Polydexa and rhinofluimucil at the same time

Which is better Vibrocil or Isofra?

Comparison of nasal preparations Vibrocil and Isofra
It is more appropriate to compare Isofra and Vibrocil by first analyzing the active components in the composition of the medicines.

Isofra is made on the basis of framycetin, which is a second generation aminoglycoside antibiotic. This group of bactericidal agents was first discovered in the 40s of the last century and found quite widespread use, as it turned out to be effective against microorganisms resistant to penicillin.

According to the manufacturer, framycetin has high antibacterial effectiveness when its optimal concentration is achieved. However, when using the drug topically, it is quite problematic to get close to it due to the low absorption capacity of the antibiotic in question.

The main negative point is the insufficient accumulation of framycetin at the site of infection, which leads to the emergence of resistant bacterial strains. On the other hand, with long-term use of the drug in high doses, its toxicity appears.

Today, doctors are inclined to conclude that the local use of antibacterial drugs is not sufficiently effective and, if possible, should be limited as much as possible.

"Vibrocil" - 15 ml bottle

Vibrocil is a complex topical preparation. The absence of a bactericidal component, which distinguishes Vibrocil from Isofra, is its advantage (given the non-infectious nature of the disease). Dimetindene and phenylephrine are used as its active substances, which complement and enhance each other’s therapeutic effects.

The substance dimethindene belongs to the group of second generation antihistamines. Its main advantages:

Phenylephrine is a vasoconstrictor, has a rapid effect on the mucous membrane, reduces swelling and the amount of mucus secreted. When applied topically, only a small fraction of the substance is absorbed into the blood, thereby minimizing side effects.

The negative aspects of using phenylephrine are as follows:

Differences between the analyzed drugs can be seen when considering their release forms. Pharmaceutical companies offer Isofra in the form of a nasal spray; and Vibrocil, in addition, is also in the form of nasal drops and gel.

The list of contraindications that distinguishes Isofra from Vibrocil is quite small and only includes sensitivity to bactericidal agents from the group of aminoglycosides. The drug is not recommended for use in children under one year of age, pregnant and lactating women, since no experimental tests have been conducted. Isofra is not used for rinsing the nasal sinuses due to the high probability of the emergence of resistant microorganisms.

On the contrary, Vibrocil in nasal drops is contraindicated:

Vibrocil spray and gel are contraindicated in children under 6 years of age. During pregnancy and lactation, the drug is not prescribed due to the possible negative effects of phenylephrine on blood vessels.

Isofra is produced by a French pharmaceutical factory and is in the same price category as Vibrocil, which is produced in Switzerland. However, the cost of drugs can vary significantly when sold in a particular pharmacy chain.

Question: Vibrocil or Isofra - which is better, it is reasonable to ask your doctor. Both drugs, along with positive properties, have a number of negative ones, which we discussed above. The appointment will be made based on the diagnosis and indications. If there is no improvement after a week of taking local medications, such as Vibrocil or Isofra, they should be discontinued in favor of other medications.

Polydexa for sinusitis: which is better for sinusitis with Phenylephrine or Rinofluimucil

268 10/22/2019 4 min.
Polydex spray is a pharmaceutical product for intranasal and local use for sinusitis.

The drug is a combination type that has a destructive effect on Gr+, Gr- strains of bacteria that cause inflammation of the nose and paranasal sinuses.

A full range of manifested therapeutic effects - vasoconstrictor, decongestant, antibacterial, antihistamine, antitoxic.

Is it possible to cure sinusitis with Polydex spray - how does the drug work?

Fights such manifestations of sinusitis as:

irritation of the mucous membrane caused by bacterial flora in the maxillary sinuses;
paroxysmal severe nasal congestion;
allergic, with constant redness, itching, sneezing;
swelling, hyperemia in the nasal cavity, cheeks, wings of the nose, under the eyes;
nasal breathing disorder.

Composition and active substance

The injection solution contains 4 active ingredients:

phenylephrine hydrochloride is a vasoconstrictor;
neomycin sulfate + polymyxin B – aminoglycoside antibiotics that destroy pathogens;
Dexamethasone sodium is an anti-inflammatory glucocorticoid, suppresses allergic reactions, stops the inflammatory process.

Auxiliary components:

lithium hydroxide+chloride;
antiseptic methylparaben;
macrogol;
polysorbate.

How and for what forms of illness to take

The combination of the main ingredients allows the spray to be used for the treatment and prevention of sinusitis of bacterial origin:

in acute, subacute forms;
complicated by allergic components;
during the period of exacerbation of the chronic form of the disease;
when a secondary infection occurs;
with serious nasal breathing disorders (vasomotor, allergic sinusitis).

How to use nasal drops with Polydex antibiotic - dosage for adults and detailed instructions

Before using the medicine, max clear the nose of mucus and adhered crusts; you can rinse the sinuses with a self-prepared or pharmaceutical saline solution. Adults can take 1 injection into each nostril 4-5 times per 24 hours, duration of treatment is 7-10 (max) days. The optimal dosage regimen to cure sinusitis is determined by an ENT specialist.

How to use? Injection rules according to the instructions for use:

Warm the bottle briefly in your hands and shake it slightly;
insert the tip evenly into the nostril, making sure that it is not pointed at the nasal septum;
the second nostril is pinched with a finger;
press on the bottle, inject the medicine and at the same time draw in air through the nose;
pull out the tip and inhale air through your nose 2-3 times (for better penetration of the drug);
Do not swallow; if it gets into your mouth, spit out.

Polydex with phenylephrine is not used to rinse the sinuses.

Contraindications and side effects

The spray is contraindicated for:

viral infections of the maxillary sinuses;
severe renal impairment (renal failure, albuminuria);
ischemic disease, severe coronary insufficiency;
high blood pressure;
all trimesters of pregnancy, during breastfeeding;
closed-angle forms of glaucoma;
concomitant use with antidepressants.

In case of individual intolerance to the components of the drug or if the dose or duration of treatment is exceeded, the following may occur:

acceleration of heart rate, tachycardia;
itching, urticaria;
drying of the nasal mucosa;
vomiting, nausea;
difficulty urinating;
dry mouth.

Advantages of treatment with the drug, will it help get rid of sinusitis, price

It is often prescribed by experienced otolaryngologists due to its following advantages:

highly effective, complex combinatorial composition, which allows you to get rid of almost all signs of sinusitis;
rapid relief of bacterial spread;
strengthens the blood-vascular walls of the nose and their tone;
restores the cellular composition of the mucosa;
prevents the development of various complications.

The cost of the spray is 297-320 rubles.

What to replace - analogues, their names and descriptions

An almost complete analogue of Polydex is Maxitrol eye drops. The drug has the same active ingredients (with the exception of phenylephrine) and can be used in the treatment of sinusitis.

The nasal drug Glenspray with azelastine has an effect similar to Polydex on the affected maxillary sinuses, will help relieve inflammation, and exhibits a prolonged antiallergic effect. Price – 470-518 rubles.

Which is better – Isofra or Polydex with phenylephrine, do the drugs help treat the disease

An ENT doctor must decide which of these 2 drugs is more effective for each specific case of damage to the maxillary sinuses. He will determine the causes of sinusitis, the nature of its course, take into account existing concomitant diseases, age and prescribe the best one. Their main, similar characteristics:

topical nasal antibiotics;
have an antibacterial effect with a bactericidal effect;
approved for the treatment of young children;
duration of treatment (not > 10 days);
approximately the same prices.

Features, differences:

Polydexa is a multicomponent composition of active substances that has vasoconstrictor, decongestant, and antihistamine effects. Helps with acute and chronic sinusitis, including those caused by exposure to various allergens. It has an extensive list of contraindications and can be used in children from 2.5 years of age.
Izofra – based on 1 component, with fewer contraindications. Treats acute inflammation in the nasal sinuses of non-allergic origin, is used as a prophylactic agent, and is approved for use in children from the age of 1 year.

Cost – about 400 rubles

How to use Rinofluimucil spray

Antibiotic nasal drug Rinofluimucil based on 2 active components: acetylcysteine - thins thick mucus, tuamingeptan - has a vasoconstrictor, decongestant effect. Suitable for the treatment of subacute, acute, vasomotor sinusitis with thick, mucopurulent discharge. Price (depending on the region) - 282-317 rubles.

Use of the drug Dioxidin

Antibacterial drug Dioxidin with a bactericidal effect, used for injections or nasal rinses in severe forms of purulent sinusitis, with severe inflammation and ulceration of the mucous membrane. Price: 280-381 rubles.

Due to the peculiarities of the toxicological effect, the drug is used with caution, after carrying out tolerance tests.

Effective analogue of Zinnat

The medicine Zinnat is based on a second generation antibiotic – cefuroxime, prolonged action. Belongs to the category of prodrugs, in which the pharmacologically active component is formed as a result of slow biotransformation of incoming substances in the body.

Suppresses growth, destroys Gr+, Gr- aerobic streptococcal, staphylococcal bacteria leading to acute forms of sinusitis. Available in powder form for the preparation of suspensions and tablets. Cost: tablets - 229-310 rubles, powder - 379-391 rubles.

The video shows a review of Polydex:

Conclusion

Polydex nasal spray is an effective remedy for the treatment of sinusitis caused by bacterial flora, aggravated by allergic components.
Polydexa is a rational therapy for acute processes in the maxillary sinuses.
The combined composition of the drug allows you to have a powerful complex effect, get rid of the disease in 10 days, and effectively use it during the period of exacerbation of chronic, allergic sinusitis, for the purpose of emergency care.
Suitable for use in pediatric practice.
We also recommend that you familiarize yourself with the drug Tsiprolet for sinusitis in this material.

Source: https://dokLOR.com/nos/oslozhneniya/gajmorit/lechenie-g/sprei-g/polideksa-primenenie.html

How often is Polydex replaced?

Most often, when considering analogues, doctors suggest replacing Polydex with Isofra spray. It has a different composition (only one substance - framycetin), but the price is practically the same. Therefore, isofra will not be suitable as a cheap remedy, but if the problem is intolerance to polydex, then isofra will be appropriate.

Diseases of the nasopharynx are often accompanied by a symptom such as “shooting ear.” It seems that there is no otitis media yet, but all the warning signs of its possible appearance are there. Polydexa wins in this case, because It can also be used for ear drops.

Isofra is a targeted antibacterial nasal drug; it is even called “an analogue of Polydex for the nose.” Isofra acts only on bacteria; it does not eliminate the accompanying symptoms.

Read more about which is better – isofra or polydex.

How to choose the right analogue?

Let's say that the patient is over 2.5 years old and was prescribed Polydex. After several doses of the drug, the patient complained of a burning sensation and severe swelling, which did not go away after 2–3 minutes. Subsequent injections also brought negative symptoms to the patient.

Here the doctor has to follow the following tactics.

Firstly, the analogue must be selected according to the permissible age of the patient, and also that the composition of the product must include an antibiotic, or, in extreme cases, an antiseptic.
It all depends on the clinical picture of the disease. If we are dealing with high body temperature, aggravated symptoms, and purulent discharge, then in this case only an antibiotic is needed, both locally and systemically.
If a bacterial runny nose is just beginning, when yellow or green snot appears, and the patient’s body temperature is normal, or does not exceed 37.2 degrees (in children under three years of age), you can try to treat the runny nose with antiseptic solutions, i.e. . Nasal drops (similar to Polydex) are suitable.
In any case, before starting treatment, the patient should be examined by an otolaryngologist to exclude the development of sinusitis, other sinusitis and otitis media. We are not even talking about self-medication with antibacterial agents.

It is advisable that before starting treatment, the doctor takes a microflora culture from the nasopharynx, then getting into the top ten will not be a problem, and the right remedy against a particular bacterium will surely be found.

The disadvantage of such diagnostics is the duration of bacterial culture, usually at least 5 days, and treatment cannot be delayed. Then drugs for bacterial rhinitis are prescribed at random. In most cases, such therapy brings results.

Polydexa - cheaper analogues, list with prices, comparison of effectiveness

Polydexa is a modern nasal antibacterial drug that appeared on the domestic market relatively recently, but has already established itself as a reliable remedy against bacteria.

The advantage of polydexa lies not only in the fight against pathogenic bacterial microflora, but also in the ability to have a vasoconstrictor, anti-edematous and anti-inflammatory effect.

This therapeutic complex is carried out thanks to the complex composition of the drug. It contains two antibiotics (neomycin and polymexin B sulfates), as well as agents that eliminate swelling and inflammation (phenylephrine hydrochloride and dexamethasone).

The drug is used after 2.5 years. It is widely used for infectious processes of the nasopharynx, especially in cases where signs of serious inflammation appear: pus, “green” in the snot, prolonged runny nose, pain in the projection of the maxillary sinuses, etc.

Polydexa is usually used up to three times a day, and the course of treatment lasts on average 5–7 days. More precise rules for the use of the drug are established by a pediatrician, ENT specialist or therapist. For the youngest patients, Polydex is indicated only once a day.

The price of Polydex (a 15 ml bottle made in France) is about 320 rubles. Not all patients may be satisfied with this cost, although Polydex cannot be called a super expensive product.

In such cases, cheaper analogues are selected, and Polydex is canceled.

It is also possible that the patient is allergic to some component of the composition, and one has to think about which alternative is better to choose.

How often is Polydex replaced?

Isofra is a targeted antibacterial nasal drug; it is even called “an analogue of Polydex for the nose.” Isofra acts only on bacteria; it does not eliminate the accompanying symptoms.

Read more about which is better – isofra or polydex.

How to choose the right analogue?

Here the doctor has to follow the following tactics.

Firstly, the analogue must be selected according to the permissible age of the patient, and also that the composition of the product must include an antibiotic, or, in extreme cases, an antiseptic.
It all depends on the clinical picture of the disease. If we are dealing with high body temperature, aggravated symptoms, and purulent discharge, then in this case only an antibiotic is needed, both locally and systemically.
If a bacterial runny nose is just beginning, when yellow or green snot appears, and the patient’s body temperature is normal, or does not exceed 37.2 degrees (in children under three years of age), you can try to treat the runny nose with antiseptic solutions, i.e. . Nasal drops (similar to Polydex) are suitable.
In any case, before starting treatment, the patient should be examined by an otolaryngologist to exclude the development of sinusitis, other sinusitis and otitis media. We are not even talking about self-medication with antibacterial agents.

Cheap analogues of Polydex - list with prices

Today, the following drugs can be offered as cheap analogues:

isofra (spray, 15 ml) – 300 rubles (slightly cheaper);
Okomistin (eye drops, 10 ml) – 150 rubles;
sialor (drops, 10 ml) – 260–290 rubles;
miramistin (solution, 50 ml) – 240–260 rubles;
collargol (drops) – 150 rubles;
chlorophyllipt (oil solution, 20 ml) – 150 rubles.

Comparative characteristics of Polydexa with other nasal agents

When choosing one of the medicines, it is necessary to compare the drugs, according to official instructions. The main thing is the composition and pharmacological action, i.e. we need to find either a structural analogue or a substitute drug with a similar therapeutic effect.

Plus, taking into account the wishes of the workers, we will have to find an analogue at a more reasonable price, because Not all of our citizens can buy drugs at average and high prices. Let's compare several drugs with Polydexa and determine whether it can act as its analogues.

Rinofluimucil or Polydexa?

The drugs are produced in different countries. Polidexa is produced in France, and rinofluimucil in Italy. They are completely different in their composition, therefore, their pharmacological effects are different. The active components of rinofluimucil are tuaminoheptane sulfate and acetylcysteine.

The main task of Polydexa is to destroy bacteria (antibacterial effect), and Rinofluimucil is to eliminate swelling and thin out thickened mucus.

Therefore, rhinofluimucil cannot be called an analogue. Despite this, both drugs have similar indications for use. These are mainly various sinusitis and rhinitis. Contraindications are also largely the same. Rinofluimucil is not yet recommended for thyrotoxicosis (endocrine pathology).
Unlike Polydexa, rhinofluimucil is allowed to be used in pediatrics from the age of one. This makes it possible to alleviate the symptoms of rhinitis from early childhood, when many medications are still contraindicated.

Due to the fact that rinofluimucil does not contain antibacterial components, it is less toxic . Polydexa contains two antibacterial substances. Many patients do not want to use this medicine for precisely this reason, despite the fact that it is used locally and does not carry a large toxic load.

In terms of price, the drugs do not have any special differences. Rinofluimucil 10 ml (nasal spray) costs an average of 280 rubles, which is 40 rubles cheaper than polydex.

We recommend - instructions for use of Rinofluimucil.

Nasonex or Polydex?

First of all, let's start with the composition of these drugs. They are completely different, which means that we are no longer talking about structural identity. Polydexa is a complex drug that destroys bacteria in the nasopharynx or middle ear. Those. its main task is to neutralize bacteria. The drug contains four active ingredients, two of which are antibiotics.

Nasonex is a mono drug, the active ingredient is mometasone fuorate. This substance is a glucocorticosteroid. Polydex also contains a substance of this group - dexamethasone. This is the only similarity between these drugs in composition.

Nasonex exhibits an anti-inflammatory and antihistamine effect, but it cannot destroy the bacterial flora, because There are no antibacterial components in the composition. Nasonex is recommended for use only from the age of two.
Another advantage of Nasonex is its ability to activate neutrophils, which begin to block bacteria in the focal area. Thanks to this, titers of pathogenic flora do not increase, but are not destroyed.

Therefore, only the doctor makes the choice in favor of one of the remedies, and it is up to him to decide what will be best for a particular patient.

Nasonex (50 mcg/dose, 1 piece) is more expensive than Polydex, its price is about 440 rubles.

Important! Nasonex and Polydexa are used in short courses, sometimes they are even combined. Patients should be aware that the medications in question are not used for ordinary and uncomplicated runny nose.

Nasonex: instructions and analogues.

Protargol or Polydexa – which is better?

The drugs are not structural analogues. The active ingredient of protargol is silver proteinate (essentially a protein complex). This substance has a short shelf life. In the post-Soviet space, it was always prepared in special prescription departments according to a doctor’s prescription. Today, Protargol has an analogue - Sialor, produced by a Russian pharmaceutical company.

It should be noted that silver proteinate exhibits antiseptic and antibacterial properties, although this drug is not classified as an antibiotic. The drug also has an anti-inflammatory and drying effect, constricts blood vessels and relieves swelling of the nasopharynx.

It follows that theoretically, and as practice proves, with the help of protargol you can cope with bacteria and eliminate other symptoms of rhinitis. Usually, with an uncomplicated bacterial runny nose, even when there is “green” in the snot, doctors recommend treatment without antibacterial agents. If the effect does not occur after a few days, then a local antibiotic is prescribed.

Therefore, in terms of therapeutic action, Protargol and Polydex are the same, therefore, they are conditional analogues.

Sialor (protargol) Renewal kit for preparing a solution of 2% 10 ml with a spray costs about 290 rubles. If you order protargol at a pharmacy, it will be cheaper, about 100–150 rubles. It follows that protargol in any form is cheaper than polydex.

Instructions for use of Protorgol drops.

Polydexa or Vibrocil?

The drugs have different pharmacological effects. Vibrocil contains the following substances: dimethindene maleate and phenylephrine. The first substance relieves the chain of allergic reactions, the second fights swelling and inflammation, i.e. in total we get anti-allergic, anti-edematous and anti-inflammatory effects.

Vibrocil can be purchased in the form of a spray, drops and gel. The drug is used for various types of rhinitis that do not have bacterial microflora. These could be allergic and viral rhinitis, chronic sinusitis, otitis media (in this case, Vibrocil eliminates the symptoms).

Vibrocil is approved for use in children under one year of age. Clinical trials have shown the safety of using this drug in this age group.
Unlike Polydexa, Vibrocil cannot treat bacterial rhinitis, so it cannot be called an analogue. To replace polydex, ideally, only drugs that contain antibacterial components are selected.

Vibrocil is cheaper than Polydex. The price for nasal drops (15 ml) is approximately 290 rubles. Despite the fact that the drug is cheaper, it cannot be used as an analogue, therefore, in principle, there is no need to compare these products, they are different.

Instructions for use of Vibrocil.

Polydexa or Sofradex?

Sofradex is an analogue of Polydex, although their composition is different, but the principle of action is largely similar. Both drugs have antibacterial substances and glucocorticosteroids.

In Sofradex, gramicidin and framycetin sulfate act as antibacterial agents, and the glucocorticosteroid is dexamethasone. As you can see, Polydex and Sofradex are quite strong drugs that contain two antibacterial agents.

Unlike polydex, sofradex is also used in ophthalmic practice. The main purpose of Sofradex is the treatment of bacterial and inflammatory diseases of the eyes and ears.

Instructions for use of Sofradex for ears.

The instructions for the drug do not contain instructions for using Sofradex for rhinitis. Despite this, this drug is widely used to treat bacterial rhinitis in adults and children.

When making a choice towards one of the drugs - Polydex or Sofradex, first of all, you need to proceed from the sensitivity of bacteria to the antibiotics that are part of these drugs. The choice of drug is made by the doctor, and the doctor’s experience will always tell you which drug will be more effective for a given clinical picture.

The price for Sofradex (eye and ear drops, 5 ml) is 330 rubles. Conclusion: the price of Polydex and Sofradex is at the same level.

Comparative characteristics of Polydexa with other nasal agents

Rinofluimucil or Polydexa?

The main task of Polydexa is to destroy bacteria (antibacterial effect), and Rinofluimucil is to eliminate swelling and thin out thickened mucus.

Therefore, rhinofluimucil cannot be called an analogue. Despite this, both drugs have similar indications for use. These are mainly various sinusitis and rhinitis. Contraindications are also largely the same. Rinofluimucil is not yet recommended for thyrotoxicosis (endocrine pathology).
Unlike Polydexa, rhinofluimucil is allowed to be used in pediatrics from the age of one. This makes it possible to alleviate the symptoms of rhinitis from early childhood, when many medications are still contraindicated.

In terms of price, the drugs do not have any special differences. Rinofluimucil 10 ml (nasal spray) costs an average of 280 rubles, which is 40 rubles cheaper than polydex.

We recommend - instructions for use of Rinofluimucil.

Polydexa and rhinofluimucil at the same time

Both medications effectively and efficiently fight sinus diseases; they should not be used during pregnancy or in children under three years of age. The drugs are contraindicated in case of hypersensitivity to any of the components and can cause an allergic reaction if abused.

The drugs are indicated for any form of rhinitis or sinusitis of various etiologies. They have the same instructions for use for both children and adults.

Rinofluimucil or Polydexa, which is better for children?

It is impossible to answer this question, since these drugs, although prescribed in the treatment of rhinitis (runny nose), have different effects. When choosing a drug for the treatment of inflammatory processes in the nasal and auditory cavities, you should first determine the nature of the disease.

For sinusitis caused by a bacterial infection, it is worth using Polydexa, since this medicine contains antibiotics that destroy the cause of the disease.

For rhinitis uncomplicated by a viral or bacterial infection, it is worth prescribing Rinofluimicil, as its active ingredients will relieve swelling and accelerate the flow of mucus from the nose.

Also, in severe forms of sinusitis, which is caused by a bacterial infection, Polydexa and Rinofluimil can be used together. When taken simultaneously, the components of Rinofluimicil will eliminate the symptoms of the disease - swelling of the mucous membrane and sputum discharge, and the Polydex antibiotics will destroy the pathogenic microorganisms that caused the disease.

When choosing an effective drug for the treatment of rhinitis, sinusitis and other nasal diseases, it is also worth determining the nature of the disease.

In case of bacterial sinusitis, sinusitis, or otitis, without damage to the eardrum, it is worth prescribing Polydex.

For rhinitis, sinusitis, uncomplicated by viral and bacterial infection, Rinofluimucil would be an appropriate drug.

Description of drugs

Polydexa is a combined medicinal substance for the treatment of otitis (inflammation of the middle and outer ear).

Rinofluimicil is a medicinal substance that has anti-edematous, anti-inflammatory and vasoconstrictor effects. Used in the treatment of rhinitis (runny nose).

Compound

Polydexa - the active ingredients are: dexamethasone (glucocorticoid) and antibiotics (neomycin sulfate and polymyxin B sulfate).
The drug also contains additional substances to give it a pharmacological form.
Rinofluimicil - the active ingredients of this substance are: acetylcysteine and tuaminoheptane sulfate.
The drug also contains additional pharmacological agents to give shape.

Mechanism of action

Polydexa - thanks to the combination of a glucocorticoid (dexamethasone), which has an anti-inflammatory effect, as well as antibiotics that affect gram-positive and gram-negative strains of microorganisms, the drug fights most infectious diseases of the ear canals.
Rinofluimicil - acetylcysteine, present in this medicinal substance, thins mucus and phlegm in the nasal cavity. Tuaminoheptane, thanks to its anti-edema and vasoconstrictor effect, restores the patency of the nasal passages.

Indications

Inflammation of the external auditory canal, without perforation (damage) of the eardrum;
Bacterial lesions of the nasal cavity (sinusitis).

Various forms of rhinitis (runny nose) (chronic, acute, subacute, vasomotor), with problematic sputum discharge (mucopurulent).

Contraindications

Individual intolerance to the components of the drug;
Trauma and perforation of the eardrum;
Viral or fungal infections of the ear canal;
Pregnancy and lactation period.

Individual intolerance to the components of the drug;
Angle-closure glaucoma (impossibility of outflow of tear fluid through the closed anterior chamber of the eye, leading to increased intraocular pressure);
Thyrotoxicosis (enlargement of the thyroid gland and excess thyroid hormones);
Taking antidepressants.

Side effects

Local allergic reactions (skin redness, itching);
If the integrity of the eardrum is damaged, it may have a negative effect on the internal structures of the hearing aid.

Allergic reactions to the components of the drug;
Psychomotor agitation;
Increased heart rate and strength;
Increased blood pressure;
Problems with urination (urinary retention);
Inflammatory processes in the sebaceous glands of the nose.

Release form, price

Spray (with phenylephrine), 15ml, 1fl, - “from 331r”;
Ear drops, 10.5 ml, 1 fl., “from 233 rub.”

Nasal spray, 10ml, 1fl, - “from 269 rub.”

Nasonex or Polydex?

Nasonex exhibits an anti-inflammatory and antihistamine effect, but it cannot destroy the bacterial flora, because There are no antibacterial components in the composition. Nasonex is recommended for use only from the age of two.
Another advantage of Nasonex is its ability to activate neutrophils, which begin to block bacteria in the focal area. Thanks to this, titers of pathogenic flora do not increase, but are not destroyed.

Therefore, only the doctor makes the choice in favor of one of the remedies, and it is up to him to decide what will be best for a particular patient.

Nasonex (50 mcg/dose, 1 piece) is more expensive than Polydex, its price is about 440 rubles.

Nasonex: instructions and analogues.

Protargol or Polydexa – which is better?

Therefore, in terms of therapeutic action, Protargol and Polydex are the same, therefore, they are conditional analogues.

Instructions for use of Protorgol drops.

Sinupret or Rinofluimucil - which is better?

Those who are looking for a generic Rinofluimucil with a minimum number of side effects should pay attention to the combination drug Sinupret. The medicine is distinguished by its herbal composition, which includes the following natural ingredients:

elderberry inflorescences;
verbena herb extract;
sorrel leaf;
primrose inflorescence extract;
Forge gentian extract.

Sinupret has antiviral, moderate antibacterial, anti-edematous, anti-inflammatory, secretomotor and secretolytic effects. Accelerates the outflow of exudate from the upper respiratory system and paranasal sinuses. Indicated for chronic and acute sinusitis, accompanied by viscous secretions. Contraindicated in the treatment of children under 2 years of age, epilepsy and liver diseases, as well as during pregnancy, since it contains the auxiliary component ethanol. Sold in a pharmacy, does not require a prescription.

Table - existing forms of the drug Sinupret with prices *

Name	Manufacturer	Active substance	Price
SINUPRET 100ML DROPS	Bionorica SE	*	RUB 355.10
SINUPRET N50 TABLE P/O	Rottendorf Pharma GmbH/Bionorica SE	*	RUR 349.70
SINUPRET N50 DRAGEE	Rottendorf Pharma GmbH/Bionorica SE	*	Not available

Polydexa or Vibrocil?

Vibrocil is approved for use in children under one year of age. Clinical trials have shown the safety of using this drug in this age group.
Unlike Polydexa, Vibrocil cannot treat bacterial rhinitis, so it cannot be called an analogue. To replace polydex, ideally, only drugs that contain antibacterial components are selected.

Instructions for use of Vibrocil.

Vibrocil and its analogues

Successful treatment of a runny nose depends on various reasons, but first of all, on determining its etiology and the correct selection of medications. Each drug has a different composition and, accordingly, has a different effect on the nasal passages. Therefore, only a doctor should choose nasal remedies Nazivin, Vibrocil or Protargol, and determine which will help better and faster.

Features of Vibrocil

The nasal drug is produced by the Swiss company Novartis Consumer Health and belongs to the group of combined drugs. Its action is determined by two active components - phenylephrine and dimethindene.

The first substance affects the alpha receptors of the mucous membrane, causes their narrowing, blood outflow and, due to this, eliminates swelling and increases the lumen in the nasal passages.

After instillation, it has an immediate effect, the effect lasts for a long time - 6-8 hours. When using any nasal products containing it, you must remember that phenylephrine constricts blood vessels not only in the nasal part, but throughout the body.

For this reason, Vibrocil should not be used during pregnancy.

Dimetindene is an antihistamine, that is, it blocks the production of histamine and thereby neutralizes the allergic cause of a runny nose. Its advantage is that it belongs to the 2nd generation substances - it does not cause drowsiness, changes in behavior or psycho-emotional state. In addition, dimethindene does not dry out the mucous membrane and acts quickly and for a long time.

The drug is available in several pharmaceutical forms, designed for use from different ages: drops are used from 12 months, gel and spray - from 6 years.

Vibrocil is designed to eliminate various types of rhinitis, including allergic rhinitis. It can be used to treat the nose before operations and to relieve swelling after them.

Vibrocil should not be used in case of intolerance to the components, a runny nose with purulent discharge, together with MAOIs, during pregnancy and pregnancy. When using it, there is a burning and tingling sensation at the application site. The drug is addictive and addictive if used for long periods of time. An overdose can provoke cardiac dysfunction, increased agitation, and increased blood pressure.

Sialor (Protargol)

Sialor is produced by domestic pharmaceutical enterprises “Obnovlenie” and “Echo”. Protargol is prepared in the prescription departments of pharmacies that manufacture medications. Available with different contents of active substance.

The effect of nasal agents is determined by its main component - silver proteinate (protargol). The substance has antibacterial properties, affecting inflammatory pathogens: streptococci, staphylococci and other pathogenic microorganisms. In this case, the substance acts selectively, without affecting the beneficial flora.

Protargol is a protein compound that ensures the normal condition and functioning of cells. It has antiseptic, astringent and anti-inflammatory effects.

The drugs are prescribed in the presence of adenoids, various rhinitis, otitis media, chronic diseases of the nasal cavity with concomitant dryness of the mucous membrane.

They can also be used as a preventive measure during seasonal epidemics, living or working in unfavorable conditions, washing wounds in the nasal area, in preparation for and after operations, as a hygienic product. The drugs are approved for use in treatment from infancy.

The result of using Sialor is different than that of Vibrocil: it eliminates the development of the cause of the runny nose - inflammation. And the last drug relieves swelling in the nasal passages and neutralizes the effect of allergens.

Nazivin

The popular drug is produced by the German company MERCK. The nasal remedy belongs to the group of adrenergic agonists, since the main substance oxymetazoline causes vasoconstriction by acting on alpha-adrenergic receptors of the mucous membrane.

The drug is available in the form of drops and sprays with different contents of the active substance, which allows you to eliminate a runny nose even in newborns and infants.

Like all adrenergic agonists, oxymetazoline acts quickly - it constricts blood vessels a few minutes after administration, the effect lasts for 10-12 hours. Nazivin is used for acute respiratory diseases with concomitant rhinitis, as well as allergic and vasomotor rhinitis. It is used to eliminate swelling during diagnostic procedures.

Protargol and Nazivin, although used for runny nose and nasal congestion, perform different tasks: The first suppresses the development of infection, it can be used as an antiseptic or hygienic agent. Naphthyzin only eliminates swelling, providing better air passage, but does not affect the cause of the disease.

Therefore, they are often prescribed together: first, Nazivin is dripped to relieve swelling and the nose begins to breathe, and after it takes effect (after 10 minutes), Protargol is administered as a disinfectant and antimicrobial agent. Usually such manipulations are done three times a day.

In order for the nose to start working properly, various drugs are used. A large selection of nasal remedies allows you to select the most effective remedies and effectively fight the runny nose.

Source: https://lekhar.ru/lekarstva/lor-sredstva/vibrocil-i-ego-analogi/

Polydexa or Sofradex?

Sofradex is an analogue of Polydex, although their composition is different, but the principle of action is largely similar. Both drugs have antibacterial substances and glucocorticosteroids.

Unlike polydex, sofradex is also used in ophthalmic practice. The main purpose of Sofradex is the treatment of bacterial and inflammatory diseases of the eyes and ears.

Instructions for use of Sofradex for ears.

The instructions for the drug do not contain instructions for using Sofradex for rhinitis. Despite this, this drug is widely used to treat bacterial rhinitis in adults and children.

The price for Sofradex (eye and ear drops, 5 ml) is 330 rubles. Conclusion: the price of Polydex and Sofradex is at the same level.

Polydexa

Category: antibacterial and anti-inflammatory agent.
Active ingredients: neomycin, polymyxin B, dexamethasone.

Action and effectiveness: helps reduce and quickly eliminate inflammation, suppresses the development of pathogenic bacteria during bacterial rhinitis. It is not a remedy for the common cold, but is sometimes prescribed for bacterial rhinitis at the discretion of the doctor.

Dosage forms: drops.

Indications: bacterial rhinitis, green or yellow snot with pus.

Contraindications: pregnancy, lactation, damage to the eardrum. Useless for any type of runny nose in which there is no thick purulent snot (including contraindicated for ARVI).

The child has green, thickening snot - this is where products like Polydex will be useful

Reviews
“I have the same situation as Yulia - the runny nose itself seems to be tolerable, I feel fine, but after three or four days lumps appear in the throat, the snot turns green, and that’s it, goodbye breathing. The doctors found out it was a microbial infection. At first, Isofra was dripped, then I tried Miramistin. But Polydex’s cold drops helped the most. With them, a runny nose goes away as quickly as with Miramistin drops, in two days, but during treatment the swelling subsides and you can breathe. And with Miramistin, the nose is stuffy until all the bacteria die. I talked to other girls, they say that Isofra works for them the same way as Polydex works for me. Only, probably, my bacteria themselves are resistant to Isofra.”
Irina, Samara
“I can’t say unequivocally that Polydex drops are great. If you just have a runny nose with clear clear snot and even a fever, Polydexa only clears your nose a little. But the same Naphthyzin cleans it much better. But when the snot definitely turns green, the runny nose itself goes away after 2-3 days. And whether you drip Polydex here or not, it won’t particularly speed up this action. Maybe someone who has a runny nose that lasts for a long time notices the effect, but I have no problems with it. As a result: I bought Polydex, applied it twice during the winter, and forgot about it.”
Irina, St. Petersburg

Dioxidine or polydex – what to choose?

1 ml of dioxidine contains 5 or 10 mg of hydroxymethylquinoxyline dioxide. The drug does not belong to the structural analogues of polydexa, but is a potent antibacterial agent. Therefore, it can be considered as an analogue in terms of therapeutic action. Polydexa is a complex drug, dioxidin is a mono drug.

The antibacterial effect of dioxidine solution is stronger, so it is used not only in otolaryngology, but also in other medical fields. It is effective in treating septic wounds when other antibiotics have failed. The conclusion suggests itself: this remedy is used only for complicated forms of the disease.

In ENT practice, dioxidin is recommended for tonsillitis, otitis, and all types of infectious sinusitis.

Dioxidin is very aggressive, so if the doctor prescribed it for treatment, try to clarify how far the inflammatory process has gone . Unfortunately, in order to show a quick effect, some doctors with dubious professionalism use dioxidin in “battle” where it is not needed. Patients should understand that potent drugs are a reserve for the most severe infections.

Dioxidin (5 mg/ml solution, 5 ml ampoule No. 10) costs about 390 rubles.

Conclusion: if polydex and other antibiotics do not work, dioxidin is indicated.

Article on the topic - instructions for using Dioxidin for the treatment of the nose.

Conclusion

After reading the article, it is not difficult to conclude that all antibacterial drugs are serious medicines. Only a doctor can determine the correct prescription of a particular medication. For example, they prescribed a local antibiotic for the nose, but it didn’t work, it needs to be changed. How to determine analogue? It is difficult to do this on your own, without medical knowledge.

We should also not forget that antibiotics not only eliminate bacterial flora, but also have a toxic effect on beneficial bacteria. Therefore, therapy with Polydexa and its analogues should be under strict medical supervision, especially if the treatment concerns children. Be healthy!

Source: LOR-explorer.com

Adrianol or Rinofluimucil - which is better?

The drug has a vasoconstrictor effect. It is one of the anticongestive vasoconstrictors, alpha-adrinomimetics. Prescribed for acute and chronic sinusitis, and also as an auxiliary decongestant.

In ENT practice it is widely used as an antioxidant, analgesic and a remedy that effectively resists pathogenic bacteria. The advantage of Adrianol over many other analogues is the absence of odor and color. Contraindications for use:

the presence of arterial hypertension or severe kidney damage;
thyrotoxicosis;
IHD and glaucoma.

Since large-scale studies have not been conducted on the effect of the drug on the female body during pregnancy and lactation, its use is prohibited. The advantage of the drug is its low cost compared to analogues. Available without a prescription.

Table - existing forms of the drug Adrianol with prices *

Name	Manufacturer	Active substance	Price
ADRIANOL 10ML NAZ DROPS FOR ADULTS	Hello HFZ JSC-Leskovac	Tramazolin	130.70 RUR
ADRIANOL 10ML NAZ DROPS FOR CHILDREN	Hello HFZ JSC-Leskovac	Phenylephrine	131.20 RUR

What does the medicine consist of, in what form is it produced?

Pharmaceutical companies produce the drug in 3 types: drops, nasal spray and gel. This is a combined medication that contains two active components. The first substance is phenylephrine (2.5 mg), the second is dimethindene maleate (250 mcg per 1 ml or gram). The product (in all forms) contains the following additional components:

anhydrous disodium phosphate (4.4 mg);
hexahydric alcohol with a sweetish taste (35 mg);
purified water (up to 1 ml);
citric acid monohydrate (2.6 mg);
lavender flower extract deterpene (0.2 mg);
benzalkonium chloride (0.1 mg).

The medicine, available in the form of a spray, contains methylhydroxypropylcellulose.

Attention! Thanks to the presence of lavender oil, the medicine is well tolerated by small children.

How much does the drug cost in Russian pharmacies? The price of the medicine ranges from 269 to 385 rubles. Of all the types of Vibrocil, the most expensive medicine is in the form of a spray.

What is the effect of the drug?

Vibrocil for children refers to medications that are used for the therapeutic treatment of the bronchi and lungs during colds. Is it vasoconstrictor or not?

All forms of the medicine are aimed at preventing the development of an allergic reaction, and increase the tone of the vascular wall of the nose, due to which the lumen of the blood vessels decreases.

Phenylephrine is an active ingredient that causes constriction of blood vessels. Dimetindene maleate is a synthetic antihistamine that has an antipruritic effect. It is an H1 receptor blocker.

For what conditions is it used?

Let's look at what the medicine helps with. The choice of drug form depends on the course of the disease and the age of the patient. In accordance with the annotation (instructions for use), the medicine is used for the following conditions:

inflammatory local changes in the nasal mucosa;
dysregulation of vascular functioning;
chronic inflammation of the nasal mucosa;
inflammatory disease of the paranasal sinuses;
from a runny nose caused by allergies;
inflammation localized in the tissues of the tympanic cavity, auditory tube and mastoid process.

The medication is used in preparation for surgery. Often the medicine is used for sinusitis. Due to the simultaneous vasoconstrictor and antihistamine action of Vibrocil, it is effective for adenoids in children.

How to take Vibrocil in various forms of release

Before using the medicine, it is necessary to clear the child’s nose of excess mucus and crusts. You can use a store-bought saline solution, such as No-salt or Aquamaris. After rinsing your child's nose, ask him to blow his nose. For young children, fluid is removed from the nose using a special syringe with a soft tip or an aspirator.

Application of drops

At what age can the product be used? Nasal drops are often prescribed from birth, although many doctors do not recommend the use of Vibrocil for children under one year of age. Vibrocil drops - instructions for use:

From the moment the baby is born until the first year of life, the number of drops used in each sinus is one. Frequency of application per day 4 times.
From 12 months to six years of age, doctors recommend using 2 drops in each nasal passage 4 times a day.
At school age, from the beginning of the seventh year of a child’s life until the age of 12, the number of drops in each nostril is three. Apply Vibrocil up to 5 times a day.
Adolescents and adults are prescribed 4 drops 5 times a day.

Vibrocil for infants is used for 7 days. The course of therapy with the drug for children aged 7 years and older lasts 10 days. After the specified period has expired, use of the drug must be stopped.

How to use the gel

The nasal gel should not be used for more than one week. If there is no positive effect, you should consult a doctor and replace the drug with an analogue. Vibrocil gel - instructions for use: after cleaning the nasal passage, squeeze out a small amount of the product - about the size of a pea - onto a cotton swab. Place a cotton swab in your nose and lubricate it as deeply as possible.

Using nasal gel right before bed will ensure a calm and healthy rest. Nasal congestion will not bother you throughout the night.

Spray application

How to take Vibrocil as a spray? Children who are six years old are given 2 injections into each nasal passage 4 times a day. Adults and adolescents over 12 years of age are also prescribed several injections.

When using the spray, hold the bottle of medicine vertically, placing the tip in the nose. The course of treatment is 7 days (week).

Fenistil

Category: antiallergic agent.
Active ingredients: dimethindene.

Action and effectiveness: interrupts or inhibits the allergic reaction.

Dosage forms: drops, emulsion, gel.

Indications: allergic and vasomotor rhinitis.

Contraindications: pregnancy and lactation, children under 1 month of age (for children under 6 years of age, use under medical supervision). Useless for ARVI and bacterial rhinitis.

It will not be possible to treat an allergic rhinitis with drops - Fenistil will only alleviate the patient’s condition for a few days

Reviews
“My allergy to poplar fluff began six years ago, and now I constantly fall out of normal life for a month a year. Of course, I tried almost all the drops for a runny nose until I talked to the doctor. There are several remedies for allergic rhinitis that can help you feel normal. These are Nazaval, Pinosol, Vibrocil, Fenistil, all sprays or drops for a runny nose. I liked Nazaval and Fenistil the most. Nazaval is generally harmless, but it is difficult to use. If there is mucus in the nose, or one sneezes frequently, it will quickly fly out and its effect will end. But Fenistil works well.”
Lena, Kyiv
“I believe that the best drops for a runny nose in the summer are Fenistil. I once used its gel for grass allergies, but now the drops help with ragweed flowering. Even if the snot is already flowing and your eyes are watering, you blow your nose, go into the room, bury it and sit for an hour. Then you can safely go outside - there will be no reaction for several hours. With my work schedule, it’s enough for me to instill twice a day and make sure that the air conditioner in the room works with a filter. And that’s it, I feel good.”
Yulia, Rostov-on-Don

In what cases should it not be used, side effect?

The drug is almost always well tolerated. Like any medication, Vibrocil has some contraindications, which prevent the patient from taking this drug:

hypotrophy of the nasal mucosa;
offensive runny nose with atrophy;
sensitivity to components.

You cannot take the medicine together with MAO inhibitors. Use the drug with extreme caution for heart and vascular diseases.

Attention! Vibrocil gels and sprays should not be given to children under six years of age.

The medicine in any form is contraindicated during pregnancy and lactation. After the initial instillation, itching, dryness and a slight burning sensation appear. All symptoms go away quickly. But, if the allergic reaction does not go away even after using activated carbon, the drug must be replaced. In such situations, doctors prescribe analogues of Vibrocil. For example, Polydexa, Albucid and other medications suitable in composition and action.

Side effects may include headache, impaired sense of smell, and conjunctivitis. Accidental ingestion of the medicine threatens the child with fatigue, stomach pain, insomnia, and tachycardia. If a child drinks the product, it is necessary to rinse the stomach. For children under one year old, an ambulance is called.

About the drug

Rinofluimucil is a complex anticongestive drug intended for the treatment of local inflammatory processes. It has a mucolytic effect, promotes the breakdown of intramolecular and intermolecular disulfide bonds of mucopolysaccharide secretions, reducing viscosity. Prescribed for subacute and acute rhinitis with mucopurulent thick secretion, vasomotor and chronic rhinitis. Thanks to the combination of acetylcysteine with tuaminoheptane, a pronounced vasoconstrictor effect is achieved. Prescribed in case of:

sinusitis;
chronic and vasomotor rhinitis;
acute and subacute rhinitis, accompanied by mucopurulent secretion.

The drug is contraindicated in hypertension, thyrotoxicosis, glaucoma and hyperfunction of the thyroid gland. It is strongly not recommended to use the aerosol in parallel with taking antidepressants. In case of individual intolerance, it is necessary to replace Rinofluimucil with another drug. Before taking the drug, you should consult with your doctor and familiarize yourself with the basic rules for using the spray.

1 click on the cap equals one dose.
For adults, double dosage is prescribed.
The number of inhalations should not exceed 3-4 times a day
The duration of the therapeutic course should not exceed 7 days.

Side effects may include urinary disorders, high blood pressure, rapid pulse, rashes and itching of the skin. The drug is prescribed with great caution for the treatment of children under 3 years of age. Use during pregnancy and lactation is strongly not recommended, and is allowed in some cases according to the doctor’s decision. Available without a prescription.