Avamis or Nasonex – which is better? Advantages and disadvantages!

Compound similarities

What Nasonex and Avamys have in common are the following:

• classified as second generation synthetic glucocorticosteroid drugs;
• are produced in the form of a spray with a special dosing system;
• the main indication is allergic rhinitis, some doctors recommend using them for inflammation of the adenoids;
• allowed for children (from 2 years);
• have low concentrations of active substances, due to which they do not lead to addiction;
• the therapeutic effect is cumulative;
• When taken correctly, hormones are practically not observed in the blood.

One dose of spray contains 50 mcg of anhydrous mometasone furoate and auxiliary components: dispersed cellulose (sodium carboxymethylcellulose and MCC), glycerin, citric acid, polysorbate-80, sodium citrate dihydrate, benzalkonium chloride solution, purified water.

Treatment of adenoids

For the treatment of adenoid formations, the drug "Avamys" is often prescribed. This is due to the fact that the use of Nasonex spray and its combination with other hormonal agents can cause very negative consequences. In particular, it leads to metabolic disorders. Side effects such as severe dizziness and nosebleeds are sometimes observed. Using Avamis spray does not lead to such problems. Moreover, if you follow all the doctor’s recommendations, this method of treatment gives positive results in a short time. For the treatment of allergic rhinitis and adenoid formations, the drug "Avamys" is often used. An analogue of this product, Nasonex spray, is also highly effective and has a similar effect. However, the decision to use a particular medication should be made only by a doctor, taking into account the individual characteristics of your body.

Side effects of Nasonex and Avamis

Each dose contains 50 mcg of the hormonal substance mometasone furoate. The preparation also contains auxiliary elements. Thanks to its unique composition, the product has pronounced anti-inflammatory properties and has an antiallergic effect.

Indications for use of the substance include the following:

• allergic rhinitis of a seasonal or year-round nature;
• acute sinusitis;
• relapses of chronic sinusitis;
• prevention of allergic rhinitis;
• acute form of rhinosinusitis, which is accompanied by mild or moderate symptoms;
• nasal polyposis, which is accompanied by impaired breathing and sense of smell.

To cope with the problem, you need to strictly follow the instructions. For the allergic form of the disease, adults and children over 12 years of age are prescribed 2 injections once a day. In difficult situations, the dosage is increased to 4 injections. As the manifestations of the disease decrease, the volume of the drug can be reduced to 1 injection. Children 2-11 years old are usually prescribed 1 dose once a day. Improvement can be achieved during the first day of using the product.

For relapses of chronic sinusitis, Nasonex should be combined with antibacterial drugs. In this case, a single dose for adult patients is 2-4 administrations 2 times a day. The specific amount is selected by the doctor - it all depends on the characteristics of the disease. After reducing the manifestations of the pathology, the daily dosage of the medication can be reduced.

Before using the spray, the container with the drug should be shaken well. After which it is recommended to make 5-7 calibration clicks, which help to dose the product correctly. If the spray has not been used for more than 2 weeks, these manipulations are repeated.

Side effects of the 2 glucocorticosteroid drugs are similar and observed with the same frequency. These include:

• anaphylactic shock;
• Quincke's edema;
• the appearance of urticaria;
• formation of bronchospasm;
• hyperemia of the skin;
• itching, burning;
• irritation of mucous membranes;
• headache;
• nosebleeds;
• unpleasant taste in the mouth;
• feeling of dryness in the nose;
• increased intraocular pressure (rare).

If adverse reactions occur, you should quickly stop taking the medication and consult an allergist for advice.

Nasonex and Avamis - what's the difference?

There are contraindications, consult a specialist

Both drugs belong to the same pharmaceutical group, since Nasonex and Avamis contain second-generation synthetic corticosteroids. However, the active ingredients in them are different:

• mometasone in Nasonex,
• fluticasone in Avamis.

Since these medications are positioned as intranasal, they are produced in the form of a spray with a special dosing system. One injection is equivalent to 1 dose of Nasonex and is a 0.1 mg aqueous suspension containing 0.05 mg of finely divided mometasone. For the second drug, 1 injection is 0.05 mg of a suspension containing 27.5 μg of fluticasone.

Avamis is produced by the international company GlaxoSmithKline in the UK (instructions), and Nasonex is produced by the Belgian company Schering-Plough Labo (instructions).

Release form

• Dosed spray Nasonex Sinus. Polyethylene bottles 10 g, packaging No. 1. Each bottle is equipped with a protective cap and a spray nozzle. The contents of the bottle are designed for 60 doses, each of which contains 50 mcg of active substance.
• Nasonex metered spray. Polyethylene bottles 18 g, packaging No. 1. Each bottle is equipped with a protective cap and a spray nozzle. The contents of the bottle are designed for 140 doses, each of which contains 50 mcg of active substance.

The contents of the bottle are an opaque suspension of almost white or off-white color.

Review of effective and cheap analogues

The range of hormonal inhalers that have the same indications as the drug in question is quite wide. They may have different active substances, but have a similar (complex) effect: eliminate inflammation, relieve swelling, relieve suffocation and signs of allergies. The price of some of them is comparable to the cost of Nasonex, others are cheaper.

• Flixonase (England) or Nasonex – what to choose? The first one costs 760-815 rubles, so there will be no savings from the purchase. As a rule, they buy it if there is no second option and the price is not an issue. The main component in its composition is fluticasone propinate (120 doses). There are no significant differences between the medications in terms of prescriptions, contraindications and side effects. The advantage of Flixonase is that it copes not only with allergic rhinitis, but also eliminates the secondary manifestations of this pathology: redness, swelling, itching of the eyelids and lacrimation. But its use in pediatrics is allowed only from 4 years of age.
• Nasonex or Avamis (UK) - which is better for treating a runny nose of an allergic nature? The second drug is developed on the basis of fluticasone furoate; one can contains 120 doses. You can buy it for 650 rubles. The composition is no different, other parameters are also identical. It is shown from 2 years old. According to pediatric otolaryngologists, Avamis is more suitable for the treatment of adenoid growths. It restores nasal breathing well, removes swelling, and stops the growth of adenoids. At the same time, it is better tolerated and does not provoke dryness and nosebleeds. But Avamys is not used for prevention.
• What is better – Dezrinit (Israel) or Nasonex? The price of Israeli medicine is from 390 to 430 rubles. Its spectrum of action is somewhat wider: it eliminates not only allergic manifestations, but also the inflammatory process in the nasopharynx. It can also be used to treat asthma and COPD. Otherwise there is no difference.
• Fluticasone. How is it different from Nasonex? This is a spray that contains fluticasone propionate and non-alkonium chloride. The cost of the medicine is from 350 rubles. It does not give dangerous side effects, but it actively fights chronic and acute nasal congestion. For children it can be used from 4 years of age.
• Nasonex or Nazarel (Czech Republic) - which is better in terms of effectiveness, side effects and price? Nazarel contains fluticasone propinate in the amount of 120 doses. Sold for 320 rubles. The effect of these medications is completely identical: they very successfully treat acute and allergic rhinitis and quickly relieve congestion. Neither of them is inferior to the other in efficiency and speed. The disadvantage of Nazarel is that it is produced in only one dosage - 50 mcg per dose. And, unlike Nasonex, it is allowed to be used only from 4 years of age, while its “competitor” can be prescribed from 2 years of age. In addition, the list of its “side effects” includes growth retardation in children.
• Sinoflurin. Can this domestic product compete with Nasonex? If we talk about the price, then yes, because it is 320 rubles, that is, almost 3 times lower. The drug belongs to the same group of glucocorticosteroids, but has a different composition - it contains fluticasone propionate. Very effectively relieves inflammation. Allowed from 4 years.
• Nasobek. This is the most inexpensive “rival” of Nazonex: you can buy it for 170 rubles. Previously, it was produced by two enterprises - Teva (Israel) and Ivex Pharmaceuticals (Czech Republic). But in 2011, the Czech company’s registration permit expired, so Teva is the only supplier of this medicine to the Russian market. The drug contains beclamethasone in the amount of 200 doses. This spray not only fights rhinitis, but also produces an immunosuppressive effect (increases cellular immunity) and reduces the amount of mucus in the nose. It is also advisable to use it for vasomotor rhinitis. It rarely causes unwanted reactions, but its use is only permissible from 6 years of age, and it cannot be used for prophylactic purposes. The medicine is strictly prohibited in the 1st trimester of pregnancy.

Since the medicine is quite expensive, there is often a need to find analogs and replacements that are cheaper than Nasonex. In this case, the effect of the medicine should be the same as that of expensive hormonal drugs.

To choose an adequate replacement product, you need to know the cost of Nasonex. So, 60 doses of the medicine will cost about 500 rubles, 120 doses will cost about 850 rubles.

So, analogues of Nazonex spray include the following:

1. Rinoclenil - its active component is beclamethasone. 200 doses of the drug will cost approximately 350 rubles.
2. Flixonase – the active ingredient of this drug is fluticasone propionate. A bottle containing 120 doses of the substance costs about 750 rubles.
3. Nazarel - its active component is fluticasone propionate. At the same time, 120 doses of the medicine cost only 320 rubles.
4. Avamis - the active ingredient of the drug is fluticasone furoate. Moreover, 120 doses of the substance cost 650 rubles.
5. Nasobek – the active ingredient is beclamethasone. Moreover, 200 doses of the substance cost only 170 rubles.
6. Sinoflurin – the active ingredient of the drug is fluticasone propionate. 120 doses of the substance cost 430 rubles.

It is strictly forbidden to choose the cheapest product from the list of analogues. Before starting therapy, you should definitely consult your doctor. The specialist must select an effective medicine based on the history of the disease and its severity. Self-medication can cause dangerous side effects and seriously worsen a person’s condition.

Detailed review of the use of Nasonex

"Avamys" is prescribed for aggravated stages of adenoid pathogenesis

Yes it's true. The hormonal potent synthetic corticosteroid drug "Avamys", by prescription (and only!) is prescribed to children with the following symptoms of adenoid hyperplasia:

• Chronic nasal adenoiditis, which cannot be effectively treated with conservative medication, the adenoid epidermis continues to grow. The primary stages and mild degrees of the condition of the adenoids are not consolidated (after medicinal and physiotherapeutic effects), they pass to II and III operable formations.
• Clinical history, according to regular information from incoming laboratory tests, shows that the blood formula is changing for the worse, and the maximum percentage of leukocyte cells (leukocytes) is fixed. This is an alarming, threatening indicator. Since leukocytosis (bleeding), which occurs due to chronic, sluggish adenoid intoxication, is, unfortunately, not such a rare phenomenon.

• But, the conclusions of an ultrasound computer study indicate that the parenchyma of the nasal glands is not completely necrotic by pathogenic microflora. There is a chance and opportunity to preserve healthy adenoid layers (areas) in the nasal canals. Do not surgically excise, or freeze (liquid nitrogen) the nasal tonsils as an organ.

Related articles A super way to get rid of adenoids forever: expensive, but reliable - Nobel Prize to STIOTRON

In a word, in context - “Nasonex” or “Avamys: which is better in this particularly negative period for adenoids? " , undoubtedly - "Avamis". If there is at least 1% guaranteed, the slightest chance of preserving the natural barrier in a child’s small nose, curing it, bringing it to a safe state, of course – Avamis, and there is no need to doubt it.

Dear parents! Read the corresponding article on our website - “Avamys”: instructions for use for adenoids .” It contains information that will be useful for parents in terms of complete information about hormonal nasal medications.

As always, at the end of the text material there are short instructions, wishes, recommendations and useful tips on the topic. Both “Avamys” and, undoubtedly, “light” in comparison with it “Nasonex” have the right to timely save children from insidious adenoid vegetation. The only thing that parents should not forget is caution, and caution again, with the use of both one corticosteroid and the second. Caution and full coordination of actions with the treating pediatric otolaryngologist, consultation with an endocrinologist. And everything will be wonderful!

Side effects of Nasonex and Avamis

The drug has anti-inflammatory activity and has an antiallergic effect.

When treating allergic rhinitis in adults, the following are possible:

• pharyngitis;
• nosebleeds (bleeding may be obvious or blood may be present in the mucus released from the nose);
• irritation of the mucous membrane in the nasal cavity;
• burning sensation in the nose.

In children receiving Nasonex for the treatment of allergic rhinitis, the following was observed:

• nosebleeds;
• irritation of the nasal mucosa;
• headache;
• sneezing.

Nosebleeds usually stop on their own and are not severe. They occur with a frequency comparable to the frequency of their occurrence when using placebo (5%), but less or equal than when using other glucocorticosteroids for intranasal use.

Nasonex analogues were used for active control; with their use, the incidence of nosebleeds was up to 15%.

Other adverse reactions in the group of patients receiving mometasone developed with the same frequency as in patients who received placebo.

When prescribing the drug for sinusitis/sinusitis, when Nasonex is used as an adjuvant to relieve swelling of the drainage holes, reduce secretion production and facilitate the discharge of mucus from the paranasal sinuses, the following were recorded in adolescents and adults:

• pharyngitis;
• headache;
• irritation and/or burning of the nasal mucosa.

Bleeding was moderate, and the frequency of its occurrence when using the spray was only slightly higher than the frequency of its occurrence when using placebo (5% and 4%, respectively, for Nasonex and placebo).

Cases of development of ocular hypertension or perforation of the nasal septum have been reported extremely rarely when using endonasal corticosteroids.

Patients tolerate combination therapy with Loratadine well. Drug interactions with other drugs have not been studied.

Comparison of safety of Avamys and Nasonex

The safety of a drug includes many factors.

At the same time, in Avamis it is quite similar to Nasonex. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing metabolism in Avamis, as well as in Nasonex, we look at which organ is the metabolizing organ and how critical the effect on it is.

The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Avamis does not have any risks when used, just like Nasonex.

Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Avamis and Nasonex.

Nasonex or flixonase - which is better?

When choosing flixonase or nasonex, it is worth considering that the first remedy is not much cheaper. Therefore, it can hardly be called an inexpensive analogue. Flixonase is usually used if for some reason it is not possible to buy Nasonex. These sprays have similar active ingredients. They also have the same list of indications and contraindications. These medications also have the same side effects.

The only drawback is the age restrictions. Thus, Flixonase can only be used from 4 years of age, while Nasonex can be used from 2 years of age.

The advantage of this remedy is the ability to eliminate unpleasant eye manifestations that often accompany allergic reactions. These include lacrimation, swelling, redness, and itching of the eyelids. In general, these substances can be called interchangeable.

Nazarel has a lower cost compared to Nasonex. It is often used to treat children. Moreover, the principle of action of these drugs is the same. Many patients note that Nazarel is no less effective than Nasonex. Moreover, it allows you to get the same therapeutic effect.

The only drawback of Nazarel is the age limit. The product can only be used from 4 years of age, while Nasonex is also prescribed for 2-year-old children. In addition, Nazarel is produced in only one dosage, namely 50 mcg in each dose.

Sometimes patients are faced with the question of choosing – Polydex or Nasonex. It must be taken into account that these substances have different effects on the body. This is due to differences in the composition of the drugs.

Polydexa is a combination drug. It includes dexamethasone, which reduces allergy symptoms. It also contains phenylephrine, which has a vasoconstrictor effect, which makes breathing easier for the patient. In addition, the drug includes antibacterial components - polymyxan and neomycin. Due to this, the drug allows you to cope with bacterial microorganisms.

The instructions for nasonex analogues indicate that all of these drugs have an excellent effect and help cope with the symptoms of various pathologies. It is very important to use these substances under the supervision of a doctor. The specialist will be able to select the optimal remedy depending on the clinical picture and severity of the disease.

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Comparison of the effectiveness of Avamis and Nasonex

The effectiveness of Avamys is quite similar to Nasonex - this means that the ability of the drug substance to provide the maximum possible effect is similar.
For example, if the therapeutic effect of Avamis is more pronounced, then using Nasonex even in large doses will not achieve this effect.

Also, the speed of therapy - an indicator of the speed of therapeutic action - is approximately the same for Avamis and Nasonex. And bioavailability, that is, the amount of a drug reaching its site of action in the body, is similar. The higher the bioavailability, the less it will be lost during absorption and use by the body.

Pharmacodynamics and pharmacokinetics

The active substance of the spray is a synthetic corticosteroid for local (inhalation) use, therefore, the drug Nasonex is hormonal.

Pharmacodynamics

A feature of mometasone furoate is its ability to relieve inflammation and inhibit the development of an allergic reaction, even when used in doses at which systemic effects do not develop.

The substance inhibits the release of inflammatory mediators, stimulates the production of lipomodulin, which is an inhibitor of phospholipase A. Due to this, the release of arachidonic acid is reduced and, accordingly, the synthesis of its metabolic products (Pg and endoperoxides) is suppressed.

Reduces the formation of a chemotaxis substance, influencing “late” (delayed) allergic reactions, and also prevents the development of an immediate allergic reaction.

Studies with provocative tests with the application of antigens to the nasal mucosa have shown that Nasonex nasal spray exhibits high anti-inflammatory activity both at the early and late stages of the development of an allergic reaction.

This is confirmed (compared to placebo) by a decrease in eosinophil activity and histamine levels, as well as a decrease (compared to the baseline) in the number of neutrophils, eosinophils, and epithelial tissue cell adhesion proteins.

In approximately a third of patients (28%) with seasonal allergic rhinitis, a pronounced clinical effect was achieved within twelve hours after the first inhalation. In half of the patients, improvement occurred on average within 1.5 days (35.9 hours).

In addition, in patients suffering from seasonal rhinitis, the drug showed significant effectiveness in reducing the severity of eye symptoms (itching, lacrimation, redness).

Pharmacokinetics

The bioavailability of mometasone when applied topically is negligible (does not exceed 0.1%).

The substance is practically undetectable in blood plasma. The suspension is very poorly absorbed from the digestive canal, and the small amount that can be swallowed and has time to be absorbed undergoes active metabolism even before excretion.

Metabolites are excreted primarily in bile and, in small quantities, in urine.

Vasomotor rhinitis - symptoms

Both allergic and neurovegetative runny nose are accompanied by severe fatigue. Most patients complain of sleep disturbances and headaches. For some, appetite decreases. Problems with breathing through the nose lead to impaired ventilation of the lungs. Against this background, blood circulation in the cardiovascular system and brain worsens. Chronic runny nose also has symptoms such as:

• frequent bouts of sneezing;
• itching in the nasal cavity;
• copious nasal discharge;
• lacrimation;
• hyperemia of the skin of the eyelids and face;
• hearing impairment;
• tachycardia.

How to take Nasonex and Avamys?

The active ingredients in the medications are different: Nasonex has mometasone, Avamis has fluticasone.

They are produced by different companies: Avamis - GlaxoSmithKline (UK), Nasonex - Schering-Plough Labo (Belgium).

The British drug Avamis acts faster and more efficiently, because the concentration of the main substance in it is higher.

Despite similar pharmacodynamics, the British drug acts faster and more efficiently, since the concentration of the main substance in it is higher. In addition, unlike mometasone, the effect of fluticasone on tissue is stronger. Based on this, Nasonex is a more gentle drug that is prescribed more often for preventive purposes.

Doctors also recommend using the medicine in complex therapy for sinusitis, as it speeds up recovery.

The instructions indicate the same modes of use of the drugs:

• for acute rhinitis - 2 injections into each nostril once a day for adults and 1 injection for children;
• after achieving a therapeutic effect for adults, you can reduce the dosage - 1 injection once.

Avamis or Nazonex – which is better? This question is relevant for many people. Avamis has a similar composition and can be used from 2 years of age. When choosing Nasonex or Avamis, it is worth considering that all the indications, side effects and contraindications of these drugs are completely the same.

At the same time, Avamis is somewhat cheaper. Therefore, when prescribing Avamis or Nasonex for adenoids, pediatricians most often choose an inexpensive analogue. Clinical studies of adenoiditis confirm the correctness of this prescription.

Thanks to the use of Avamis, it is possible to stabilize breathing in children and cope with swelling. At the same time, the size of the adenoids does not increase. Many patients note a milder effect of the substance. At the same time, Nasonex can provoke increased dryness of the mucous membranes and even cause bleeding.

The difference between the sprays is also the packaging. Nasonex is placed in a plastic bottle, while Avamis is released in a special plastic glass. The only drawback of Avamis is that it cannot be used for prophylactic purposes, unlike Nasonex.

To choose an effective remedy, you need to evaluate the effect of these drugs on the body. Thus, derinat is an immunomodulator, which contains water. Thanks to this, the drug quickly penetrates the blood and spreads throughout the body. This medicine is used for inflammation that has been present for a long time. Its action begins after a few days.

There are practically no contraindications to the use of the product. The only limitation is considered intolerance to the ingredients of the substance.

Most often, Nasonex and Derinat are prescribed simultaneously. The first remedy begins to act on the first day of use. At the same time, derinat helps strengthen the body, increase its resistance to infections and stimulates the recovery process.

About the clinical and therapeutic essence of Nasonex as a pharmaceutical steroid

The dominant component in this nasal medication is a synthetic corticosteroid - Mometasone furoate. This is a substance created by synthetic analysis. The artificial genetic formula (hormone cells) is based on a natural analogue of human hormonal secretion.

Note! The factor of excess corticosteroids in the children's body becomes important. Clinicians note that when treating adenoid vegetation with pharmacological steroids in children, it is necessary to take into account an extraordinary aspect - the parallel content of physiological hormones and incoming synthetic steroids .

Pediatric endocrinologists, like no one else, know the importance of the hormonal endocrine system in a child’s body. A sharp imbalance (increase/decrease) in the well-functioning process of reduction and genesis of hormonal cells leads to severe diseases:

• “Graves syndrome” (acquired pathology of the thyroid gland);
• Improper metabolism, leading to “elephantiasis” of the lower and upper extremities, pasty looseness of the muscle epidermis (obesity);
• Pancreatitis is a disease-causing condition of the pancreas.

Related articles Salt cave for adenoids: halotherapy
The nasopharyngeal glands consist of a unique lymphoid tissue. The main source of vital activity of the tonsils lies in the normal, healthy homeostasis of the lymphatic structure. And, in turn, it is inextricably linked with the hormonal endocrine sphere.

That is why hormones, in themselves, are intense biological activators of ongoing reactions and processes in the body. Harmoniously and correctly selected in the dosage of drugs, artificially created steroid compounds are most effectively capable of changing the disease status in any organ of the body. They quickly and steadily influence, from a destructive perspective (gene-cellular level), the harmful etiopathology of micropathogenic flora.

"Nasonex" was invented by pharmacologists as a lightweight synthetic steroid. It is prescribed, in most cases, when children undergoing a course of conservative therapy in the initial stages of adenoid hyperplasia need to consolidate the positive changes achieved in treatment. At this period and phase of adenoids, the parents’ question to the ENT doctor is “Nasonex” or “Avamys: which is better now for adenoids? “, the answer will be unequivocal - “Of course, Nasonex!”

Aerosol irrigation of adenoid tumors in the nose with Nasonex (1 injection per 2 days is enough) will visually demonstrate improved dynamics in healing:

1. For allergic rhinitis and sinusitis, it significantly relieves severe nasal congestion. The voice will not sound “pronounced”, with a nasal tint;
2. In case of nasopharyngeal adenoiditis, characterized by night snoring, apnea (sudden stops of breathing during sleep), it will provide sick children with free nasal breathing. A restful sleep, without frightening snoring and interruptions in the breathing rhythm;
3. A few days of using Nasonex is enough for children to stop having headaches and dizziness.

Thanks to these encouraging manifestations in children and parents, the mood improves, optimism rises and strengthens - the adenoids recede!

Carefully! You should never force the use of Nasonex on your own! Only under the supervision of an otolaryngologist, upon agreement and permission in the mode of frequency of treatment of the child’s nasal cavities . Don't risk your children's overall health!

Nasonex spray: instructions for use

Nasonex is not recommended for use in the following cases:

• individual intolerance to the active substance;
• age up to 2 years;
• viral, bacterial or fungal infections;
• for tuberculosis;
• when the upper respiratory tract and organs of vision are affected by the herpes simplex virus;
• after recently undergoing surgery in the nasal cavity.

Nasonex is not recommended for viral, bacterial or fungal infections.

Avamis has fewer contraindications. These include:

• hypersensitivity to the main component of the drug;
• severe liver dysfunction;
• simultaneous use of the drug with Ritonavir.

During pregnancy and breastfeeding, taking medications is allowed only when the benefit to the mother outweighs the risk to the child.

Indications for use of Nasonex are:

• allergic rhinitis (seasonal or year-round) in children, adolescents and adults;
• exacerbation of chronic sinusitis (the drug is prescribed as an adjunct to antibiotic therapy) in adolescents and adults;
• prevention of moderate/severe seasonal allergic rhinitis (it is considered optimal to start using the spray no later than 2 weeks before the expected start of the dusting period).

Children are prescribed Nasonex allergy spray from the age of two. For the treatment of sinusitis in pediatrics, it is used in children over twelve years of age.

Contraindications to the use of Nasonex are:

• intolerance to any of its constituent components;
• the presence of an untreated/undertreated local infection, provided that the nasal mucosa is involved in the process;
• active or latent tuberculosis infection of the respiratory tract;
• untreated bacterial, systemic viral or mycotic infection, as well as an infection caused by the herpes simplex virus with eye damage (in some cases, the drug can be prescribed as an exception as directed by the attending physician).

If the patient has recently suffered a nasal injury or nasal surgery, the use of the spray is contraindicated until the wound has healed.

General recommendations

The drug is intended for intranasal administration (used in the form of inhalations) of the suspension contained in the bottle. The procedure is carried out using a dosing nozzle, which is supplied with each bottle of Nasonex.

Before using the spray for the first time, it is “calibrated” by pressing the dosing device 6-7 times. “Calibration” allows you to establish a stereotypical supply of medicine. In this case, each press of the dosing device ensures the release of 100 mg of suspension into the nasal cavity, which contains 50 mcg of a chemically pure active substance.

Before use, the bottle must be shaken vigorously each time.

The standard prophylactic/therapeutic dose for adolescents over the age of twelve and adult patients (including the elderly) is two inhalations into each nasal passage as a single dose (200 mcg of mometasone per day).

After achieving the desired therapeutic effect, the dose is reduced to 100 mcg/day. (one inhalation in each nasal passage once).

If it was not possible to achieve the desired effect when using a therapeutic dose, the dose can be increased to 400 mcg/day. That is, the patient should take up to four inhalations once in each nasal passage. Reducing the severity of symptoms of allergic rhinitis is an indication for dose reduction.

Clinical improvement after the first use of mometasone is usually noticeable within 12 hours after the first inhalation.

For children under 11 years of age, it is recommended to take one inhalation into each nasal passage once for allergies. The total dose is 100 mcg/day.

Since Nasonex is not a nasal drop, but a spray, when inhaling, you should keep your head straight, without throwing it back.

For patients over twelve years of age, including the elderly, the recommended therapeutic dose is two inhalations into each nostril, 2 times a day. The total dose is 400 mcg/day.

The drug is used as an adjuvant, complementing the main treatment.

If clinical improvement cannot be achieved using the drug at a standard dosage, the dose may be increased to 800 mcg/day. (four inhalations into each nasal passage, 2 times a day). After the severity of symptoms decreases, the dose should be reduced.

After 12 months of use of Nasonex, there were no signs of atrophy of the nasal mucosa; in addition, mometasone tended to improve the histological picture when examining a tissue sample of the nasal mucosa.

Enlarged adenoids are a fairly common complication of allergic rhinitis in young children. Prescribing Nasonex to children with adenoids can relieve swelling and often prevent the need for surgical intervention.

Reviews of Nasonex for adenoids indicate that the effect is achieved by suppressing lymphoid tissue, but it takes quite a long time to achieve it. In addition, in cases of severe inflammation, the drug is not very effective.

As a hormonal agent, the spray also additionally suppresses local immunity, and therefore, after its discontinuation, inflammation in the adenoids may resume. External manifestations of inflammation are the appearance of mucus flowing down the back wall of the throat.

To relieve this condition, doctors recommend taking a course of anti-inflammatory treatment for adenoid vegetations. In this case, inhalations through a nebulizer with Cycloferon, supplemented by rinsing the nasopharynx using the nasopharyngeal shower method, which are carried out in an ENT office, may be effective.

Dr. Komarovsky recommends, as an addition to the treatment of adenoids, to reconsider the organization of the child’s lifestyle. Since one of the reasons for the growth of adenoids is a decrease in immunity, it is very important that the immune system functions as best as possible.

To minimize the risk of an increase in the size of the pharyngeal tonsils, the child should eat properly, walk in the fresh air, temper himself, play sports and have as little contact as possible with household chemicals and dust.

After the inflammation disappears, it is usually not necessary to repeat the course of intranasal GCS.

Nasonex intranasal spray is a well-known and sought-after Belgian product that firmly took its place on the shelves of our pharmacies 9 years ago. Available in several dosages from 30 to 120 doses. It belongs to the group of glucocorticoids, the active substance is mometasone furoate. It has a pronounced anti-allergic and anti-inflammatory effect. Used for symptomatic therapy for all types of allergic rhinitis, for the treatment of polyposis, sinusitis, adenoids.

It is prohibited to prescribe such a drug for up to 2 years, in case of a hyperreaction to its components, after surgical manipulations and injuries to the nose. It is not suitable for patients suffering from liver failure or frequent nosebleeds. Relative contraindications are pregnancy, lactation and taking other hormones.

When using the spray, adverse reactions may develop: skin rash, burning, irritation, pain, dryness and sores in the nose, headache. Very rarely, perforation of the nasal septum, dysfunction of the adrenal glands, increased intraocular pressure, impaired vision, and taste are recorded. It can also lead to more serious consequences - angioedema, anaphylaxis.

To summarize, Nasonex has a number of important advantages: low incidence of serious side effects, high concentration after irrigation of the nasal passages, speed of action and proven effectiveness, absence of ethanol. But there is also a minus - the high price. The cost of the drug depends on the number of doses. If there are 60 of them - from 460 rubles, if 120 - from 805 rubles. up to 1000 rub. And this factor cannot be discounted, especially if treatment will take a long time.

Reviews about the drug "Avamys"

For many who are prescribed Avamys spray, the instructions, price and reviews of the drug are studied first. This is right. Everyone should know how quickly the drug works and what side effects it has. In most cases, the medication is reviewed well. Already within the first day after the start of treatment, you can notice positive dynamics.

Negative reviews are most often associated with incorrect dosage or individual intolerance. Patients with impaired liver function may find the drug ineffective.

Nasonex or Nasobek

When choosing Nasonex or Nasobek, it is worth analyzing the composition of these medications. Nasobek has another active component - beclomethasone. In addition, this drug also has an immunosuppressive effect, which ensures the restoration of local immunity. This substance also helps reduce mucus production in the nasal passages.

The undoubted advantage of the drug nasobek is its low cost. It is excellently tolerated by patients even with long-term therapy. It can be used to treat vasomotor rhinitis.

At the same time, the spray also has certain disadvantages, one of which is the age limit. This substance can only be used from 6 years of age. It is also prohibited to use nasobek to prevent any form of allergic rhinitis.

Similarities between Avamys and Nasonex

Many people are interested in the question: “Is Avamys spray an analogue of Nasonex?” To answer this question unambiguously, you should study the main characteristics of these drugs. The drug "Avamys" is a nasal spray containing hormonal components. This medicine is produced in the UK. The drug "Nasonex" is also produced in the form of a spray, but the manufacturing country is Belgium. The drugs "Avamys" and "Nasonex" are hormonal drugs, so you should definitely get medical advice before using them. According to their indications, these drugs are quite similar. They are used for:

1. Treatment of seasonal and year-round rhinitis of an allergic nature.

2. Destruction of adenoid transformations.

3. Treatment of sinusitis, sinusitis, elimination of the consequences of the underlying disease.

At the same time, Nasonex spray has one significant feature: it can be used as a means of prevention. The similarity between the drugs "Avamys" and "Nasonex" also lies in the fact that the choice of the desired dosage is carried out depending on the age of the patient and the diagnosis.

Nasonex or desrinitis

Desrinit or Nasonex – which is better? These substances have certain differences. Thus, the Israeli medicine desrinit is a spray that is intended for intranasal and inhalation use. This remedy is used for symptoms of allergic rhinitis. It also successfully copes with inflammatory lesions of the nasopharynx.

When choosing Nasonex or Desrinit, it is worth considering that they have similar indications. In addition, desrinit can be used for inhalation, which is used to treat bronchial asthma and chronic pulmonary obstruction. The cost of this product is generally comparable to the price of Nasonex.

Nasonex or Avamis, which is better for adenoids?

Effective drugs Nasonex or Avamis help children recover and get better faster, since they contain effective components. As a rule, doctors prescribe these drugs for allergic rhinitis, adenoids and sinusitis. Despite the fact that medications have a positive effect on the healing process, they still have differences in composition.

The main substance in Nasonex is mometasone furoate, and in Avamys it is fluticasone furoate. All two components give a powerful effect. However, fluticasone furoate is still stronger, so treatment is faster with Avamys. However , both drugs quickly disperse throughout the body and enter the blood. This process is completely harmless for children. Studies and tests have shown that they are very difficult to detect in the blood. It is also worth highlighting that the products have minimal toxicity and side effects on the body.

Avamis or Nasonex, which is better for a child with adenoids? This question interests parents whose children have adenoids. After all, you want to buy not just an expensive drug, but also an effective one. However, you can choose one of the two options only after studying the features of the drug, as well as the composition.

It is worth noting that medicines are produced abroad - Great Britain and Belgium. The cost of drugs varies, Avamis wins in terms of price. Also, the concentration of the active substance in Nasonex is lower, so the medicine is used even during preventive measures. But Avamis is perfect for therapy, as it has a stronger concentration of the substance. Yet Nosonex is more often used in the treatment of adenoids in children.

As for contraindications, Avamis seems more preferable. The fact is that the list of contraindications is very small. It is not recommended to take the drug only for pregnant women and patients with kidney problems.

If a child has adenoids, but without rhinitis, then doctors advise taking Nasonex, because it quickly localizes swelling of the mucous membrane, restores the functioning of the eardrums and copes with inflammatory processes. During therapy, the mucous membrane does not dry out, which is an additional advantage. Avamis is prescribed more often for allergies and sinusitis.

In pharmacies you can find both drugs in spray form. This form of release is considered the most convenient and comfortable for the treatment of adenoids in children. Like all medicines, Avamis and Nasonex are sold with detailed instructions for use. This instruction describes the basic things: rules of use, composition, dosages by age category, treatment of rhinitis, adenoids and sinusitis.

Experts recommend shaking the can well before treatment and then treating the nasopharynx. It is important to remember that at high temperatures, drugs lose their effectiveness, so it is worth observing the timing and place of storage.

• Drug Nasonex

The drug Nasonex has a mild effect, so doctors often prescribe the drug as a preventative measure. The following advantages of Nasonex can be noted:

1. Convenient packaging, dispenser and size of the drug.
2. Economical use of funds.
3. Relieves swelling of the mucous membrane and nasal congestion.
4. Does not cause irritation or allergic reaction. While taking the medicine, the mucous membrane does not dry out.

International doctors believe that cheap drugs are addictive in children. However, Nasonex is able to cope with this problem. Moreover, medical practice has shown that the product effectively combats runny nose and other nasopharyngeal problems. Although the drug costs much more than Avamis.

• Avamys drug

To help with rhinitis: hormonal nasal spray No. 1

When choosing tafen or nasonex, it is worth considering that both drugs belong to the category of glucocorticosteroid hormones. Tafen contains another active component - budesonide. With its help, it is possible to cope with inflammatory processes, eliminate allergies, cleanse the body of harmful elements and prevent the production of histamine.

Tafen begins to act literally within 2-3 days of use. It can be used for prophylactic purposes for a long time. The only downside is the age limit. This medicine can only be used from 6 years of age.

Avamis or Nasonex: which is better?

Avamis and Nasonex are hormonal drugs

Searching for an analogue is a reasonable desire of the consumer to save money. Usually, domestically produced drugs are analogues. The absence of additional costs associated with the purchase of imported products makes them more affordable in the price range.

If we talk about Avamys and Nasonex, both sprays are produced by foreign companies: Great Britain and Belgium, respectively. Based on the cost criterion, Avamis is superior to Nasonex, since the price of the first drug is half as much.

Avamis and Nasonex are hormonal drugs. They should be prescribed by the attending physician based on test results. The dosage depends on the patient's age and diagnosis.

They have general indications for use:

• allergic rhinitis
• adenoids
• sinusitis
• sinusitis

Nasonex is approved for use for preventive purposes, but children under two years of age and patients who have undergone surgery in the nose and sinuses are prohibited from using it.

In terms of contraindications, Avamis spray is considered more loyal: it is recommended even during pregnancy, it is not contraindicated for people with impaired kidney function. Avamis will have to be abandoned if the patient is ill with ARVI. This is a significant disadvantage.

For adenoids, it is recommended to use Nasonex. If the disease is not accompanied by allergic rhinitis, Nasonex helps relieve swelling of the adenoids, which interferes with the normal functioning of the eardrums. If you have adenoids, you need to take oral allergy medications.

You can learn how to properly treat allergic rhinitis from the following video:

The choice between Avamys and Nasonex depends on the individual characteristics of the patient.