Which is better: Antigrippin, Theraflu or Coldact? What can we expect from these drugs?

Theraflu is a popular cold medicine. Its use is especially effective at the first signs of the disease. The composition of the medicine includes a whole range of components. The main active ingredients are paracetamol and phenylephrine.

Theraflu is indispensable for fever, it provides excellent pain relief, reduces swelling of the nasopharynx, eliminates itching, sneezing and other antiallergic symptoms. Ascorbic acid thins the blood and improves the immune system.

Indications for use of the drug: fever, headache, nasal congestion, chills, muscle pain, sneezing. The Swiss pharmaceutical concern produces a whole series of medicines under the Theraflu brand - syrup, spray, powders, ointments and tablets.

The most popular medicine is a powder that is diluted with boiling water and drunk hot. The magical effect of the medication appears immediately - the patient feels relief, a decrease in temperature and headache.

The main effect of Theraflu is to reduce unpleasant cold symptoms. The virus or infection that caused the disease must be treated with specific medications. For children, the use of this medicine is not recommended until they are 12 years old. Paracetamol in its composition has many contraindications, so it is taken with caution during pregnancy.

There are many analogues and close substitutes for Theraflu, which are cheaper or slightly more expensive. Cheap analogues of the drug are a popular request in pharmacies. Pay attention to the list of Russian-made drugs listed in the table.

Release form and composition

At what age is Theraflu approved for use in children? According to the instructions included with this medication, children can take it no earlier than they are 12 years old. Before this age, the use of the medication is strictly prohibited.

Theraflu has several dosage forms, each of which contains a number of active ingredients:

• paracetamol;
• phenylephrine hydrochloride;
• pheniramine maleate.

In addition to the main components, the product contains auxiliary: flavors, dyes, magnesium stearate, sucrose, calcium phosphate, povidone, macrogol, lactose and other substances.

Theraflu is a popular medicine and is available in different forms, each of which is used to achieve specific therapeutic goals:

1. The powder relieves the negative symptoms of colds. It has different flavors (raspberry, apple, cinnamon, with wild berries). This form is used to get rid of high body temperature and reduces respiratory symptoms.
2. Granules called Theraflu Immuno are used for oral resorption. They can be used after 14 years of age, they are packaged in disposable sachets. This dosage form is used to reduce fever and relieve pain.
3. Tablets (may have the prefix Forte, Extra): used only for adult patients.
4. Theraflu ointment for children can be used from 12 years of age. It is used to ease breathing and improve sputum discharge.
5. Teraflu Lar RS, available in the form of tablets and sprays, are used to treat ENT and dental pathologies. They do not have an antibacterial composition, but are used to get rid of laryngitis, pharyngitis, and stomatitis.
6. Spray or drops, have an anise flavor, are used for improved sputum discharge.

Instructions for use of the drug

The medicine "Teraflu", analogues that are cheaper and more expensive, and other similar drugs are used only after preliminary preparation. For this you will need hot drinking water. It is forbidden to dilute the medicine in tea, coffee and other drinks.

Pour boiling water into a glass and add the contents of one packet into it. After this, you need to stir the sediment with a spoon and drink the medicine. If the temperature of the drink is very high, you can wait a little and let the composition cool.

You can repeat the dose no earlier than after 4 hours. As you know, the effect of the medicine can last for a long period of time. It is worth repeating the treatment regimen only as needed. A person is allowed to consume no more than four packets of the drug per day. Otherwise, we may be talking about an overdose of the drug.

This regimen must be followed exactly as much as recommended by the doctor. The average duration of treatment is 5-7 days.

Directions for use: special instructions

Before you start using the medication, you should remember that Theraflu has clearly defined age restrictions. The drug is used no earlier than 12 years.

In addition, the instructions specify other instructions that you should pay attention to:

• long-term use of Theraflu can provoke serious hepatotoxic effects on the liver, as well as nephrotoxic effects on the kidneys;
• simultaneous use of the medicine and alcoholic beverages is not allowed, this situation will only increase the toxic effect of the medicine;
• the drug does not in any way combat the causes that caused the development of the pathological condition. Its components can only reduce the severity of negative symptoms from the respiratory system;
• the substances contained in Theraflu may well be used together with other pharmaceuticals (but before combining them, you should obtain medical advice);
• the use of the medication requires a person to temporarily stop driving vehicles and working with complex mechanisms. This is due to the fact that the drug can significantly slow down a person’s reaction time.

Despite the fact that Theraflu can be purchased without a doctor’s prescription, for the treatment of a child under 12-14 years of age, it is better to replace it with single-component formulations that are not contraindicated for a particular age.

Indications

As noted above, a newborn should not be given Theraflu under any circumstances. The medicine is approved for use no earlier than the child turns 12 years old.

Indications for the use of Theraflu are:

• cold symptoms that develop in a person after a viral infection enters the body;
• deterioration of condition, accompanied by fever, headache, nasal congestion, and other catarrhal symptoms;
• therapy of infections caused by exposure to rhinovirus, adenovirus, influenza, parainfluenza.

Comparison of addiction between Coldact flu plus and Terafly

Like safety, addiction also involves many factors that must be considered when evaluating a drug.

So, the totality of the values ​​of such parameters as “o syndrome” in Koldakt flu plus is quite similar to the similar values ​​in Terafly. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, Koldakt flu plus has a fairly small value of “syndrome”, however, the same as for Terafly.

Contraindications

Theraflu can be used not only according to age restrictions, it is important to pay attention to the physiological state of a person. There is a clear list of contraindications that do not allow the use of this medication; it is very clearly outlined in the instructions for the drug.

Contraindications to the use of Theraflu:

• high sensitivity to any component of Theraflu (main, auxiliary);
• chronic alcoholism;
• the use of drugs included in the group of MAO inhibitors, tricyclic antidepressants, beta-blockers;
• portal hypertension, with a mandatory increase in portal vein pressure;
• diabetes mellitus (types 1, 2);
• children's age (up to 12 years);
• pregnancy period;
• breastfeeding a baby.

In addition to absolute contraindications, there is a list of relative reasons when the medicine can be used only after receiving prior medical advice.

Theraflu is used with caution when:

• pronounced forms of atherosclerosis (coronary arteries);
• increased blood pressure;
• deficiency of certain enzymes;
• Angle-closure glaucoma, with increased intraocular pressure;
• congenital pathological conditions of the liver with increased bilirubin levels;
• severe pathological conditions of the liver, kidneys;
• pheochromocytoma with increased synthesis of adrenaline;
• hypothyroidism;
• prostatic hyperplasia.

Important! The drug contains many contraindications that must be excluded before starting its use.

When should the medicine not be used?

The drug "Teraflu", cheaper analogues and expensive drugs with the same composition are prohibited from being used in the following cases:

• in the presence of hypersensitivity to one of the components of the drug;
• during pregnancy and lactation;
• children under 12 years of age.

Only after consultation with a specialist can the medicine be used for diseases of the liver and kidneys, heart and prostate gland.

Overdose

• stomach pain;
• nausea;
• damage to the liver, kidneys;
• development of liver failure due to the high toxicity of paracetamol.

This condition is treated by gastric lavage and taking sorbents (activated carbon). If 8 hours have not passed since the overdose, the use of methionine is indicated. When more than 12 hours have passed, acetylcysteine ​​is used. This therapy is performed only in a hospital setting.

In addition to overdose, long-term therapy with Theraflu can provoke the formation of negative reactions in the body.

Side effects of Theraflu:

• Gastrointestinal organs: pain in the epigastric region, nausea, dryness of the oral mucosa;
• CNS: increased nervous excitability, dizziness, headache, problems falling asleep and staying asleep;
• heart and blood vessels: increased blood pressure;
• sense organs: increased pressure inside the eyes, enlarged pupils, accommodative paresis;
• circulatory system: decreased hemoglobin due to decreased red blood cells, decreased platelets, granulocytes in the blood serum;
• organs of the genitourinary system: decreased amount of urine excreted, nephrotoxic effects, excess glucose in the urine;
• skin reactions: the appearance of a rash, redness, irritation accompanied by itching, urticaria, Quincke's edema.

The occurrence of any adverse reactions requires immediate cessation of drug therapy, as well as seeking medical help.

How can an overdose occur?

An overdose of Theraflu develops in those patients who use it without following the instructions. To prevent an overdose, you need to drink the powder strictly according to the instructions, avoiding unauthorized increases in the dose or frequency of its administration.

The drug contains a lot of paracetamol, so it should not be given to children under 12 years of age (some sources set this bar higher - at the level of 15 years). Otherwise, this medication may disrupt the development of the child, having a serious hepatoxic effect on him.

The medicine has a similar effect on pregnant and lactating women. For them, taking this drug is contraindicated, otherwise it may negatively affect the baby’s health. In addition to medicinal components, Theraflu has many flavors and dyes, which are also harmful to the child’s body.

Drug interactions

The use of Theraflu does not prohibit the additional use of other medications, however, in order to avoid negative effects on the body, you must first study the instructions.

Principles of drug interactions:

• the risk of hepatotoxic effects increases when a person simultaneously takes barbiturates, rifampicins, diphenin, carbamazepine, and other liver inducers;
• urinary retention, increased dry mouth, and digestive disorders often develop when a person takes antidepressants, antipsychotics, antiparkinsonian drugs, and phenothiazine derivatives at the same time as Theraflu;
• glucocorticosteroids can cause an increase in blood pressure;
• propantheline may reduce the rate of absorption of Theraflu components;
• metoclopramide promotes accelerated absorption of the drug;
• paracetamol helps to lengthen the half-life of chloramphenicol (the time increases by 5 times);
• the excretion of paracetamol will increase, as well as the number of harmful metabolites formed, if salicylamide is taken at the same time;
• chlorzoxazone can provoke an increase in toxicity to the body, both from it and from paracetamol;
• neutropenia may increase when a person takes Theraflu and Zidovudine at the same time;
• taking the medication enhances the effect of coumarin derivatives.

How much and how to give

Theraflu powder is used exclusively for internal use; when it comes to tablets, they should be washed down with water without chewing. The powder is pre-dissolved in water, slightly cooled after boiling. Approximately 100 ml of water is suitable for this purpose.

Children over 12 years of age can take a Theraflu tablet at a time, or drink one sachet of dissolved powder. You should not take more than 4 tablets (packets of powder) per day; it is advisable to maintain equal time intervals between them.

Adult patients can take two tablets at one time (dissolve two powders) to get quick relief of symptoms. However, repeating this procedure within one day is not recommended; subsequent doses should include only one dose.

The duration of taking Theraflu is 3 days. When a person, after this period, does not observe improvements in his own condition, he should seek medical help.

Composition and dosage form

The drug is marketed in two dosage forms: tablets and powder.

The main components of the drug are:

• paracetamol;
• pheniramine hydrochloride;
• phenylephrine hydrochloride;
• ascorbic acid.

The powder form of the drug is packaged in special sachets weighing 11.5 g. One package contains 10 sachets of the drug.

Theraflu tablets are packaged in special blisters, 1 or 2 per pack.

Price category of the medicine

Depending on the number of packets in the package, the cost of the medicine may vary. So, 10 sachets will cost you about 300-400 rubles. At the same time, many pharmacy kiosks offer to purchase goods individually.

One sachet of medicine costs approximately 50 rubles. If you do a basic calculation, you can come to the conclusion that it is more profitable to buy a larger pack.

pharmachologic effect

The drug Theraflu, thanks to its components, has a whole range of actions.

Paracetamol reduces the severity of the inflammatory process. Already after the first dose of the drug, patients observe a decrease in temperature and pain.

Thanks to phenylephrine, which is contained in the drug, arterial vessels narrow and swelling of the nasal mucosa decreases.

Pheniramine has an antiallergic effect. Thanks to this component, Theraflu tablets relieve a runny nose, relieve itching, tearing, burning, and reduce swelling.

In a short period of time, the drug is absorbed into the systemic bloodstream and begins its effect. It is excreted from the body along with urine.

Description of the drug

Theraflu is a combination drug with a wide spectrum of action that has pronounced analgesic, antipyretic, and analgesic properties. The use of the drug in the treatment of viral or infectious diseases of the ENT organs and upper respiratory tract can significantly alleviate the patient’s condition.

Theraflu is a symptomatic, fast-acting drug. Its use for flu or colds allows you to relieve general symptoms within 30 minutes. The medicine is produced by the pharmaceutical company Novartis (Canada, USA, Switzerland).

Indications for use

The main indications for the use of Theraflu tablets and powder are infectious and inflammatory diseases, which are characterized by fever, body aches, runny nose, sore throat and other typical cold symptoms. The above symptoms are characteristic of influenza, adenovirus infection, etc.

Theraflu tablets and powder are intended for oral use. In the first case, the drug is chewed and washed down with a sufficient amount of water, in the second, it is diluted in ½ glass of water and taken orally.

Usually the drug is taken in 1 tablet or 1 sachet, but if necessary, in particular when symptoms are intense, the dosage of Theraflu tablets or powder can be increased to two pieces.

If the patient’s condition does not improve within 5 days, the drug should be stopped and the help of a specialist should be sought to prescribe more effective treatment.

How to make Theraflu yourself

Preparation of Theraflu does not take much time and cost; all products can be purchased in the store without much difficulty. To make this recipe you need the following ingredients:

• Quality honey
• Ginger
• Lemons.

Wash two lemons well, place in a blender and grind to a paste.

Then peel about 30 grams of ginger root, and also chop it together with lemon.

Add 2 tablespoons of honey to this thick mixture, which smells nice, and mix everything well.

The resulting mass should be transferred to a clean, sterilized jar, closed with a lid and refrigerated. The shelf life of homemade Theraflu can be 5-6 months. Its intake is 2 teaspoons, 2-3 times a day, the mixture is diluted in a glass of warm water and drunk in small sips.

In order to achieve a quick recovery, treatment must begin with the first symptoms of a cold and continue for a month, even if all signs of the disease have already been completely eliminated.

What are the contraindications?

Theraflu tablets and powder can be used in patients over 12 years of age. Taking tricyclic antidepressants and beta-blockers is a direct contraindication to the use of the drug Theraflu. The drug should not be used if the following factors are present:

• diabetes;
• portal hypertension;
• pregnancy and lactation;
• pulmonary pathologies, including bronchial asthma.

If the patient has hypersensitivity to the components of the drug, it must be replaced with another drug.

Theraflu tablets are used with caution for the following conditions:

• prostatic hyperplasia;
• arterial hypertension;
• atherosclerosis of the coronary arteries;
• angle-closure glaucoma;
• congenital liver diseases (Dubin-Johnson, Rotor, Gilbert syndrome).

The presence of at least one of the above factors excludes the possibility of taking the drug. In this case, you need to seek help from a specialist who will select treatment, taking into account the individual characteristics of the body.

Possible side effects

The use of Theraflu tablets and powder can cause side effects from the urinary, digestive, cardiovascular and nervous systems. An allergic reaction to the drug may occur. The above factors are expressed by the following symptoms:

• painful sensations in the abdomen;
• dry mouth;
• periodic dizziness or intense headache;
• increased blood pressure;
• sleep disorders;
• skin rash of various etiologies;
• decrease in the daily volume of urine excreted;
• accommodation paresis;
• constriction of the pupils;
• glucosuria (appearance of glucose in the urine).

If at least one of the above symptoms appears, you must stop taking the drug.

Comparison of the safety of Coldact flu plus and Terafly

The safety of a drug includes many factors.

At the same time, Koldakt flu plus is quite similar to Teraflu. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing the metabolism of Koldakt flu plus, as well as Therafly, we look at which organ is the metabolizing organ and how critical the effect on it is.

The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Coldact flu plus does not have any risks when used, just like Terafly.

Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Koldakt flu plus and Terafly.

Features of application

Theraflu for influenza requires careful use. It is important to carefully read the instructions contained inside the package. To avoid negative reactions of the body, you also need to know some application features:

• do not take the drug for more than 5 days. Long-term exposure to its components on the body can lead to intoxication of the liver and kidneys;
• Theraflu tablets help reduce the severity of the symptoms of the disease, but do not affect its cause;
• It is not recommended to take tablets with alcohol at the same time, as this increases the load on the liver;
• Theraflu drug interacts with other groups of drugs; before using them, you should consult a doctor;
• While taking the medication, you must avoid work that requires increased concentration.

Features of using the medicine

The drug "Teraflu", cheaper and more expensive analogues with the same composition cannot be combined with alcohol consumption. This may have increased toxicity to the liver and lead to unexpected reactions. Before consuming a portion of ethanol or drugs containing it, you must wait until the drug is completely eliminated from the body.

After using the medication, it is not recommended to get behind the wheel or drive a vehicle for some time. It is also worth postponing important work that requires increased attention.

Overdose

Exceeding the dosage of Theraflu tablets or powder can lead to negative reactions that are caused by the toxic effects of paracetamol. They are expressed by nausea, vomiting, stomach pain, liver and kidney damage. In severe cases, liver failure may develop.

Overdose treatment is carried out in a hospital setting. The patient undergoes gastric and intestinal lavage, after which he is prescribed sorbents, for example, activated carbon. If no more than 8 hours have passed since the overdose, the patient is prescribed methionine; if more, acetylcysteine ​​is used as an antidote.

Interaction with other drugs

Concomitant use of Theraflu tablets with barbiturates increases the risk of paracetamol toxicity.

The combination of Theraflu with antipsychotics, antidepressants and phenothiazine derivatives can cause urinary retention, constipation and dry mouth.

Concomitant use with glucocorticosteroids often increases intraocular pressure. Drugs that help slow gastric emptying, when taken simultaneously with Theraflu tablets, impair its absorption into the bloodstream. Medicines to speed up gastric emptying, on the contrary, speed up the absorption of the drug. Simultaneous use of paracetamol with chloramphenicol slows down the elimination of the latter by 5 times.

It is not recommended to use Theraflu simultaneously with salicylamide; this increases the excretion of paracetamol from the body and increases the risk of its toxic effects. The combination of chlorzoxazone with paracetamol increases their hepatotoxicity. The simultaneous use of Theraflu with zidovudine entails increased neutropenia; the use of paracetamol with coumarin enhances the effect of the latter.

Analogues of Theraflu

If for some reason it is impossible to take Theraflu, it can be replaced with similar drugs, of which there are many today. The following medications have a similar therapeutic effect:

• Stopgripan. The active ingredients are similar to Theraflu, the only difference is in the auxiliary components. It is produced in powder form and is characterized by a more reasonable cost.
• GrippoFlu. This is a Russian-made drug completely similar to Theraflu. Available in powder form with cranberry, raspberry, strawberry and lemon flavors.
• AntiFlu. An American drug that is identical in composition to Theraflu, but is characterized by a lower dosage of components. Available in tablet and powder form.
• Maxicold. Another domestically produced analogue of Teraflu. The main difference between these two drugs is the higher dosages of ascorbic acid and paracetamol in Maxicold.

Coldrex. It has anti-inflammatory, anti-edematous and antipyretic effects. The difference is the increased dosage of ascorbic acid and paracetamol in Coldrex. In addition, it does not contain pheniramine.

One of the popular medications for colds and illness is called Theraflu, which contains several components, which provides a complex effect on a weakened body. The manufacturer promises instant relief and elimination of the main symptoms of a cold.

Having caught a cold in damp weather or in a draft, we strive to quickly get rid of unpleasant symptoms. At the first sign of illness, we run to the pharmacy and, without hesitation, take a drug that will miraculously stop the onset of the disease. But you need to be careful when choosing a medicine. It doesn't hurt to know what's inside the promisingly advertised package.

Most often, buyers do not read what is written in the instructions, although this should be done in any case. The substances that make up the drug may not be combined with other medications or may be contraindicated for health reasons. Therefore, before you drink the medicine or give it to your loved ones, read the composition of the cold medicine. You may have to abandon this drug or replace it with an analogue.

The manufacturer who produces the medicine Theraflu promises instant relief from the burdensome symptoms of a cold. According to advertising information, this drug reduces elevated body temperature, eliminates headaches, relieves swelling of the nasal mucosa and pain in the throat.

The medicinal powder of this brand contains several active substances:

• paracetamol;
• ascorbic acid;
• pheniramine;
• phenylephrine.

Each of these substances has its own characteristics and contraindications.

The main component indicated in the instructions is paracetamol. It belongs to the class of analgesics and antipyretics. This substance has a double effect: it normalizes body temperature and relieves pain.

Ascorbic acid regulates oxidative processes, improves the absorption of carbohydrates and blood clotting. Thus, this substance improves the protective functions of the immune system.

Pheniramine, an antihistamine, eliminates lacrimation, which often accompanies colds.

Phenylephrine stimulates certain receptors, which accelerates blood flow and constricts blood vessels, helps relieve swelling in the nasal cavity and makes breathing easier.

How to replace Teraflu?

Reviews of analogues of this drug are different. It all depends on the characteristics of the composition of the medicine and its individual effect on the body of different people. What can most often replace the original product?

• Medicine "Coldact Flu Plus". This medication is available in capsule form, but has an almost identical composition. Moreover, its price will be approximately two times lower than that of the drug Teraflu.
• Antigrippin agent. This drug has the same composition as the original powder. However, its price is several times lower. The effect of treatment is similar.
• Composition of "Negreenpin". This drug also contains paracetamol, but its dose is slightly reduced. This medicine does not contain antiallergic agents. It is worth noting that some patients do not need them at all.
• Medicine "Lemsip". This drug must be diluted in the same way as Theraflu. However, it costs much less. It is worth noting that such a medicine has a similar wide variety of tastes.

In fact, there are a lot of analogues to the drug “Theraflu”. All of them have the main active ingredient – ​​paracetamol. Also, such medications include some kind of antihistamine and a large amount of vitamin C.

The dangers of paracetamol: take care of your liver

Paracetamol has an antipyretic effect, so its popularity is easily explained. The substance quickly brings down the temperature, which significantly alleviates the patient’s condition. But this coin also has a downside: paracetamol has an aggressive effect on the liver. With prolonged use or large dosages, severe destructive processes begin in the liver.

This effect of substances is called hepatotoxicity. At the same time, the risk of intoxication increases if, in parallel with paracetamol, you take other drugs that have a destructive effect on the liver. People suffering from diseases of this organ are generally not recommended to take paracetamol-based medications. If in doubt, you should consult your doctor. He will tell you which drugs should be avoided and what they can be replaced with when treating a cold.

It is because of the danger to the liver that doctors warn that alcoholic beverages should not be consumed during treatment. So if you are sick and take Theraflu as a remedy for a cold, you should temporarily give up alcohol and even low-alcohol drinks, including beer. The load on the liver is already high, and alcoholic drinks will further aggravate its condition.

However, ascorbic acid, in addition to protecting the immune system, partially protects the liver from the negative effects of paracetamol.

Vitamin C improves the tolerability of the analgesic, so this combination in the drug is more than justified.

So, using this medicine for cold symptoms is very effective, but for liver diseases, one should be extremely careful. The most important thing is to never exceed the dosage: a double dose of the drug will not speed up recovery, but will only cause side effects.

TeraFlu

Combined drug for the symptomatic treatment of colds. Available in the form of a soluble powder. It is somewhat different in composition from the drugs we discussed above: it contains a lower dosage of paracetamol, and pheniramine, phenylephrine and ascorbic acid as an anti-allergenic component.

It does not differ in indications for use - it is used for colds and flu to combat the main symptoms of the disease, it has similar contraindications, side effects and limitations of use.

Long-term uncontrolled use is dangerous for the development of acute renal failure.

Cons of Theraflu as a universal drug

It's not just paracetamol that has side effects. Other components of the medicinal powder may also adversely affect the patient's health. So you need to know the main contraindications and possible consequences of use. All of them are described in the instructions, but we will analyze them in more detail.

Phenylephrine is dangerous for those suffering from hypertension. The vasoconstrictor effect causes blood pressure to increase. So in hypertensive patients, the condition may worsen after taking the medicine.

Pheniramine is contraindicated in pregnant and lactating women. It should not be used by patients suffering from glaucoma and prostate hypertrophy.

In addition, the components of the drug can cause allergies. To some extent, an allergic reaction is prevented by the pheniramine included in the composition. But no one is immune from side effects, especially when the dosage is exceeded. Main manifestations of adverse reactions:

• itching, redness of the skin and other signs of allergies;
• sleep disturbances and overexcitation;
• impaired psychomotor functions, retardation, decreased concentration;
• increased blood pressure.

In conclusion, we can say that this drug is an effective comprehensive remedy against colds, but cannot be a panacea. Its components have both beneficial properties and side effects.

The complexity of its effects increases the number of those who should not take the drug: mainly people with liver disease, high blood pressure, as well as women during pregnancy and lactation.

INSTRUCTIONS for medical use of the drug

Registration number:

P N012063/01-310511

Trade name of the drug:

TheraFlu ® for colds and flu
INN or group name:

Paracetamol+Phenylephrine+Pheniramine+Ascorbic acid&

Dosage form:

powder for solution for oral administration [lemon].

Compound:

One sachet contains: Active ingredients:
paracetamol 325 mg, phenylephrine hydrochloride 10 mg, pheniramine maleate 20 mg, ascorbic acid 50 mg.
Excipients:
sodium citrate dihydrate, malic acid, sunset yellow dye, quinoline yellow dye, titanium dioxide, lemon flavor, tribasic calcium phosphate, citric acid, sucrose.

Description:

Free-flowing white granular powder with yellow inclusions without foreign particles with a citrus odor. Soft lumps are allowed.

Pharmacotherapeutic group:

Acute respiratory infections and “cold” symptoms are a means of elimination (analgesic non-narcotic drug + alpha-adrenergic agonist + H 1 -histamine receptor blocker + vitamin).
CodeATX:

N02BE51

Pharmacological properties:

The combined drug has antipyretic, anti-edematous, analgesic and antiallergic effects.

Indications for use:

Infectious and inflammatory diseases (ARVI, influenza), accompanied by high fever, chills, body aches, headache and muscle pain, runny nose, nasal congestion, sneezing.

Contraindications:

Hypersensitivity to individual components of the drug, simultaneous use of tricyclic antidepressants, monoamine oxidase inhibitors, beta-blockers, portal hypertension, alcoholism, sucrase/isomaltase deficiency, fructose intolerance, glucose-galactose maladsorption, pregnancy, breastfeeding, children under 12 years of age.
Carefully:

For arterial hypertension, diabetes mellitus, angle-closure glaucoma, severe diseases of the liver or kidneys, lungs (including bronchial asthma), difficulty urinating with prostate adenoma, blood diseases, congenital hyperbilirubinemia (Gilbert, Dubin-Johnson and Rotor syndromes), hyperthyroidism , pheochromocytoma. If you have one of the listed diseases, be sure to consult your doctor before taking the drug.

Pregnancy and breastfeeding

: It is not recommended to use the drug during pregnancy and breastfeeding due to the lack of data on the safe use of the drug in these individuals.

Directions for use and dosage:

Inside. The contents of one sachet are dissolved in 1 glass of boiled hot water. Consumed hot. You can add sugar to taste. A repeat dose can be taken every 4 hours (no more than 3 doses in 24 hours). TheraFlu ® for colds and flu can be used at any time of the day, but the best effect comes from taking the drug before bed, at night. If there is no relief of symptoms within 3 days after starting to take the drug, you should consult a doctor.

Side effect:

Possible allergic reactions (rash, itching, urticaria, angioedema), increased excitability, decreased speed of psychomotor reactions, feeling of fatigue, dry mouth, urinary retention, nausea, vomiting, stomach pain, palpitations, increased blood pressure, dizziness, sleep disturbance , mydriasis, accommodation paresis, increased intraocular pressure. Considering the presence of paracetamol: rarely - blood system disorders (anemia, thrombocytopenia, leukopenia, agranulocytosis), with long-term use of high doses, hepatotoxic and nephrotoxic effects, hemolytic anemia, methemoglobinemia, pancytopenia are possible. If any of the side effects indicated in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor
.

Overdose:

Nausea, vomiting, pain in the epigastric region, hepatotoxic and nephrotoxic effects; in severe cases, liver failure, encephalopathy and coma develop.
Treatment: gastric lavage, activated charcoal in the first 6 hours, administration of SH-group donors and precursors for the synthesis of glutathione-methionine 8-9 hours after an overdose and N-acetylcysteine ​​after 12 hours. Interactions with other drugs:

It is recommended to refrain from taking the drug when taking monoamine oxidase inhibitors. The risk of hepatotoxic action of paracetamol increases with the simultaneous administration of barbiturates, phenytoin, carbamazepine, rifampicin, zidovudine and other inducers of microsomal liver enzymes. Strengthens the effect of sedatives and ethanol. Ethanol enhances the sedative effect of pheniramine. Antidepressants, antiparkinsonian and antipsychotic drugs, phenothiazine derivatives increase the risk of developing urinary retention, dry mouth, and constipation.

special instructions

To avoid toxic liver damage, the drug should not be combined with alcoholic beverages. While taking the drug, it is not recommended to drive a car or use other machinery. Do not use the drug from damaged sachets.

Release form:

Powder for solution for oral administration [lemon]. For the Famar France plant. France: 22.1 g of powder in a 5-layer bag (paper/polyethylene/low-density polyethylene/aluminum foil/low-density polyethylene). 5, 6, 10 or 12 sachets in a cardboard box. The bags can be placed individually or fastened in pairs. Instructions for use are applied to the bag. For Novartis Consumer Health Inc., USA: 22.1 g of powder in a 6-layer bag (paper/low-density polyethylene/polyethylene/low-density polyethylene/aluminum foil/low-density polyethylene). 5, 6, 10 or 12 sachets in a cardboard box. The bags can be placed individually or fastened in pairs. Instructions for use are applied to the bag. Or 5, 6, 10 or 12 sachets in a cardboard box along with instructions for use. The bags can be placed individually or fastened in pairs.

Storage conditions:

At a temperature not higher than 25 °C. Keep out of the reach of children.

Best before date:

2 years. The drug should not be used after the expiration date.

Russian-made analogues

You can find similar magic powders among domestic drugs.

Medicines from Russian manufacturers differ in the composition of active substances, but have similar indications for use.

You can get acquainted with popular medicines in the table:

For just 20 rubles you can buy Coficil Plus at the pharmacy. But a similar substitute in composition is Fervex, whose cost is slightly lower than the original drug.

Carefully read the list of contraindications; many of the above medications should not be taken by children and women during pregnancy and lactation.