What it is?
At its core, it is a non-steroidal anti-inflammatory drug with various properties.
The drug is used as:
- Anesthetic.
- Antipyretic.
- Anti-inflammatory agent.
Nominally, the medication is classified as an NSAID; its active component is ketoprofen.
In addition to this substance, the composition also includes other components, but the components depend on the form of release of the drug.
Release form
In the pharmacy chain you can find the medicine in several forms of release; the drug is sold:
- in the form of rectal suppositories;
- in powder form, in the form of granules used to prepare a solution, it is used internally;
- in the form of a solution intended for local use.
Attention! The drug can be used in any convenient form; it is prescribed based on the indications for use and patient preferences.
The doctor independently selects the medicine; As for the shape, this choice is made by the patient, based on individual preferences and ease of use.
pharmachologic effect
The medication has a number of actions and is used for the following purposes:
- Reduce the severity of pain.
- Stop the inflammatory process at the initial stage of development.
- Reduce body temperature, but in case of fever it may be ineffective for objective reasons.
A solution, spray or powder - not only has an anesthetic effect - the drug in any form of release has a bactericidal effect, preventing the growth and reproduction of pathogenic microorganisms. But, in terms of effectiveness, it cannot be compared with antibiotics or other drugs with antibacterial activity.
How does it affect the human body:
- disrupts the synthesis of polysaccharides;
- suppresses the production of leukotrienes;
- has antibactericidal activity;
- delays the release of enzymes from membranes;
- directly and indirectly affects pain receptors.
OCI is characterized by a direct effect on pain receptors, due to which the severity of the reaction is sharply reduced.
Indications and contraindications
Nominally, the drug in any form does not have many contraindications; it is not recommended to use it if you have:
- Hypersensitivity or individual intolerance to drug components.
- Allergies to substances included in the drug in any of its forms.
- The period of pregnancy in women, especially in the first and third trimester.
- Lactation period, provided that the woman continues to feed the baby with breast milk.
- Children's age (considered a relative contraindication, since use as prescribed by a doctor is acceptable).
Children's age, pregnancy and lactation - at this time the medication is prescribed on the basis of potential harm and possible benefit. If, in the opinion of the doctor, the medication will bring more benefit to the patient than harm, then its use is considered acceptable. Otherwise, refuse to use the medicine.
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The following conditions may serve as indications:
- diseases of the musculoskeletal system, inflammatory and infectious origin (arthritis, inflammatory processes in tissues after traumatic injuries);
- pain syndrome of various origins, to relieve unpleasant symptoms;
- the drug is widely used in ENT practice, helps reduce the severity of pain in sore throat, laryngitis and other diseases of various etiologies;
- as an analgesic aid during certain surgical procedures.
Since the drug helps relieve pain, it is actively used in the postoperative period. It is permissible to carry out complex therapy, that is, the use of several painkillers at the same time.
OCI will also help you get rid of:
- For pain in joints and muscle tissue.
- For premenstrual cramps in women.
- For severe headaches, but not used in the treatment of migraines, only as part of combination therapy.
Information: the medication is most rarely used as an antipyretic; its use must be agreed with the doctor. It is acceptable to use OKI if other drugs with similar effects are ineffective.
Mode of application
The drug OKI is available in the form of a spray, so you need to prepare a solution for rinsing from it. To begin with, remove the measuring cup from the cardboard box, which is necessary for preparing the solution, and prepare well-warm water, the temperature of which does not exceed 40 degrees.
Features of the use of the drug for the treatment of adults
Depending on the age of the patient, the methods of application differ slightly. For the treatment of adults, the solution is prepared according to the following instructions:
- Pour 100 ml of clean and well-warm water into a measuring container.
- The sprayer is turned to the side to open.
- To treat an adult, you need to take 10 ml of the drug per 100 ml of well-warm water. One press on the nebulizer allows you to add only 2 ml of medicine, therefore, you need to press the nozzle 5 times.
- Mix the resulting solution thoroughly and immediately begin to gargle.
Rinsing is carried out two to three times a day.
For mild inflammation, it is enough to gargle just once a day. At one time, gargle with the collected liquid for about 30 seconds. If the disease is very severe, then in between gargles the doctor may recommend irrigating the throat with a spray. To do this, you need to make just one click on the spray nozzle. This treatment can be supplemented by taking OKI powder. This medicine is used if there is a high fever and severe pain. The granules are pre-diluted in a small volume of water and the resulting solution is taken during meals.
To reduce pain and reduce temperature in adults, it is advisable to prescribe OKI suppositories. This medicine can only be used to treat patients who are over 18 years of age.
People with severe mental illness should gargle under the supervision of a health professional or family member. It is unacceptable to leave alone those people whose condition is very disturbed due to illness.
Treatment with all drugs called OKI must be prescribed by a doctor. You should not resort to self-medication, as the condition may worsen greatly.
Features of treatment for children
For the treatment of children, a solution of lower concentration is prepared. It should be remembered that according to the instructions, the solution can only be used for rinsing from 6 years of age; at a younger age, the drug can cause severe intoxication.
Children aged 6-10 years need to prepare a solution from 100 ml of water and 4 ml of OKI, which is equal to two clicks on the spray nozzle. For children 10-15 years old, the solution is prepared from 100 ml of water and 6 ml of spray, which is equivalent to three presses on the sprayer.
Before starting the procedure, the child must be explained in a clear manner that the medicine should not be swallowed. If this happens, the child must immediately tell adults so that they can provide first aid.
While gargling, a sick child should be under the supervision of parents. The child takes about 30 ml of solution at a time and gargles with it for half a minute, after which the mixture is spat out and a new one is taken.
The child should gargle with the solution only once a day. The duration of such treatment is about a week. If, when rinsing with OKI solution, a child experiences discomfort in the throat, stop the procedure and consult a doctor. In some cases, it is necessary to replace OKI with analogues, but with a milder effect.
If no improvement in the patient’s condition is observed within several days of treatment, the drug is discontinued.
Methods and rules of application
The instructions for use for each drug describe the method of use and the permissible dosage.
If we talk about granules that are used to make the solution, then the following dosage regimen is acceptable for this form:
- the drug is used 3 times a day;
- 30 minutes before meals;
- for adults, the optimal dosage is 80 milligrams;
- for children, the dose is reduced to 40 milligrams.
Method of administration of the medication in the form of rectal suppositories:
- For elderly patients: no more than 2 suppositories per day.
- For other patients, it is permissible to use the following regimen: 1 suppository 2-3 times a day.
Drugs in any form of release have their own additional contraindications. Suppositories are not recommended for use in the presence of diseases of the digestive system.
OCI can be used as a gargle in the form of a solution for topical use. In this case, the drug is used:
- diluting with warm water; for adults, it is recommended to use 10 milliliters of solution per 1 rinse or 5 injections if the drug is used in the form of a spray;
- Children and adolescents under 12 years of age are recommended to use no more than 6 milliliters of solution per rinse.
As a rinse (topical application), the medicine is used according to the following scheme:
- Prepared in a separate glass, it is included in the package.
- One spray corresponds to 2 milliliters of solution.
Detailed instructions for using Oka solution for gargling
Oki is the trade name of a non-steroidal anti-inflammatory drug produced by the Italian company Dompe Farmaceutici. The medicine is widely used in otolaryngological practice.
Operating principle
Okie:
- suppresses inflammation by inhibiting the enzymes cyclooxygenase I and II (cox-1 and cox-2), responsible for the synthesis of prostaglandins;
- pain relief (reducing inflammation will automatically reduce pain, in addition, menthol has a distracting and cooling effect);
- relieves swelling (also by suppressing the synthesis of prostaglandins).
This activity makes the drug Oki for gargling - a means of symptomatic treatment. But it does not give it the opportunity to suppress the reproduction of pathogenic agents. This is especially important to remember when it comes to bacterial infections of the throat, for example, sore throat, which requires the mandatory use of antibiotics.
How to use for rinsing?
Although Oki is a solution for topical use, it must be diluted with water before gargling.
To do this, take 5 doses of the medicine (automatically measured with a dispenser, one actuation of which is equal to 2 ml). Dilute with 100 ml of water.
To prepare the solution, children from 6 to 12 years old take 3 doses of Oka per 100 ml of water.
The frequency of the procedure is 2 times a day. Duration of treatment is 4-5 days.
The rinse itself with Oka solution is carried out in the same way as with any other means for local treatment of the throat:
- take a sip of the solution into your mouth and throw your head back;
- pronounce the letter “Y” for several seconds (the longer, the better);
- repeat until all the solution in the glass has dried up;
- After finishing the procedure, refrain from eating and drinking for at least half an hour.
Side effects
If you gargle correctly and do not swallow the raster, you may develop an allergy. This may include an anaphylactoid reaction, swelling of the mouth and throat, or periorbital edema.
If the solution gets inside, general side effects may occur:
- from the gastrointestinal tract - stomach pain, nausea, diarrhea, changes in the activity of renal enzymes;
- from the nervous system - dizziness, tremor, anxiety or drowsiness, blurred vision, headache;
- the skin can give urticaria, erythematous exanthema, erythema.
Cystitis, leukocytopenia and leukocytosis, a rise or fall in blood pressure, tachycardia and heart pain may occur.
All of the listed side effects, except allergies, develop only against the background of regular use of Oka as a means of oral administration. This is how joint diseases and some other diseases are treated.
Use special tablets to prepare solutions for oral use. If the rinse solution is accidentally swallowed, the likelihood of such adverse reactions occurring is negligible.
Interaction with other drugs
Using Oka's gargling solution goes well with any other medications used in otolaryngology:
- antibiotics;
- antiviral and fungicidal agents;
- local anesthetics (lozenges, lozenges, sprays).
At the same time, there are medications that cannot be combined with the use of Oka. This:
- diuretics;
- anticoagulants;
- lithium preparations;
- methotrexate.
You should not combine rinsing with this drug and taking other non-steroidal anti-inflammatory medications, for example, aspirin or Ibuprofen.
Analogs
There are no complete analogues in which ketoprofen is the main active ingredient.
However, in the broad sense of the word, any pharmaceutical preparations and home remedies that reduce sore throat and relieve swelling can be considered analogues of Oka.
Gargling with Oka's solution often has such a strong analgesic effect that a person may feel like he is recovering. If he has a bacterial infection, such a sensation can be dangerous, as it will cause the patient to unreasonably refuse to use antibiotics.
Therefore, be careful. And remember that ketoprofen only reduces inflammation and pain, but does not destroy pathogenic bacteria, fungi and viruses.
Source: https://gorlolor.ru/ru/lekarstva/oki/
What are the side effects?
Side effects occur due to incorrect use of the drug, they can also be a consequence of a hypersensitivity reaction.
During therapy, the following undesirable side effects appear:
- Allergic reactions of various kinds. This includes the appearance of rashes on the skin: hives, rash accompanied by itching and burning.
- Abdominal pain, discomfort, diarrhea, disturbances in the functioning of the gastrointestinal tract, with the development of erosive and ulcerative changes.
- Headaches, dizziness, hallucinations, irritability, frequent mood swings.
- Frequent urge to painful urination, swelling, the appearance of red blood cells in the urine.
- Bronchial spasms, increased levels of leukocytes in the blood.
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With prolonged use, the functioning of the liver and kidneys is disrupted, which leads to an increase in bilirubin levels, the development of hematuria and other unwanted side effects. To avoid this phenomenon, you should give preference to a course method.
If the patient has a history of problems with the liver and kidneys, then the medication should be used with caution.
Indications for use
Most often, Oki is used for rinsing when:
- laryngitis;
- stomatitis;
- pharyngitis;
- tonsillitis;
- gingivitis;
- glossitis;
- periodontitis;
- various types of ulcerative formations.
It is not recommended to use the solution if you have:
- blood clotting is impaired;
- stomach ulcer;
- bronchial asthma;
- late pregnancy;
- lactation period;
- intolerance to ketoprofen.
It is not advisable to use Oki for children under six years of age. Side effects manifest themselves in the form of an allergic rash and runny nose. Sometimes there is so-called “aspirin” asthma.
Can it be taken by children?
The drug is not recommended for children under 12 years of age. If we are talking about a child under 6 years old, then the product is not used, even in the form of rectal suppositories. Although this form is considered safe.
Children's age is not an absolute direct contraindication; for this reason, it is worth discussing the possibility of starting treatment with this remedy with a doctor.
When it comes to infants, the drug is not used for them. A woman who has started treatment that includes OKI is recommended to breastfeed her baby. Lactation is resumed after completion of therapy.
Effective analogues
OKI has analogues with a more affordable price. The following medications may be included in this list:
- Ketoprofen in gel form. It is applied to damaged areas in order to reduce the severity of pain.
- Ketoprofen in ampoules. Used as a local anesthetic.
- Ketonal in the form of rectal suppositories. Used as an antipyretic and analgesic drug.
- Ketonal in tablet form.
Attention! All of the analogues described above are considered structural, that is, they have one active substance.
Therapy adjustment is required only if undesirable side effects develop; it is carried out under the guidance of a doctor, taking into account the patient’s complaints.
OKI is considered a new generation drug; its use helps relieve a person from pain. But, like all NSAIDs, this medication puts “pressure” on the liver and kidneys, which can permanently disrupt the normal function of these organs.
To avoid undesirable consequences of treatment, doctors advise carefully following the recommendations and not self-medicating. This can keep you healthy and get rid of pain.
Medicinal product OKI - application
You need to mix the OKI solution for gargling immediately before the procedure; you cannot leave the prepared mixture for the next session. Use lukewarm water; hot water negates the effect of the main component - ketoprofen. At the initial stage, it is recommended to rinse 1-2 times a day, for complicated diseases - from 5 to 7 times.
How to dilute OKI for gargling?
Since the drug is classified as a non-steroidal drug, doctors recommend using OKI powder for the throat for no more than 3-4 days. It is better to do this after eating, since the drug affects the sense of taste. It is advisable not to swallow the solution, but if this happens in a small dose, there is no need to worry; side effects can only appear in case of a severe overdose.
Recommendations on how to prepare a solution for OCI throat from granules:
- for adults, dilute 80 mg per 0.5 tbsp. water;
- for children under 14 years old, dilute 40 mg per 0.5 tbsp. water.
How to gargle with OKI solution?
Very carefully you need to measure doses of OKI for gargling a sore throat for diabetics, since this composition increases the effect of insulin. Likewise, it enhances the effect of blood clotting drugs, so recalculation of dosages is extremely necessary. In all other cases, the medicine is measured according to the instructions, the rinsing procedure is the same when using different drugs.
The easiest way to use OKI for gargling:
- Sip a little solution into your mouth.
- Throw your head back and say the letter “y”.
- Extend the sound to 30-40 seconds.
- Repeat the action several times.
- After the procedure, do not eat or drink for half an hour.