Characteristics of the medication
Nasonex spray belongs to the category of hormonal drugs.
Made in Belgium. Sold in a bottle made of durable plastic with a dispenser for approximately 120 - 140 doses. Nasonex has positive reviews from specialists and patients. It relieves symptoms of diseases well, and is especially effective in combating nasal congestion.
Anna R. Ryazan: I suffered from allergic symptoms all year round. Runny nose, lacrimation, did not go away. Doctors prescribed many medications. Some helped, some brought temporary relief. There was no obvious positive result. When I switched to Nasonex I felt better. The nasal congestion went away quickly, the other symptoms a little later. I like the medicine and will continue to take it, despite the high price. I don’t want to use similar means, I’m afraid the effect will disappear.
Yuri M. Kazan: Runny nose and nasal congestion were constant signs of spring and autumn. He was treated with many medications. I've heard both good and bad reviews about Nasonex. Many people are afraid that it is hormonal. But with my runny nose, I took so many antibiotics that spraying hormones into my nose doesn’t seem so scary anymore.
Svetlana Alekseeva Tuapse: I had vasomotor rhinitis for a long time. I constantly used vasoconstrictor drops, without them it was not possible to live even one day, or sleep one night. With such swelling of the mucous membrane, some doctors suggested surgery, but they said that this was still not a solution. The swelling will still continue.
Nasal products for children
Finding safe nasal medications for the treatment of rhinorrhea in children is the most difficult. Children's bodies are susceptible to sensitization (hypersensitivity to allergens), so many topical medications cause adverse reactions in them. To eliminate rhinitis and nasal congestion in the youngest patients, it is recommended to use the following types of drops:
- based on silver (“Collargol”, “Protargol”) – disinfect the nasal cavity and prevent the development of microbial and fungal infections;
- oil (Sinupret, Pinosol) - quickly relieve inflammation and normalize metabolic processes in affected tissues;
- based on sea salt (Salin, Humer) - restore the microflora in the nasopharynx and moisturize the mucous membrane.
In newborns and infants, the nasal passages are quite narrow, so putting viscous oil drops into the nose only worsens congestion. To facilitate nasal breathing in the youngest patients, it is recommended to suck out mucus from the nasal passages with aspirators, and then instill moisturizing children’s drops - “Otrivin Baby”, “Aqua Maris Baby”, “Dolphin”, etc.
Composition and release form
Each dose of Nasonex contains 50 mcg of mometasone furoate in the form of monohydrate, the substance is an active GCS (glucocorticosteroid).
The composition contains as auxiliary ingredients:
- dispersed cellulose;
- glycerol;
- sodium citrate dihydrate;
- distilled water;
- citric acid hydrate;
- phenylethyl alcohol.
The bottle has a plastic dosing valve. There is no children's release form, so the dosage is selected taking into account the patient's age.
Indications for use
Used to treat runny nose of allergic origin, year-round and seasonal allergic rhinitis in children from 2 years of age and in adults.
The spray is used to prevent seasonal allergic rhinitis. It is recommended to start using the drug a month before flowering.
Can be used in the treatment of chronic sinusitis as an adjuvant in combination with antibiotic therapy. In this situation, use is recommended for children over 12 years of age and adults.
Therapeutic effect
Nasonex has the following effects:
- Antipruritic;
- Antiallergic;
- Anti-inflammatory;
- Vasoconstrictor.
Nasonex spray, according to the instructions for use, has a noticeable effect on the lining of the nasopharynx. It also has a vasoconstrictor effect on the vessels of the sinuses. As a result, swelling decreases and inflammation of the tissues of the nasal cavities decreases.
Symptoms are relieved and the patient’s well-being improves. During a course of treatment with a spray, relapses occur less frequently than when using other medications of the same category.
During medical tests, the spray was found to be highly effective in relieving allergies. For allergic rhinitis, the therapeutic effect occurs 12 hours after using the medication. Increased lacrimation, burning and redness of the eyes quickly disappear. Nasonex can be used to get rid of polyps and normalize the sense of smell. He copes with these problems effectively.
Composition of the drug
Nasonex is an original Belgian drug. It is used as a local medicine with anti-inflammatory and anti-allergic effects to relieve inflammatory processes . The active ingredient in it is synthetic corticosteroids.
What does the spray look like?
The product in one dose contains 50 mcg of anhydrous mometasone furoate and the additions: glycerol, benzalkonium chloride; dispersed cellulose, polysorbate 80; phenyl alcohol, citric acid, sodium citrate, purified water, monohydrate.
The peculiarity of the drug is that it acts only in the area of the mucous layer. It does not enter the systemic bloodstream , which means that there are no consequences.
Thus, this feature of the drug allows one to avoid insufficiency of the hypothalamic-pituitary-adrenal system, even when the drug is used for a long time. And when the drug penetrates from the nasopharynx into the stomach, mometasone quickly disintegrates and is excreted by the kidneys or liver.
It is permissible to use the drug only in a dose when there are no systemic manifestations. The treatment regimen and duration of use of the drug Nasonex is determined only by the doctor based on the data of laboratory tests completed, taking into account individual tolerance to the drug.
Numerous clinical studies of the drug have shown that it is safe for different age groups and effective at all stages of inflammatory diseases of the nasal cavity. Through comparative studies, it was found that mometasone is 10 times stronger than other corticosteroids : beclomethasone, betamethasone, hydrocortisone and dexamethasone.
Nasonex for rhinitis
The drug is available in two forms: Nazones and Nazones Sinus. The suspension of both forms itself is whitish in color. Note that the substance should be used as an aerosol , but not as drops. If you are wondering what the difference is between Nasonex and Nasonex sinus, then we will touch on this issue in more detail.
Use for allergies
Nasonex spray is a classic steroid for intranasal use. Refers to active hormonal drugs. Contains a safe concentration of corticosteroids - the bioavailability of mometasone when applied topically as a spray is only 0.1%, which reduces the risk of developing serious side complications.
The product is available only in the form of a spray with a volume of 60 or 120 doses.
Nasonex has a powerful anti-inflammatory and persistent antiallergic effect. Clinical studies of the drug have proven that the active hormone in the composition is able to reduce swelling and nasal congestion during allergies, both in the early and late stages.
The drug demonstrates a positive effect on respiratory tract reactions. Symptoms typical of allergies are reduced - congestion, tearing, itching and burning. The product is effective in the treatment of already manifested allergies, in contrast to antihistamine nasal sprays.
We also recommend that you read the material on how to treat allergic rhinitis during pregnancy at this link.
Depending on the characteristics of the therapy, the drug may cause various side effects during the treatment period. For allergic rhinitis in adults and children, the following reactions are possible:
- headache;
- pharyngitis;
- burning sensation, dryness in the nose;
- sneezing.
Find out how to stop nosebleeds here.
Epistaxis during treatment with hormonal sprays is a typical reaction of the body to the active substance. They are usually not severe and go away on their own in a short period of time. When treating sinusitis with Nasonex, irritation of the mucous membrane may occur. If such a sign is detected, the drug should be stopped.
It is not recommended to use Nasonex simultaneously with other glucocorticosteroid drugs, regardless of the form of release. This contributes to the inhibition of the functioning of the endocrine glands (hypothalamus, pituitary gland and adrenal glands). Overdose of hormonal drugs and prolonged therapy leads to disruption of metabolic processes in the body and the development of systemic autoimmune diseases.
The drug should be taken with caution together with vasoconstrictors for topical use, because they increase dryness and irritation of the nasal mucosa.
Nasonex according to the instructions is used in the treatment and prevention of rhinitis, which can last all year round or be observed only in the off-season. In these cases, two doses, that is, sprays, will be prescribed per day for each nostril. When improvement occurs, the dose of Nasonex is reduced.
If the appearance of pathology does not go away, then the number of injections is increased, but the maximum dosage (400 mg - 4 injections) cannot be exceeded. For children over two years old, one injection is prescribed for each nasal passage once a day. The instructions for use do not recommend exceeding the dosage of Nasonex.
Treatment of “drip addiction” or drug-induced rhinitis
Frontitis
, vasomotor rhinitis, medicinal rhinitis, “nasal drip dependence”, medicinal runny nose - all these terms are used in relation to the same pathological condition that occurs with prolonged uncontrolled use of large doses of decongestants (although it is worth immediately noting that treatment with decongestants does not affect vasomotor rhinitis causes - its nature is not related to drug effects).
What leads to the development of this pathology?
During the off-season, many people experience acute respiratory viral infections (ARVI) and exacerbation of chronic diseases of the ENT organs (rhinitis, sinusitis), a common manifestation of which is a runny nose. And not every sick person turns to a doctor for treatment recommendations, but almost everyone goes to the pharmacy for freely sold drops for the common cold.
Since ancient times, humanity has resorted to sympathomimetics (vasoconstrictor drugs) when treating the runny nose: ephedrine was used for these purposes more than 5 thousand years ago, and in the 19th and early 20th centuries, otolaryngologists often resorted to cocaine during manipulations.
Of course, today Cocaine or Ephedrine cannot be found in a pharmacy - medicine has invented many modern vasoconstrictor drugs (decongestants), which often occupy a separate display case in pharmacies. These drugs are among the most popular medicines among the people: according to data for 2010.
In Russia, 221 million packages of nasal vasoconstrictor drugs were sold, i.e. 1.5 packs per person per year.
All modern decongestants for intranasal (through the nose) use are classified as adrenergic agonists, i.e.
substances that, due to direct stimulation of adrenergic receptors of vascular smooth muscles, cause an effect similar to the effect of norepinephrine - vasoconstrictor.
There are various types of adrenergic receptors in the nasal mucosa, but the main processes occurring during a runny nose are realized through α2-adrenergic receptors, so the effect of most local decongestants is on them.
These are drugs based on:
- xylometazoline (“Galazolin”, “Afrin”, “Otrivin”);
- oxymetazoline (“Nazivin”, “Nazol”);
- naphthazoline (“Naphthyzin”, “Sanorin”);
- tramazoline (“Adrianol”, “Rinospray”).
There are also drugs based on phenylephrine
(“Nazol Baby”, “Nazol Kids”), which acts selectively on α1-adrenergic receptors and does not have a significant negative effect on local blood flow in the mucosa. For this reason, the effect of phenylephrine drugs is not as pronounced and as long-lasting as that of drugs of the first group, but the risk of developing “drip dependence” due to their use is also lower.
Effect of cold drops
based on the following mechanism: α-adrenergic receptors are stimulated ⇒ the vessels of the mucous membrane narrow, their permeability decreases ⇒ swelling of the mucous membrane and the amount of exudate (discharge from the nose) decreases ⇒ the volume of the nasal cavity and the air stream passing through it increases, breathing becomes freer.
Features of the pharmacological effect of decongestants
the fact that they act quite quickly, intensively and for a short time (except for xylometazoline preparations, which provide an effect within 10-12 hours). These features provoke the patient to actions leading to the development of drug-induced rhinitis.
A patient suffering from a runny nose, after taking the drug, as if by magic, regains freedom of breathing, begins to smell, and the nasal voice and the need for a handkerchief disappear. But after a couple of hours, the symptoms of rhinitis return, and your health worsens.
But I want to improve it again! And, without looking at the instructions, a person begins to instill the medicine more and more often... But it is no coincidence that the instructions for using decongestants clearly state that they can be taken no more than 2-4 times a day and no more than 7 days: if the frequency and duration are violated When used, the drug molecule blocks adrenergic receptors, as a result of which the sensitivity of vascular smooth muscles to endogenous norepinephrine decreases, “paralysis” of the vessels occurs, and they lose the ability to narrow.
Tachyphylaxis (addiction to the drug) and the so-called “rebound syndrome” develop when a vasoconstrictor drug, instead of reducing the symptoms of rhinitis, increases them.
In addition, clinical studies conducted in recent years have shown that the development of this pathology can be potentiated not only by the action of the decongestant itself, but also by the action of the stabilizer included in the preparations for the common cold - benzalkonium chloride.
This component has a ciliotoxic effect, i.e. has a detrimental effect on the cells of the nasal mucosa, causing irritation, hypersecretion of mucus and inhibition of the functioning of goblet cells.
Thus, the main cause of rhinitis medicamentosa
– uncontrolled treatment of a runny nose with vasoconstrictor drugs in violation of the frequency and duration of their use specified in the instructions.
The most pronounced negative effect on the nasal mucosa is caused by naphazoline-based remedies for the common cold.
(in many countries they are even prohibited for use in pediatrics), while phenylephrine preparations do not cause significant disturbances of local blood flow in the nasal cavity and are less likely to cause drug-induced runny nose (treatment of rhinitis with phenylephrine preparations is also permitted in children under one year of age). Speaking about the forms of drugs, it is worth noting that medicinal rhinitis is most often provoked by decongestants in the form of drops - unlike aerosols, they are difficult to dose, which provokes the risk of excessive administration of the drug.
Symptoms of drug-induced rhinitis
So, with prolonged irrational use of decongestants in the nasal mucosa, changes such as:
- remodeling of columnar ciliated epithelium into stratified squamous epithelium with subsequent atrophy of the mucosa;
- disruption of goblet cells, leading to increased mucus production;
- increased permeability of the capillary wall, causing pronounced local edema.
These changes lead to the appearance of pathological symptoms that torment a person and force him to think about how to get rid of drip addiction:
- there is constant discomfort, burning, dryness in the nose;
- there is a feeling of constant congestion, breathing problems;
- hyposmia develops (decreased sense of smell);
- there is constant mucous discharge from the nose (although in some cases there may be none at all).
As a rule, symptoms worsen when lying down and at night.
When performing rhinoscopy, the doctor can also see a characteristic symptom: the normally pale pink mucosa acquires a rich bright red color.
If vasoconstrictors are used in doses and with the frequency specified in the instructions, they do not have a systemic effect on the body. But an overdose
medications that occurs in a patient with drug-induced rhinitis can worsen the person’s general condition and manifest itself with
symptoms
as:
- headache;
- sleep disturbance;
- instability of blood pressure;
- tachycardia (increased heart rate);
- unpleasant sensations in the heart area (even pain).
How to get rid of medicinal rhinitis
The main goal in the treatment of drug-induced rhinitis
– reduce the amount of decongestants used to zero, restoring the normal structure and tone of the vessels of the nasal mucosa.
And when asked about how to treat medicinal rhinitis, it is worth noting that an adult has a better chance of getting rid of it: many drugs for the treatment of “drip addiction” are contraindicated for children under 2 years of age.
Therefore, parents should be doubly scrupulous in following the instructions when giving medicine to their child!
Today, the main drugs in the treatment
For drug-induced rhinitis,
topical corticosteroids
(local hormonal drugs) are used.
These include nasal sprays containing: mometasone furoate (Nasonex), fluticasone furoate (Avamys), fluticasone propionate (Nazarel), beclomethasone dipropionate (Aldecin, Nasobek) and budesonide (Tafen, "Budoster")
The effect of these drugs is realized by suppressing hypersecretion of mucosal glands and reducing the production of substrates responsible for the development of local edema (eosinophils, T-lymphocytes, leukotrienes and other inflammatory mediators).
In addition, they reduce the hypersensitivity of the receptors of the nasal mucosa to external irritants. As a result, the main symptoms of “drip addiction” will decrease: nasal congestion, constant nasal discharge, impaired sense of smell.
Local corticosteroids begin to act approximately 12 hours after the start of use, the expected therapeutic effect develops within several days and sometimes several weeks.
Topical corticosteroids are practically not absorbed into the systemic circulation and are well tolerated by the patient.
Only in rare cases can undesirable effects such as nosebleeds and perforation of the nasal septum occur, but their development is usually associated with a violation of the rules for taking the drug (directing the drug stream not towards the lateral wall of the nasal cavity, but towards the septum).
As mentioned above, they can treat drug-induced rhinitis mainly in adults: mometasone and fluticasone are approved for use in children only after 2 years, and beclamethasone, due to its high bioavailability (ability to be absorbed into the systemic bloodstream) - only in children over 6 years of age.
But how to treat medicinal rhinitis if local hormones do not help? In such cases, a short course of systemic hormonal anti-inflammatory drugs (glucocorticosteroids)
.
Treatment of drug-induced rhinitis with their help eliminates the symptoms of the disease quickly enough, but due to the risk of developing various complications (sometimes as serious as steroid diabetes, osteoporosis, ulcerative lesions of the gastrointestinal tract), it is recommended to take them for the shortest possible period of time, no more than 3 -7 days. Prednisolone tablets are usually prescribed in small doses (up to 15 mg per day).
irrigation therapy can help in the treatment of drug-induced rhinitis
.
It means the use of sterile solutions of sea water to moisturize the mucous membrane, reduce the viscosity of mucus and the severity of local edema.
These solutions are widely represented in the pharmacy chain in the form of drops, sprays, nasal douches, and rinsing solutions (Dolphin, Aqualor, Marimer, Otrivin, Aquamaris, etc.). The high safety of these drugs allows their use even in infants.
Unfortunately, there are such severe forms of drug-induced rhinitis, which can only be gotten rid of through surgery.
surgical treatment methods are used for this pathology
- Submucosal vasotomy
(surgery to remove part of the blood vessels of the nasal mucosa to reduce swelling). Vasotomy can be performed using cryodestruction (destruction of tissue by freezing), electrocoagulation (cauterization), radiofrequency coagulation (destruction using radio waves), laser destruction (cauterization of vessels with a laser). - Conchotomy
(removal of part of the hypertrophied nasal turbinates, aimed at increasing the volume of the nasal cavity). Conichotomy can also be performed in various gentle ways.
The operation is most often performed under local anesthesia, the recovery period after it is short, and the patient quickly feels relief. But if after surgical treatment a person begins to abuse decongestants again, the symptoms of the disease will return again.
How else can you treat drug-induced rhinitis?
Physiotherapy , in addition to medicinal and surgical treatment methods, demonstrates high effectiveness for “drip addiction”
.
In the complex treatment of drug-induced rhinitis, methods such as ultraviolet irradiation of the nasal cavity, UHF, halotherapy
(salt inhalation treatment),
magnetic therapy, and heat therapy are used.
Speaking about physiotherapeutic methods, it is worth noting that modern medicine offers special devices
, which combine several factors of physical influence, which certainly increases the effectiveness of the treatment process.
For example, there is a portable device for home use that allows for combined effects on the nasal cavity with heat, magnetic and infrared radiation.
The influence of these physical factors helps to reduce swelling of the nasal mucosa and reduce the hyperproduction of mucus by goblet cells, which as a result reduces the symptoms of drug-induced rhinitis and allows a person to breathe freely.
Compact sizes, the presence of special nozzles for the nose, and ease of operation greatly facilitate the procedure and make it possible to independently treat yourself at home, without having to visit a clinic. Similar physiotherapeutic devices can be purchased at pharmacy chains and medical equipment stores.
Having talked about how to cure medicinal rhinitis, I would like to emphasize measures to prevent it
, because it’s easier to prevent the development of “drip addiction” than to think about how to get rid of it. In order to avoid becoming a victim of drug-induced rhinitis, you should:
- strictly follow the instructions regarding the dose, frequency and duration of use of the drug;
- if possible, give preference to decongestants that act on α1-adrenergic receptors and do not contain benzalkonium chloride;
- If you have a persistent runny nose, immediately consult a doctor to get qualified help.
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Source: https://zen.yandex.ru/media/id/5a374eb9799d9d14428c76c6/5acb5ed74bf161ef0d74025d
Main Application
The wide influence of the active substance on the body allows it to be used for various manifestations of allergies and inflammation. Nasonex according to the instructions is used for the following diseases:
- Allergic rhinitis, which manifests itself in the off-season and all year round;
- For the prevention of severe and moderate forms of seasonal allergic rhinitis;
- Polyps of the nasal sinuses and passages, which, when growing, interfere with nasal breathing;
- Chronic sinusitis during exacerbation;
The spray showed good effectiveness in the treatment of prolonged inflammation of the nasal passages. Nasonex is often used in complex treatment of nasopharynx with other medications. The drug effectively reduces nasal congestion in many pathologies.
Antiviral drugs
This type of drops is used for the prevention and treatment of viral diseases of the nose. Pharmaceutical drugs are made from donor cells or created through genetic engineering. The products are able to combat the proliferation of viruses. They are taken when there is a high risk of infection
, during the first signs of ARVI and until complete recovery:
- Gripferon is a solution for instillation into the nasal passages.
- Tamiflu and Arbidol capsules.
- Rectal suppositories Viferon and Kipferon.
- Remantadine tablets.
Today there are a lot of remedies for the treatment of the runny nose and making a choice is not difficult. But you need to remember that they must be prescribed by a doctor
, after diagnosis, since taking the wrong drug will not only not improve the condition, but can also lead to complications, one of which is drug-induced rhinitis.
Restrictions on use
According to reviews from patients and specialists, the use of Nasonex is effective. But its use is subject to limitations.
The use of the spray is contraindicated for the following diseases and conditions:
- Personal intolerance to the ingredients of the medication;
- Infection in the nasal mucosa;
- Age restrictions;
- Recent surgery or trauma to the nose with disruption of the nasal mucosa (after healing, the spray is used).
In special cases, Nasonex spray is prescribed for tuberculosis, an untreated infection with eye damage.
No special studies have been conducted, so it is difficult to definitively answer whether Nasonex can be used while carrying a child and feeding him breast milk. The use of the drug intranasally (through the nose) does not allow the main components to enter the circulatory system. If you do not exceed the therapeutic dosage, no harm will be caused to the body.
But Nasonex is a glucocorticosteroid, that is, a hormonal medication. Its effect on a woman’s body when carrying a child and breastfeeding it can be unpredictable; it is better to eliminate any risk at this time. If a woman took hormonal medications while expecting a baby, then newborn babies must be examined for early detection of adrenal hypofunction.
More about addiction to nasal drops - my experience
I’ve already come across several posts here from comrades with a problem similar to mine - severe dependence on nasal drops that relieve nasal congestion (tizin, sanorin, afrin, etc.). Many have described their relief from this really nasty thing called rhinitis medicamentosa
.
Everyone wrote that treatment is difficult, it takes a strong will to overcome this illness. I want to share my fresh experience and tell you how to simply, painlessly and effectively get rid of this nasty problem, or at least reduce it to a minimum. So, my addiction to drops has lasted about 2.5 years. A long autumn runny nose, accompanied by large doses of Sanorin, got me hooked on the drops. Before starting treatment, I used the drops 4-5 times a day, without them my nose would become completely clogged from speaking, and I could only breathe through my mouth. I woke up at night to spray it in my nose, went to a 24-hour pharmacy when the drops suddenly ran out, and spent, well, probably about 1.5-2.5k a month on them. At the same time, natural drops, such as pinosol with eucalyptus, did not help me. They tried only vigorous chemical vasoconstrictors. In general, what did the ENT advise me (or rather, my girlfriend with a similar problem). We will need
only 2 drugs (I’m not advertising, just informing) - “Polydex” for treatment and “Vibrocil” for assistance.
Polydex in Moscow pharmacies costs about 600 rubles, based on my feelings I can say that a bottle will most likely be enough for the entire course, Vibrocil - about 300 rubles, you will need 2-4 bottles, depending on how often your nose is stuffy. I personally liked Vibrocil better in the spray, but it’s almost nowhere to be found, there are drops everywhere. In total, the entire treatment will cost approximately 1.5k. What we do:
We drip Polydex 4 times a day, 2 drops into each nostril, Vibrocil - according to how you feel, when your nose is completely blocked - we drip to clear your breath.
Accordingly, Polydexa treats us, and Vibrocil helps us not to go crazy and not suffocate while the course of treatment is ongoing (it is not as vigorous as Sanorin or Tizin, so at the beginning of the course it worked for me personally not for 3-4 hours, but for half an hour or an hour) . Effect.
In the first 3-4 days, most likely, you will not feel anything - your nose is still stuffy, Vibrocil is dripped regularly. However, on about the 5th day, I began to notice that I no longer needed to drip Vibrocil every hour, my nose did not become clogged to the point of “nostrils or nostrils are a piece of cake,” at least one nostril was breathing tolerably. Now it’s the 9th day, my nose is no longer stuffy, I instill Vibrocil at night and 1, maybe 2 times during the day. Polydex is running out, I have one day left, I think I can cope without it. The main thing is to give up Vibrocil in time - you can also get hooked on it. My girl had a similar effect, it was more difficult for her, because there is also an allergy mixed in with the addiction, but she too has almost gone away. I hope it will be useful to someone :)
source
Side effects of nasal spray
The spray is prescribed by the attending physician; independent use of hormonal drugs is strictly not recommended due to the high likelihood of side effects. Nasonex is used:
- for the treatment of seasonal and year-round allergic rhinitis for adults and children over 2 years old;
- as part of the treatment of drug-induced, vasomotor rhinitis during an exacerbation in adults and adolescents. Also suitable for the treatment of chronic vasomotor rhinitis.
- as part of complex therapy for sinusitis (usually in the form of sinusitis) for adults, children over 12 years of age;
- as a preventive measure for the development of hay fever 2-4 weeks before the start of the pollination season.
Find detailed information about treating vasomotor rhinitis at home here.
The drug has many contraindications; before the first dose, you should carefully study the instructions for use. The main ones:
- hypersensitivity to any component of the composition;
- inflammatory and infectious process in the respiratory system;
- postoperative period;
- tuberculosis;
- age up to 2 years.
Nasonex is acceptable for use during pregnancy and lactation, since when administered intranasally, the hormone is practically not absorbed into the intestines or blood plasma. There is no reliable data on the potential harm of the drug to the fetus, so the spray should be used with caution. However, doctors do not recommend taking any hormonal drugs in the 1st and 2nd trimester.
Analogs
Popular analogues of the drug are presented in the table below.
Name | Active substance | Peculiarities | Use in children | average price |
Avamis | Fluticasone furoate | A glucocorticosteroid-based product for topical use. The effectiveness of the drug is higher than that of Nasonex. Moderate absorption of the active substance into the bloodstream is possible (systemic action) | Allowed for children over 6 years old | 600 rub. |
Desrinitis | Mometasone | Has a similar effect to Nasonex | Allowed for children over 2 years old | 390 rub. |
Nazarel | Fluticasone propionate | Hormonal agent acting at the level of the nasal mucosa | Allowed for children over 4 years old | 340 rub. |
Manifestation of adverse reactions
Negative manifestations occur when the dosage is exceeded or the body is intolerant to the medication. In case of severe adverse reactions, a replacement for Nasonex is selected. In most cases, the drug is well tolerated, all manifestations are temporary and go away on their own without medical help.
Negative manifestations in adult patients:
- Nosebleeds;
- Pharyngitis;
- Burning in the throat and nasal passages;
- Irritation of the nasopharyngeal mucosa.
Children more often complain of itching, burning in the nasopharynx, increased sneezing, and pain in the head. In exceptional cases, hormonal medications increase intraocular pressure or perforation of the nasal septum occurs.
For what diseases is the solution prescribed?
Nasonex spray is intended for the treatment of allergies and low-grade inflammation of the upper respiratory tract.
Main indications for use:
- continuous rhinitis (runny nose) due to irritation by an allergen, which lasts for a year or more;
- hay fever - inflammation of the mucous membranes of the nose and eyes in response to exposure to a seasonal allergen;
- complex treatment for acute and subacute sinusitis;
- nasal epithelial polyps are benign neoplasms;
- prevention of polypous rhinitis with severe forms of pollen allergy (hormonal solution begins to be instilled a month before the plant is expected to bloom).
Instructions: method of use and dosage
Before you start using Nasonex, the instructions for use explain how to calibrate. It is needed to determine the standard delivery of the suspension to the mucous membrane. To do this, press the bottle dispenser ten times, calibration will occur automatically. If this bottle does not work for more than two weeks, then another calibration will need to be done.
The bottle is shaken before each injection, and the nasal passages are cleared of congestion. Then the active substance of Nasonex will act directly on the problem area. If the nozzle becomes clogged from constant use, you must disassemble the dispenser according to the instructions. Rinse and dry the removable parts and reassemble.
According to the instructions, Nasonex is used intranasally. Injections are carried out using a dispenser on the bottle, alternately into each nasal passage.
Age | Dosage (how much to drip) |
Children from 2 to 11 years old | 1 inhalation into each nasal passage 1 time per day, maximum daily dose – 100 mcg. |
Children from 11 years old, adults | During the period of exacerbation - 2 injections into each nasal passage 1 time per day; during recovery with maintenance treatment, the dosage is halved. The maximum dose is 200 mcg. |
Before first use, you should configure the dispenser. To do this, you need to press the nozzle 6-7 times, due to which the same type of drug delivery is achieved. If treatment is necessary after a long break, the procedure can be repeated.
How to use Nasonex?
The dosage of Nasonex should be prescribed by the attending physician, but according to the instructions for use of the drug, children over 12 years of age are recommended to take 2 nasal injections into each nostril once a day. If the patient’s well-being begins to improve, the number of injections can be reduced to 1 time per day.
A maximum of 4 injections per day can be carried out simultaneously, no more.
The use of Nasonex in children aged 2 years and older is recommended only according to the strict indications of the attending physician. Children are allowed 50 mcg of the drug per day, that is, this is less than one injection (literally one small spray).
As a rule, patients feel better 12 hours after using the drug.
Features of therapy
The use of Nasonex spray for more than 1 year can lead to irreparable changes in the mucous membrane of the nasopharynx. To exclude such tissue disorders, patients should visit an otolaryngologist for a preventive examination. Also, the ENT doctor will be able to detect a fungal infection in the nose, which will be invisible to the person. In this case, stop using Nasonex spray.
In case of prolonged irritation of the mucous membrane from the use of Nasonex, analogues are prescribed.
If patients had previously used hormonal drugs and then began to use Nasonex, they should be monitored for the development of a deficiency in the functioning of the adrenal cortex. With the abolition of hormonal drugs, there is a risk of symptoms of conjunctivitis and allergic eczema. These pathologies have been present in the body for a long time, their development was restrained by the hormonal medications used.
Doctors should warn that the use of hormonal drugs sharply reduces immunity. Contact with infectious patients (especially chickenpox) increases the risk of infection. During seasonal illnesses, increased safety measures must be taken.
Differences in forms and effect
In terms of their effect, both drugs are the same. The main difference is the number of doses in the vials. Nasonex metered-dose spray is available in a plastic container and weighs 18 g. The bottle comes with a nozzle for convenient spraying. The product is enough for 140 uses.
Nasonex Sinus dosed spray in a bottle contains 10 g of the drug. A spray bottle is also included. The contents of the bottle are enough for 60 doses. This form of the drug has a volume 2.5 times less, so the price is proportional.
The principle of action of the drugs is that the active substance has a suppressive effect on the production of mediators that trigger the inflammatory process in the body when an irritant penetrates it. This reduces the mass of mucus in the sinuses, and reduces the processes of infiltration and granulation.
Which form of the drug is best to take?
The medicine copes with any stage of allergy. It blocks histamine and prostaglandins, inhibits cell proliferation. By blocking the reaction to the irritant, the manifestations of standard allergic reactions are prevented: runny nose, itching, swelling, redness, sneezing.
Nasonex is also actively used for vasomotor rhinitis , which is most often accompanied by complications in the form of sinusitis, as well as polyps. The spray copes well with swelling and inflammation. In addition, Dizrinit is used in the treatment of runny nose. Read here what is the difference between the drugs.
If incorrect therapy for the disease is prescribed or immunity is reduced, an infectious runny nose can become chronic or complicated by sinusitis.
Drugs - analogues
If it is impossible to use Nasonex, the doctor prescribes analogues. They are cheaper, but have the same composition. The following medications can replace the spray:
- Desrinitis. Relieves nasal congestion, swelling of the nasopharynx, helps with allergic rhinitis. It is a hormonal agent. Approximate price 400 rubles.
- Avamis. A hormonal remedy that helps reduce the symptoms of allergies and sinusitis. Prescribed for the treatment of polyps. Easily tolerated, has few restrictions. The price starts from 500 rubles.
- Flixonase. Produced in Poland. Effectively helps with nasal congestion of various origins. It relieves swelling of the nasopharyngeal mucosa well, reduces tissue inflammation during prolonged colds. Has few restrictions for use. Price from 430 rubles.
Analogs to Nazonex are selected only by a doctor. It will take into account the characteristics of the body, the presence of chronic diseases, and the possibility of developing complications. It is difficult to say which drugs are better - Nasonex or Avamis or other drugs. Often the choice depends on the individual characteristics of the patient’s body, especially for children. Self-medication and independent drug replacement are not allowed.
This drug is not cheap. The average market price of Nasonex spray for 120 doses is 840 rubles, 60 doses can cost 490 rubles. There are not many drugs on sale for the treatment of allergic and vasomotor rhinitis, sinusitis with mometasone as an active substance. The most accessible analogues (replacement) in the form of a spray are Dezrinit (Israel), Avamis, Nosephrin, Momat Rino, Asmanex Twistheiler (USA).
Also, for the treatment of allergic rhinitis, doctors recommend using the Erius remedy, which this article will talk about.
Instructions for use of Nasonex drops
On our project. More diseases. Ordering medications. First aid. Ask a Question. Nasonex vasoconstrictors. Good afternoon. The child is 5 years old. We visited an ENT doctor and he said that the child’s nose was inflamed, so to speak, the turbinates of the nose were enlarged.
Tell me, the child started taking this medicine and we caught a cold. We had snot running and our nose was stuffy. Is it possible to use vasoconstrictor drops and Nasonex at the same time??? What's the sequence? Is it necessary to interrupt the course prescribed by the ENT doctor? Thank you very much for your answer!!! Answered by Leskov Ivan Vasilievich. Now, against the background of an infection, it is better to cancel Nasonex altogether, and the treatment must include either nasal rinsing and isofra, if the discharge is thick and opaque, or inhalation with interferon, if the discharge is clear and watery.
And when the discharge stops, regardless of the state of nasal breathing, do a rhinocytogram and, based on its results, determine whether it is necessary to continue using Nasonex or not. Unfortunately, there are no such medications in our country. I am afraid to interrupt the prescribed treatment. In general, is it possible to use vasoconstrictors and Nasonex at the same time? The doctor assured that the likelihood of getting sick with Nasonex is low. We rinse the nose. Thanks for answering! Leskov Ivan Vasilievich. Unfortunately, Nasonex does not treat infections and does not help the nasal mucosa become an obstacle to infections.
All it does is suppress local immunity and thereby mask acute infections of the mucous membrane. So, personally, I rarely prescribe this drug. Based on the results of the consultation received, please consult a doctor, including to identify possible contraindications. Order the required drug with delivery to the nearest pharmacy. Similar questions. Vasoconstrictor drops for nasal congestion. A four-year-old child had a stuffy nose.
Vasoconstrictor drops were dripped at night for four days. It's been 10 days since the last instillation and now my nose is stuffy again. Please tell me if it is vasoconstrictor or harmonious. My question is, which of two evils, as they say, is the lesser, considering that the gestation period is 16 weeks.
I tried not to drip anything, but Hello, please tell us, the ENT doctor prescribed us to drip Nazonex for a month and a half. We have grade 1 adenoids. But the child’s nose is stuffy, is it possible to take vasoconstrictor drugs along with Nasonex? The child is 3 years old. Still gm Can the pressure rise from vasoconstrictor drops. I’m 22 and my blood pressure goes up every day. I’ve been using the drops for 5 months now. I can’t help but use it, my septum is deviated, it’s hard to breathe.
If I don't drip, my head hurts. What can you recommend instead of drops? I will have the operation soon. Adenoids and Nasonex. X-ray of the nasopharynx and the appointment of Nasonex. Good afternoon!!! Child 9 years old. At night he breathes through his mouth. Let's go to the lore. After the examination, he asked if there were any bruises on the bridge of the nose. The injury was a child falling from a bicycle at the age of 4 years Nasonex, treatment of allergic rhinitis, child 3 years old.
A 3 year old child was diagnosed with Allergic rhinitis. Subscribe to us. News Health Mail. Information is provided for reference purposes. Do not self-medicate. At the first sign of disease, consult a doctor. Ru About the company Advertising. Editorial Our experts Agreement with consultants Help.
Features of the drug use
During long-term treatment (several months or more), the nasal mucosa is regularly diagnosed to exclude possible structural changes. If a fungal infection develops in the nose and sinuses during long-term therapy, then temporarily stop taking Nasonex. The patient is given special antifungal treatment. In case of severe irritation of the epithelium, the aerosol should be discontinued:
- The drug does not affect the growth, physical and mental development of children.
- Long-term use of the spray does not disrupt the functioning of the endocrine system and the production of various groups of hormones.
- Despite the fact that the suspension is used nasally, with prolonged use symptoms of inflammatory damage to the conjunctiva of the eye may develop.
- Patients who switch from treatment with general corticosteroids to Nasonex should be closely monitored. Abrupt withdrawal of systemic hormones causes adrenal insufficiency. In some cases, with a positive trend of influence on the nasal mucosa, steroid withdrawal syndrome may develop - pain in the joints and muscles, chronic fatigue, loss of strength, depression.
It should be remembered that systemic hormones reduce the reactivity of the immune system. Therefore, patients are advised to avoid contact with infected people during periods of increased epidemiological conditions in autumn and winter , especially those diagnosed with chickenpox, measles, and scarlet fever.
If during treatment there are signs of an acute infectious process in the body - a sharp rise in body temperature to high values, severe toothache or headache, swelling of the face, a noticeable deterioration in general condition, you should immediately consult a doctor. Continued use of Nasonex will only worsen the situation.
With long-term therapy, Cushing's syndrome sometimes develops - chronic effects on the body of high doses of adrenal hormones, especially cortisone.
The drug does not interact with the antihistamine Loratadine. There is no information that Nasonex and alcohol are incompatible.
Nasonex drops are an effective topical drug. When used correctly, it is absolutely safe and does not affect internal organs and environments. The medicine helps get rid of allergies, and as part of a complex treatment eliminates inflammation and swelling of the paranasal sinuses. Side effects occur infrequently and are associated with an overdose of the suspension.
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Nasonex for adenoids
Adenoids are one of the common diagnoses heard in the otolaryngologist’s office. The disease is characterized by pathological proliferation of lymphoid tissue of the nasopharyngeal tonsil, which leads to breathing difficulties, voice changes, prolonged runny nose, and night snoring. Adenoids not only worsen the patient’s quality of life, but also increase the risk of developing otitis media, hearing loss, contribute to the formation of malocclusion, etc. Most often, children aged 3-7 years are confronted with the disease, although adults can also suffer from adenoiditis.
Treatment with conservative methods is possible only in the early stages of the disease; if the adenoids grow to an impressive size, then they need to be removed. Therefore, you should seek qualified medical help as early as possible.
Nasonex is a drug that has a pronounced anti-inflammatory effect. It is often prescribed for the treatment of adenoids that are caused by an allergic component.