Instructions for use of the drug Amoxiclav

Sore throat is a serious disease that affects both children and adults. It is dangerous both in itself and the complications it causes. The ability of the disease to develop into a long-term chronic form also poses a threat to health.

To treat different forms of sore throat, various means are used, but for purulent diseases of a bacterial nature, only antibiotics are most effective. One of the most popular and high-quality remedies for the treatment of sore throat is Amoxiclav.

Composition, properties and release form of Amoxiclav

Amoxiclav tablets

The drug is available as tablets in dosages of 250, 500 or 875 mg, as well as suspension, syrup or drops, prescribed to children under 12 years of age.

The drug contains two main active substances: amoxicillin trihydrate and the potassium salt of clavulanic acid. The product also contains additional substances: colloidal silicon dioxide, talc, magnesium stearate, microcrystalline cellulose and other auxiliary components.

Amoxicillin is a semisynthetic antibiotic from the penicillin group with a wide spectrum of activity and has pronounced antibacterial activity.

Clavulanic acid prevents the rapid destruction of amoxicillin under the influence of beta-lactamases, and also has its own antibacterial activity, enhancing the medicinal properties of the drug. Additional substances serve to bind and stabilize the drug in tablet form. The drug has bactericidal activity, inhibiting the synthesis of the bacterial wall.

Treatment of purulent sore throat

A purulent sore throat is quite difficult, especially when it comes to children.
In this case, the patient’s temperature rises to forty degrees, a strong pain occurs in the throat and a purulent plaque forms on the tonsils. In such a situation, you definitely cannot do without the use of antibacterial agents. Amoxiclav for purulent sore throat is prescribed in the following cases.

1. Adults and children over twelve years of age, one tablet up to three times a day. The dosage of the drug is five hundred milligrams. If a serious condition is observed, the dose is increased to eight hundred milligrams twice a day. The medication should be taken before eating and washed down with plenty of liquid.
2. For children under twelve years of age, take one tablet up to two to three times a day at a dosage of two hundred and fifty milligrams. The duration of the treatment process is from five to seven days.

Children under three years of age are prescribed medication in the form of a suspension. Before use, the powder must be diluted with water. Store only in the refrigerator. The bottle of suspension must be shaken before use. Basically, the dosage is from three to five milliliters of the product up to two to three times a day.

Use for sore throat

Amoxiclav is prescribed for sore throat of bacterial origin, purulent, lacunar. Like any other antibiotic, this remedy is powerless against a disease caused by viruses or fungi, and can even cause harm, so before using the product you need to make sure that bacteria are the cause of the disease. Only after this can Amoxiclav and any other antibiotics be prescribed.

In addition to tonsillitis, Amoxiclav is used against a huge number of bacterial infections of various organs - from the respiratory to the reproductive system, lesions of the skin, bones and soft tissues.

Amoxiclav for sore throat in children

Amoxiclav powder for suspension preparation

Under the age of 12 years, the drug is given to children mainly in the form of a suspension, in the following single dosage:

• Up to 3 months – 30 mg/kg per day, 2 times.
• Over 3 months - for mild infections - 25 mg/kg per day in 2 divided doses or 20 mg/kg per day in 3 divided doses. In severe conditions, 45 mg/kg per day in 2 doses or 40 mg/kg per day in 3 doses is prescribed.
• Children weighing more than 40 kg are prescribed 500 mg of the drug 2 times a day or 250 mg three times every 24 hours. For severe tonsillitis, the doctor may prescribe 875 mg twice a day or 500 mg three times a day.

It is best to take the drug with meals to reduce the risk of digestive upset. If the product is used in the form of a syrup or suspension, the dry powder must be diluted with clean boiled water.

Amoxiclav for sore throat in adults

For adult patients, Amoxiclav is prescribed for angina in the following dosage:

• For mild to moderate infections, take 500 mg twice within 24 hours or 250 mg three times.
• In severe forms of the disease or respiratory tract infections, including tonsillitis, the dose of the drug is increased to 500 mg three times a day or up to 575 mg twice a day.

The duration of treatment ranges from 5 to 14 days and is selected by the attending physician. You cannot shorten or extend the treatment period on your own without the decision of doctors. In the first case, there is a threat of insufficient impact on the infection and the transformation of sore throat into a chronic form. She is difficult to treat.

More information about the drug Amoxiclav can be found in the video:

What antibiotic tablets are best to take for sore throat?

Taking an antibiotic for too long threatens to destroy the beneficial microflora of the digestive system, damage the kidneys, develop antibiotic-associated colitis and other dangerous diseases with a chronic course.

Amoxiclav during pregnancy and breastfeeding

The drug is prescribed to a pregnant or nursing mother only if the expected effect outweighs the possible risks. When conducting experiments on animals, there was no teratogenic effect of the drug, but it is recommended to avoid it in the first trimester of pregnancy, since Amoxiclav can provoke necrotizing enterocolitis in the newborn.

Both amoxicillin and clavulanic acid can pass into breast milk. They cause diarrhea and thrush in infants.

Amoxiclav for sore throat in children

The drug Amoxiclav for sore throat is prescribed even in pediatrics. For children under 12 years of age, a powder form of the antibiotic is recommended for preparing a suspension. The powder is pre-dissolved with water (according to the instructions), shake the bottle until the particles are completely dissolved. The shelf life of the prepared suspension is 7 days; the medicine must be stored in the refrigerator.

Among the medical indications of the suspension are bacterial, follicular, catarrhal, purulent tonsillitis. The course of treatment is 5–7 days. According to the instructions for use, 1 measuring spoon corresponds to a medicine volume of 5 ml. Daily doses of Amoxiclav suspension depend on the age of the child, the stage of the pathological process, and are adjusted individually:

• up to 12 months: 2.5 ml twice a day;
• children from 1 to 7 years: 5 ml three times a day;
• from 7 to 14 years: 1 tbsp. l. for 1 daily dose.

An antibiotic is not prescribed for viral sore throat. Other medical contraindications include:

• individual intolerance by the body to active substances;
• complicated liver and kidney diseases;
• cholestatic jaundice;
• the body's predisposition to an allergic reaction;
• lymphocytic leukemia;
• Infectious mononucleosis.

Contraindications to the use of antibiotics

If kidney function is impaired, high doses of the drug may cause seizures

The following conditions and diseases are contraindications to the use of the drug:

• Hypersensitivity to the main and minor components of the product.
• Allergic reaction to penicillin antibiotics, cephalosporins or beta-lactams.
• Cholestatic (congestive) jaundice.
• Liver problems caused by taking antibiotics.
• Liver failure.
• Severe renal pathologies.
• Serious diseases of the digestive tract.
• Infectious mononucleosis.
• Lymphocytic leukemia.
• Pseudomembranous colitis.
• Simultaneous use of anticoagulants.

Using the drug without a doctor's prescription can be hazardous to health.

Possible side effects

Amoxiclav for angina can provoke the following negative manifestations:

• Diarrhea.
• Nausea.
• Gastritis.
• Colitis caused by antibiotics.
• Stomatitis.
• Black tongue.
• "Hairy" tongue.
• Hepatitis.
• Congestive jaundice.
• Changes in liver enzymes.
• Anaphylactic manifestations.
• Allergic vasculitis.
• Angioedema.
• Neutropenia.
• Thrombocytopenia or thrombocytosis.
• Agranulocytosis.
• Prolongation of prothrombin time.
• Increased bleeding time.
• Eosinophilia.
• Hemolytic anemia.
• Dizziness.
• Headache.
• Insomnia.
• Cramps.
• Increased excitability.
• Anxiety.
• Itching.
• Hives.
• Erythema.
• Dermatitis.
• Nephritis.
• Hematuria.
• Candidiasis.

Most side effects occur rarely, mainly when the frequency and dosage of taking the drug is violated.

Useful video about antibacterial drugs:

Signs and dangers of overdose

Mostly, a minor overdose results in severe stomach upset. The patient suffers from diarrhea, he may be tormented by nausea, in severe cases gastritis develops or worsens, and various forms of colitis may appear.

Most often, an overdose is expressed in an imbalance of electrolytes, which is especially dangerous for people with kidney failure or other problems with these organs.

Convulsions and crystalluria may develop, that is, increased loss of salts in the urine, which aggravates the course of kidney disease.

If an overdose is detected early (within 4 hours after taking an excessive dose of Amoxiclav), then gastric lavage is necessary to remove excess drug. After this, the patient is given a sorbent to eliminate the harmful effects of residues remaining in the digestive system. In particularly severe cases, hemodialysis may be used.

Interaction with other drugs

Amoxiclav for angina can interact with other drugs when taken simultaneously.

The use of the drug enhances the effect of indirect anticoagulants, reduces the effectiveness of oral contraceptives, increases the risk of breakthrough bleeding, Allopurinol, Phenylbutazol and diuretics increase the concentration of Amoxiclav.

Taking bacteriostatics causes the opposite effect.

Antibiotics for tonsillitis

The most significant causative agent of bacterial tonsillitis is group A beta-hemolytic streptococcus. Less common are tonsillitis caused by C and G streptococcus, pneumococcus, anaerobes, chlamydia and mycoplasmas.

Antibiotics for the treatment of bacterial tonsillitis are selected taking into account the spectrum of the main pathogens. Typically, beta-lactam antibiotics (penicillins and cephalosporins) are used. If there are contraindications to the use of beta-lactams, macrolides are prescribed.

What antibiotics can be used for tonsillitis?

For tonsillitis of a bacterial nature, the drugs of choice will be:

• Amoxicillin+clavulanic acid®;
• Amoxicillin®;
• Cefazolin®;
• Cefepime®;
• Cefotaxime®;
• Ceftazidime®;
• Ceftriaxone®;
• Cefuroxime®.

What antibiotics can be used to treat tonsillitis if you are allergic to beta-lactams?

Patients with contraindications to the prescription of penicillins and cephalosporins are prescribed macrolides:

• Azithromycin®;
• Josamycin®;
• Clarithromycin®;
• Midecamycin®;
• Spiramycin®.

Analogues of Amoxiclav for the treatment of sore throat

There are numerous drugs that are analogues of Amoxiclav:

How many days does the temperature last for sore throat and the method of treating the disease?

The listed drugs are only a small part of the drugs that either have a composition similar to Amoxiclav, or have a similar effect and are used in similar situations.

Use of the drug in children

Amoxiclav for angina in children under 6 years of age is used in the form of suspensions. The powder has a sweet taste, is easily taken orally, and does not cause discomfort. The suspension is supplied with a measuring spoon and a measuring cup. The duration of antibiotic use in children depends on the type of disease, but the treatment period should be at least 5 days. Sometimes it is increased to 2 weeks. If at the end of 14 days there is no therapeutic effect, you should consult a doctor. The doctor will select a similar drug. A child usually does not have an allergy to penicillin drugs. To establish the dosage, the doctor takes into account age and weight. The minimum amount of medication is 125 milligrams for preschool children and 250 mg for patients over 8 years of age. The amount of antibiotic taken depends on the severity of the disease. For purulent tonsillitis, the medicine is taken 2-3 times a day every 6-8 hours.

After making the suspension, it can be stored in the refrigerator for no longer than 7 days. After this time, the solution becomes unusable. It is better to give the medicine to children immediately after meals or while eating food to avoid the negative effects of the drug on the stomach. They sometimes react poorly to antibiotics if they are not used correctly. Vomiting may occur and the effectiveness of therapy will decrease.

Comments (9)

• Ira

  09/16/2018 at 23:18 |
  It is a very strong antibiotic that I have taken for tonsillitis. I would like to immediately warn those who have not taken it that this medicine should under no circumstances be taken on an empty stomach. If you experience stomach pain, you need to drink amoxiclav along with lactrofiltrum.

  Answer

  Expert Marina Rusetskaya

  08/18/2019 at 15:47 |

  Irina, amoxiclav, like other drugs, has its side effects.

  Of course, there are patients who cannot tolerate this medication: some experience abdominal pain, others have diarrhea.

  Almost all medications need to be taken either after or during meals; the doctor usually warns about this when prescribing the medication.

  If you experience abdominal pain, it is better to stop taking the drug and consult a doctor. The specialist will change the main antibiotic and prescribe additional therapy to relieve abdominal pain.

  The cause of abdominal pain is not any specific drug, but the ability of medications to irritate the gastric mucosa and cause gastritis.

  In addition, the doctor prescribes medications that restore normal intestinal flora, because The antibiotic “kills” absolutely all microorganisms in the intestines.

  During treatment, it is possible and necessary to take medications that normalize the intestinal microflora to eliminate the phenomena of dysbacteriosis.

  Patients are also recommended to drink natural kefirs, yoghurts and starter cultures. These fermented milk products contain bifidobacteria, which are necessary for proper intestinal function.

  The composition of the product must indicate CFU/l of at least 107/l.

  Answer

Side effects

Treatment of tonsillitis with Amoxiclav can lead to side effects. Often it is the presence of clavulanic acid in the composition of the drug that leads to their appearance. The main ones:

• disruption of the digestive system - cramps, pain, nausea, vomiting, diarrhea, bloating;
• allergies – swelling, rash, dermatitis;
• lack of sleep, headache, weakness, anxiety;
• anemia, decreased platelet levels in the blood;
• disruption of the liver and urinary system;
• candidiasis.

It is forbidden to take Amoxiclav on your own, since the cause of the disease can be fungal and viral pathogens that cannot be cured with antibacterial drugs. The use of antibiotics in such cases leads to a deterioration in the patient’s condition and damage to health.

Article verified by Anna Moschovis - family doctor.

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