Flemoklav solutab or amoxiclav difference

Medicines Augmentin or Flemoklav Solutab are used in the treatment of pathologies that are caused by a bacterial infection. Despite the fact that these drugs are included in the same group of antibiotics, they have different principles of action and effectiveness.

Medicines Augmentin or Flemoklav Solutab are used in the treatment of pathologies that are caused by a bacterial infection.

Characteristics of Augmentin

The drug Augmentin contains both clavulanic acid and amoxicillin. It is available in the form of an injection solution, a powdery substance for the preparation of an oral suspension and film-coated tablets. Several forms of release make the use of this medication extremely convenient.

Tablets have a dosage of 650, 375 or 125 mg. Additional components of the drug:

microcrystalline cellulose;
silicon dioxide;
magnesium stearate.

How does Flemoclav Solutab work?

The prefix “Solyutab” in the name of the drug means that it is produced using innovative technology. The medicine is produced in the form of soluble tablets, which can have the following dosages:

1875 mg of clavulanic acid and 125 mg of amoxicillin;
62.5 mg and 250 mg;
31.25 and 125 mg.

In addition to the active ingredients, this pharmaceutical product contains apricot flavor, magnesium stearate, vanillin and microcrystalline cellulose.

Comparison of Augmentin and Flemoclav Solutab

The medicinal activity of both drugs is explained by the presence of the same active substance. Therefore, they have similar pharmacological effects, indications, side effects and contraindications.

Amoxicillin is a type of penicillin. This substance suppresses the viability of pathogens of infectious processes and chronic diseases of an infectious nature, having a negative effect on the walls of their cells. Clavulanic acid suppresses a number of enzymes that interfere with the action of penicillin antibiotics.

The combination of clavulanic acid and amoxicillin (clavulanic acid amoxil) is active against the following pathogens:

gram-negative anaerobes and protozoa;
gram-positive anaerobes (including clostridia);
corynebacteria;
enterococci;
staphylococci and streptococci.

The drugs must be prescribed by the attending physician.

The main indications for the use of Flemoklav Solutab: respiratory tract infections, community-acquired pneumonia, diseases of the ENT organs.

Similarities

The drugs contain the same active substance. The main indications for the use of these antibiotics:

respiratory tract infections (including sore throat, sinusitis, etc.);
community-acquired pneumonia;
diseases of the ENT organs;
chronic pathologies of the respiratory system;
bone infectious diseases (including osteomelitis);
other infections (including gonorrhea, pyelonephritis, cystitis, etc.).

Despite the high level of effectiveness, the combination of these active ingredients has a whole range of side effects.

Most often, negative manifestations are observed in the gastrointestinal tract (diarrhea, bloating, nausea). In addition, while using both medications, phlegm in the throat, swelling and slight dizziness may sometimes occur.

However, the drugs have similar contraindications. They are not used for liver failure, individual intolerance to penicillins, a number of diseases of the gastrointestinal tract and renal failure.

Patients with diabetes mellitus are allowed to use these drugs because they do not affect the concentration of glucose in the blood serum.

What is the difference?

The drug Augmentin is available in the form of tablets, which require a lot of time to dissolve. When using Flemoklav Solutab, a more stable absorption of the active substances is observed.

The medication Augmentin is much less often prescribed to bedridden patients, because after its use you should remain in a standing position for about 10-20 minutes. In addition, injections of a solution of this drug often cause infiltrates at the injection site. Flemoklav has no such restrictions or adverse reactions. But tablets of this drug should not be dissolved in mineral water or soft drinks.

Which is cheaper?

The cost of the drugs is determined by the dosage. A pack of Flemoclav Solutab with a dosage of 31.25 mg + 125 mg will cost 350 rubles. A similar package of Augmentin tablets costs about 285 rubles.

Which is better: Amoxiclav or Flemoklav Solutab?

Bacterial infections often occur as complications of influenza and colds.
It also happens that with a decrease in immunity, opportunistic flora is activated. To recover, many take Amoxiclav and Flemoklav Solutab prescribed by a doctor. To cure bacterial infections, many take Amoxiclav and Flemoclav Solutab prescribed by a doctor.

Characteristics of Amoxiclav

The drug is an antibiotic from the penicillin group. Available in tablets and powder for making syrup. Characterized by a wide range of effects.

The active ingredients are amoxicillin and clavulanic acid. Thanks to this combination, the drug fights microbes that secrete beta-lactamase.

Destroys gram-positive, aerobic gram-negative, anaerobic gram-positive and gram-negative bacteria.

Description of Flemoclav Solutab

Available in tablets with various dosages. The composition contains two active ingredients – amoxicillin and clavulanic acid. The medication exhibits a pronounced antibacterial effect.

It is an antibiotic from the penicillin group. Active against gram-negative and gram-positive bacteria. Leads to inhibition of peptidoglycan synthesis. Destroys gram-positive and gram-negative aerobes, gram-positive and gram-negative anaerobes.

Comparison of Amoxiclav and Flemoklav Solutab

Both drugs are broad-spectrum antibiotics. Despite this, they have not only similarities, but also differences.

Similarities

Flemoklav Solutab and Amoxiclav belong to the category of penicillins. They contain the same components - amoxicillin and clavulanic acid. Therefore, they are similar in their mechanism of action. Both medications are active against enterococci, streptococci, staphylococci, moraxella, clostridia, and bacteroides.

Penicillin antibiotics are prescribed for:

otitis media, retropharyngeal abscess, sinusitis, pharyngitis and tonsillitis;
cystitis, prostatitis;
pneumonia, acute and chronic bronchitis;
gynecological diseases;
damage to connective and bone tissues;
infection of soft tissues and skin;
cholangitis and cholecystitis.

Flemoklav Salutab is used for infection of soft tissues and skin.

They have the same list of contraindications in the form:

infectious mononucleosis;
previous liver disease or the development of cholestatic jaundice due to the use of clavulanic acid or amoxicillin;
lymphocytic leukemia;
increased susceptibility to penicillins.

The drugs are prescribed with caution for liver failure and severe kidney disease.

While taking amoxicillin, side symptoms may develop. This process is accompanied by:

loss of appetite, nausea and vomiting, diarrhea;
itching, erythematous rash, urticaria;
dizziness, headache;
insomnia, increased excitability;
crystalluria, interstitial nephritis;
candidiasis.

In rare cases, superinfection, convulsions, anaphylactic shock, angioedema, hepatitis, jaundice or pseudomembranous colitis are diagnosed.

What is the difference

The drugs differ in the form of release. Flemoklav Solutab is available only in tablets. When combined with water they become a suspension. The medicine has several dosages:

125 mg/31.25 mg;
250 mg/ 62.5 mg;
500 mg/125 mg;
875 mg/8 125 mg.

Prescribed for children over 1 year of age. The dosage is calculated based on weight.

Amoxiclav is sold in the form of tablets, powder for suspension and solution for intravenous infusion. Pharmacological companies present several dosages:

250 mg/125 mg;
500 mg/125 mg;
875 mg/125 mg;
500 mg/100 mg.

The suspension is prescribed to a child from 3 months. Tablets are indicated for children over 6 years of age.

Another difference is the country of production. Amoxiclav is made by an Austrian company. Flemoclav Solutab is produced in the Netherlands.

Which is cheaper?

The average price for Amoxiclav ranges from 118-473 rubles. Flemoklav Solutab will cost 404-489 rubles.

The average price for Amoxiclav ranges from 118-473 rubles.

Which is better - Amoxiclav or Flemoklav Solutab

The mechanism of action of the drugs is the same, since they contain the same active ingredients. The choice of medication will depend on the form of release. It is convenient for infants to give the medicine in the form of a suspension. Older children are more often prescribed dispersible tablets. They are mixed with 1 spoon of water, after which they dissolve.

If the disease is severe, amoxicillin is administered intravenously. Thus, the active substance begins to act 15 minutes after the procedure.

The choice of medication also depends on the price. Flemoclav is considered an expensive product, so patients are always looking for cheaper analogues. Amoxiclav belongs to this group.

Is it possible to replace one drug with another?

Flemoklav and Amoxiclav are considered analogues, since they are part of the penicillin group and inhibit beta-lactamase. But replacement is possible only if the patient is not allergic to amoxicillin and clavulanic acid.

Reviews from doctors and patients about Amoxiclav and Flemoklav Solutab

Roman Petrovich, 43 years old, St. Petersburg

Flemoklav and Amoxiclav are considered analogues. They contain two active ingredients: amoxicillin and clavulanic acid. Effectively cope with staphylococci, streptococci and other bacterial agents. They are prescribed not only to adults, but also to infants and older children. Well tolerated, but may cause an allergic reaction.

Valeria Aleksandrovna, 36 years old, Samara

Children are more likely to suffer from bacterial infections. To quickly combat microbes and cause minimal harm to the body, I prescribe Amoxiclav in the form of a suspension. The drug is inexpensive, has a pleasant smell and taste. But antibiotics should not be taken without consulting a doctor.

Anastasia, 29 years old, Volgograd

At the age of 3, my son was prescribed Flemoclav Solutab for pharyngitis. 2 days after the start of treatment, the temperature decreased. The sore throat completely disappeared after 5 days. The treatment lasted a week. No side effects were identified. The only negative is the high price.

Irina, 24 years old, Vladivostok

I was rarely sick as a child. If I had a cold, I recovered quickly. But six months ago I fell ill with bronchitis. I had a severe cough that made it difficult to sleep at night.

The doctor said that the disease can only be cured with antibiotics. He prescribed Amoxiclav intravenously. But a day after the administration of the medicine, a rash with itching appeared. It turned out that he was allergic to penicillins.

The drug was immediately discontinued and replaced with another.

Source: https://upraznenia.ru/amoksiklav-ili-flemoklav-solyutab.html

Patient reviews

Lyudmila, 45 years old, Ufa

My son often doesn't go to school because of a sore throat. Previously, the doctor prescribed Augmentin, but while taking it, the child began to have digestive disorders. Now we use Solutab Flemoclav. I recently found out that this medicine is even safer and more effective. My son had no side effects when taking it.

Valeria, 60 years old, Smolensk

A couple of months ago, my granddaughter fell ill with bacterial tonsillitis. The doctor advised her to give Flemoclav. The medicine helped quickly. After just 2 days, our little Svetochka was already playing with toys and having a hearty dinner. They were given taking into account the requirements of the instructions and according to the schedule specified by the doctor. Within weeks, the disease was completely defeated.

Doctors' opinions and patient reviews

Evgeniy, therapist, 47 years old, Novosibirsk: “Antibiotics are analogues. Both are effective in the treatment of infectious and inflammatory diseases caused by pathogenic microflora sensitive to amoxicillin. Augmentin has a longer history of use and is therefore well studied. But compared to Flemoklav it gives more side effects. Solutab is better tolerated by patients. Suitable for both adults and children. Not all colleagues agree on such drug assessments.”

Svetlana, pediatrician, 57 years old, Nizhny Novgorod: “I prescribe Flemoklav for children with acute sinusitis. Symptoms disappear quickly, and there are few complaints about side effects. Augmentin is not so good for the child's body, but it is cheaper. The most common side effect is diarrhea. I recommend taking probiotics. When choosing a medicine, I take into account various factors, including the individual characteristics of the patient’s body.”

Tatyana, 37 years old, Vladivostok: “In the cold season, sore throat often occurs, which is accompanied by high fever. Treatment is not complete without antibiotics. I often take Augmentin. Recommended by the doctor. I take 3 tablets a day. Treatment lasts about a week. Sometimes there are side effects such as dizziness and nausea. After completion of treatment, all unpleasant symptoms disappear.

I once told the doctor about this. She recommended an analogue - Flemoclav Solutab. I bought this drug for another sore throat. It helps as well as Augmentin, there were no side effects. But it costs more."

Alexandra, 26 years old, Penza: “The child is 4 years old. Gets a cold often. Previously, the doctor prescribed Augmentin, but because of this drug, my son developed diarrhea. Then the doctor recommended another antibiotic - Flemoclav Solutab. This medicine is much better for my son. There were no side effects. Convenient form of release - I simply dissolve the tablet in water and give the suspension to the child. A package of 20 tablets is enough for 1 course. Flemoklav is more expensive than Augmentin, but it’s better for our son, so we don’t mind the money.”

Augmentin and Flemoclav Solutab are broad-spectrum beta-lactam antibiotics identical in composition. They are prescribed for the same diseases, but have several differences that must be taken into account when purchasing a medicine.

Doctors' reviews of Augmentin or Flemoklav Solutab

Semyon, therapist, 44 years old, Astrakhan

The drugs Flecoclave and Augmentin are analogues of each other. However, the first medication is less likely to cause adverse reactions and is more suitable for treating children and adult patients. Despite the same active ingredients, these medications are manufactured by different companies. Before taking them, you should definitely consult a doctor, otherwise you can further aggravate the course of the disease.

Vasily, pediatrician, 40 years old, Ryazan

Most often, I prescribe Flemoklav Solutab to children. If this drug is not available in the pharmacy, you can buy Augmentin powder to prepare syrup. It is not advisable to purchase tablets, because they have an irritating effect on children's intestines and stomach.

Which is better, Flemoklav Solutab or Augmentin

Both drugs are highly effective and have a wide spectrum of action, so no doctor can tell which drug is better or worse. When prescribing, the doctor takes into account several factors, including the patient’s medical history. If the patient expresses a wish regarding the form of administration, then this is also taken into account when choosing an antibiotic.

It should be remembered that the choice of antibacterial drug is the prerogative of the doctor. The patient must follow the specialist's recommendations.

Similarities

These antibiotics are largely similar to each other - active ingredients, indications and contraindications. Both products are available in the form of tablets for oral administration. Both drugs can be purchased with a doctor's prescription.

Augmentin or Flemoklav Solutab: what is the difference?

To find out how these drugs differ, you should familiarize yourself in more detail with their chemical composition and other characteristics: indications and contraindications for use, as well as side effects of treatment.

Compound

The active ingredients of both drugs are an antibiotic from the group of beta-lactams, amoxicillin and clavulanic acid, which prevents its destruction. The amount of active components may vary in different dosage options and dosage forms.

Mechanism of action

Amoxicillin is an antibiotic with a wide spectrum of antimicrobial action. It is active against most common pathogens of infectious inflammation. It has a bactericidal effect on pathogenic microorganisms, that is, it destroys them.

Clavulanic acid is an inhibitor (substances that slow down the chemical reaction) of the enzyme that breaks down amoxicillin. Many pathogenic bacteria produce beta-lactamase, which makes the medicine ineffective, and clavulanic acid protects the antibiotic from destruction.

It must be said that there is a difference between the drugs in the absorption and distribution of the active substance. The soluble dosage form improves the absorption of the drug in the digestive tract, so Flemoklav Solutab is better absorbed. Augmentin, tablets of which dissolve only in the intestines, more often causes negative side reactions from the digestive system.

Indications

Augmentin and Flemoklav Solutab are prescribed for the same infections caused by bacteria sensitive to these antibiotics:

upper respiratory tract (pharynx, tonsils);
ENT organs (middle ear, paranasal sinuses);
lower respiratory tract (bronchi, lungs);
kidneys, urinary tract;
genitals;
soft tissues.

Augmentin is also indicated for bacterial inflammation of bones, joints, and blood poisoning.

Contraindications

intolerance to the drug and other antibiotics from the beta-lactam group;
age under 2 years;
liver dysfunction caused by amoxicillin;
infectious diseases of the lymphatic system.

intolerance to beta-lactams, clavulanic acid and other components of the drug;
liver and kidney dysfunction;
phenylketonuria is a hereditary disorder of amino acid metabolism;
children up to 3 months (for suspension) or up to 12 years (for tablets).

Side effects

Common to Augmentin and Flemoklav:

nausea, vomiting;
diarrhea;
headache;
allergic reactions;
candidiasis of the mucous membranes (thrush).

Release forms and price

Flemoclav Solutab is a dispersible (soluble) tablet with different dosages of active ingredients:

125+31.25 mg, 20 pieces – 293 rubles;
250+62.5 mg, 20 pcs. – 425 rub.;
500+125 mg, 20 pcs. – 403 rub.;
875+125 mg, 14 pieces – 445 rubles.

Augmentin is available in two dosage forms:

coated tablets, 375 mg, 20 pcs. – 246 rubles;

625 mg, 14 pieces – 376 rubles;
875 mg, 14 pieces – 364 rubles;
1000 mg, 28 pcs. – 653 rub.;

suspension 156 mg/5 ml, 100 ml – 135 rubles;
200 mg/5 ml, 70 ml – 144 rubles;
400 mg/5 ml – 250 rubles;
600 mg/5 ml – 454 rub.

Brief characteristics of Flemoclav Solutab

The antibacterial drug contains 2 active components - amoxicillin and clavulanic acid. The drug has an effect on many gram-positive and gram-negative bacteria. Release form: tablets.

Indications for use of Flemoclav Solutab:

infectious and inflammatory diseases of the respiratory system, ENT organs, bones and joints, skin and soft tissues;
diseases of the female genital organs caused by microorganisms sensitive to amoxicillin;
infections and inflammations of the genitourinary system.

The drug is not prescribed for mononucleosis, lymphocytic leukemia, liver disorders associated with taking an antibiotic, observed previously. Flemoklav is contraindicated in case of intolerance to the components included in its composition and sensitivity to penicillins and cephalosporins. It is not recommended to use the medicine to treat children under 12 years of age. Pregnancy is not a contraindication to the use of antibiotics, but the prescription can only be made by a doctor who monitors the progress of treatment.

Flemoclav has many side effects.

The digestive, cardiovascular, nervous, genitourinary and hematopoietic systems may react negatively to taking pills. Sometimes patients complain of developing allergies. If unpleasant symptoms appear, you should stop taking the medicine and consult a doctor.

The digestive, cardiovascular, nervous, genitourinary and hematopoietic systems may react negatively to taking Flemoclav Solutab.

Modern drugs based on amoxicillin - effectiveness or commercial move

Both medicines, Augmentin and Flemoklav Solutab, contain the main active ingredient amoxicillin. This is a well-known semi-synthetic antibacterial substance of the penicillin class, which has high availability when taken orally, good absorption and low toxicity.

Amoxicillin has a bactericidal effect. By breaking down the enzymes necessary to build the cell walls of the microorganism, it causes its death. There are a lot of bacteria that are sensitive to the action of antibiotics. These include gram-positive staphylococci and streptococci, and gram-negative Escherichia coli, Shigella, Pseudomonas aeruginosa, Salmonella and others. Amoxicillin is also effective against all microorganisms sensitive to penicillin.

What makes Amoxicillin a popular drug is its low cost and the ability to prescribe it to patients of all ages. The price of the product in the pharmacy is from 70 rubles for a package of 16 pieces. So why are sometimes more expensive medications prescribed instead, such as Augmentin or Flemoclav, which cost from 200 rubles per pack?

The thing is that amoxicillin is not as universal as it seems at first glance. Some bacteria have already developed their immunity to the antibiotic. They secrete a special protein - beta-lactamase - that destroys the structure of the product and significantly reduces its effectiveness. To neutralize protective antibodies of bacteria, clavulanic acid is prescribed in addition to amoxicillin in the treatment of certain infections. It destroys protein bonds and protects the main component from decay.

The addition of potassium clavulanate to the composition distinguishes the preparations “Flemoklav Solutab” and “Flemoxin Solutab”.

Separate use of these two components is not always convenient or justified. Therefore, pharmacists combined them into one drug, selecting optimal universal dosages for joint use. It now becomes clear that in some cases the use of combination drugs is a necessary condition for fighting the infection.

But doubts arise again: Augmentin or Flemoklav Solutab, which should you choose for treatment? The second one costs a little more, is it more effective? Let's look at it in detail.

Similarities and differences between drugs

Both products contain two active ingredients: amoxicillin and potassium clavulanate. The proportions of component content are approximately identical for the powder form of Augmentin and the tablet form of Flemoklav. Augmentin in tablet form contains the same dose of clavulanic acid (125 mg) in different dosages of amoxicillin (250, 500, 875 mg).

Based on these data, it can be assumed that the Augmentin composition suppresses the action of beta-lactamases faster and more effectively and allows reducing the concentration of amoxicillin, reducing its harm to the body. However, no formal laboratory studies have been conducted on this topic. But we can say with confidence that lower concentrations of potassium clavunate in Flemoklav will reduce the likelihood of an allergic reaction to this component.

Release form

Augmentin, produced in Great Britain, is available in powder form for making a suspension yourself or in the form of oval tablets with a break mark in the middle, coated for easy passage through the digestive tract. Dosage of bulk substance 125, 250, 400 mg, tablets - 250, 500, 875 mg.

Flemoklav Solutab is a Dutch drug that is available only in tablet form. The note “Solutab” means that the pills are soluble. If desired, they can be diluted with water. This form is universal and replaces solutions or suspensions. Just like Augmentin, it is produced in various dosages from 125 to 875 mg, which makes it convenient to select the drug taking into account the patient’s age and the severity of the infection.

Thus, it is impossible to say unambiguously which form is more convenient for use.

Indications for use

The paper instructions for the drug "Augmentin" have a more detailed list of uses. But in general, the products are identical in indications.

This type of antibiotic is prescribed:

for the treatment of ENT organs;
in the treatment of inflammatory processes of the lower respiratory tract;
with bacterial damage to the skin, soft tissues, bones and joints;
for the treatment of certain inflammations of the genitourinary system, sanitation of the birth canal, in the postoperative period;
in the treatment of maxillofacial infections.

Most often prescribed for the treatment of sinusitis, otitis media, tonsillitis, tonsillitis, bronchitis, pneumonia and cystitis.

Both drugs are well tolerated and are quickly absorbed from the gastrointestinal tract. The antibacterial component is excreted by the kidneys, clavulanic acid is removed from the body with urine, feces and exhaled air.

The complex of active substances retains its effect for up to 6 hours, then the effectiveness gradually decreases. The drugs cross the placental barrier and are found in a woman’s breast milk.

Flemoklav Solutab

Broad-spectrum penicillin antibiotic with beta-lactamase inhibitor.

The main active substance is Amoxiciln + Clavulanic acid. Excipients: microcrystalline cellulose, crospovidone, vanillin, apricot flavor, saccharin, magnesium stearate.

Release form: dispersible tablets

Indications for: infections of the upper and lower respiratory tract, ENT organs, gynecological and obstetric infections, infections of bones and joints, infections of the dermis and soft tissues, infections of the kidneys and urinary tract.

Contraindicated in: renal and liver failure, lymphocytic leukemia, mononucleosis, children under 12 years of age, increased sensitivity to the components of the drug.

Side effects affect the systems: very rarely on the coagulation system, rarely on the cardiovascular, nervous and hematopoietic systems. Often from the liver and allergic reactions, not often from the genitourinary system.

Stored for 3 years in a dark place out of reach of children, and 2 years for tablets with a dosage of 875/125 mg.

For complete information, we recommend reading the article:

Choice of product

When choosing a prescribed medication, the doctor takes into account the patient’s medical history and is interested in the preferred form of administration. Since in comparing these two drugs the main difference is in it.

Thus, if there are no contraindications to taking a particular drug and the method of application does not matter much, patients usually choose a drug based on its cost and availability in pharmacies.

Both drugs are available in most locations in varying dosages. At the same time, the price for Augmentin is slightly lower than for Flemoclav Solutab.

Analogs

Pharmacy shelves offer many such drugs. The most affordable one has the simple trade name “Amoxicillin + clavulanic acid” and costs about 70 rubles per pack.

Their prices differ significantly. So, Klamox can be bought for 63 rubles, and Arlet from 368 rubles.

Reviews and recommendations from experts

Preparations containing amoxicillin and clavulanic acid have proven themselves to be effective for the treatment of various infections of bacterial origin. Each doctor has his own favorite brand name, which he prescribes most often.

This composition has practically no side effects and is well tolerated even by children of the first year of life and has positive reviews from parents of young patients.

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