Features of the use of aminophylline solution in ampoules for inhalation

Efficiency and procedure for inhalation with Eufillin

Inhalation procedures, widely used today in the complex treatment of inflammatory and infectious diseases of the upper respiratory tract and nasopharynx, involve the use of a wide variety of solutions and dosage forms. One of the drugs used in these manipulations is Eufillin. This remedy belongs to the medicinal group of xanthines, and is widely used to treat obstructive bronchitis, dry cough and even bronchial asthma.

Eufillin is available in various pharmacological forms - capsules, tablets and injections and is prescribed to adults and children exclusively on the recommendation of a doctor. The action of the drug is designed to quickly expand the bronchi and release accumulated mucus and phlegm from the respiratory tract.

Aminophylline contains the main active substance in treatment - aminophylline, consisting of theophylline and ethylenediamine in a ratio of 4:1. This composition of the drug increases its absorption and effectiveness. In addition, the theophylline group of substances significantly accelerates the process of solubility and absorption of dosage forms.

Depending on the complexity of the development and course of bronchitis or asthma, the patient may be prescribed drug therapy, and inhalations based on the drug can become only an auxiliary form that facilitates and accelerates the main treatment.

The main indications for prescribing inhalation based on Eufillin to a patient are obstructive bronchitis. By aerating medicinal particles, the inhaler quickly delivers the medication to the epithelium, reduces spasms and normalizes breathing, activating contraction of the diaphragm muscles. The main feature of the drug is its ability to restore blood circulation in the lungs, improve the patency of the upper respiratory tract and eliminate excess carbon dioxide in the bronchial tissues. The use of Eufillin allows you to completely relax the bronchi, adjusting the flow of necessary nutrients into them, and completely restoring the flow and ventilation of air.

Acute and chronic forms of bronchitis, as a rule, affect the functioning of the human cardiovascular system. Insufficient oxygen supply to the blood causes the risk of developing diseases such as myocardial infarction. By lowering blood pressure on the walls of blood vessels, Eufillin is able to establish and normalize blood flow, prevent thrombosis, significantly improving the parameters and properties of blood in general.

But the main indications when a doctor prescribes inhalations with Eufillin are bronchial asthma and obstructive chronic bronchitis, pulmonary edema and ephymesis. Both adults and children are prescribed inhalations to relieve spasmodic syndromes and ease breathing.

Inhalations with the drug

The use of this medicine is indispensable for shortness of breath and obstruction that occurs in asthma. Obstructive changes gradually lead to the development of respiratory failure. It is quite difficult to prevent it with medications, but with the help of inhalations you can achieve maximum effect and alleviate complications.

About the nebulizer

Inhalations through an aerosol-type device are intended for rapid administration of the drug into the affected area of the bronchi. The smallest particles do not settle in the alveoli, but gently envelop the epithelium inside the pulmonary tree, helping to reduce swelling and irritation. After regular use of aminophylline, rapid cell regeneration is observed against the background of a decrease in the inflammatory process.

General recommendations

Eufillin is incompatible with some drugs. Even with inhalation exposure, drug inconsistency may persist. During the consultation, the doctor is informed that the child is taking all groups of medications, if they are necessary for the treatment of chronic diseases.

The drug cannot be combined with acid solutions. When taking hormonal drugs simultaneously, their side effects increase. Eufillin is not used with drugs that excite the central nervous system.
Antidiarrhea medications significantly reduce the absorption of aminophylline. They are taken an hour after inhalation.
A high therapeutic effect from aerosol therapy occurs along with the use of macrolide antibiotics. They require a reduction in the number of inhalations.
Diuretic drugs taken in parallel with aminophylline increase their effect.
It is recommended to avoid drinking strong tea and coffee.
The duration of therapy will depend on the individual characteristics of the body, the speed of normalization of the general condition and elimination of symptoms.

Inhalation with a nebulizer

Since the role of inhalation is to quickly deliver the drug to its destination, it is best to breathe Eufillin through a nebulizer. This device works faster and more efficiently than a steam inhaler. On some devices, you can adjust the desired size of aerosol microparticles (it should be different for adults and children), as well as set the delivery of the medicine “by inhalation”. In addition, the use of the device for inhalation by young children is simplified by the fact that it comes with a special children’s mask.

When using the drug, you must remember that inhalations with Eufillin do not in themselves cure the disease, but only help to expand the bronchi, cleanse and improve breathing to relieve spasms and subsequently treat bronchitis. The dosage for preparing the solution is as follows: for 1 ampoule of the product, take 3 ampoules

Diphenhydramine and 150 ml of saline solution (or purified water). If the solution is intended for procedures for children, the dosage is determined only by a specialist, depending on the age of the child and the degree of development of obstructive bronchitis.

Pharmacodynamics and pharmacokinetics

Instructions for use of Eufillin tablets provide information about its pharmacological properties. The spectrum of action of Eufillin is quite wide, since it affects not only the respiratory tract, but also the functioning of the cardiovascular system, biliary tract, urinary system, and blood pressure.

The main properties of Eufillin are as follows:

Stimulation of contraction of the diaphragm;
Decrease in vascular resistance in the lungs;
Reduced pressure in the pulmonary circulation;
Increasing the functionality of the intercostal and respiratory muscles;
Increased sensitivity to carbon dioxide;
Enrichment of blood with oxygen;
Increased number of heartbeats;
Decreased vascular tone;
Slight increase in diuretic function;
Prevents thrombus formation;
Increases acidity in the stomach;
Dilates the bile ducts.

The pharmacokinetics of Eufillin is characterized by its high bioavailability. The composition is quickly and almost completely absorbed into the tissue. The maximum concentration can be reached 1-2 hours after taking the tablet orally. Substances can pass into breast milk and also pass the placental barrier, so it is advisable not to take them during pregnancy and lactation. Manufacturers note that the concentration of active components in the child’s blood will be higher than in the mother’s blood.

Self-medication with this medicine is contraindicated, since Eufillin can actively influence various systems in the body. The appointment should only be made by the attending physician.

Reviews about the drug confirm its high effectiveness, but it is important to comply with the permissible dosage. Concentrations greater than 20 mg/ml lead to a toxicological effect.

people with pulmonary heart failure and chronic lung disease need strictly the indicated dosage, since the period of elimination of active substances with such diagnoses increases to 24 hours. The elimination process occurs through the kidneys.

For adult patients, the cost of treatment with such a drug will depend on the severity of the disease, so it is important to consult a doctor in a timely manner.

Contraindications

Eufillin is one of those medications that have a lot of contraindications, so its use as a component in inhalation solutions for adults and children and the optimal dosage must be agreed with a doctor.

Here are a number of diseases for which the use of the medication is contraindicated:

Heart failure, myocardial infarction, arterial hypertension;
Diseases of the gastrointestinal tract - ulcers, gastritis, pathologies of the intestines and rectum, chronic kidney and liver diseases;
It is necessary to use a solution with Eufillin with extreme caution during pregnancy.

In addition, any use of the drug (intravenously, orally or as a vapor for inhalation) should be calculated individually, taking into account the patient’s individual tolerance of the components contained in the drug. Be sure to consult your doctor about how to dilute the product for children in cases of acute bronchial cough attacks.

Eufillin is one of those medications that, with long-term use, changes the overall picture of the blood, lowering the glucose content in its composition. The use of the drug is not recommended for small children under 3-4 months of age!

If the drug is used incorrectly and in overdose, Eufillin can cause side effects. These are hypotension, nausea, vomiting, headaches, and stomach upset. A high concentration of the solution can cause damage to the mucous membrane of the nasopharynx.

In physiotherapy rooms of medical institutions, inhalations with Eufillin for adults and children are prepared based on large volumes of the drug. However, after consulting with a doctor and determining the individual dose and composition of the medicinal solution, you can carry out procedures at home using a compression nebulizer.

Recommendations for the use of this drug, dosage and frequency of procedures for adults and children are determined only by a specialist, based on a complete examination, taking into account the patient’s chronic diseases and contraindications.

Contraindications for the use of aminophylline

A drug of this medicinal effect should not be used for a number of contraindications:

General intolerance to the drug, in particular to the substances it contains, such as aminophylline or xatin derivatives.
Acute stage of coronary heart disease, such as myocardial infarction.
Hypertrophic cardiomyopathy with obstruction.
In case of pathological disturbance of heart rhythm.
Stomach ulcer.
Deviations in the functioning of the genitourinary system, kidney disease.
Chronic human neurological diseases such as epilepsy.
When the body's metabolic processes slow down.

Never prescribed in combination with the drug Fedrin.

Injections of this drug are prohibited in the following situations:

high sensitivity to the active components of aminophylline;
chest discomfort syndrome;
acute heart failure syndrome;
heart rhythm disturbances;
blood pressure surges;
accumulation of fluid in the lungs;
chronic arterial diseases;
involuntary bleeding;
frequent seizures;
damage to the hypothalamus;
excessive levels of hormones in the thyroid gland;
endocrine syndrome;
congenital malfunctions of hemoglobin metabolism in the circulatory system of the human body;
sepsis;
disorders of the kidneys and liver.

Eufillin solution is not recommended for children under 14 years of age ; it is prescribed in times of emergency, if vital signs require it. The same is with intravenous injections, only after the age of three, and no longer than a two-week course.

What is the drug

The main active component of the drug aminophylline is aminophylline, which belongs to the theophylline group. Available commercially in the form of tablets, capsules and liquid for injection. The drug has an antispasmodic, non-selective effect, which is expressed in the following effects:

relief of allergic reactions accompanied by bronchospasm;
quick relief from the symptoms of acute bronchitis;
restoration of circulatory function in the lungs and bronchi.

Eufillin is prescribed for various respiratory disorders, pathologies of the respiratory system, cystic fibrosis, emphysema, bronchial asthma associated with physical stress and chronic obstructive bronchitis.

Persons suffering from uncontrolled cardiac arrhythmia, high blood pressure and gastric ulcers accompanied by bleeding are not recommended to use the drug.

It is worth understanding that inhalations in themselves do not have a therapeutic effect, and are only an auxiliary means for alleviating negative symptoms as part of complex therapy.

Indications for use

Before using aminophylline, you should understand in detail the indications for its use. The drug is used for:

chronic and obstructive bronchitis;
severe pulmonary edema;
bronchial obstruction and bronchospasm;
severe coughing attacks;
excessive production of sputum in large quantities.

If the drug is prescribed to a child, the doctor's prescription should be treated with caution. The medicine is prescribed to children under 6 years of age only in extreme cases and in very severe forms of bronchitis. In this case, the minimum dosage of this drug must be strictly adhered to and its use must be under the supervision of an experienced doctor, since children very often experience serious side effects from taking the medicine.

Proper use of Eufillin for inhalation in a nebulizer

The instructions for using Eufillin in ampoules for inhalation warn patients about the importance of following the prescribed dosages, since even a slight excess can lead to a number of disastrous consequences .

In order to reduce the body's reaction to the process of histamine production, the doctor may prescribe diphenhydramine or another antihistamine along with the drug.

The algorithm for using aminophylline for adults using a nebulizer is as follows:

First, a physiological sterile sodium chloride solution or from one to one and a half milligrams of an injection solution is mixed in the apparatus.
Then add a similar amount of aminophylline with a concentration of 2.4%.

One inhalation involves the use of a solution in a volume of 3 ml. The remaining liquid cannot be placed in a refrigerator for storage because each procedure requires the use of a new solution.

The duration of inhalation should not exceed seven minutes. If allergic rashes, dizziness or other unpleasant sensations occur during the procedure, it should be stopped immediately.

How to use inhalations with Eufillin for children? The dosage and duration of inhalation procedures should be determined by the attending physician, who must take into account the individual characteristics of the child, as well as carefully study his medical history.

When the optimal dosage has been selected for children, inhalations can be carried out at home using a compression nebulizer. The interval between procedures should be at least seven to eight hours.

General dosage recommendations are as follows:

For children under 6 years of age, use no more than 0.5 ml of the drug for one inhalation, the number of which should not exceed 3 per day.
The optimal dosage for children under 12 years of age is 1 ml, while the number of inhalation procedures can reach 4 per day.
Adult patients are usually prescribed double the adolescent dosage, the number of inhalations should be identical.

Find out if you can do inhalations during pregnancy.

Eufillin in most cases does not cause side effects when combined with drugs such as prednisolone, diphenhydramine and salbutamol. The drug in tablet form is not suitable for preparing an inhalation solution, since the design of aerosol nebulizers assumes the ability to work exclusively with solutions.

Exceeding the dosage leads to damage to the mucous membranes of the nasopharynx and the occurrence of a number of side effects, including: diarrhea, headache, nausea and high blood pressure.

Important! The drug is contraindicated in arterial hypertension, heart failure, pathologies of the liver, kidneys, gastritis, ulcers and other diseases of the gastrointestinal tract.

For use during pregnancy, consult a qualified healthcare professional. Children under four to five months of age are prohibited from using aminophylline in any form.

Eufillin for children

The main indications for the use of aminophylline in children are considered to be chronic inflammatory disease of the respiratory tract with attacks of shortness of breath, degradation of the structure of the lung tissue, impaired blood and lymph circulation, as well as diseases with increased blood pressure.

The drug aminofillin contains the following contraindications:

a decrease in pressure by more than 20% of the original;
increase in heart rate from 90 beats per minute;
disruption of the normal rhythm of myocardial contractions;
ulcerative defect on the wall of the stomach.

Secondary effects include diarrhea, headaches, nausea, syndrome of increased nervous excitability, pain in the abdominal cavity, frequent beating, and a sharp decrease in blood pressure. When the drug is administered into the rectum, irritation of the rectal mucosa may be observed.

Note! Prescribing medicine to children without a doctor's prescription is prohibited! The instructions for use note that children under 3 years old should not be prescribed the medicine either rectally or intramuscularly. Therefore, parents should use medications with caution, especially for children, and follow the doctor’s advice.

At this age, any medications are prescribed in precise dosages.

At the age of fourteen years, the drug can be prescribed, however, in the form of enemas. However, only when the child has a serious illness, so the doctor, despite the huge list of secondary signs, prescribes medicine. The main thing is not to exceed the permissible dose, otherwise all the various secondary effects will negatively affect the general state of well-being.

In case of acute need, aminophylline tablets for a dry cough in a child are prescribed in a dosage of approximately 5 ml per kg of body weight. It is necessary to adhere to the exact time between doses of the drug. For example, a one-year-old child with a cough caused by inflammation of the bronchi is allowed to take the medicine no more often than once with an interval of eight hours.

When the baby is more than six months old, the time is reduced to six hours. For older children, the intervals are the same, however, the dose of the substance is reduced to 4 mg. Very rarely, with a protracted disease, the dose needs to be increased. The child must be administered up to 16 mg of the substance. The dosage during the day does not exceed 400 mg. It is better to distribute the total dose into four doses of Eufillin.

When secondary manifestations have not appeared and health is improving, the dosage, on the advice of the doctor, is increased by one fourth. This is the maximum dosage, which is 500 mg per day.

When treating infants, doctors more often prescribe electrophoresis with Eufillin, due to the fact that the medicine does not enter the body directly, but is used to wet the gasket of the device. Electrophoresis improves blood circulation, saturates cartilage tissue, and thins mucus in the respiratory tract.

Inhalation procedures for a child with Eufillin are determined with caution, because at an early age the threat of the formation of secondary signs increases, higher than in adults.

Despite the specifics of use and possible side reactions, Eufillin remains an effective medicine. When used correctly, it will bring exceptional benefits to the body and help remove unpleasant signs of protracted illnesses in the shortest possible time.

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Considering the restrictions on taking the drug in childhood and the likelihood of adverse side effects, only a doctor should determine the indications for its use.

Eufillin is indicated for conditions such as:

An attack of bronchial asthma;
Apnea (temporary cessation of breathing) in premature newborns;
Cerebral circulatory disorders caused by ischemia;
Respiratory failure due to heart failure (left ventricular);
Heart failure, acute and chronic;
Broncho-obstructive syndrome of various origins;

It is important that, based on official indications, Eufillin should not be used at home. Only a doctor can prescribe the drug, determine its dosage and method of administration.

Physiotherapeutic treatment with aminophylline is also common through the penetration of the substance using an electric current - electrophoresis. Indications for its use are such conditions as:

Consequences of perinatal damage to the central nervous system of various origins;
Movement impairment syndrome;
Consequences of cervical spine injuries;
Decreased muscle tone;
Delay in psycho-physical development;
Intracranial hypertension.

Physiotherapeutic techniques in combination with drug therapy, exercise therapy and massage have a significant impact on the pathology of the nervous system, promoting the normal development of the child.

Inhalations with aminophylline - all the pros and cons of this treatment

Eufillin is used in the treatment of bronchopulmonary pathologies to facilitate breathing. The drug relieves spasms, expands the lumen of the bronchial tubes, redirects pulmonary blood flow, and stimulates cardiac activity. Eufillin for inhalation is used in children and adults. Using medicine in this way raises many doubts and disputes among medical practitioners. However, patients note the effectiveness of inhalation with aminophylline.

Features and properties of aminophylline

The treatment method using inhalation with a nebulizer has proven itself to be the best. Eufillin acts directly at the site of inflammation. Inhalation of fine particles leads to a rapid reduction in the manifestations of acute bronchitis. The drug in aerosol form does not settle, but gently envelops the affected inner surface of the bronchial tree.

The drug in tablets is not suitable for preparing the solution, since a solution with suspended particles cannot be poured into aerosol inhalers. Even if the compressed medicine is well crushed and dissolved, microscopic particles will remain in the liquid. This may damage the nebulizer.

The active substance of the drug is aminophylline, which contains a component of the theophylline group. Thanks to this, inhalations with a nebulizer with aminophylline are considered particularly effective, as they are quickly absorbed and have a direct maximum effect.

Action of the solution:

direct contact with the inflamed epithelium;
spasm relief;
normalization of breathing;
activation of the diaphragm muscles;
restoration of blood circulation in the lungs;
improving the patency of the upper respiratory tract;
elimination of excess carbon dioxide in tissues;
maximum relaxation of the bronchi, which reduces coughing;
restoration of air flow and ventilation function.
prevention of thrombosis;
improvement of blood properties.

purulent, prolonged, acute, chronic bronchitis;
obstruction;
pulmonary failure;
cough of any form - dry, wet, smoker's;
bronchial asthma;
pneumonia;
irritation of the mucous membrane lining the throat;
pharyngitis, laryngitis, tracheitis.

Eufillin has a lot of beneficial properties, but also has many side effects and limitations. Before using it, you should consult your doctor regarding the duration of use and dosage. After this, you can safely begin the inhalation course.

Eufillin for inhalation

Euphylline is a combination drug consisting of theophylline and ethylenediamine. The pharmaceutical industry produces medicine in three forms:

Tablets, dosage 150 mg
Solution for intravenous administration in ampoules (concentration 2.4%)
Solution for intramuscular administration (concentration 24%)

Note! There is no special release form of aminophylline as a solution for inhalation.

Opponents of inhalations with aminophylline motivate their position by the fact that such procedures are pointless and can provoke bronchospasm. Their negative attitude is explained by the peculiarity of the drug’s action.

Eufillin, as a drug with a systemic effect on the body, has a therapeutic effect only if it is used “centrally”, through the blood. It does not have a local effect on the mucous membrane when using inhalers. The relief of breathing is explained by the effect of saline solution on the mucous membrane.

Effect of the drug

Eufillin has a non-selective antispasmodic effect. This means that when taking the medicine and reaching a therapeutic dose of aminophylline in the patient’s blood, the following happens in his body:

the tone of smooth muscles of all organs and systems decreases
the lumen of the bronchial tubes expands
the intensity of heart contractions increases
tone is removed from blood vessels
peripheral blood supply and blood supply to the brain improves
pressure decreases noticeably
diuresis increases due to improved blood supply to the kidneys
biliary tract relaxes
acid content in gastric juice increases
in pregnant women, the tone of the uterus is removed
the intensity of contractile spasms of the intestinal muscles decreases

Note! The therapeutic dose of the drug differs slightly from its toxic dose. The use of aminophylline should be carried out under the supervision of a physician.

Procedures with euphilin, if the solution is properly diluted and there is no individual reaction to it, do not lead to an overdose of the drug in the blood.

Indications for use in bronchopulmonary pathologies

Regarding respiratory diseases, aminophylline is prescribed:

for asthma to relieve and prevent bronchospasm
for obstructive bronchitis for the same indications
with allergic reactions of the body accompanied by bronchospasm

Eufillin injections are prescribed during an exacerbation of the disease or to provide emergency medical assistance in relieving an attack of suffocation. In maintenance and preventive therapy, aminophylline is taken in tablet form several times a day, the dosage depends on the doctor’s prescription.

Warnings and contraindications

Children and adults are prohibited from using aminophylline without consulting a doctor, especially if they are encountering the drug for the first time. An individual reaction similar to a reaction to an overdose is possible.

convulsive syndrome
drop in blood pressure
nausea, vomiting, heartburn
dizziness, loss of orientation
palpitations, rhythm disturbance

During treatment, you should not drink a lot of coffee, since the drug is converted into caffeine during absorption.

Fact! Strong coffee can make breathing easier. People with chronic asthma attacks are well aware of this feature.

The drug is incompatible with theophylline and ephedrine (which are often contained in cough syrups, including those for children). When used together, an overdose effect occurs.

The drug is not used:

for heart pathologies associated with rhythm disturbances
for gastropathologies, intestinal ulcers
for severe renal/liver failure
for hypothyroidism

Use caution if the patient has low blood pressure. Eufillin in any form is prohibited for use by children at home without medical supervision.

Side effects

Complete contraindications for use are:

stomach ulcer during exacerbation;
gastritis due to increased acidity;
epilepsy;
very low or very high blood pressure;
hemorrhage on the retina;
arrhythmia;
hemorrhagic stroke.

The drug should be taken with particular caution in case of vascular atherosclerosis, myocardial infarction, acute angina, liver or kidney failure, prolonged fever, elderly patients, during pregnancy and breastfeeding, as well as bleeding.

Like other medicines, Eufillin can cause various side effects. Do not forget about this before starting treatment and carefully read the instructions. The following reactions may occur from different organs:

dizziness;
insomnia;
overexcitement;
irritation and anxiety;
pain in the cardiac region;
tachycardia;
arrhythmia;
arterial hypotension;
vomit;
nausea;
appetite disorders;
intestinal disorders;
heartburn;
stomach pain.

Bronchodilating, tocolytic, antispasmodic, diuretic. Belongs to a group of drugs for systemic use in diseases that are accompanied by obstruction (obstruction syndrome) of the respiratory tract.

Clinical and pharmacological group (according to the Vidal reference book): bronchodilator - PDE inhibitor. Pharmaceutical subgroup - xanthines.

Side effects of using Eufillin tablets:

sleep disturbances, anxiety, dizziness, convulsions, tremor;
irregular heart rhythm, palpitations;
hematuria, albuminuria;
hypoglycemia (rare).

Against the background of injection therapy, the following are possible:

headache, anxiety, dizziness, agitation, irritability, tremor, insomnia;
arrhythmias, tachycardia (including in the fetus, if the woman took the drug in the 3rd trimester of pregnancy), palpitations, cardialgia, decreased blood pressure, unstable angina;
nausea, diarrhea, heartburn, gastralgia, vomiting, exacerbation of symptoms of peptic ulcer, GER, with long-term use - loss of appetite;
itching of the skin, skin rashes, fever;
tachypnea, chest pain, hypoglycemia, albuminuria, increased diuresis, hematuria, increased sweating, feeling of heat in the face.

Side effects are dose-dependent, that is, to relieve them, it is often enough to reduce the dose of the drug.

Local reactions to the injection of the solution manifest themselves in the form of skin hyperemia, pain and the formation of a seal at the injection site.

Instructions

How to properly use aminophylline during inhalation for inhalation in ampoules? For procedures with aminophylline, spraying is used through a nebulizer - a special device that sprays the therapeutic solution to the smallest particles without heating it. Steam inhalers are not used for treatment in this case. When inhaled, the aerosol obtained in the nebulizer enters directly into the trachea and bronchi, where it settles.

How to perform inhalation:

During the procedure with aminophylline, you should correctly inhale through your mouth and exhale through your nose
procedure time 5-8 minutes
the solution should not be cold

Note! The official instructions for use of the drug do not provide instructions regarding inhalation. The manufacturer does not provide for such use of the drug.

The effect of the drug on the body as a whole

Although Eufillin is given to a child for coughing, it is considered a broad-spectrum drug. In addition to the main effects that help relieve the symptoms of an inflammatory disease, the drug has a number of other beneficial properties.

It inhibits platelet aggregation, helping to reduce the risk of thrombosis.
It has the ability to expand the extrahepatic bile ducts, promoting the outflow of bile. This helps relieve pain during exacerbations of cholecystitis.
Due to its hypertensive properties, it reduces the tone of the walls of blood vessels, which helps lower blood pressure.
"Eufillin" significantly increases renal blood flow, while having a moderate diuretic effect.
Finally, this drug is able to prevent the deformation of red blood cells.

Immediately after this drug, it is absorbed into the blood as quickly as possible, reaching the peak of its effect approximately at the end of the second hour after administration. It is necessary to ensure that its concentration in the blood does not exceed 10-20 micrograms per millimeter of blood. If the content of this drug exceeds the established norm, poisoning of the entire body is likely to occur. This is something to be wary of, since Eufillin is highly toxic.

In this regard, it is of great importance that patients and their relatives should carefully study the instructions for using Eufillina tablets for children with cough. In most cases, it is prescribed in a hospital setting so that it is possible to monitor the content of this drug in the blood. It is important to emphasize that monitoring of its content in the blood must be carried out even in cases where it is discharged for a long period or during outpatient treatment. Otherwise, there is a risk of becoming a victim of serious disorder in case of overdose.