Hexoral or tantum verde for cough

Compound

The composition of the medicine in the form of a solution includes the active component hexetidine (100 mg), it also contains auxiliary ingredients: polysorbate 60, ethanol 96%, anise oil, peppermint oil, eucalyptus and clove oils, citric acid monohydrate, levomenthol , sodium saccharin , methyl salicylate , azorubine, 85% water.
The composition of the medicine in the form of an aerosol includes the active component hexetidine (200 mg), as well as additional components: polysorbate 80, citric acid monohydrate, levomenthol, sodium saccharinate, sodium calcium edetate, eucalyptus leaf oil, sodium hydroxide, water.

pharmachologic effect

The abstract contains information that Hexoral is an antiseptic medicine .

The antimicrobial effect of this drug is due to the fact that it suppresses the oxidative reactions of the metabolic (the active substance is a thiamine ). Hexoral has a wide range of antifungal and antibacterial effects. It is active against Candida fungi and gram-positive bacteria. It can also be effective in treating infections caused by Pseudomonas aeruginosa, Proteus. Most bacterial strains are inhibited by the drug at a concentration of 100 mg/ml. However, there was no development of resistance to the drug.

There is also a weak anesthetic effect on the mucous membrane.

Effect of the drug

The medical effect of using Lugol is achieved by molecular iodine, which is its basis. Iodine has a local irritant and antiseptic effect, but Lugol cannot be considered a local spectrum antibiotic (like, for example, the same Hexoral). The action of "Lugol" is based on the ability to bind and neutralize proteins, which are pathogenic bacteria that cause damage to the oral cavity or larynx.

Lugol became a drug for the treatment of sore throats quite by accident, because it was invented to treat tuberculosis, but the effect turned out to be somewhat different from what was expected.

The solution also destroys staphylococcal infections, which are known for their persistence; the course of treatment can last up to one month without interruption. In Soviet times, dispenser sprays were not produced, and therefore the solution was produced in glass bottles of 25 and 50 milliliters. It was catastrophically inconvenient to use, because the liquid is not viscous and stains very strongly, leaving stains that are resistant to removal.

“Lugol” in glass can still be found today; such solutions are used for external treatment of mucous membranes (dip cotton swabs into the solution and moisten the affected area) or for preparing a solution for oral administration. It is believed that 2 drops of Lugol dissolved in a glass of water help cleanse the body. The drug is prescribed in this form to pregnant women in the third trimester.

Indications for use

Hexoral spray and solution are used in the following cases:

• for infectious inflammatory diseases of the pharynx and oral cavity;
• in the complex treatment of severe febrile or purulent diseases of the pharynx and oral cavity and pharynx, for which antibiotics and sulfonamides are prescribed;
• for tonsillitis ;
• for sore throat ;
• with pharyngitis
  ;
• for periodontopathies ;
• for gingivitis and bleeding gums;
• for aphthous ulcers, glossitis, stomatitis , as well as for the prevention of superinfections ;
• for candidal stomatitis , as well as a number of other fungal infections of the pharynx and oral cavity;
• in case of infection of the alveoli after the tooth has been removed;
• in the period before and after operations of the pharynx and oral cavity;
• to ensure additional oral hygiene for common diseases;
• to eliminate bad breath, in particular in people with disintegrating tumors of the pharynx and oral cavity;
• as an auxiliary drug in the treatment of colds.

Fight against viruses and bacteria: how they work

Hexoral and Tantum verde are deservedly popular among medical practitioners. But the scope of application of these funds differs slightly. To understand when aerosols and sprays are prescribed, you need to know the principles of their operation. Next we looked at how the drugs work.

Hexoral

Hexethidine is an antiseptic for topical use. It has a moderate antimicrobial effect - it destroys pathogenic microorganisms and prevents their reproduction. Once on the mucous membranes, Hexoral penetrates the cell wall of bacteria and suppresses some oxidative reactions. Hexethidine acts as a thiamine antagonist and affects key components of microbial metabolism.

How does he work:

1. Antibacterial action. Hexoral is a broad-spectrum antiseptic. It destroys many gram-negative and gram-positive bacteria and has a detrimental effect against the most common pathogens of throat and nose diseases.
2. Antifungal action. Fungi of the genus Candida are sensitive to the action of hexethidine. They often act as a secondary infection - as a complication after infection with viruses and bacteria.
3. Antiviral effect. Hexoral is effective against influenza virus type A, RS virus, and herpes simplex virus type 1. These viruses are more often detected when the respiratory tract is affected.
4. Anesthetic effect. The aerosol relieves sore throat and alleviates the patient's condition.
5. Drug resistance to Hexoral has not yet been identified. All declared viruses, fungi and bacteria are sensitive to the effects of the drug.

Hexethidine is practically not absorbed, does not penetrate deep into tissues and does not enter the systemic circulation. It acts only locally – where help is needed. After a single application, traces of the substance are detectable on the gum mucosa for 65 hours (but only 14 hours in the presence of plaque).

Tantum verde

The mechanism of action of benzydamine is not fully understood. It belongs to the NSAIDs, but does not act in the same way as the usual Paracetamol or Nurofen. Typically, drugs in this group suppress the activity of the COX enzyme, inhibit the production of prostaglandins and eliminate the inflammatory process. Benzidamine works differently. It does not affect cycloxygenases, and therefore does not have the usual side effects of NSAIDs.

Mechanism of action of Tantum verde:

1. Anti-inflammatory effect. It is assumed that benzydamine inhibits the activity of prostaglandin synthetase, an enzyme that is involved in the synthesis of prostaglandins and the initiation of the inflammatory response.
2. Antibacterial action. Benzidamine quickly penetrates the cell wall of bacteria, disrupts metabolic processes and leads to the death of microorganisms.
3. Antifungal action. The drug is effective against Candida albicans. It leads to structural changes in the cell wall of fungi and prevents their reproduction.
4. Local anesthetic effect. Benzydamine relieves sore throat and relieves the condition.

Instructions for use of Hexoral (Method and dosage)

Hexoral solution, instructions for use

The solution is indicated for rinsing the throat and mouth.

Adults and children over 3 years of age should use 15 ml of undiluted solution for rinsing; rinse the mouth and throat for at least 30 seconds. You need to do this twice – in the morning and in the evening. If it is necessary to treat diseases of the oral cavity, you can apply the solution using a tampon.

Since the active component adheres to the mucous membrane, providing an effect, it should be used after meals.

You can use the drug more often, as it is a safe remedy. This solution should not be swallowed. The duration of treatment is determined by the doctor, it depends on the disease.

Aerosol Hexoral, instructions for use

The instructions for use of the spray stipulate that it can be used by children after three years of age and by adults by spraying the aerosol into the mouth and throat.

To spray a single dose, this must be done for 1-2 seconds. Spray the product twice - morning and evening. If necessary, you can spray the product more often, as it is safe. The spray should be used after meals. The duration depends on the disease, it is determined by the doctor.

"Multi-tasking" drugs

• Cameton. It is classified as a combination drug. Its components are a mild anesthetic and antiseptic, chlorobutanol hydrate, camphor, which increases blood flow in the “sick” area, menthol, and eucalyptus oil. Patients rate this drug as effective at the initial stage of the disease. It is sprayed into the oral cavity in 2-3 sprays per session, the frequency of use is three to four times every 24 hours.
• Hexoral. The aerosol has a broad spectrum of action, has an antimicrobial, antibacterial effect, and successfully fights fungi. Its main component, hexethidine, among other things, “works” as a mild anesthetic. Excipients include essential oils of peppermint, eucalyptus, levomenthol, ethanol, methyl salicylate. Hexoral relieves pain, reduces cough, and “removes” swelling of the mucous membrane. Irrigation should be carried out twice a day after meals.
• Yox. Refers to sprays that have an antimicrobial effect, active against viruses, fungi, bacteria, protozoan microorganisms. The main active ingredients are povidone-iodine (iodine with a water-soluble polymer polyvinylpyrrolidone binding it), allantoin (a nitrogenous compound of natural origin). Apply two to four times a day; if necessary, use a spray every four hours.

Colds are often accompanied by a sore throat. Sore throat and pharyngitis are dangerous diseases that can cause serious complications. It is important for the expectant mother to quickly cope with the disease. During pregnancy, whenever possible, only medications that do not have a negative effect on the developing body of the child are used. To treat a sore throat, doctors prescribe local antiseptics. One of the most effective drugs is Lugol's solution with glycerin. Disputes about the advisability of its use during pregnancy continue to this day.

Overdose

The substance hexethidine is not toxic in the dosage indicated in the instructions.

If a person has swallowed a large amount of the drug, vomiting is observed, so significant absorption does not occur. There have been no recorded cases of alcohol poisoning from ingestion of the drug.

For two hours after swallowing large doses of the drug, it is necessary to perform gastric lavage and symptomatic therapy. It is important to consult a specialist after swallowing large doses of medication.

Geksoral's analogs

Level 4 ATC code matches:
Analogues of this medicine are the drugs Stomatidin , Hexosept , Stopangin , Hexetidine , etc. The doctor should select the most optimal drug.

Which is better: Inhalipt or Hexoral?

In general, the effects of these drugs on the body are similar. But Inhalipt is prescribed for a narrower range of diseases. Inhalipt is several times cheaper than Hexoral.

Hexoral for children

It should be borne in mind that this drug can be prescribed to children after reaching three years of age. The instructions for children inform that the use of the solution is possible at an age when the child is able to consciously rinse the mouth and throat, and there is no danger of swallowing the liquid.

Hexoral spray is also not used for children under 3 years of age. It is important that the child does not resist the spray nozzle in the mouth and can hold his breath while the drug is injected.

For children over 3 years of age, the product is used in the dosage indicated in the instructions.

Description of the drug Tantum Verde

The active ingredient of the drug Tantum Verde is benzydamine. This is a substance that has pronounced antiseptic and analgesic effects. Benzidiamine is able to fight against harmful bacteria and fungi. The agent penetrates the cell membrane of the microorganism and attacks it, as a result of which the bacterium dies. The analgesic effect occurs due to inhibition of prostaglandin synthesis. Benzidiamine can also destroy candida fungus in the mouth. Tantum verde is produced in the form of lozenges, spray and solution for external use.

The average price in Russia is 310 rubles.

Prescribed for:

• Laryngitis
• Pharyngitis
• Sore throat
• Stomatitis
• Glossitis
• Gingivitis
• Periodontal disease
• Candidiasis of the oral cavity.

General instructions for tantum verde can be found here.

Hexoral during pregnancy and lactation

the undesirable effects of the drug during pregnancy and lactation . Therefore, the question of whether Hexoral can be taken during pregnancy can be answered positively, but only if the doctor clearly weighs the potential benefits and risks. Regardless of whether the patient is in the 1st trimester or 2nd trimester of pregnancy, she should definitely consult with her doctor. There is no sufficient data on the effect of the drug during breastfeeding.

Geksoral price, where to buy

How much the drug costs depends on the packaging of the release form - it is an aerosol or a solution. The price of Hexoral spray is 240-260 rubles per 40 ml package. Hexoral throat spray is used as a spray for children over 3 years old.

The price of Hexoral solution is 210-240 rubles per 200 ml package. You can find out more accurately the cost at the places where the drug is sold.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine

Pharmacy 36.6

• Hexoral solution for local application 0.1% 200mlJOHNSON AND JOHNSON
• Hexoral tabs classic tablet d/rass. N16 lemonJOHNSON AND JOHNSON
• Hexoral tabs tablet d/rass. N20JOHNSON AND JOHNSON
• Hexoral tabs classic tab d/rassas N16 honey-lemonJOHNSON AND JOHNSON
• Hexoral tabs extra tab.d/rass. lemon N16JOHNSON AND JOHNSON

ZdravZone

• Hexoral tabs No. 20 lozengesSoldan Holding
• Hexoral tabs classic Orange No. 16 lozenges Unique Pharmaceutical Laboratories (Departments
• Hexoral tabs classic Lemon No. 16 lozenges Unique Pharmaceutical Laboratories (Departments
• Hexoral tabs classic Honey-lemon No. 16 lozenges Unique Pharmaceutical Laboratories (Departments
• Hexoral tabs classic Blackcurrant No. 16 lozenges Unique Pharmaceutical Laboratories (Departments

Release form

The drug is commercially available in spray and solution, the therapeutic effect of which is explained by hexethidine. It suppresses the metabolism of bacteria and has an anesthetic effect on the oral mucosa. Hexethidine is active against fungi, viruses and gram-positive bacteria; resistance to the drug does not occur. Sensitive to it:

• mushrooms of the genus Candida;
• influenza A virus;
• herpes viruses;
• RS virus;
• proteas;
• Pseudomonas aeruginosa.

The medicine is also available in tablets:

• Hexoral Tabs . A combined drug, the therapeutic effect of which is explained by chlorhexidine and benzocaine. The drug has broad antibacterial activity and has a local analgesic effect.
• Hexoral Tabs Classic. The medicinal components of the drug are amylmetacresol and dichlorobenzyl alcohol. The drug has antimycotic and antibacterial effects.
• Hexoral Tabs Extra . The therapeutic effect of the drug is explained by lidocaine, amylmetacresol, and dichlorobenzyl alcohol. The medicine exhibits antifungal activity and has an analgesic effect. It is effective against diseases caused by gram-positive and gram-negative microorganisms.

There are no separate pediatric and adult forms; the drug is available in the same dosages; only the treatment regimen changes depending on the patient’s age.