Is there a big difference between Amoxicillin and Amoxiclav? Which one is better?

Antibacterial agents Amoxicillin and Amoxiclav are often prescribed for the same diseases, since they belong to the penicillin series. But despite the similarity in composition, their spectrum of action is somewhat different.

Antibacterial agents Amoxicillin and Amoxiclav are often prescribed for the same diseases, since they are penicillin drugs

Antibacterial agents Amoxicillin and Amoxiclav are often prescribed for the same diseases, since they belong to the penicillin series.

Compound similarities

The main similarity of these antibiotics is that they belong to the same group - penicillins. The medications are also similar in that they are used in the treatment of not only adults, but also children, since they have a small number of contraindications.

These drugs are similar in their mechanism of action. They destroy the walls of microorganisms, preventing pathogenic microflora from multiplying. Patients who want to know more about drugs should familiarize themselves with their characteristics.

The active substance of Amoxicillin is amoxicillin dihydrate. The drug is produced in several forms - film-coated tablets, suspension, convenient for use by children, and capsules. The medication begins to act quickly - approximately 20-30 minutes after ingestion. The antibiotic acts on the body for 7-8 hours.

Amoxicillin begins to act quickly - approximately 20-30 minutes after ingestion

Amoxicillin begins to act quickly - approximately 20-30 minutes after ingestion.

Amoxicillin affects a number of gram-positive, gram-negative, anaerobic bacteria and some others. Indicated for the following pathologies:

  • intestinal infections, peritonitis, cholecystitis;
  • urethritis, gonorrhea, pyelonephritis;
  • infections developing in soft tissues;
  • sepsis;
  • as part of the complex treatment of gastrointestinal ulcers, gastritis caused by the bacterium Helicobacter pylori.

Amoxiclav is more effective because it contains 2 active components - amoxicillin trihydrate and the potassium salt of clavulanic acid. Forms of release of the drug: film-coated tablets, dispersible tablets, powder for suspension, lyophilisate for injection solution.

Amoxiclav is not only an antibiotic, it also has bactericidal properties. The drug has a negative effect on most bacteria, so it is often prescribed for infections for which the causative agent has not been identified. The medication is indicated for use in the following pathologies:

  • exacerbation of chronic sinusitis;
  • Chronical bronchitis;
  • sore throat, pneumonia, otitis media;
  • infections developing in the urinary system;
  • gynecological pathologies of infectious origin;
  • infections developing in soft tissues;
  • gonorrhea, chancroid;
  • odontogenic infectious diseases;
  • combined infectious pathologies caused by bacteria of different types;
  • complications arising after sepsis.

What are the similarities and differences between the drugs?

Despite the presence of the same antibiotic in the composition, the difference between Amoxicillin and Amoxiclav can be seen quite clearly, but only for doctors. For patients, both drugs remain similar, since they have the same indications:

  • infections of the respiratory system and ENT organs;
  • suppuration and inflammation of bone tissue and skin;
  • inflammatory processes of the gallbladder, stomach and sometimes intestines;
  • urological, venereological, gynecological diseases.

Experts note that in terms of indications, Amoxiclav and Amoxicillin have a significant difference. Amoxiclav is suitable for treating infections caused by all strains of gram-positive bacteria, while Amoxicillin does not have such a wide spectrum of action.

The second difference between Amoxiclav and Amoxicillin is the frequency of side effects. With a single-component antibiotic, they are more pronounced and appear more often. Experts attribute this to the fact that in the absence of clavulanic acid, patients are forced to take large doses of the drug. When using Amoxiclav, side effects occur 2-3 times less often.

The list of contraindications in the instructions for Amoxiclav and Amoxicillin indicate the same thing: individual intolerance to the components, allergies to penicillins (including asthmatic attacks), mononucleosis, lymphocytic leukemia and serious liver and kidney diseases.

Another point where the difference between Amoxiclav and Amoxicillin can be seen is the release form. This difference is not decisive when choosing one of the antibiotics. Amoxicillin has more forms due to the release of drugs for external or local use, tablets, capsules and suspensions - you can always choose the most convenient form for a child and an adult. Amoxiclav is available only in tablets, capsules, powders and ready-made solutions for injection.

Which is cheaper?

Comparing the cost of Amoxiclav and Amoxicillin, you can see that the two-component antibiotic is more expensive. The average price of one package of Amoxiclav is about 250-350 rubles for 14 tablets or 250 rubles for 100 ml of injection solution. Any dosage form of Amoxicillin will cost much less: from 35 rubles for a package of 20 tablets and about 100 rubles for 100 ml of injection solution.

Which is better according to reviews

The first thing patients try to pay attention to when choosing Amoxicillin or Amoxiclav is real reviews from doctors and ordinary people who have taken the drugs. Both specialists and their patients speak generally well of both remedies. Amoxiclav has slightly more positive ratings, since it is used in situations where Amoxicillin does not help.

Is it possible to replace one with the other?

Complete interchangeability of antibiotics is possible only if the detected bacteria do not synthesize penicillinase. In this case, Amoxiclav can be replaced with Amoxicillin without the risk of worsening the infection. If an enzyme is detected in tests, replacement is not advisable. In a situation where Amoxicillin is ineffective, most doctors replace it with Amoxiclav as a stronger antibiotic. Due to its milder effect on the body, it can be prescribed to children and even pregnant women, but only in the absence of direct contraindications to the use of penicillins.

If for some reason it is not possible to be treated with a prescribed antibiotic, you can replace it with an analogue only after consulting a doctor. You should not save by purchasing more affordable Amoxicillin if your doctor has prescribed Amoxiclav, as the drug may be ineffective. Remember this and do not expose your health to additional risks.

Differences between Amoxicillin and Amoxiclav

The main difference is that Amoxicillin is a single drug, i.e. it contains only 1 active ingredient, while Amoxiclav contains 2 active ingredients. This expands the spectrum of action of the antibiotic on the microorganisms that cause the disease.

Amoxiclav contains 2 active components. This expands the spectrum of action of the antibiotic on the microorganisms that cause the disease.

Amoxiclav contains 2 active components. This expands the spectrum of action of the antibiotic on the microorganisms that cause the disease.

Composition and pharmacological action of Amoxiclav

Amoxiclav is an antibacterial drug, a combination product from a series of penicillin medications of semi-synthetic origin. The antibiotic contains clavulanic acid and the substance amoxicillin. The main effect is bactericidal, aimed at inhibiting various types of bacteria, gram-positive or gram-negative. Used for the treatment of streptococcal and staphylococcal infections.

Clavulanic acid, when it gets on the tonsil tissue, can inactivate the enzyme penicillinase, which opens the way to bacteria. The concentration of the constituent components of the drug is calculated in such a way that the entire contents of the medication in maximum quantities reach the cells of microorganisms and show a good result in destroying bacteria. Accordingly, for the treatment of sore throat caused by bacteria, it will be better than using pure amoxicillin.

This antibiotic has certain indications for use and is recommended for the following diseases:

  • Acute or chronic sinusitis
  • Otitis media
  • Retropharyngeal abscess
  • Pneumonia
  • Urinary and biliary tract infections
  • Gynecological infections
  • Skin infection
  • Infectious lesions of bone and joint tissue
  • For preventive purposes in the postoperative period occurring with purulent-septic complications
  • During surgical operations of the maxillofacial direction
  • In orthopedics.

In practice, to determine the nature of the infection, the doctor prescribes a bacterial culture, which the laboratory does for about 4 days. But, for example, a sore throat needs to be treated from the first day, so the specialist immediately prescribes Amoxiclav drugs. Because its effect will be better than other medications.

But when prescribing such a drug, the doctor is obliged to take a swab from the throat to be sure that the treatment is correct. No matter how good Amoxiclav is, the patient may experience allergic manifestations with the development of side effects. In addition, after the analysis, another disease, tonsillomycosis, can be diagnosed. With this pathology, antibiotics have no effect; antifungal agents are prescribed instead.

Side effects that the drug may cause:

  • Digestive disorders (nausea and vomiting, diarrhea and dyspepsia, flatulence, gastritis and anorexia, stomatitis)
  • Impaired liver function, with the development of cholestatic jaundice
  • Rash, swelling, urticaria
  • Headache and dizziness, insomnia and hyperactivity
  • Convulsions, inappropriate behavior
  • Exanthematous pustulosis and erythema
  • Crystallurgy
  • Provoking interstitial nephritis.

Contraindications will be:

  • Individual intolerance to the drug
  • Hepatitis
  • Pregnancy and lactation period.


Medicines have the same contraindications:

  • special sensitivity to the components included in the drug;
  • lymphocytic leukemia, infectious mononucleosis;
  • liver diseases associated with the use of the active components of Amoxicillin and Amoxiclav;
  • respiratory infections caused by viruses;
  • bronchial asthma;
  • diathesis of allergic origin;
  • hay fever.

Dispersible tablets are not prescribed to children and patients with kidney disease.

Antibiotics can be used in the treatment of pregnant women and during lactation, but with caution. The appointment must be made by a doctor. Therapy is carried out under the supervision of a specialist.

Amoxicillin or amoxiclav: which is better and what is the difference (differences in composition, reviews from doctors)

Amoxicillin or Amoxiclav is prescribed to treat pathologies caused by bacterial infection. The drugs have the same mechanism of action on the body, but sometimes they achieve different therapeutic effects.

Amoxicillin or Amoxiclav is prescribed to treat pathologies caused by bacterial infection.

What is the difference

Amoxiclav has a large list of contraindications due to its resistance to beta-lactamase produced by some bacteria. The drug has less negative effects on the intestinal microflora and is less likely to provoke the development of allergic reactions and side effects. Amoxicillin has more forms of release.

Amoxicillin, which is used for sore throat, otitis media and sinusitis, is sold in pharmacies at a price of 95 rubles.

What is more effective

Amoxiclav, due to its enhanced composition, has a larger list of indications and is resistant to destruction under the influence of an enzyme produced by bacteria.

Which is better - Amoxicillin or Amoxiclav

For uncomplicated infections, preference is given to Amoxicillin; the ineffectiveness of this drug within 2 days of treatment requires its replacement with Amoxiclav. The combination drug is prescribed if it is not possible to quickly determine the type of pathogen.

How to use

The dosage and duration of therapy depend on the patient’s age, the condition of his internal organs (kidneys and liver), and the severity of the disease. The doctor makes the appointment.

Amoxicillin is recommended to be taken with food. For infectious pathologies, 500 mg of antibiotic is most often prescribed 3 times a day. The duration of treatment is from 1 to 2 weeks.

Amoxiclav is recommended to be taken after meals. For moderate infections, 500/125 mg is prescribed 2 times a day. The duration of treatment depends on several factors, including the location of the infection.

Pharmacology of amoxicillin drug

Amoxicillin is an antimicrobial agent of the semisynthetic penicillin group, the effect of which is aimed at inhibiting aerobic gram-positive bactericidal microorganisms.
The main component is amoxicillin. It has a wide range of applications - this is the treatment of infectious diseases of the respiratory tract, urinary system, kidneys, skin, as well as gynecological diseases of an infectious nature. The antibiotic is perfectly absorbed in the body, with no side effects. But it is not recommended for the treatment of bacterial sore throat, because... such microorganisms exhibit increased resistance to penicillin.

An antibiotic is recommended in case of infection caused by microorganisms with hypersensitivity:

  • For ENT diseases such as otitis media, tonsillitis, sinusitis and pharyngitis
  • Diseases of the bronchi and lungs - pneumonia, bronchitis
  • Pathologies of the urinary and reproductive systems, biliary tract - cystitis, urethritis and prostatitis, pyelonephritis, simple gonorrhea, cholestitis and cholangitis
  • Skin tissue lesions - phlegmon, wound infection
  • Infection of joints and bones – chronic osteomyelitis.

The following contraindications have been identified when using the drug:

  • Hypersensitivity to the main components of the product
  • Allergic manifestations to medications of the penicillin and cephalosporin group
  • For infectious mononucleosis
  • Lymphocytic leukemia.

In addition, side effects may occur:

  • Allergies in the form of urticaria, angioedema, erythema, rhinitis and conjunctivitis
  • Pain in joints and muscles
  • Fever
  • Anaphylactic shock (in rare cases)
  • Vomiting attack, anorexia
  • Constipation or, conversely, diarrhea
  • Colitis
  • Erythema multiforme, cholestatic jaundice, hepatitis
  • Toxic epidermal necrolysis, etc.

The drug is also not prescribed for problems associated with the functioning of the kidneys and liver. The dose must be clearly adjusted, and patients must be under the supervision of the attending physician. The pediatric dosage is determined by the pediatrician; it is not recommended to prescribe an antibiotic on your own.

Reviews from doctors

Olga, gynecologist, Chelyabinsk: “Amoxiclav is an effective antibiotic. I prescribe it for infectious diseases of the genital organs. But over time, bacteria become immune to the drug, so other drugs have to be selected.”

Pavel, therapist, Kaluga: “These antibacterial agents are not the same thing. Amoxiclav is much more effective than Amoxicillin in treating respiratory tract infections. I prescribe patients a 5-day course of therapy, after which I recommend medications that restore the microflora. There were no negative reviews. Patients do not complain of side effects."

Amoxiclav or amoxicillin

For colds and viral diseases, we are often prescribed antibiotics, which help the human body to recover quickly. The treating doctor prescribes a drug that is better suited for treating a particular disease or is easier to tolerate by the patient. What is the difference between one drug and another?

The difference between amoxiclav and amoxicillin

  1. Amoxiclav is an antibiotic that has been used everywhere in medical practice for almost thirty years. This drug Amoxiclava is made on the basis of natural and chemical components; it is classified as penicillins of semi-synthetic origin. Amoxiclav contains clavulanic acid and Amoxicillin. This antibiotic Amoxiclava has a good effect on bacteria, its action binds the bacterial membrane, while clavulanic acid together with Amoxicillin creates a complex barrier to the creation of new pathogenic microbes and provides reliable protection against further development of the disease.
  2. Amoxicillin is an antimicrobial drug and belongs to the group of semi-synthetic penicillins. This Amoxicillin medicine has an antimicrobial effect, is easily absorbed and penetrates into the blood through the gastrointestinal tract, where it prevents the growth of bacteria and Amoxicillin accelerates the healing process. This antibiotic is used in the treatment of infectious diseases of the respiratory system, inflammatory processes in the kidneys and genitourinary system, as well as for diseases of the skin.

The different effects of the described drugs indicate the presence of clavulanic acid, the properties of which significantly expand the possibilities of action of the main component. The antibiotic Amoxicillin is a drug based on ampicillin ; it also has an antibactericidal effect on the cell membranes of bacteria.

A significant disadvantage of a drug such as Amoxiclav is that it is completely defenseless against the production of lactamase, and in Amoxicillin preparations this action is performed by clavulanic acid. Now the drug amoxiclav is prescribed for the treatment of streptococcal diseases, but is occasionally used in the treatment of staphylococcal infectious diseases, because the pathogens are able to adapt to the environment and addiction to the drug occurs.

Choice of antibiotic

One type of antibacterial agent, such as Amoxiclav, has a weak effect or does not give a positive result, while others, on the contrary, have a more pronounced effect. When treating emerging infectious diseases, there are certain conditions for the attending physician to prescribe one or another antibiotic, depending on the difference that the antibiotics have in their composition.

Pediatricians begin treatment of their patients with the penicillin series of weaker antibiotics, such as Amoxiclav, and the selected antibacterial agent is prescribed in accordance with the disease and the results of laboratory tests.

The best choice of drug is considered to be one that is completely suitable for the identified disease, which is determined by an antibiogram and laboratory culture of bacteria. Such a study gives the best result for choosing an antibiotic.

Sometimes treatment with antibacterial agents does not produce a positive effect, and then treatment with antibiotics from a different group, which differ in composition, is prescribed, which most often gives a positive result.

Amoxiclav has an advantage over Amoxicillin only in its cost ; it is much cheaper in comparison with other drugs of the antibacterial group, but Amoxiclav is inferior in its properties to more expensive drugs .
Medicines are available in the form of tablets, powder and capsules.

Patient reviews

Yulia, 31 years old, Yuzhno-Sakhalinsk: “The pediatrician prescribed Amoxicillin to my daughter several times. The drug is effective, the child tolerates it well. But we take the pills as prescribed by the doctor. This is an antibiotic, so you cannot prescribe it yourself. The good thing about the medicine is that it is inexpensive and can be bought in many pharmacies.”

Inna, 39 years old, Petropavlovsk-Kamchatsky: “I often suffer from laryngitis and pharyngitis. Amoxiclav copes well with these diseases, but it is an antibiotic, so the microflora is disturbed after treatment. I do not recommend it to children, because dysbacteriosis is guaranteed. If a doctor prescribes a drug, he also prescribes other medications that normalize the microflora. We must follow the doctor’s recommendations.”

Svetlana, 27 years old, Kostroma: “Because of problems with the thyroid gland, I’m afraid to take any medications. But I recently got sick. The doctor said that the infection had entered the respiratory tract, so I needed to take an antibiotic. Prescribed Amoxicillin. I took it for 5 days. There were no side effects. The disease has passed."

Amosin or amoxicillin: which is better and what is the difference (differences in composition, reviews from doctors)

For inflammatory diseases caused by bacteria, doctors often prescribe penicillin antibiotics. The list of the most popular drugs includes Amosin and Amoxicillin. These medications contain the same active substance - amoxicillin - and have similar effects. Meanwhile, patients often wonder which remedy is better.

Characteristics of Amosin

Amosin is an antibacterial drug that belongs to the group of semisynthetic penicillins. It is a broad-spectrum antibiotic to which many aerobic gram-positive and gram-negative bacteria are sensitive.

Amosin is available in several dosage forms:

  • tablets with a dosage of 250 mg;
  • tablets with a dosage of 500 mg;
  • capsules containing 250 mg of active substance;
  • powder with a dosage of 500 mg (it is used to prepare a suspension).

Amosin is an antibacterial drug that belongs to the group of semisynthetic penicillins.

Characteristics of Amoxicillin

The active composition of Amoxicillin contains the component of the same name, which has an antimicrobial effect. It is highly effective in fighting bacteria, but viruses and fungi are not sensitive to it.

The medicine has several forms of release:

  • capsules (or tablets) with a dosage of 250 mg of active ingredient;
  • capsules and tablets containing 500 mg of medication;
  • powder used to prepare a suspension.

Comparison of Amosin and Amoxicillin

A superficial study of the instructions for Amoxicillin and Amosin can come to the conclusion: the drugs have many similar characteristics. Meanwhile, a more detailed examination allows us to identify several differences.

Indications for use

Both drugs are prescribed for diseases of bacterial origin. The list of diagnoses for which medications are highly effective:

  • diseases of the respiratory system - pneumonia, bronchitis, tracheitis;
  • infectious pathologies of the ENT organs (sinusitis, otitis media, sinusitis, pharyngitis);
  • inflammation of the urinary system (cystitis, pyelonephritis, urethritis);
  • development of endocarditis;
  • inflammatory diseases of the gastrointestinal tract (cholecystitis, dysentery, salmonellosis, etc.);
  • infections of soft tissues and skin (erysipelas, impetigo, dermatosis).


In addition to general indications for use, medications have similar contraindications. Amoxicillin and its analogue Amosin are strictly not recommended for use in the following conditions:

  • individual intolerance to one of the components of the composition;
  • hypersensitivity to the penicillin series;
  • bronchial asthma;
  • severe digestive disorders;
  • hay fever;
  • renal failure or other severe renal dysfunction;
  • acute lymphoblastic leukemia;
  • patient age 0-3 years;
  • allergic diathesis;
  • severe liver disease;
  • infectious mononucleosis.

Time of action

After oral administration, the effect of the medication lasts for 8 hours, so the frequency between taking the next dose of the antibiotic is the same in both cases.


Amosin and Amoxicillin are produced in tablets and capsules with a dosage of 250 and 500 mg. 1 ml of the prepared suspension of these drugs contains the same concentration of the active substance.

Side effects

The body's response to these antimicrobial drugs will be the same in adult patients. The list of possible side effects:

  • nausea, vomiting, changes in stool, abdominal pain, feeling of bloating, changes in taste;
  • from the central nervous system, confusion, anxiety, sleep disturbances, dizziness are possible;
  • if you are intolerant to the components of the composition, allergic reactions may occur (urticaria, itching, erythema, conjunctivitis, swelling);
  • tachycardia;
  • hepatitis;
  • anorexia;
  • anemia;
  • in patients suffering from reduced body resistance, fungal and viral infections may occur;
  • nephritis.

The similar composition of the drugs and their possible side effects indicate that if one of these antibiotics is intolerant, the patient will have an identical reaction to the second drug.


These antimicrobial drugs should be taken with extreme caution in diabetes mellitus. For nursing and pregnant women, the medicine should be prescribed under the supervision of a doctor and with dosage adjustment.

Which is better – Amosin or Amoxicillin

There is no qualitative or quantitative difference in the active composition of the drugs, which indicates a similar effect and equal effectiveness. Amoxicillin and Amosin are equivalent penicillin antibiotics and can be used interchangeably.

The simultaneous use of two medications is strictly prohibited, as these actions lead to an overdose. It is accompanied by the following symptoms:

  • water-electrolyte imbalance;
  • nausea, repeated vomiting;
  • anaphylactic shock;
  • diarrhea.

Patient reviews

Veronica, 34 years old, Astrakhan

I was cold at work and in the evening my ear hurt. I saw the doctor the next day. They diagnosed otitis media and prescribed comprehensive treatment. Amoxicillin tablets were prescribed as an antibiotic.

I took the medicine according to the prescribed regimen. On the second day the pain became less. The doctor warned about possible side effects, but there were none. I took the full course of pills, as the doctor advised.

Natalia, 41 years old, St. Petersburg

My son was diagnosed with laryngitis. There was a high temperature, hoarseness and cough. The pediatrician recommended Amoxicillin suspension. The child did not even have to be forced to drink the medicine - the suspension smells good and tastes sweet. Within 5 days the symptoms were completely gone.




Characteristics of drugs

The drugs are semi-synthetic antibiotics of the penicillin series. The active ingredient of both is amoxicillin.


Available in capsules and tablets in dosages from 0.125 g to 1 g. For children, the medicine is produced in granules to prepare a suspension. The release form and dosage depend on the manufacturer. Trade names may differ from each other. The main thing is to look at the active ingredient of the antibiotic offered by the pharmacist.

The medication is active against gram-positive and gram-negative aerobic microbes. Prescribed for infections caused by:

  • staphylococci;
  • streptococci;
  • Neisseria, including meningococcal;
  • coli;
  • salmonella;
  • pneumococci;
  • Helicobacter pylori, the presence of which in the gastrointestinal tract causes gastritis and ulcers.

In clinical practice it is prescribed for:

  • infections of the upper and lower respiratory tract (usually pneumonia, bronchitis);
  • prolonged rhinitis, sinusitis, sinusitis, tonsillitis;
  • diseases of the kidneys, bladder;
  • bacterial lesions of the skin and soft tissues;
  • meningitis.

Also included in the treatment of stomach ulcers, because it is resistant to acidic environments.

The drug is not prescribed in the following cases:

  • during pregnancy and breastfeeding;
  • allergic reaction to components;
  • liver failure in the stage of decompensation;
  • leukemia and mononucleosis;
  • bronchial asthma and hay fever.

Children under 3 years of age are prescribed only a suspension.

Amoxicillin is well tolerated. Rarely possible:

  • allergic reactions;
  • dyspeptic disorders;
  • changes in blood formula;
  • headaches, dizziness.

Cases of overdose are rare. More often observed in children of the first year of life during self-medication. Against the background of the underlying disease, the child experiences: frequent vomiting, convulsions, lack of response to habitual stimuli, drowsiness, and mental retardation. First aid in such a situation is to try to rinse the stomach and call an ambulance.

Amoxicillin is well tolerated, allergic reactions are very rarely possible.


In addition to amoxicillin, the medicine contains clavulanic acid. The medication is available in 3 forms:

  • tablets: 250+125, 500+125, 875+125 mg;
  • powder: 500+100, 1000+200 mg – used for intravenous and intramuscular administration in dissolved form;
  • powder for the preparation of suspension for oral administration: 125, 200 and 400 mg.

The same types of bacteria are sensitive to Amoxiclav as to Amoxicillin. The main difference is that the drug is effective in treating diseases caused by resistant strains.

The drug is widely used to treat acute and chronic bacterial infections. Prescribed for the treatment of lung diseases, urology, gynecology. Bone diseases, sepsis, prevention of postoperative infections - indications for the use of the drug. Proven effectiveness in pediatrics. In the first 3 months of life, a suspension of 125 mg is prescribed.

The following side effects are possible while taking an antibiotic:

  • nausea, diarrhea;
  • rash, itchy skin;
  • headache, dizziness.

The medication is not used for allergies to penicillin antibiotics and jaundice caused by the patient's history of using amoxicillin.

Prescribe the drug with caution in case of renal failure, especially if renal creatinine clearance is less than 30 ml/min.

The antibiotic can be taken during lactation. During pregnancy, it is prescribed for health reasons under the supervision of a doctor.

Cases of overdose of Amoxiclav are rare. As with Amoxicillin, this is self-medication for children under one year of age. The clinical picture and first aid for overdose are similar. The main thing is to urgently call an ambulance.

The following side effects are possible while taking Amoxiclav: nausea, diarrhea.

Comparison of side effects of Amoxiclav and Amosin

Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.

Amoxiclav has more side effects than Amosin. This implies that the frequency of their occurrence is low in Amoxiclav and low in Amosin. Frequency of manifestation is an indicator of how many cases of an undesirable effect from treatment are possible and registered. The undesirable effect on the body, the strength of influence and the toxic effect of drugs are different: how quickly the body recovers after taking it and whether it recovers at all. When using Amoxiclav, the body's ability to recover faster is higher than that of Amosin.

Comparison of the effectiveness of Amoxiclav and Amosin

Amoxiclav is more effective than Amosin - this means that the ability of the medicinal substance to provide the maximum possible effect is different.
For example, if the therapeutic effect of Amoxiclav is more pronounced, then with Amosin it is impossible to achieve this effect even in large doses.

Also, the speed of therapy is an indicator of the speed of the therapeutic action; Amoxiclav and Amosin are also different, as is bioavailability - the amount of a medicinal substance reaching the place of its action in the body. The higher the bioavailability, the less it will be lost during absorption and use by the body.

Functional similarities of drugs

Both antibiotics help cope with infectious diseases of the same nature. They are absorbed from the gastrointestinal tract and eliminated by hemodialysis . Each of the medications negatively affects the effectiveness of oral contraception.

The list of contraindications for the use of each drug is the same, as is the list of side effects. At the same time, “Amoxicillin” and “Amoxiclav” can be used during pregnancy and breastfeeding, taking into account the excess of the benefit for the woman over the danger to the fetus.

With the classical treatment regimen, the dosages of the drugs are similar.

The absorption of each drug increases with parallel intake of ascorbic acid, and decreases with the use of laxatives and glucosamine.

Comparison of addiction between Amoxiclav and Amosin

Like safety, addiction also involves many factors that must be considered when evaluating a drug.

Thus, the totality of values ​​of such parameters as “syndrome o” in Amosin is less than the similar values ​​in Amoxiclav. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible.

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