of the urinary tract and intestines. Due to diphenhydramine, it is possible to significantly alleviate the symptoms of acute surgical, urological and gynecological pathologies. It helps to calm the patient. Analgin can replace aspirin if it is available in the form of an injection solution.

In a therapeutic hospital and in the emergency department, in an ambulance and in paramedic and obstetric centers, the “troika” can be used to relieve a hypertensive crisis and to relieve anxiety. Papaverine is used to lower blood pressure in the triad. It very gently corrects blood pressure by relaxing muscular arteries. They are located on the periphery, which means that the action of papaverine improves blood supply to peripheral tissues without disrupting blood flow in the brain, kidneys, and heart.

In most regions of the country there are no large hospitals with special allergy departments. As a result, patients with allergic diseases are admitted either to therapeutic hospitals or to the intensive care unit. However, the first stage of their hospitalization is the emergency room or emergency room. Here, the “troika” can be used to reduce the activity of the allergic reaction. Due to the presence of diphenhydramine, the mixture reduces the risks for the patient in case of a systemic allergic reaction.

Composition of the triad, dosage of drugs

The triad contains three pharmacological drugs, which are extremely cheap, have a relatively small number of side effects, and also have a rapid onset of effect. These include analgin, diphenhydramine and papaverine.

Attention! Doctor's consultation required!

The dosage of analgin in the mixture is 2 ml of a 50% solution. The dose of diphenhydramine is 1 ml of a 1 percent solution. Papaverine dosage – 2 ml – 2% solution.

The drug analgin is not used in Western countries due to the large number of adverse reactions and because it is not economically profitable for pharmaceutical companies. It belongs to the class of non-steroidal anti-inflammatory drugs and has many analogues. One of them is aspirin. Both drugs have many adverse reactions associated with inhibition of 2 types of cyclooxygenase. However, to reduce fever, analgin and aspirin remain excellent means.

The drug diphenhydramine belongs to the class of histamine receptor inhibitors and is listed among the first generation drugs. In fact, diphenhydramine is already outdated and is not the most effective for the treatment of allergic diseases.

This is due to the suppression of nervous activity at the highest level. After taking diphenhydramine, the vast majority of patients experience drowsiness. For this reason, the “troika” is not an effective means of permanent treatment of allergies, although it can be used at the initial stage of development of a systemic reaction: urticaria, anaphylactic shock, angioedema.

A complete drug that does not have a central effect is loratadine, known by the trade name Claritin. This drug belongs to the class of second generation histamine blockers. In the same category for the treatment of allergies there is fenkarol, peritol, diazolin, simplex. The most effective at the moment are representatives of the third generation of histamine receptor blockers: cytirizine, desloratadine, fexofenadine. Moreover, loratadine remains one of the most commonly used drugs for the treatment of all types of allergies.

Papaverine, as part of the triad, acts as an antispasmodic agent, which is most active in relation to the vascular muscles. An intramuscular injection leads to a decrease in blood pressure, relaxation of the smooth muscles of the intestines, the sphincter of the gallbladder, the major duodenal papilla, and the ureter. Moreover, the functional analogue of papaverine is “No-shpa”.

This drug contains drotaverine, which is more active against the smooth muscles of internal organs rather than blood vessels. No-spa is used in surgical, therapeutic and gynecological practice. Due to the relaxation of smooth muscles, drotaverine and papaverine are able to relieve pain. They are not superior to novocaine in terms of potency, but they eliminate the cause of pain, which is why they are chosen for treatment much more often than other drugs.

Preparation proportions and dosage

Before you make a triad, you definitely need to familiarize yourself with the proportions. This is a fairly serious product, in the manufacture of which you need to follow basic recommendations.

To prepare an effective composition, you need to follow the following sequence of actions:

  1. Warm the ampoules in your palms. Before drawing liquid into a syringe, they must be disinfected.
  2. Draw up the medicine into the syringe. In this case, it is important to observe the proportions of the triad: 2 ml of analgin and no-shpa, 1 ml of an antihistamine - diphenhydramine or diazolin.
  3. Inject the drug. The triad is always inserted into the same place - the upper sector of the buttock on the left or right.
  4. The syringe needle must be held clearly perpendicular.
  5. When the needle is inserted 2/3 of the way, the mixture should be slowly squeezed out of the syringe. This process is accompanied by noticeable pain.

The dosage in tablets is much easier to follow. Adult patients are recommended to take 1 piece of each drug with a large volume of clean water. For children, the amount of medication is selected depending on weight and age category.

It is important to consider that it is strictly forbidden to inject the lytic mixture after using analgin. In case of an overdose of this substance, there is a risk of nausea, vomiting, and convulsions. Sometimes people lose consciousness and even fall into a coma.

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