Characteristics of Dioxidine
It is a synthetic antibiotic with a broad bactericidal effect. It is especially active against anaerobes, which is of great importance in the treatment of purulent diseases.
Dioxidin and Dexamethasone enhance the effectiveness of treatment of ENT diseases and help avoid complications.
Effective against the following pathogens:
- Klebsiella;
- staphylococci;
- dysentery and Pseudomonas aeruginosa;
- streptococci;
- Vibrio cholerae;
- Koch's wand.
Dioxidin is a synthetic antibiotic with a broad bactericidal effect.
The effect of the drug is characterized by the suppression of the vital activity of pathogenic flora and the destruction of bacterial cell membranes. It is quickly absorbed when applied topically, helping to cleanse purulent wounds and heal tissue.
Joint effect
Thanks to complex use in the form of a mixture, it enhances:
- anti-inflammatory effect;
- decongestant activity;
- bactericidal effect;
- resistance to allergens.
Dexamethasone is intended to normalize mineral, protein and carbohydrate metabolism.
It has a desensitizing effect on the body.
Indications for simultaneous use
Complex drops are prescribed for protracted nasal diseases, including those associated with atrophic processes.
Indications for use are:
- low efficiency of a monocomponent product;
- deterioration of the clinical picture while following prescribed therapy measures;
- transition of the disease to the chronic stage;
- the need for complex use of means of different actions;
- mixed etiology of the disease (addition of infection, bacterial infection against the background of allergies or viruses).
Simultaneous use of drugs is prescribed for severe stages of ENT diseases, including those with purulent inflammation. The products help relieve swelling and allergic reactions.
The products help relieve swelling.
Indications for use
Depending on the form of release, this product may have different indications for use. Dexamethasone tablets can be used for the following diseases:
Inflammatory processes of the thyroid gland.- Serum sickness.
- Asthmatic conditions.
- For bronchitis.
- Ophthalmopathy, which is at the stage of active progression.
- Different stages of connective tissue disease.
- In case of exacerbations of rheumatoid arthritis.
- Eczema in its most advanced forms.
- In the presence of malignant neoplasms, the drug can be used symptomatically.
- In case of acute deficiency of thyroid hormone (hypothyroidism), etc.
Dexamethasone in the form of ampoules is used in the following cases:
In states of shock. This includes various types of shock, including burn, toxic, traumatic, surgical, etc. If the cause of shock is the ineffectiveness of therapy with plasma replacement drugs or drugs aimed at narrowing blood vessels.- Brain edema, which also includes tumors, various injuries, cases of hemorrhage, meningitis, etc.
- Allergies in the most severe forms and cases of anaphylactic shock.
- An asthmatic condition when severe cases of bronchospasm and exacerbation of chronic obstructive bronchitis are observed. The medicine is also taken for bronchial asthma.
- Diseases of an endocrine nature, which include acute adrenal insufficiency, subacute thyroiditis, congenital forms of adrenal hyperplasia.
- Malignant tumors. This drug is used in the treatment of lymphoma and leukemia in adults, acute manifestations of leukemia in children, hypercalcemia in patients with diagnosed cancer.
- Cases of local use are observed in discoid lupus erythematosus, keloids, granuloma annulare.
Dexamethasone drops are used primarily in ophthalmology:
Allergic conjunctivitis of a non-purulent nature.- Keratitis, which causes inflammation of the cornea of the eye.
- Iritis, accompanied by an inflammatory process in the iris of the eye.
- Inflammatory processes that occur due to injuries to the eyeball or as a result of operations.
- Scleritis, characterized by inflammation in the deep layers of the eye sclera.
- Blepharitis, when the edges of the eyelids become inflamed, etc.
Contraindications
The mixture of drugs cannot be used if there is an individual intolerance to the active substances.
Contraindications are:
- pregnancy and lactation;
- impaired adrenal function;
- perforation of the eardrum (for use in the ear canal);
- taking monoamine oxidase inhibitors.
Inhalations are excluded in case of cardiovascular and respiratory failure, damage to the mucous membrane of the respiratory tract, bleeding from the lungs, pneumonia and a febrile state.
The drug is used with caution in case of renal failure.
A contraindication to the use of Dioxidin is the age limit of up to 18 years, therefore the possibility and necessity of using a mixture of drugs in children is assessed by the treating pediatrician.
Use of the drug
Ear drops with phenazone should be used strictly as prescribed by your doctor. Self-medication, no matter how effective it may seem, is fraught with complications. As usual, for a drug containing lidocaine and phenazone, instructions for use are included in the drug packaging.
Among the main recommendations is the need to warm the drops before use. Instill them into the external auditory canal when the patient lies with the sore ear up. Before instillation, it is necessary to check whether there is an allergy to lidocaine, and also, in order to avoid drops entering the bloodstream, be sure to ensure the integrity of the eardrum.
Usually only a few drops are instilled several times a day. The course of treatment lasts ten days, after which the doctor reviews further methods and the need for treatment.
The drug should not be used if the body is hypersensitive to it, individual intolerance, and is also not recommended for use in patients with suppressed bone marrow hematopoiesis.
If any new manifestations of the disease occur, in order to avoid complications with the patient’s health, it is necessary to immediately consult a doctor.
How to take Dioxidin and Dexamethasone
Complex drops are made individually according to the recipe. The attending physician determines the proportions of the active ingredients and dosage depending on the disease and age of the patient.
The prepared mixture is used for instillation into the nose or ears; in some cases, inhalation is carried out.
There are a large number of formulations for complex solutions. They may contain 3-4 components, and in some of them the number of ingredients can exceed 10. Together with Dioxidin and Dexamethasone, antihistamines, antiseptics, vasoconstrictors, sulfonamide antibiotics and the lincosamide group (Lincomycin, Sulfacyl) are used.
The prepared mixture is used for instillation into the ears.
It is recommended to use pharmaceutical products, because... When preparing at home, it is not possible to maintain the exact dosage of components. For example, from a 5 ml ampoule the required prescription amount may be 1, 2 or 3 ml.
For inhalation, drugs are diluted with saline solution. This method is used as prescribed by a doctor to treat cough, runny nose or sore throat, accompanied by swelling of the throat.
It is important to observe the storage conditions for complex solutions. They should be kept in the refrigerator.
For rhinitis
The mixture is instilled into each nasal passage according to the prescribed scheme. Before the procedure, it is necessary to rinse the nasal passages with a weak saline solution to remove mucus and purulent contents.
When prescribing the solution to children, it is recommended to use cotton swabs. They are soaked in medicine and placed in the nasal passages for several minutes.
In rare cases, dizziness is observed after the drugs.
How to use doses
It is better to take the drug as prescribed by your doctor after a detailed examination. In order not to cause harm to health, you should carefully read the instructions and carefully follow the rules of use and storage. For maximum effect, you need to use drops after cleaning the ear canal. The bottle of medicine needs to be held in your hands for some time to warm it up to body temperature. In order for the drops to be absorbed into the required area, it is advisable to pull the earlobe down, this will open the way to the middle ear and the drops will fall into the source of inflammation without being sprayed onto healthy areas
Minimum doses will not cause damage if used for no more than 10 days. On average, you need to drop three drops into the sore ear three times a day. After this, cover your ear with a cotton swab.
- During an exacerbation of the disease, you need to use the drug two drops every two hours. When the pain decreases, you can drip after four to six hours.
- If the form of otitis is mild, then two or three drops per day are enough.
- After instillation, you should lie on the opposite side and stay in this state for several minutes. This is done so that the drug is better absorbed.
- For greater effectiveness, dexamethasone is prescribed in combination with other medications.
- The duration of the course of treatment varies from two days to several weeks, it all depends on the patient’s health condition. If within three days the patient does not observe improvement, then you should contact an otolaryngologist to find out the causes of the pain.