What to give preference – Flemoxin or Amoxicillin

Doctors often prescribe Azithromycin or Flemoxin Solutab to patients with diseases caused by pathogenic bacteria. These antibiotics belong to different groups and differ greatly in composition, so it is not recommended to independently choose which medication to treat.


Doctors often prescribe Azithromycin or Flemoxin Solutab to patients with diseases caused by pathogenic bacteria.

Children's analogs of Flemoxin Solutaba

The range of antibiotics for children is quite large, but any medicine can only be prescribed by a pediatrician.
Flemoxin Solutab is not available in granules, so if necessary, the doctor can prescribe a structural analogue or a drug from a different group, but with an identical therapeutic effect.

Children from 6 years of age can take antibiotics in the form of tablets, and only from 12 years of age capsules are allowed for use.

Antibacterial drugs in the form of injection ampoules are suitable for children of all ages, but such drugs are administered only in a hospital.

In practice, the following drugs are most often used:

  • Macropen – from 276 rub. Antibiotic from the macrolide group. Has a pronounced antibacterial effect. It is often used when a child is intolerant to drugs of the penicillin group. The active component of Macropen is clarithromycin.
  • Klacid – from 371 rub. An antibiotic based on clarithromycin, a macrolide. For children it is available in a 200 ml bottle. Currently, the drug is considered one of the most effective and safe, often prescribed in pediatrics for the treatment of otitis media, bronchitis, pneumonia and other ENT diseases.
  • Augmentin – from 480 rub. An analogue of Flemoxy Solutab, but in addition to amoxicillin it contains clavulanic acid, which enhances the effect of the antibiotic and helps cope with bacteria that are resistant to penicillin. Children are prescribed Augmentin suspension, which has good reviews and is often used in pediatrics.
  • Cefuroxime – from 1250 rub. A drug from the cephalosporin group. Prescribed to children when the disease is advanced or penicillin antibiotics have not shown effectiveness. For children, only an injection solution can be used, which is administered in a hospital setting under the supervision of a physician.
  • Amoxiclav – from 395 rub. An antibacterial drug from the penicillin group with a beta-lactamase inhibitor. For children it is provided in the form of a suspension for oral administration. In addition to amoxicillin trihydrate, the drug contains clavulanic acid. Available in a 200 ml bottle containing granules for preparing a suspension.

In addition to the above antibiotics used in pediatrics, there are others that are no less effective. However, the choice of drug always remains with the attending physician.

Imported substitutes

Imported drugs often displace domestic ones, but such drugs have a higher cost and undergo several stages of purification, which makes them less toxic to human health.

All foreign-made analogues have a higher cost.

Foreign antibiotics include not only those that contain amoxicillin, but also combination agents. Most often, the composition of combination drugs includes clavulanic acid, which increases the effect of the antibiotic.

The most common include:

  • Flemoxin Solutab - contains two active substances - amoxicillin and clavulanic acid. It belongs to modern broad-spectrum antibiotics, is well tolerated, and can be prescribed to children and even pregnant women. The drug is a product of Astellas Pharma Europe B (Netherlands), it has a high cost, so it cannot be classified as a cheap antibiotic.
  • Amoxiclav is an antibiotic from Austria, Slovenia and Switzerland. It is a semi-synthetic combination drug because it also contains amoxicillin and clavulanic acid. The drug can be purchased in several pharmacological forms. It is not a cheap drug, since its price exceeds 500 rubles.

Features of application

Before using the drug, read the sections of the instructions for use about contraindications, possible side effects and other important information

Side effects Flemoxin solutab 500\1000 mg

Instructions for use warn of the possibility of side effects of the drug Flemoxin Solutab:

  • Central nervous system: excessive arousal, behavior changes, depression, anxiety, epileptic seizures, insomnia, headache, ataxia, confusion, dizziness, peripheral neuropathy.
  • Digestive system: rarely - glossitis, change in taste, stomatitis, attacks of nausea, dysbacteriosis, diarrhea, vomiting; in some cases - cholestatic jaundice, increased activity of liver transaminases (moderate), hemorrhagic and pseudomembranous colitis, cytolytic hepatitis in the acute stage, hepatic cholestasis.
  • Hematopoietic system: thrombocytopenia, leukopenia, hemolytic anemia, neutropenia, eosinophilia, thrombocytopenic purpura, agranulocytosis.
  • Urinary system: crystalluria, development of interstitial nephritis.
  • Allergic reactions: skin manifestations, mainly in the form of maculopapular rash, skin hyperemia, urticaria, arthralgia, erythematous rashes, erythema multiforme exudative, rhinitis, exfoliative dermatitis, conjunctivitis, eosinophilia, fever, reactions resembling serum sickness, allergic vasculitis , toxic epidermal necrolysis, acute exanthematous generalized pustulosis; in some cases - angioedema, anaphylactic shock.
  • Other: vaginal candidomycosis, difficulty breathing, superinfection (especially in patients with reduced body resistance or chronic pathologies).

Contraindications

The use of Flemoxin Solutab is contraindicated for the following diseases or conditions:

  • hypersensitivity to the components of the drug;
  • hypersensitivity to other beta-lactam antibiotics, incl. to other penicillins, cephalosporins, carbapenems.

The drug should be used with caution in cases of polyvalent hypersensitivity to xenobiotics, infectious mononucleosis, lymphocytic leukemia, a history of gastrointestinal diseases (especially with colitis associated with the use of antibiotics), renal failure, during pregnancy and lactation, allergic reactions (including in the anamnesis)

Overdose

Symptoms of overdose are dysfunction of the gastrointestinal tract (accompanied by diarrhea, nausea and vomiting, water and electrolyte imbalance).

It is recommended to lavage the stomach, prescribe saline laxatives, enterosorbents, and take measures aimed at correcting the balance of water and electrolytes.

Pharmacokinetics

Suction

Amoxicillin is taken orally, 93 percent of the drug is quickly absorbed after administration, and is acid resistant. The absorption of the drug does not change under the influence of food intake. The maximum concentration of amoxicillin is observed in plasma after an hour or two. Taking amoxicillin at a dose of 500 mg guarantees the maximum concentration of the drug in the blood plasma after two hours. Increasing or decreasing the dose leads to a corresponding decrease or increase in the concentration of the drug in the blood plasma.

Distribution

Approximately 20 percent of the active substance binds to plasma proteins. Amoxicillin has the ability to actively penetrate bone tissue, mucous membranes, sputum, and intraocular fluid in effective therapeutic concentrations. The concentration of the drug in bile is two to four times higher than the concentration of the drug in plasma. In the amniotic fluid and umbilical cord vessels, the concentration of the drug is approximately 25-30% of the concentration of the drug in the plasma of a pregnant woman. Amoxicillin almost does not penetrate the blood-brain barrier, but with inflammation of the meninges, the level of the drug in the cerebrospinal fluid is equal to 20% of the level in the blood plasma.

Metabolism

Amoxicillin is partially metabolized in the liver; most of its metabolites do not have microbiological activity.

Removal

Amoxicillin is excreted mainly by the kidneys, 50–70% of the dose taken (250 mg) is excreted unchanged in the urine. 10–20% of Amoxicillin is metabolized. The b-lactam ring is metabolized to penicillic acid, which is excreted in the urine.

A minimal amount is excreted in bile.

The pharmacokinetics of Amoxicillin in children over 2 years of age is almost the same as in adults. In children aged 1–2 years, the absorption of Amoxicillin is slightly faster.

In newborns, Amoxicillin is excreted more slowly than in adults. Their half-life is 3.7–4 hours.

Indications and dosages

Flemoxin Solutab tablets are highly effective in the treatment of the following diseases:

  • complicated sinusitis;
  • sinusitis;
  • tonsillitis;
  • pharyngitis;
  • otitis;
  • bronchitis;
  • tracheitis;
  • pneumonia.

Indications for prescribing the drug are other infections affecting internal organs and systems. The spectrum of antibiotic use is quite wide, but in any case it must be prescribed by a doctor individually for each patient.

The dosage of the medicine and the duration of administration are determined by the doctor and depend on the final diagnosis, the age of the patient, and the characteristics of the body’s ego.

According to the instructions, for children under 10 years of age the daily dose should not exceed 750 mg. Adults can take 500 mg three times a day.

The treatment course ranges from 5 to 14 days. The drug dissolves well in water - it turns into a suspension, which makes it easy for children to take.

For diseases of the ENT organs, such as tonsillitis, pharyngitis, otitis media or sinusitis, it is recommended to take Flemoxin Solutab tablets for 10 days.

If after 3 days of taking there is no result from treatment, the patient’s condition has worsened, and the disease itself is progressing, you should consult a doctor who can select a similar drug from another group.

In such cases, antibiotics of other groups will be prescribed - macrolides, cephalosporins.

Penicillin group – amoxicillin

An antibiotic such as Amoxicillin has the following indications for use:

  • angina;
  • chronic tonsillitis during exacerbation;
  • acute manifestation of otitis media;
  • sinusitis;
  • bronchitis during relapse;
  • scarlet fever;
  • infectious skin lesions;
  • cystitis, pyelonephritis and other infections (especially those occurring in acute form).

This substance is low-toxic and has a wide spectrum of action. One of the most common negative reactions from the body is allergies.

As the instructions say, the main contraindication is individual intolerance to any components.

If we compare Ciprofloxacin and Amoxicillin, as the two most prominent representatives of different groups of antibiotics, then the latter more often lead to allergic reactions. If an allergic reaction occurs after taking the drug, you need to stop using the antibiotic and go to the doctor as soon as possible.

Amoxicillin is one of the few drugs that doctors can prescribe to pregnant women, as well as to children of any age (even newborns).

Please note that all drugs that contain amoxicillin and/or clavulanate (clavulanic acid) significantly reduce the effectiveness of contraceptive drugs (for example, Amoxiclav, Ampicillin, Amoxicillin, Flemoxin, etc.).

Pharmacological action of the drug

Flemoxin Solutab is a semi-synthetic antibiotic based on amoxicillin. Copes well with a number of pathogenic microorganisms with bacterial flora.

It has a pronounced antimicrobial effect and is highly effective in the fight against staphylococcal, streptococcal, gonococcal, and pneumococcal infections. Not used for diseases caused by shigella, salmonella, and also has no effect on viruses and fungi.

The mechanism of action of the drug is to disrupt the structure of various bacteria, destroy their cells with further death.

Taking an antibiotic not only stops the growth of pathogenic microorganisms, but also prevents them from penetrating deep into the epithelium.

The active component of the drug, amoxicillin, is quickly absorbed into the bloodstream, penetrates into the soft tissues and intraocular fluid. It shows its effectiveness within 1 – 2 hours after administration.

Flemoxin Solutab, as well as some of its analogues, have undergone a high degree of purification, which minimizes the risk of developing side effects after administration. The medicine is often used in pediatrics because it has low toxicity.

General description of drugs

Amoxicillin is a semi-synthetic antibiotic and is characterized by strong bactericidal properties against gram-positive microorganisms.
This drug has a destructive effect on the cell membrane of harmful bacteria. It is prescribed for the treatment of pathologies of the respiratory organs, as well as in urological and sometimes gynecological practice. Flemoxin Solutab is an analogue of Amoxicillin, which belongs to the medicinal group of semisynthetic antibiotics. Flemoxin is characterized by a fairly broad spectrum of action; both gram-positive and many gram-negative bacteria are sensitive to this drug. The active substance is Amoxicillin. In the human body, the antibiotic disrupts the membrane of pathogenic microorganisms at the cellular level. Shows low activity against Staphylococcus and Helicobacter.

Despite the fact that the active ingredient in both drugs is the same, you must obtain a doctor’s permission before replacing them.

Flemoxin or amoxicillin?

Amoxicillin is a completely structural analogue of flemoxin, because their active ingredients are completely the same. According to research, there is information that flemoxin solutab has faster absorption in the gastrointestinal tract, and amoxicillin is sometimes destroyed without delivering all the substance to its intended purpose. This affects antibacterial activity. The conclusion is that flemoxin is more effective.

Flemoxin has fewer side effects and is better accepted by the gastric mucosa, and this is important for patients with gastrointestinal problems. In pediatrics, flemoxin is more often used, considering it a higher-quality drug with a maximum degree of purification

Flemoxin solutab is widely used for otitis media, which often accompanies respiratory viral infections in children.

In pediatrics, flemoxin is more often used, considering it a higher-quality drug with the maximum degree of purification. Flemoxin solutab is widely used for otitis media, which often accompanies respiratory viral infections in children.

Regardless of the benefits of any drug, only a doctor should decide which is best. The patient’s task is to inform the doctor in a timely manner about the negative effects of the drug, of course, whether such will occur.

We recommend that you read Amoxicillin: analogues and reviews.

Don’t overpay in vain, comparison of Flemoxin and Amoxicillin

Amoxiclav or Tsifran: which is better?

  • Amoxiclav is a combined antibacterial drug, available not only in the form of tablets, but also as a suspension. It contains clavulanic acid, so treatment with this drug is easier to tolerate by the patient’s body.
  • However, Cifran is the only oral drug with antipseudomonas activity. Therefore, it is more effective in treating acute forms of infectious diseases and advanced bacterial infections.
  • We also note that Cifran demonstrates high effectiveness for the treatment of elderly patients.

If you perform a comparative description of another analogue of Tsifran in terms of therapeutic effect, you can come to the following conclusions: Tsiprolet is available in the form of tablets, injection solution and eye drops.

Both drugs are antibiotics used to treat various types of infections, however, Tsiprolet belongs to the second generation antibiotics and is better tolerated by patients with gastrointestinal problems.

This drug is prescribed to combat infectious and bacterial diseases.

Cifran is best taken by those patients who suffer from gastrointestinal diseases. After all, Cifran ST has virtually no effect on the microflora in the human intestine, thereby not provoking bacterial candidiasis and vaginal vaginosis in representatives of the fairer sex of humanity.

Dysbacteriosis does not develop while taking it, but the effectiveness of treatment is quite high. The effect lasts for 12 hours after taking the tablet.

Cifran and Ciprofloxacin have exactly the same effect on the human body. These drugs are interchangeable, that is, if it is impossible to get one of them, it can be replaced with an analogue. Both drugs are highly effective in combating many diseases. For example, they are used in the treatment of chronic sinusitis or sinusitis.

We invite you to familiarize yourself with the correct and incorrect dental occlusion, types, causes of development, physiological occlusion

Both Cifran and Ciprofloxacin are used in the treatment of adult patients. They are not prescribed for children under 6 years of age; the course of treatment is selected individually for each specific patient and can be adjusted during the admission process.

Suprax or Flemoxin?

The drugs belong to different pharmacological groups. Flemoxin solutab is a penicillin, suprax is a third generation cephalosporin. These drugs are analogues only in terms of therapeutic effect, because Suprax contains a completely different active ingredient - cefixime (in the form of trihydrate).

Suprax is available not only in capsules, but also in granules, which Flemoxin does not have. In pediatrics, suprax is used from 6 months, and flemoxin from only three months.

In terms of its effect on the body, Suprax is stronger, like all cephalosporins. Penicillins belong to the weakest group among all antibacterial agents; in our case, flemoxin belongs to them.

Suprax has more side effects, so its toxicity is higher

The instructions for Suprax warn that elderly patients should use this drug with extreme caution.

Conclusion

Antibacterial agents protect various infectious processes. Some are weaker, others are sick and powerful. Patients do not always realize that the choice of antibiotic is an individual matter. You don’t need to take the same remedy that helped your neighbor. In your case, it may simply be useless. Only the antibiotic that is sensitive to the causative agent of the disease is beneficial.

In most cases, treatment therapy begins with penicillins. It is not recommended to “load” the body with more powerful drugs, because uncomplicated bacterial infections are quite amenable to drugs such as flemoxin solutab.

If flemoxin does not meet any criteria, be sure to inform your doctor about this; a replacement can always be found, but the main thing is not to do it yourself.

In order not to be deceived by the price, always calculate the course of treatment (one drug is taken three times a day, and you will need more tablets, while the other is taken once).

Therefore, it is not advisable to compare the price only “by box”. Everywhere there may be different doses and number of tablets. Be careful when buying analogues to really choose a cheap and effective product! Good health!

Amoxiclav or Tsifran: which is better?

It is worth understanding the following question: Amoxiclav or Cifran, which is better? Comparative characteristics of the therapeutic effect of Amoxiclav and Tsifran indicate that:

  • Amoxiclav is a combined antibacterial drug, available not only in the form of tablets, but also as a suspension. It contains clavulanic acid, so treatment with this drug is easier to tolerate by the patient’s body.
  • However, Cifran is the only oral drug with antipseudomonas activity. Therefore, it is more effective in treating acute forms of infectious diseases and advanced bacterial infections.
  • We also note that Cifran demonstrates high effectiveness for the treatment of elderly patients.

If you perform a comparative description of another analogue of Tsifran in terms of therapeutic effect, you can come to the following conclusions: Tsiprolet is available in the form of tablets, injection solution and eye drops.

Both drugs are antibiotics used to treat various types of infections, however, Tsiprolet belongs to the second generation antibiotics and is better tolerated by patients with gastrointestinal problems.

This drug is prescribed to combat infectious and bacterial diseases.

It is worth noting

Cifran is best taken by those patients who suffer from gastrointestinal diseases. After all, Cifran ST has virtually no effect on the microflora in the human intestine, thereby not provoking bacterial candidiasis and vaginal vaginosis in representatives of the fairer sex of humanity.

Dysbacteriosis does not develop while taking it, but the effectiveness of treatment is quite high. The effect lasts for 12 hours after taking the tablet.

Cifran and Ciprofloxacin have exactly the same effect on the human body. These drugs are interchangeable, that is, if it is impossible to get one of them, it can be replaced with an analogue. Both drugs are highly effective in combating many diseases. For example, they are used in the treatment of chronic sinusitis or sinusitis.

Both Cifran and Ciprofloxacin are used in the treatment of adult patients. They are not prescribed for children under 6 years of age; the course of treatment is selected individually for each specific patient and can be adjusted during the admission process.

Instructions

Composition, release form, price

The main active ingredient of flemoxin is amoxicillin trihydrate, it is offered only in tablet form, 125, 250, 500 mg, as well as 1 gram.

The cost of the drug varies depending on the dosage, and ranges from 300 to 500 rubles.

When is flemoxin solutab prescribed?

The drug will be useful for all infections sensitive to amoxicillin trihydrate. Most often, this antibiotic is used for infections of the respiratory and genitourinary systems, as well as for bacterial lesions of soft tissues, skin, and gastrointestinal tract.

How to take the drug?

Flemoxin is taken regardless of meals. The maximum daily dose for patients starting from the age of ten is 1500 mg, from 3 to 10 years - 700 mg, from 1 to 3 years - 500 mg. The frequency of administration is determined by the doctor, i.e. two or three times a day.

The dosage is also adjusted, so if you have a mild or moderate degree of the disease, it is not necessary to drink the maximum permitted portion of the drug. The duration of treatment depends on the severity of the infection, the minimum period of taking the drugs is 5 days.

Contraindications

Flemoxin is not prescribed in the following cases:

  • lack of sensitivity to the active substance;
  • individual intolerance;
  • pregnancy and lactation;
  • severe liver and kidney diseases;
  • pseudomembranous colitis.

Adverse reactions

Negative reactions can be varied, and they are observed from various organs and systems. The greatest likelihood of such reactions occurring is associated with long-term use of the drug.

According to statistics, skin rash, diarrhea, colitis, nausea, coating on the tongue, and lack of appetite are more common. Other “side effects” are reported less frequently.

In case of intolerance to amoxicillin trihydrate, flemoxin solutab is replaced with analogues, taking into account all the patients’ wishes to choose a cheaper drug. There are enough antibacterial drugs on the pharmaceutical market, so there is no need to put in much effort in finding cheap analogues.

Description of Sumamed

The antibiotic Sumamed is used primarily for respiratory diseases. It is produced in tablet form and in powder form by pharmaceutical companies Pliva Hrvatska and Teva. The active ingredient is azithromycin dihydrate. Dispensed with a doctor's prescription.

Azithromycin is a semisynthetic antibiotic, a representative of azilades. Gives a bacteriostatic effect. Azithromycin is active against microorganisms such as streptococci, staphylococci, Neisseria gonorrhoeae, Mycobacterium avium complex and others.

Sumamed, due to its component, can be used effectively for such common pathologies as tonsillitis, sinusitis, scarlet fever, laryngitis, bronchitis. It can be prescribed not only for respiratory diseases, but also for infections of the genitourinary system, such as gonorrhea, cervicitis, urethritis. Also indicated for ulcers caused by Helicobacter pylori as an auxiliary drug in combination therapy.

Research and effectiveness

Clinical studies using Sumamed for community-acquired pneumonia have established its high effectiveness and relative safety. It has a convenient dosage and does not require long-term use, which reduces the likelihood of side symptoms.

The drug shows high activity against common pathogens of respiratory tract pathologies, including pneumococcus and Haemophilus influenzae. Sumamed can be recommended as the main drug for pneumonia without complications in children.

The most used substance from the group of macrolides is azithromycin due to its effectiveness and safety. It is widely used to treat respiratory tract infections in childhood. Can be used as a single drug or in a combination regimen.

Sources:

  1. "Clinical use of macrolides for pneumonia in children." Krivopustov S.P. 2009.
  2. “The use of the drug Sumamed in the treatment of uncomplicated forms of community-acquired pneumonia in children.” Abaturov A.E. 2011.

Contraindications

Any antibacterial drug has a number of strict restrictions on use. Broad-spectrum antibiotics can be prescribed at a stage when the pathogen has not yet been differentiated to provide quick assistance, but even then it is necessary to exclude contraindications to the use of certain groups of bacteriostatic agents.

In what cases should the antibiotic Sumamed not be used:

  1. intolerance to azithromycin and other macrolides;
  2. hypersensitivity to excipients in the composition;
  3. phenylketonuria;
  4. severe liver disease;
  5. in combination with ergotamine;
  6. up to 3 years.

There are also relative restrictions under which Sumamed can be prescribed, but with caution. This applies to any diseases of the urinary and hepatobiliary systems. In old age, when there are disorders of the heart and blood vessels, additional tests are also required to determine the possibility of taking it.

During pregnancy, it is permissible to take it when the benefit outweighs the risk to the unborn child. During lactation, you need to stop breastfeeding for a while.

For chlamydia in a pregnant woman, azithromycin is recommended by WHO as the drug of choice.

Side symptoms

Common side effects from taking Sumamed include diarrhea, headache, and nausea.

Rare unpleasant symptoms from the use of azithromycin include:

  1. thrush of the oral cavity and genitals;
  2. rhinitis, pharyngitis, pneumonia;
  3. hypersensitivity reactions, allergic manifestations;
  4. insomnia, nervousness, changes in taste sensations;
  5. convulsions, hallucinations, delirium, myasthenia gravis;
  6. hearing loss, vertigo, tinnitus;
  7. itching, urticaria, dermatitis, loss of skin moisture, increased sweating, erythema;
  8. chest pain, dysuria, fever, facial swelling, asthenia, edema, malaise.

With a long course, laboratory changes are noted. When you need to take Sumamed for longer than the recommended time, you should monitor your kidney condition and take blood and urine tests.

Features of application

For children, the dose is selected according to weight:

  1. 18-30 kg – 250 mg;
  2. 31-44 – 375 mg;
  3. from 45 kg – adult dosages.

Taken after meals for 1-2 hours. The tablet can be drunk whole or dissolved in water. The suspension should be mixed well before swallowing.

Children under 3 years of age should use Sumamed in powder, from which a suspension is prepared.

Temporary hearing loss may occur if the recommended dose is increased. An overdose is accompanied by nausea and diarrhea.

Features of treatment with Sumamed:

  1. If you miss a pill, you should take it as soon as possible, and drink the next dose after 24 hours;
  2. You need to take the medicine one hour before or 2 hours after taking antacids;
  3. if symptoms such as jaundice, increasing asthenia, bleeding, darkening of urine appear, you should go to the doctor as soon as possible to assess the condition of the liver;
  4. should not be used longer than indicated in the instructions; the pharmacokinetics of the drug allows it to be taken in a short course with a simple dosage regimen without compromising its effectiveness;
  5. if you take the medicine for a long time, there is a risk of diarrhea and colitis;
  6. with myasthenia gravis, the medicine can provoke an exacerbation.

When performing complex actions and driving vehicles, you must be careful, as there is a possibility of developing adverse reactions that affect the senses, concentration and reaction speed.

Who is it suitable for?

The instructions indicate that Sumamed can be prescribed for infections of the respiratory system, skin, urinary and reproductive systems, as well as for erythema migrans.

A doctor should prescribe an antibiotic after examination and evaluation of tests. Long-term use of Sumamed without identifying the pathogen is unacceptable. It will not help when the pathogen is not sensitive to azithromycin. In this case, taking the drug will only worsen the condition.

Side effects caused by taking Flemoxin:

  • digestive and eating disorders, nausea, vomiting, disbacteriosis, cholestatic jaundice, hepatic cholestasis, acute cytolytic hepatitis, stomatitis, colitis (hemorrhagic, pseudomembranous, etc.);
  • complications from the genitourinary system, for example, interstitial nephritis, crystalluria;
  • diseases of the circulatory and hematopoietic systems - leukopenia, neutropenia, thrombocytopenic purpura, eosinophilia, thrombocytopenia, agranulocytosis, hemolytic anemia;
  • neuroses, depression, uneven overexcitation, exhaustion, insomnia, disorientation, migraines, convulsions;
  • allergic reactions of the skin and mucous membranes, up to Stevens-Johnson syndrome, fever, anaphylactic shock and angioedema.

Dosage regimen for sinusitis

This disease is an inflammation of the air-filled cavities connected to the nose. Symptoms: chills, fever, mucus and purulent discharge, pressure in the bridge of the nose, headache when bending or clenching the teeth. If left untreated, this disease can become chronic and cause vision problems, otitis, meningitis, periostitis, systemic inflammation of the body (sepsis).

The disease can be caused by bacteria, viruses, fungi, and allergic reactions. The presence of pus highly likely indicates a microbial source of infection. It is in the case of a bacterial infection that the antibiotic is extremely effective. If the disease is caused by fungi, its use is contraindicated, and it has no effect on viruses. The instructions for use advise taking 2000–3000 milligrams of the medicine in two servings. The allergic form of sinusitis, as well as sometimes the viral form, go away on their own.

Analogs

The drug Flemoxin Solutab has a sufficient number of analogues that can act as its applicant. The list of analogues includes all drugs containing Amoxicillin.

The drug Amoxiclav has a combined effect on the body and is used to eliminate infectious processes accompanied by inflammation. The advantage of this composition is the variety of release forms - the medication is produced in the form of a powder for the preparation of a suspension, oral tablets and powder for injection. The drug is well tolerated and can be used in pediatric practice in separate forms.

Augmentin is considered as the most popular analogue, which is a substitute for flemoxin. The composition is designed specifically to eliminate infectious processes and subsequent inflammatory processes in the human body.

The drug Amoxicillin is also a popular analogue to the drug Flemoxin Solutab. The drug is used to eliminate pathologies of the gastrointestinal tract, ENT organs and diseases of the genitourinary system. The medication has a sufficient number of contraindications for use. Amoxicillin should only be considered as a substitute after consultation with a doctor.

  • Augmentin. This drug has a wide spectrum of action and destroys a large number of bacteria. However, it has more contraindications and side effects, and the price is higher.
  • Amoxiclav. Therapeutically it is also a stronger drug, as it contains clavulanic acid. It can be used for cholecystitis, cholangitis, odontogenic infections, pathologies of bone and connective tissue of infectious origin. It is not recommended for children under three years of age, as allergic manifestations in the form of diathesis are possible.
  • Sumamed, compared to Flemoxin Solutab, contains a different active ingredient and is available in various forms. Prescribed when quick help is needed, for example, with complicated bronchitis.
  • Azithromycin is an analogue of sumamed in terms of active ingredient, but costs several times less.
  • Amoxicillin is much cheaper than flemoxin solutab, but is often destroyed in the gastrointestinal tract, losing its effectiveness.

Flemoxin solutab and Samamed are considered the most acceptable drugs for treating children. However, the pediatrician will decide which drug to choose for the child.

Description of the drugs: Azithromycin and Flemoxin Solutab

Before choosing a specific antibiotic, it is recommended that you read their description.

What are they made of?

The main active component of Azithromycin and Flemoxin is amoxicillin trihydrate.

The active component in the drug "Flemoxin" is supplemented with:

  • crospovidone;
  • microcrystalline cellulose;
  • flavorings;
  • magnesium stearate;
  • vanillin;
  • saccharin;
  • cellulose dispersible.

This addition makes Flemoxin a milder product. But the range of its application is narrowing.

When taken, Flemoxin Solutab enters the gastrointestinal tract. It is not affected by hydrochloric acid. The drug quickly enters the bloodstream. After 2 hours its content becomes highest.

Release form

Azithromycin is supplied to the pharmacy chain in the form of tablets. They have an oval shape. Each tablet has a dividing notch. On the front side, the manufacturer knocks out numbers showing the amount of active substance.

The drug has a bitter taste: it is more difficult for young patients to take. The medicine dissolves easily in the mouth under the influence of saliva. Azithromycin is packaged in a plastic blister and placed (along with instructions) in a cardboard box.

Flemoxin tablets also have notches with numbers. Each notch reflects the amount of active element. It ranges from 125 to 1000 mg. Correspondence:

  • 236-1000;
  • 234-500;
  • 232-250;
  • 231-125.

Flemoxin Solutab also dissolves well. But, unlike Azithromycin, it has a sweet taste. Therefore, parents do not have problems: how to persuade the baby to take medicine.

The product is placed in a plastic blister containing several tablets. It comes with a cardboard box and instructions.

How it affects the body

Both drugs dissolve under the action of gastric juice. But Azithromycin is partially destroyed by hydrochloric acid. Therefore, the effectiveness of the drug decreases.

"Flemoxin" is completely resistant to the action of gastric juice. The drug completely enters the body.

After penetrating into the blood, amoxicillin trihydrate accumulates in the affected organ and destroys harmful bacteria.

Indications for use:

The list of the most common infections for which flemoxin is prescribed includes:

  • respiratory tract;
  • genitourinary system;
  • gastrointestinal organs;
  • skin;
  • and processes of inflammation of soft tissues.

According to the instructions for use, Flemoxin Solutab 1000 mg is prescribed as part of complex therapy. It is not recommended to take the medicine in patients with high sensitivity to amoxicillin and other beta-lacto-drugs of the antibiotic action of the penicillin group.

The list of possible side effects when taking the drug:

  • decreased function of taste buds, vomiting or nausea;
  • dysbacteriosis, expressed by stool disorders;
  • stomatitis and glossitis,
  • liver dysfunction in the form of cholestatic jaundice, hepatic cholestasis, acute cytolytic hepatitis,
  • pseudomembranous and hemorrhagic colitis;
  • interstitial nephritis, crystalluria;
  • leukemia and neutropenia,
  • thrombocytopenic purpura and eosinophilia,
  • thrombocytopenia,
  • agranulocytosis, hemolytic anemia;
  • increased excitability, confusion, anxiety, sleep/wake disturbances, ataxia, depression, dizziness and headaches, epileptic convulsions;
  • various forms of allergy: skin redness, rash, exfoliative-type dermatitis, rhinitis, conjunctivitis, Stevens-Johnson syndrome, fever, arthralgia, eosinophilia, allergic vasculitis, anaphylactic shock, acute generalized exanthematous pustulosis, angioedema.

Directions for use and doses

The dose, frequency of administration and duration of the disease are determined by the doctor depending on the disease.

Adults and children over 10 years of age weighing over 40 kg take from 500 mg to 1000 mg of Amoxicillin twice a day. For sinusitis, pneumonia and other serious infections, take from 500 mg to 1000 mg three times a day. The daily daily dose can be increased to a maximum of 6 g.

Children weighing less than 40 kg take 20 mg to 40 mg per kg body weight daily in three divided doses or 25 mg to 45 mg/kg/day in two divided doses. For children with a high risk of infection caused by resistant Streptococcus pneumonias, the drug is recommended to be prescribed in large doses, that is, 80 mg/kg of the child’s body weight daily in three divided doses or 90 mg/kg of the child’s body weight daily in two divided doses. The maximum daily dose for children is 100 mg/kg body weight.

Boreliosis (Lyme disease): adults and children weighing over 40 kg take from 500 mg to 1000 mg three times a day, and the dose for children weighing less than 40 kg is 50 mg/kg body weight in three divided doses.

To destroy Helicobacter pylori, Amoxicillin is recommended to be used in combination with other medications. Adults take 1000 mg of Amoxicillin twice a day, and children take 50 mg/kg of body weight daily in two doses.

To prevent endocarditis, adults are prescribed 3 g of Amoxicillin 1 hour before surgery and 1.5 g 6 hours after such surgery. Children are prescribed 50 mg/kg body weight before the procedure and 25 mg/kg body weight after it.

Amoxicillin can be used in patients with renal failure. In severe renal failure (creatinine clearance

Characteristics of azithromycin

According to the pharmacological classification, Azithromycin belongs to the azalides . The production of the substance is based on a synthetic method. Azithromycin is not able to completely destroy bacteria; its mechanism of action is aimed at preventing the microorganism from growing and developing normally. Such drugs are also called bacteriostatic antibiotics .

The antibiotic is available in the form of tablets with different dosages: 125 mg, 250 mg, 500 mg, 1000 mg and in powder form for the preparation of a suspension with dosages of 100 mg and 200 mg.

The suspension is intended for internal use for children from six months of age.

A minimum dose of 250 mg is available for use in children over 3 years of age; higher dosages are indicated only for adults.

A dosage of 500 mg is used exclusively for children over sixteen years of age and older generations when treating severe infections.

Indications for use

Infections caused by amoxicillin-sensitive bacteria:

  • infectious diseases of the ENT organs (pharyngitis, otitis media, tonsillitis, sinusitis);
  • infectious diseases of the respiratory system (acute bronchitis of bacterial origin, exacerbation of chronic bronchitis under the influence of bacteria, pneumonia);
  • infectious diseases of the gastrointestinal tract (salmonellosis with sensitivity to the drug);
  • duodenal and gastric ulcers, including those caused by Helicobacter pylori (in combination with other drugs);
  • genitourinary infections;
  • infections of the skin, soft tissues;
  • gonorrhea;
  • Lyme disease;
  • leptospirosis, brucellosis;
  • prevention of infections during surgical interventions in the oral cavity and upper respiratory tract.

Flemoklav or Augmentin

Augmentin is an exact structural analogue of Flemoclav, but at a lower cost (even cheaper analogues are described here). Manufacturer: British pharmaceutical company GlaxoSmithKline.

The medicine has a wide spectrum of action and is used in the treatment of diseases of the ENT organs, skin, bone tissue, etc.

For the convenience of patients and doctors, it is presented in various dosages and dosage forms: tablets, suspensions for oral administration, powders for the preparation of solutions for intramuscular infusions.

When prescribing a suspension for a child, you must ask the doctor to correctly calculate the dose based on body weight and age.

Unlike Flemoklav, Augmentin is not presented in the form of soluble tablets, but this does not affect the therapeutic effect.

Due to the presence of clavulanic acid in the composition, the antibiotic eliminates infections that are insensitive to conventional penicillins.

This allows the use of both Augmentin and Flemokrav as the drug of choice in the empirical treatment of diseases of unknown origin, until the results of bacteriological studies are obtained.

The analogue has the ability to be rapidly absorbed from the gastrointestinal tract and demonstrates pronounced antistreptococcal properties. During treatment, it is possible to develop undesirable reactions from the gastrointestinal tract and liver, as well as allergic manifestations.

During treatment with both antibiotics, there is a high probability of developing dysbiosis, so it is advisable to additionally use medications from the group of probiotics.

Adverse reactions are reversible and disappear 1-2 days after discontinuation of the drug. If side effects develop, especially allergic reactions, you should immediately consult a doctor.

Common features of the drugs

They have an identical main active ingredient – ​​amoxicillin.

Indications for use are identical for both antibiotics; they are prescribed in case of infection in the body:

  • Gastrointestinal tract organs - duodenitis, gastritis, ulcers.
  • Skin and soft tissues.
  • Respiratory system - sore throat, laryngitis, chronic tonsillitis.
  • Genitourinary system.
  • ENT diseases (otitis, sinusitis, rhinitis).

Azithromycin is often used as an analogue of flemoxin solutab.

The use of both the first and second means is possible in childhood and adulthood.

Cheap analogues of Flemoxin

For the convenience of selecting flemoxin analogues, let's make a list of substitutes indicating the price, where it will be clear which drugs are cheaper.

List of cheap analogues

Almost all antibacterial drugs can be considered analogues of flemoxin, because they kill bacterial flora. Among the most popular and cheapest analogues are the following:

  • ospamox (powder, No. 1) – 75 rubles;
  • amosin (500 mg, 10 tablets) – 60 rubles;
  • amoxicar – approximate cost 180 rubles (currently no supply);
  • Grunamox – about 190 rubles (availability in pharmacies needs to be checked);
  • amoxicillin (500 mg, 16 capsules) – 60–100 rubles;
  • ecobol (500 mg, 20 tablets) – 130 rubles;
  • gonoform – 80 rubles.

Flemoxin analogs are cheaper for children and are selected in the same way as for adults. The age and weight of the child, as well as the list of indications and contraindications for use, should always be taken into account. All antibacterial drugs in childhood are prescribed only by a pediatrician, because reactions to any medicinal substances in children are more violent than in adults and require careful monitoring.

Comparison of known antibacterial agents with flemoxin solutab

On Internet pages, patients share their experience of using antibiotics, give advice to each other, inclining them towards one or another remedy. Let's try to compare some analogs with flemoxin and highlight which one is better.

Instructions for use

Flemoxin Solutab is intended for oral use only. The tablets should be taken before, during or after meals. They can be swallowed whole, chewed with a glass of plain water, or divided into pieces. You can also dilute the tablet in water to form a suspension (100 ml) or syrup (20 ml), which has a pleasant fruity taste.

The dosage regimen of Flemoxin Solutaba is set individually for each patient. This takes into account the severity of the disease, the sensitivity of the pathogen to the drug, and the age of the patient.

For infectious-inflammatory pathologies of moderate and mild severity, it is advisable to use tablets according to the following scheme:

  • children aged 1 to 3 years: 250 mg of the drug 2 times a day or 125 mg 3 times a day;
  • children aged 3 to 10 years: 375 mg 2 times a day or 250 mg 3 times a day;
  • Children over 10 years of age and adult patients are prescribed 500-750 mg of the drug 2 times a day or 375-500 mg 3 times a day.

The total daily dose of the drug for children (including children under 1 year of age) should be 30-60 mg/kg body weight per day, divided into 2-3 doses.

Instructions for the treatment of diseases

  • When treating severe infectious diseases, as well as in hard-to-reach foci of infection (for example, acute otitis media), a three-time dose of the drug is necessary.
  • For acute uncomplicated gonorrhea, the patient is prescribed 3 g of Flemoxin Solutaba in 1 dose (simultaneously with 1 g of probenecid).
  • For patients with functional renal impairment with CC less than 10 ml/min, the dose of the drug is reduced by 15-50%.
  • For chronic diseases, severe infections and recurrent infections, adult patients are prescribed 0.75-1 g 3 times a day, and children - 60 mg/kg body weight per day (divided into 3 doses).
  • In case of infections of moderate and mild severity, Flemoxin Solutab is taken for 5-7 days. However, for infections caused by Streptococcus pyogenes, the duration of therapy should be at least 10 days.

Taking the pills must be continued for 48 hours after the signs of the disease disappear.

Comparison of drugs

Before choosing a drug, it is recommended to read the comparative characteristics and consult a doctor. The dosage should also be selected by the doctor, taking into account the age and other characteristics of the patient.

Similarities

The situations when medicine is prescribed are common: medicines are prescribed for infectious lesions of the digestive system (duodenitis, gastritis, peptic ulcer of the stomach or duodenum), skin, soft tissues, respiratory system (angina, laryngitis, pharyngitis, bronchitis), urinary and reproductive systems , ENT diseases (rhinitis, sinusitis).

There are other similarities: both antibiotics are synthetic, the drugs are not destroyed in the aggressive environment of the gastrointestinal tract. Absorption of the active substance occurs quickly: after 2 hours the maximum concentration is observed.

Both drugs are partially metabolized by the liver.

The drugs are well tolerated by adults and children, side effects are rare. In most cases, unwanted reactions go away on their own some time after the end of the course of therapy. Available only with a doctor's prescription.

Differences

Medicines have different effects on pathogenic bacteria: if Azithromycin does not destroy them completely, Flemoxin Solutab leads to the death of dangerous microorganisms. The first drug should not be taken more than once a day; the standard treatment regimen involves taking it for 3 days; in severe conditions, the course can be increased to 6 days. Flemoxin should be taken for 5 days; this drug is more easily tolerated by the body and is effective when an autoimmune disease joins an infectious one.


Azithromycin should not be taken more than once a day; the standard treatment regimen involves taking it for 3 days.

Flemoxin Solutab affects fewer types of bacteria, but its effectiveness is higher. Drugs are removed from the body in various ways: Flemoxin is removed through the intestines, Azithromycin - through the urinary system.

Which is cheaper?

Azithromycin is a cheaper medicine: you will have to pay from 120 to 215 rubles for a package. The cost of Flemoxin is 225-528 rubles.

Can I take it at the same time?

The simultaneous use of these aggressive medications is contraindicated.

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